Last update :
07/10/2024
Antifungal   Fluconazole  
injection
Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Diflucan Australia, Austria, Belgium, Canada, Croatia, Denmark, Finland, Great Britain, Italy, Luxembourg, Netherlands, Norway, Poland, Portugal, russian, Slovenia, Spain, Sweden, Switzerland, United States of America, Venezuela
Elazor Italy
Exomax Italy
Flucand Saudi Arabia, Tunisia
Flucofex Turkey
Fluconax Croatia
Fluconazol Brazil, Germany, Luxembourg
Fluconazole Canada
Fluconovag Argentina
Flumycon Poland
Fungustatin Greece
Loitin Spain
Lumen Turkey
Mycomax Poland
Mycosyst Poland
Triflucan France, Turkey
Compatibility   injection   Compatibility : Fluconazole              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
injection Fluconazole 2 mg/ml
injection Aciclovir sodium 10 mg/ml
None 256
Compatible
injection Fluconazole 2 mg/ml
injection Aciclovir sodium 10 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Aldesleukin 0.0338 MUI/ml
Glucose 5% 36
Compatible
injection Fluconazole 2 mg/ml
injection Allopurinol sodium 3 mg/ml
Sodium chloride 0,9% 307
Compatible
injection Fluconazole 2 mg/ml
injection Amifostine 10 mg/ml
Glucose 5% 3
Compatible
injection Fluconazole 2 mg/ml
injection Amikacin sulfate 20 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Amikacin sulfate 5 mg/ml
None 256
Compatible
injection Fluconazole 0.5 & 1.5 mg/ml
injection Aminophylline 1 & 2 mg/ml
NaCl 0,9% or Glucose 5% 262
Compatible
injection Fluconazole 2 mg/ml
injection Aminophylline 25 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Amiodarone hydrochloride 6 mg/ml
NaCl 0,45% Glucose 2,5% 1611
Compatible
injection Fluconazole 2 mg/ml
injection Amoxicillin sodium / clavulanic acid 100/10 mg/ml
3824
Turbidity in one hour Incompatible
injection Fluconazole 2 mg/ml
injection Amphotericin B 5 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Amphotericin B 0.1 mg/ml
None 256
Immediate precipitation Incompatible
injection Fluconazole 2 mg/ml
injection Amphotericin B cholesteryl sulfate complex 0.83 mg/ml
Glucose 5% 921
Compatible
injection Fluconazole 2 mg/ml
Parenteral nutrition (with lipids) 3967
Immediate turbidity Incompatible
injection Fluconazole 2 mg/ml
injection Ampicillin sodium 20 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Ampicillin sodium - sulbactam sodium 60 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Anidulafungin 0.5 mg/ml
Glucose 5% 1982
Compatible
injection Fluconazole 2 mg/ml
injection Aztreonam 40 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Aztreonam 40 mg/ml
Glucose 5% 99
Compatible
injection Fluconazole 2 mg/ml
injection Benztropine mesylate 1 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Bivalirudin 5 mg/ml
Glucose 5% 1713
Compatible
injection Fluconazole 2 mg/ml
injection Caffeine 10 mg/ml
4837
Compatible
injection Fluconazole 2 mg/ml
injection Caffeine 10 mg/ml
None 3964
Compatible
injection Fluconazole 2 mg/ml
injection Caffeine citrate 20 mg/ml
4837
Compatible
injection Fluconazole 2 mg/ml
Parenteral nutrition (with lipids) 1415
Immediate turbidity Incompatible
injection Fluconazole 2 mg/ml
injection Calcium gluconate 100 mg/ml
Sodium chloride 0,9% 496
Immediate turbidity Incompatible
injection Fluconazole 1 mg/ml
Parenteral nutrition (with lipids) 4440
Compatible
injection Fluconazole 2 mg/ml
injection Caspofungin acetate 0.5 mg/ml
Sodium chloride 0,9% 2233
Compatible
injection Fluconazole 2 mg/ml
