Last update :
01/10/2024
Anticancer drug   Thiotepa  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Bedford New Zealand
Ledertepa Netherlands
Oncotiotepa Spain
Thioplex Italy
Thiotepa Australia, Austria, Germany, Great Britain, Ireland, Sweden, United States of America
Stability in solutions   injection   Stability in solutions : Thiotepa     
Container Solvent Concentration Temperature Storage Duration of stability References
Glass Water for Injection 10 mg/ml 2-8°C Not specified
8 Hour
3603
Manufacturer's stability data

Glass Water for Injection 10 mg/ml 2-8°C Not specified
14 Day
4748
Level of evidence A+

Glass Water for Injection 10 mg/ml 25°C Light
1 Day
4748
Level of evidence A+

Polyvinyl chloride Sodium chloride 0,9% 1 & 3 mg/ml 25°C Light
24 Hour
302
Level of evidence B+

Polyvinyl chloride Sodium chloride 0,9% 1 & 3 mg/ml 8°C Light
48 Hour
302
Level of evidence B+

Polyolefine NaCl 0,9% or Glucose 5% 1 & 2 & 3 mg/ml 2-8°C Not specified
14 Day
4748
Level of evidence A+

Polyolefine Sodium chloride 0,9% 1 & 2 & 3 mg/ml 25°C Light
1 Day
4748
Level of evidence A+

Polyolefine Glucose 5% 1 mg/ml 2-8°C Protect from light
14 Day
4677
Level of evidence C+

Polyolefine Glucose 5% 1 mg/ml 25°C Light
3 Day
4677
Level of evidence C+

Polyolefine Glucose 5% 1 mg/ml 25°C Light
3 Day
4748
Level of evidence A+

Polyolefine Glucose 5% 2 mg/ml 2-8°C Protect from light
14 Day
4677
Level of evidence C+

Polyolefine Glucose 5% 2 mg/ml 25°C Light
5 Day
4748
Level of evidence A+

Polyolefine Glucose 5% 3 mg/ml 2-8°C Protect from light
14 Day
4677
Level of evidence C+

Polyolefine Glucose 5% 3 mg/ml 25°C Light
5 Day
4677
Level of evidence C+

Polyolefine Glucose 5% 3 mg/ml 25°C Light
7 Day
4748
Level of evidence A+

Not specified Sodium chloride 0,9% 0.5 & 1 mg/ml 2-8°C Not specified
24 Hour
3603
Manufacturer's stability data

Not specified Sodium chloride 0,9% 0.5 & 1 mg/ml 25°C Not specified
4 Hour
3603
Manufacturer's stability data


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