Last update :
09/04/2024
Anticancer drug   Melphalan  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Alkeran Australia, Austria, Belgium, Brazil, Canada, Chile, Colombia, France, Germany, Great Britain, Greece, Ireland, Italy, Luxembourg, Malaysia, New Zealand, Sweden, Switzerland, United Arab Emirates, United States of America
Egymelan Peru
Eriolan Argentina, Ecuador
Melfalan Argentina, Chile, Ecuador, Germany, Spain
Melfoma Argentina, Peru
Compatibility   Injection   Compatibility : Melphalan              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
Injection Melphalan 0.1 mg/ml
Injection Aciclovir sodium 7 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Allopurinol sodium 3 mg/ml
Sodium chloride 0,9% 307
Compatible
Injection Melphalan 0.1 mg/ml
Injection Amikacin sulfate 5 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Aminophylline 2.5 mg/ml
Sodium chloride 0,9% 169
Immediate turbidity Incompatible
Injection Melphalan 0.1 mg/ml
Injection Amphotericin B 0.6 mg/ml
Sodium chloride 0,9% 169
Chemical instability Incompatible
Injection Melphalan 0.1 mg/ml
Injection Amphotericin B 0.6 mg/ml
Glucose 5% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Ampicillin sodium 20 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Aztreonam 40 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Bleomycin sulfate 1 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Bumetanide 0.04 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Buprenorphine hydrochloride 0.04 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Butorphanol tartrate 0.04 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Calcium gluconate 40 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Carboplatin 5 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Carmustine 1.5 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 1 mg/ml
Injection Caspofungin acetate 0,7 mg/ml
Sodium chloride 0,9% 2247
Chemical instability Incompatible
Injection Melphalan
Glucose 5% 3584
Compatible
Injection Melphalan 0.1 mg/ml
Injection Cefazolin sodium 20 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Cefoperazone sodium 40 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Ceforanide 20 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Cefotaxime sodium 20 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Ceftazidime 40 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Ceftizoxime sodium 20 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Ceftriaxone disodium 20 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Cefuroxime sodium 20 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Chlormethine hydrochloride 1 mg/ml
Sodium chloride 0,9% 307
Turbidity in one hour Incompatible
Injection Melphalan 0.1 mg/ml
Injection Chlorpromazine hydrochloride 2 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Cimetidine hydrochloride 12 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Cisplatin 1 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Clindamycin phosphate 10 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Co-trimoxazole 0.8/4 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Cyclophosphamide 10 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Cytarabine 50 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Dacarbazine 4 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Dactinomycin 10 µg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Daunorubicin hydrochloride 1 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Dexamethasone sodium phosphate 1 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Diphenhydramine hydrochloride 2 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Doxorubicin hydrochloride 2 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Doxycycline hyclate 1 mg/ml
Sodium chloride 0,9% 307
Compatible
Injection Melphalan 0.1 mg/ml
Injection Droperidol 0.4 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Enalaprilate 0.1 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Etoposide 0.4 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Famotidine 2 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Filgrastim 30 µg/ml
Glucose 5% 244
Compatible
Injection Melphalan 0.1 mg/ml
Injection Floxuridine 3 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Fluconazole 2 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Fludarabine phosphate 1 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Fluorouracil 16 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Furosemide 3 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Gallium nitrate 0.4 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Ganciclovir sodium 20 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Gentamicin sulfate 5 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Granisetron hydrochloride 0.05 mg/ml
Sodium chloride 0,9% 182
Compatible
Injection Melphalan 0.1 mg/ml
Injection Haloperidol lactate 0.2 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Heparin sodium 100 UI/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Hydrocortisone sodium succinate 1 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Hydromorphone hydrochloride 0.5 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Hydroxyzine dihydrochloride 4 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Idarubicin hydrochloride 0.5 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Ifosfamide 25 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Imipenem - cilastatin sodium 10 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan
Injection Iohexol
Sodium chloride 0,9% 4376
Compatible
Injection Melphalan
Injection Ioversol
Sodium chloride 0,9% 4376
Compatible
Injection Melphalan 0.1 mg/ml
Injection Lorazepam 0.1 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Mannitol 150 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Mesna 10 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Methotrexate sodium 15 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Methylprednisolone sodium succinate 5 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Metoclopramide hydrochloride 5 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Metronidazole 5 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Minocycline hydrochloride 0.2 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Mitomycin 0.5 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Mitoxantrone dihydrochloride 0.5 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Morphine sulfate 1 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Nalbuphine hydrochloride 10 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Netilmicin sulfate 5 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Ondansetron hydrochloride 1 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Pentostatin 0.4 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Pethidine hydrochloride 4 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Piperacillin sodium 40 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Potassium chloride 100 mEq/l
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Prochlorperazine edysilate 0.5 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Promethazine hydrochloride 2 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Ranitidine hydrochloride 2 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Sodium bicarbonate 84 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Streptozocin 40 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Teniposide 0.1 mg/ml
Glucose 5% 905
Compatible
Injection Melphalan 0.1 mg/ml
Injection Thiotepa 10 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Ticarcillin / clavulanic acid 31 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Tobramycin sulfate 5 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Vancomycin hydrochloride 10 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Vinblastine sulfate 0.12 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Vincristine sulfate 0.05 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Melphalan 0.1 mg/ml
Injection Vinorelbine tartrate 1 mg/ml
Sodium chloride 0,9% 84
Compatible
Injection Melphalan 0.1 mg/ml
Injection Zidovudine 4 mg/ml
Sodium chloride 0,9% 169

  Mentions Légales