injection Cefazolin sodium 40 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Cefepime dihydrochloride 125 mg/ml
Water for Injection 2141
Compatible
injection Fluconazole 2 mg/ml
injection Cefiderocol sulfate tosylate 20 mg/mL
Sodium chloride 0,9% 4528
Turbidity in one hour Incompatible
injection Fluconazole 2 mg/ml
injection Cefotaxime sodium 20 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Cefoxitin sodium 40 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Cefpirome sulfate 50 mg/ml
Sodium chloride 0,45% 280
Compatible
injection Fluconazole 2 mg/ml
Ringer’s lactate solution 4603
Compatible
injection Fluconazole 2 mg/ml
injection Cefazolin sodium 20 mg/ml
None 256
Compatible
injection Fluconazole 2 mg/ml
injection Cefpirome sulfate 50 mg/ml
Ringer’s lactate solution 280
Compatible
injection Fluconazole 2 mg/ml
injection Cefpirome sulfate 50 mg/ml
NaCl 0,9% or Glucose 5% 280
Compatible
injection Fluconazole 2 mg/ml
injection Ceftaroline fosamil 2,22 mg/ml
NaCl 0,9% or Glucose 5% 3249
Compatible
injection Fluconazole 2 mg/ml
injection Ceftaroline fosamil 2,22 mg/ml
Ringer’s lactate solution 3249
Color change Incompatible
injection Fluconazole 2 mg/ml
injection Ceftazidime 40 mg/ml
None 256
Compatible
injection Fluconazole 2 mg/ml
injection Ceftazidime 83.3 mg/ml
1759
Compatible
injection Fluconazole
injection Ceftazidime
3883
Immediate precipitation Incompatible
injection Fluconazole 2 mg/ml
injection Ceftazidime 20 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Ceftobiprole medocaril sodium 2 mg/ml
NaCl 0,9% or Glucose 5% 2269
Compatible
injection Fluconazole 2 mg/ml
injection Ceftobiprole medocaril sodium 2 mg/ml
Ringer’s lactate solution 2269
Immediate precipitation Incompatible
injection Fluconazole 2 mg/ml
injection Ceftriaxone disodium 40 mg/ml
Sodium chloride 0,9% 496
Unspecified incompatibility Incompatible
injection Fluconazole
injection Ceftriaxone disodium
3523
Compatible
injection Fluconazole
Parenteral nutrition (binary mixture) 3985
Compatible
injection Fluconazole 2 mg/ml
injection Ceftazidime 125 mg/ml
Water for Injection 2141
Compatible
injection Fluconazole 0.5 & 1.75 mg/ml
Parenteral nutrition (binary mixture) 286
Immediate precipitation Incompatible
injection Fluconazole 2 mg/ml
injection Cefuroxime sodium 30 mg/ml
Sodium chloride 0,9% 496
Production of gas bubbles Incompatible
injection Fluconazole 2 mg/ml
injection Chloramphenicol sodium succinate 20 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Chlorpromazine hydrochloride 25 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Cimetidine hydrochloride 150 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Cimetidine hydrochloride 1 & 2 mg/ml
NaCl 0,9% or Glucose 5% 255
Compatible
injection Fluconazole 2 mg/ml
injection Cisatracurium besylate 0.1 >> 5 mg/ml
Glucose 5% 299
Compatible
injection Fluconazole 2 mg/ml
injection Clindamycin phosphate 12 mg/ml
None 256
Immediate precipitation Incompatible
injection Fluconazole 2 mg/ml
injection Clindamycin phosphate 24 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Cloxacillin sodium 100 mg/ml
Water for Injection 3012
Compatible
injection Fluconazole
injection Daptomycin
2271
Compatible
injection Fluconazole 2 mg/ml
Parenteral nutrition (binary mixture) 3379
Immediate precipitation Incompatible
injection Fluconazole 2 mg/ml
injection Co-trimoxazole 16 mg/ml
Sodium chloride 0,9% 496
Immediate precipitation Incompatible
injection Fluconazole 2 mg/ml
