Last update :
08/02/2023
References   References 182  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/54/1/56

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Trissel LA, Gilbert DL, Martinez JF.
Title : Compatibility of granisetron hydrochloride with selected drugs during simulated Y-site administration.
Reference : Am J Health-Syst Pharm ; 54: 56-60. 1997

Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Not rated: compatibility study only

List of drugs
InjectionAciclovir sodium Antiviral
Compatible 7 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionAllopurinol sodium Antigout
Compatible 3 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionAmifostine Cytoprotective
Compatible 10 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionAmikacin sulfate Antibiotic
Compatible 5 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionAminophylline Various
Compatible 2.5 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionAmphotericin B Antifungal
Incompatible 0.6 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionAmpicillin sodium Antibiotic
Compatible 20 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Sodium chloride 0,9%
InjectionAmpicillin sodium - sulbactam sodium Antibiotic
Compatible 20/10 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Sodium chloride 0,9%
InjectionAmsacrine Anticancer drug
Incompatible 1 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionAztreonam Antibiotic
Compatible 40 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionBleomycin sulfate Anticancer drug
Compatible 1 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Sodium chloride 0,9%
InjectionBumetanide Diuretic
Compatible 0.04 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionBuprenorphine hydrochloride Analgesic
Compatible 0.04 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionButorphanol tartrate Analgesic
Compatible 0.04 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionCalcium gluconate Electrolyte
Compatible 40 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionCarmustine Anticancer drug
Compatible 1.5 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionCefazolin sodium Antibiotic
Compatible 20 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionCefepime dihydrochloride Antibiotic
Compatible 20 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionCefonicid sodium Antibiotic
Compatible 20 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionCefoperazone sodium Antibiotic
Compatible 40 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionCefotaxime sodium Antibiotic
Compatible 20 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionCefoxitin sodium Antibiotic
Compatible 20 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionCeftizoxime sodium Antibiotic
Compatible 20 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionCeftriaxone disodium Antibiotic
Compatible 20 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionCefuroxime sodium Antibiotic
Compatible 30 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionChlorpromazine hydrochloride Anxiolytic
Compatible 2 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionCiprofloxacin lactate Antibiotic
Compatible 1 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionClindamycin phosphate Antibiotic
Compatible 10 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionCo-trimoxazole Antibiotic
Compatible 4/0.8 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionDactinomycin Anticancer drug
Compatible 10 µg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionDiphenhydramine hydrochloride Antihistamine (H1)
Compatible 2 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionDobutamine hydrochloride Cardiotonic
Compatible 4 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionDopamine hydrochloride Cardiotonic
Compatible 3.2 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionDoxycycline hyclate Antibiotic
Compatible 1 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionDroperidol Neuroleptic
Compatible 0.4 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionEnalaprilate Antihypertensive
Compatible 0.1 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionEtoposide Anticancer drug
Compatible 0.4 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionFamotidine Antihistamine (H2)
Compatible 2 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionFilgrastim Various
Compatible 30 µg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionFloxuridine Anticancer drug
Compatible 3 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionFluconazole Antifungal
Compatible 2 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionFludarabine phosphate Anticancer drug
Compatible 1 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionFluorouracil Anticancer drug
Compatible 16 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionFolinate calcium Cytoprotective
Compatible 2 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionGallium nitrate Calcium-lowering agent
Compatible 0.4 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionGanciclovir sodium Antiviral
Compatible 20 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionGranisetron hydrochloride Antiemetic
Compatible 0.05 mg/ml + InjectionAciclovir sodium 7 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionAllopurinol sodium 3 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionAmifostine 10 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionAmikacin sulfate 5 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionAminophylline 2.5 mg/ml + Glucose 5%
Incompatible 0.05 mg/ml + InjectionAmphotericin B 0.6 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionAmpicillin sodium 20 mg/ml + Sodium chloride 0,9%
Compatible 0.05 mg/ml + InjectionAmpicillin sodium - sulbactam sodium 20/10 mg/ml + Sodium chloride 0,9%
Incompatible 0.05 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionAztreonam 40 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionBleomycin sulfate 1 mg/ml + Sodium chloride 0,9%
Compatible 0.05 mg/ml + InjectionBumetanide 0.04 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionBuprenorphine hydrochloride 0.04 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionButorphanol tartrate 0.04 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionCalcium gluconate 40 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionCarmustine 1.5 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionCefazolin sodium 20 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionCefepime dihydrochloride 20 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionCefonicid sodium 20 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionCefoperazone sodium 40 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionCefotaxime sodium 20 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionCefoxitin sodium 20 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionCeftizoxime sodium 20 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionCeftriaxone disodium 20 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionCefuroxime sodium 30 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionChlorpromazine hydrochloride 2 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionCiprofloxacin lactate 1 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionClindamycin phosphate 10 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionCo-trimoxazole 4/0.8 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionDactinomycin 10 µg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionDiphenhydramine hydrochloride 2 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionDobutamine hydrochloride 4 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionDopamine hydrochloride 3.2 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionDoxycycline hyclate 1 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionDroperidol 0.4 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionEnalaprilate 0.1 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionEtoposide 0.4 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionFamotidine 2 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionFilgrastim 30 µg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionFloxuridine 3 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionFluconazole 2 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionFludarabine phosphate 1 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionFluorouracil 16 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionFolinate calcium 2 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionGallium nitrate 0.4 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionGanciclovir sodium 20 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionHaloperidol lactate 0.2 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionHeparin sodium 100 UI/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionHydrocortisone sodium succinate 1 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionHydromorphone hydrochloride 0.5 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionHydroxyzine dihydrochloride 2 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionIdarubicin hydrochloride 0.5 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionImipenem - cilastatin sodium 10 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionLorazepam 0.1 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionMagnesium sulfate 100 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionMelphalan 0.1 mg/ml + Sodium chloride 0,9%
Compatible 0.05 mg/ml + InjectionMethylprednisolone sodium succinate 5 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionMetoclopramide hydrochloride 5 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionMetronidazole 5 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionMinocycline hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionMitomycin 0.5 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionMitoxantrone dihydrochloride 0.5 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionNalbuphine hydrochloride 10 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionNetilmicin sulfate 5 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionOfloxacin 4 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionPaclitaxel 1.2 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionPethidine hydrochloride 4 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionPiperacillin sodium 40 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionPiperacillin sodium / tazobactam 40/5 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionProchlorperazine edysilate 0.5 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionPromethazine hydrochloride 2 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionRanitidine hydrochloride 2 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionSargramostim 10 µg/ml + Sodium chloride 0,9%
Compatible 0.05 mg/ml + InjectionSodium bicarbonate 84 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionTeniposide 0.1 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionThiotepa 1 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionTicarcillin / clavulanic acid 31 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionTobramycin sulfate 5 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionVinblastine sulfate 0.12 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionVinorelbine tartrate 1 mg/ml + Glucose 5%
Compatible 0.05 mg/ml + InjectionZidovudine 4 mg/ml + Glucose 5%
InjectionHaloperidol lactate Neuroleptic
Compatible 0.2 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionHeparin sodium Anticoagulant
Compatible 100 UI/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 1 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionHydromorphone hydrochloride Analgesic
Compatible 0.5 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionHydroxyzine dihydrochloride Anxiolytic
Compatible 2 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionIdarubicin hydrochloride Anticancer drug
Compatible 0.5 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionImipenem - cilastatin sodium Antibiotic
Compatible 10 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionLorazepam Anxiolytic
Compatible 0.1 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionMagnesium sulfate Electrolyte
Compatible 100 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionMelphalan Anticancer drug
Compatible 0.1 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Sodium chloride 0,9%
InjectionMethylprednisolone sodium succinate Anti-inflammatory
Compatible 5 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionMetoclopramide hydrochloride Antiemetic
Compatible 5 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionMetronidazole Antiparasitic
Compatible 5 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionMinocycline hydrochloride Antibiotic
Compatible 0.2 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionMitomycin Anticancer drug
Compatible 0.5 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionMitoxantrone dihydrochloride Anticancer drug
Compatible 0.5 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionMorphine sulfate Analgesic
Compatible 1 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionNalbuphine hydrochloride Antidote
Compatible 10 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionNetilmicin sulfate Antibiotic
Compatible 5 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionOfloxacin Antibiotic
Compatible 4 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionPaclitaxel Anticancer drug
Compatible 1.2 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionPethidine hydrochloride Analgesic
Compatible 4 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionPiperacillin sodium Antibiotic
Compatible 40 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionPiperacillin sodium / tazobactam Antibiotic
Compatible 40/5 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionProchlorperazine edysilate Neuroleptic
Compatible 0.5 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionPromethazine hydrochloride Antihistamine (H1)
Compatible 2 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionRanitidine hydrochloride Antihistamine (H2)
Compatible 2 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionSargramostim Various
Compatible 10 µg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Sodium chloride 0,9%
InjectionSodium bicarbonate Electrolyte
Compatible 84 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionTeniposide Anticancer drug
Compatible 0.1 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionThiotepa Anticancer drug
Compatible 1 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionTicarcillin / clavulanic acid Antibiotic
Compatible 31 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionTobramycin sulfate Antibiotic
Compatible 5 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionVancomycin hydrochloride Antibiotic
Compatible 10 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionVinblastine sulfate Anticancer drug
Compatible 0.12 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionVinorelbine tartrate Anticancer drug
Compatible 1 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
InjectionZidovudine Antiviral
Compatible 4 mg/ml + InjectionGranisetron hydrochloride 0.05 mg/ml + Glucose 5%

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