injection Co-trimoxazole 0.8/4 mg/ml
None 256
Compatible
injection Fluconazole 2 mg/ml
Parenteral nutrition (binary mixture) 301
Compatible
injection Fluconazole 1 mg/ml
injection Ciprofloxacin lactate 2 mg/ml
Glucose 5% 285
Compatible
injection Fluconazole 1,3 mg/ml
injection Daptomycin 6,3 mg/ml
Sodium chloride 0,9% 1937
Compatible
injection Fluconazole
injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
Sodium chloride 0,9% 4654
Compatible
injection Fluconazole 2 mg/ml
injection Defibrotide 8 mg/ml
Sodium chloride 0,9% 3728
Compatible
injection Fluconazole 2 mg/ml
injection Dexamethasone sodium phosphate 4 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Dexmedetomidine 4 µg/ml
Sodium chloride 0,9% 1712
Immediate precipitation Incompatible
injection Fluconazole 2 mg/ml
injection Diazepam 5 mg/ml
Sodium chloride 0,9% 496
Production of gas bubbles Incompatible
injection Fluconazole 2 mg/ml
injection Digoxin 250 µg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Diltiazem hydrochloride 5 mg/ml
Sodium chloride 0,9% 198
Compatible
injection Fluconazole
injection Dimenhydrinate
2087
Compatible
injection Fluconazole 2 mg/ml
injection Diphenhydramine hydrochloride 50 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Dobutamine hydrochloride 2 mg/ml
Glucose 5% 255
Compatible
injection Fluconazole 2 mg/ml
injection Docetaxel 0.9 mg/ml
Glucose 5% 1754
Compatible
injection Fluconazole 2 mg/ml
injection Dopamine hydrochloride 1,6 mg/ml
Glucose 5% 255
Compatible
injection Fluconazole 2 mg/ml
injection Doripenem 5 mg/ml
NaCl 0,9% or Glucose 5% 2262
Compatible
injection Fluconazole 2 mg/ml
injection Doxorubicin hydrochloride liposome peg 0.4 mg/ml
Glucose 5% 251
Compatible
injection Fluconazole 2 mg/ml
injection Droperidol 2.5 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Eravacycline 0,6 mg/ml
Sodium chloride 0,9% 4434
Immediate precipitation Incompatible
injection Fluconazole 2 mg/ml
injection Erythromycin lactobionate 20 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Etoposide phosphate 5 mg/ml
Glucose 5% 1410
Compatible
injection Fluconazole 2 mg/ml
injection Famotidine 10 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Famotidine 2 mg/ml
Sodium chloride 0,9% 215
Compatible
injection Fluconazole 2 mg/ml
injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Compatible
injection Fluconazole 2 mg/ml
injection Filgrastim 40 µg/ml
Glucose 5% 104
Compatible
injection Fluconazole 2 mg/ml
injection Filgrastim 30 µg/ml
Glucose 5% 244
Compatible
injection Fluconazole 2 mg/ml
injection Fludarabine phosphate 1 mg/ml
Glucose 5% 492
Compatible
injection Fluconazole 2 mg/ml
injection Folinate calcium 10 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Foscarnet sodium 24 mg/ml
Sodium chloride 0,9% 496
Precipitation after 1 hour Incompatible
injection Fluconazole 2 mg/ml
injection Furosemide 10 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Gallium nitrate 1 mg/ml
Sodium chloride 0,9% 91
Compatible
injection Fluconazole 2 mg/ml
injection Ganciclovir sodium 50 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Gemcitabine hydrochloride 10 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Fluconazole 2 mg/ml
injection Gentamicin sulfate 1 mg/ml
None 256
Compatible
injection Fluconazole 2 mg/ml
injection Gentamicin sulfate 4 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Granisetron hydrochloride 0.05 mg/ml
Glucose 5% 182
Precipitation after 1 hour Incompatible
injection Fluconazole 2 mg/ml
injection Haloperidol lactate 5 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Heparin sodium 50 UI/ml
None 317
Compatible
injection Fluconazole 2 mg/ml
injection Heparin sodium 1000 UI/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Hetastarch 60 mg/ml
specific solvent 1721
Immediate turbidity Incompatible
injection Fluconazole 2 mg/ml
injection Hydroxyzine dihydrochloride 50 mg/ml
Sodium chloride 0,9% 496
Immediate precipitation Incompatible
injection Fluconazole 2 mg/ml
injection Imipenem - cilastatin sodium 10 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Lansoprazole 0.55 mg/ml
Sodium chloride 0,9% 1625
Compatible
injection Fluconazole 2 mg/ml
injection Linezolid 2 mg/ml
None 1925
Compatible
injection Fluconazole 2 mg/ml
injection Lorazepam 0.33 mg/ml
Sodium chloride 0,9% 186
Compatible
injection Fluconazole 2 mg/ml
injection Melphalan 0.1 mg/ml
Sodium chloride 0,9% 169
Compatible
injection Fluconazole 2 mg/ml
injection Meropenem 50 mg/ml
Water for Injection 4319
Compatible
injection Fluconazole 2 mg/ml
injection Meropenem 1 >> 50 mg/ml
Sodium chloride 0,9% 266
Compatible
injection Fluconazole 2 mg/ml
injection Metoclopramide hydrochloride 5 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Metronidazole 5 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Metronidazole 5 mg/ml
None 256
Compatible
injection Fluconazole 2 mg/ml
injection Midazolam hydrochloride 5 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Midazolam hydrochloride 5 mg/ml
None 186
Compatible
injection Fluconazole 2 mg/ml
injection Morphine hydrochloride 0,2 mg/ml
Sodium chloride 0,9% 4831
Compatible
injection Fluconazole 2 mg/ml
injection Morphine sulfate 25 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 1 mg/ml
injection Morphine sulfate 1 mg/ml
Glucose 5% 62
Compatible
injection Fluconazole 2 mg/ml
injection N-acetylcysteine 200 mg/ml
None 3766
Compatible
injection Fluconazole 2 mg/ml
injection Nafcillin sodium 20 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Naloxone hydrochloride 0.4 mg/ml
None 3408
Compatible
injection Fluconazole 2 mg/ml
injection Nitroglycerin 0,2 mg/ml
Glucose 5% 255
Compatible
injection Fluconazole 2 mg/ml
injection Ondansetron hydrochloride 1 mg/ml
Sodium chloride 0,9% 334
Compatible
injection Fluconazole 2 mg/ml
injection Oritavancin 0.8 >>2 mg/ml
Glucose 5% 3152
Compatible
injection Fluconazole 2 mg/ml
injection Oxacillin sodium 40 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Paclitaxel 1.2 mg/ml
Glucose 5% 248
Compatible
injection Fluconazole 2 mg/ml
injection Paclitaxel 0,3 & 1,2 mg/ml
Glucose 5% 151
Compatible
injection Fluconazole 2 mg/ml
injection Pancuronium bromide 0,5 mg/ml
Sodium chloride 0,9% 255
Precipitation after 4 hours Incompatible
injection Fluconazole
injection Pantoprazole sodium
2090
Compatible
injection Fluconazole 2 mg/ml
injection Paracetamol 10 mg/ml
4742
Compatible
injection Fluconazole 2 mg/ml
injection Pemetrexed disodium 20 mg/ml
Sodium chloride 0,9% 1953
Compatible
injection Fluconazole 2 mg/ml
injection Penicillin G potassium 0.1 MUI/ml
Sodium chloride 0,9% 496
Immediate turbidity Incompatible
injection Fluconazole 2 mg/ml
injection Pentamidine isetionate 6 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 1 mg/ml
injection Pethidine hydrochloride 10 mg/ml
Glucose 5% 62
Compatible
injection Fluconazole 2 mg/ml
injection Phenytoin sodium 50 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 1 mg/ml
injection Phloroglucinol 2,5 mg/ml
3791
Compatible
injection Fluconazole 2 mg/ml
injection Piperacillin sodium 80 mg/ml
None 256
Immediate precipitation Incompatible
injection Fluconazole 2 mg/ml
injection Piperacillin sodium 80 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Piperacillin sodium / tazobactam 40/5 mg/ml
Glucose 5% 81
Compatible
injection Fluconazole 2 mg/ml
injection Plazomicin sulfate 24 mg/ml
Sodium chloride 0,9% 4145
Compatible
injection Fluconazole 2 mg/ml
injection Prochlorperazine edysilate 5 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Promethazine hydrochloride 50 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Propofol 10 mg/ml
None 300
Instability of the emulsion after 6 hours Incompatible
injection Fluconazole 2 mg/ml
injection Propofol
660
Compatible
injection Fluconazole 2 mg/ml
injection Quinupristine/dalfopristine 2 mg/ml
Glucose 5% 1513
Compatible
injection Fluconazole 2 mg/ml
injection Ranitidine hydrochloride 0,5 & 2 mg/ml
Glucose 5% 18
Compatible
injection Fluconazole 2 mg/ml
injection Remifentanil hydrochloride 25 & 250 µg/ml
Sodium chloride 0,9% 59
Compatible
injection Fluconazole 2 mg/ml
injection Salbutamol sulfate 1 mg/ml
None 3216
Compatible
injection Fluconazole 2 mg/ml
injection Sargramostim 10 µg/ml
Sodium chloride 0,9% 335
Compatible
injection Fluconazole 1 mg/ml
injection Sodium citrate 40 mg/ml
Sodium chloride 0,9% 3186
Compatible
injection Fluconazole 2 mg/ml
injection Sulbactam/durlobactam 15/15 mg/ml
Sodium chloride 0,9% 4801
Compatible
injection Fluconazole 0,5 & 1,5 mg/ml
injection Tacrolimus 5 & 20 µg/ml
Sodium chloride 0,9% 1421
Compatible
injection Fluconazole 2 mg/ml
injection Tacrolimus 1000 µg/ml
Sodium chloride 0,9% 479
Unspecified incompatibility Incompatible
injection Fluconazole 2 mg/ml
injection Telavancin hydrochloride 7.5 mg/ml
Ringer’s lactate solution 3254
Compatible
injection Fluconazole 2 mg/ml
injection Telavancin hydrochloride 7.5 mg/ml
Sodium chloride 0,9% 3254
Compatible
injection Fluconazole 2 mg/ml
injection Temocilline 83.33 mg/ml
Water for Injection 2231
Compatible
injection Fluconazole 2 mg/ml
injection Teniposide 0.1 mg/ml
Glucose 5% 905
Compatible
injection Fluconazole 2 mg/ml
injection Theophylline 4 mg/ml
None 317
Compatible
injection Fluconazole 2 mg/ml
injection Theophylline 1,6 mg/ml
Glucose 5% 255
Compatible
injection Fluconazole 2 mg/ml
injection Thiamine hydrochloride 0.2 mg/ml
Sodium chloride 0,9% 4254
Immediate precipitation Incompatible
injection Fluconazole 2 mg/ml
injection Thiopental sodium 25 mg/ml
Sodium chloride 0,9% 3767
Compatible
injection Fluconazole 2 mg/ml
injection Thiotepa 1 mg/ml
Glucose 5% 249
Compatible
injection Fluconazole 2 mg/ml
injection Ticarcillin / clavulanic acid 60 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Tobramycin sulfate 40 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Vancomycin hydrochloride 20 mg/ml
Sodium chloride 0,9% 496
Compatible
injection Fluconazole 2 mg/ml
injection Vancomycin hydrochloride 10 mg/ml
Glucose 5% 3385
Compatible
injection Fluconazole 2 mg/ml
injection Vasopressin 0.2 UI/ml
Sodium chloride 0,9% 2017
Compatible
injection Fluconazole 2 mg/ml
injection Vecuronium bromide 1 mg/ml
Glucose 5% 255
Compatible
injection Fluconazole 2 mg/ml
injection Vinorelbine tartrate 1 mg/ml
Sodium chloride 0,9% 84
Compatible
injection Fluconazole 2 mg/ml
injection Zidovudine 10 mg/ml
Sodium chloride 0,9% 496

  Mentions Légales