Last update :
17/04/2024
Antibiotic   Cefepime dihydrochloride  
Injection
Eye-drops
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Aspime Venezuela
Avipim Turkey
Axépim France
Baxypime Mexico
Cachepime India
Cefalospim Brazil
Cefemin Colombia
Cefepem Brazil
Cefepitax Brazil
Cepim Italy
Cepimex Italy
Forcetex Egypt
Maxcef Brazil
Maxipime Austria, Belgium, Canada, Colombia, Finland, Germany, Greece, Hungary, Italy, Luxembourg, Peru, Poland, Portugal, Spain, Sweden, Turkey, United States of America
Nebamix Peru
Olpelinol Mexico
Pimcef Peru
Pimerzen Mexico
Roxipime Turkey
Unisef Turkey
Vipefime Mexico
Stability in solutions   Injection   Stability in solutions : Cefepime dihydrochloride     
Container Solvent Concentration Temperature Storage Duration of stability References
Polyvinyl chloride NaCl 0,9% or Glucose 5% 2,5/5/10/20 mg/ml 4°C Light
7 Day
1605
Level of evidence B

Polyvinyl chloride NaCl 0,9% or Glucose 5% 20 mg/ml 22°C-24°C Light
3 Day
1605
Level of evidence B

Polyvinyl chloride NaCl 0,9% or Glucose 5% 20 mg/ml 25°C Not specified
2 Day
873
Level of evidence D

Polyvinyl chloride NaCl 0,9% or Glucose 5% 20 mg/ml 5°C Protect from light
23 Day
873
Level of evidence D

Polyvinyl chloride Sodium chloride 0,9% 10 mg/ml 22°C-24°C Light
1 Day
1605
Level of evidence B

Polyvinyl chloride Sodium chloride 0,9% 2,5 mg/ml 22°C-24°C Light
6 Day
1605
Level of evidence B

Polyvinyl chloride Sodium chloride 0,9% 5 mg/ml 22°C-24°C Light
3 Day
1605
Level of evidence B

Polyvinyl chloride Glucose 5% 10 mg/ml 22°C-24°C Light
2 Day
1605
Level of evidence B

Polyvinyl chloride Glucose 5% 2,5 mg/ml 22°C-24°C Light
4 Day
1605
Level of evidence B

Polyvinyl chloride Glucose 5% 20 mg/ml -20°C Protect from light
30 Day
1648
Level of evidence B

Polyvinyl chloride Glucose 5% 20 mg/ml 4°C Protect from light
11 Day
1648
Level of evidence B

Polyvinyl chloride Glucose 5% 5 mg/ml 22°C-24°C Light
1 Day
1605
Level of evidence B

Polyvinyl chloride Extraneal® (Baxter) 0,5 mg/ml 37°C Not specified
4 Hour
1945
Level of evidence D

Polyvinyl chloride Extraneal® (Baxter) 0,5 mg/ml 4°C Not specified
7 Day
1945
Level of evidence D

Polyethylene NaCl 0,9% or Glucose 5% 8 mg/ml 24°C Light
48 Hour
1673
Level of evidence B

Polyethylene NaCl 0,9% or Glucose 5% 8 mg/ml 4°C Protect from light
15 Day
1673
Level of evidence B

Ethylene vinyl acetate Sodium chloride 0,9% 10 mg/ml 23°C Protect from light
2 Day
1834
Level of evidence B+

Ethylene vinyl acetate Sodium chloride 0,9% 10 mg/ml 4°C Protect from light
30 Day
1834
Level of evidence B+

Ethylene vinyl acetate Sodium chloride 0,9% 40 mg/ml 23°C Protect from light
1 Day
1834
Level of evidence B+

Ethylene vinyl acetate Sodium chloride 0,9% 40 mg/ml 4°C Protect from light
7 Day
1834
Level of evidence B+

Ethylene vinyl acetate Glucose 5% 2,9 mg/ml -20°C Protect from light
14 Day
2046
Level of evidence C

Ethylene vinyl acetate Glucose 5% 2,9 mg/ml 25°C Protect from light
24 Hour
2046
Level of evidence C

Ethylene vinyl acetate Glucose 5% 2,9 mg/ml 4°C Protect from light
7 Day
2046
Level of evidence C

Polypropylen Syringe Water for Injection 100 & 200 mg/ml -20°C Protect from light
90 Day
1068
Level of evidence B

Polypropylen Syringe Water for Injection 100 & 200 mg/ml 22-24°C Not specified
2 Day
1046
Level of evidence B

Polypropylen Syringe Water for Injection 100 & 200 mg/ml 4°C Protect from light
7 Day
1068
Level of evidence B

Polypropylen Syringe Water for Injection 100 & 200 mg/ml 4°C Protect from light
14 Day
1046
Level of evidence B

Polypropylen Syringe NaCl 0,9% or Glucose 5% 100 & 200 mg/ml -20°C Protect from light
90 Day
1068
Level of evidence B

Polypropylen Syringe NaCl 0,9% or Glucose 5% 100 & 200 mg/ml 4°C Protect from light
7 Day
1068
Level of evidence B

Polypropylen Syringe NaCl 0,9% or Glucose 5% 125 mg/ml 20-25°C Light
24 Hour
4634
Level of evidence C+

Polypropylen Syringe NaCl 0,9% or Glucose 5% 200 mg/ml 22-24°C Not specified
2 Day
1046
Level of evidence B

Polypropylen Syringe NaCl 0,9% or Glucose 5% 200 mg/ml 4°C Protect from light
14 Day
1046
Level of evidence B

Polypropylen Syringe Sodium chloride 0,9% 100 mg/ml 22°C-24°C Not specified
2 Day
1046
Level of evidence B

Polypropylen Syringe Sodium chloride 0,9% 120 mg/ml 25°C Light
10 Hour
4326
Level of evidence B

Polypropylen Syringe Sodium chloride 0,9% 20 mg/ml 25°C Not specified
2 Day
1626
Level of evidence A

Polypropylen Syringe Sodium chloride 0,9% 20 mg/ml 25°C Light
12 Hour
4326
Level of evidence B

Polypropylen Syringe Sodium chloride 0,9% 20 mg/ml 5°C Not specified
21 Day
1626
Level of evidence A

Polypropylen Syringe Sodium chloride 0,9% 40 mg/ml 25°C Light
10 Hour
4326
Level of evidence B

Polypropylen Syringe Glucose 5% 100 mg/ml 22°C-24°C Not specified
1 Day
1046
Level of evidence B

Elastomer (unspecified) Water for Injection 50 mg/ml 25°C Not specified
20 Hour
2042
Level of evidence D

Elastomer (unspecified) Water for Injection 50 mg/ml 37°C Not specified
13 Hour
2042
Level of evidence D

Not specified Deflex® PD 1.5% glucose (Fresenius) 0,1 mg/ml 25°C
7 Day
1290
Level of evidence D

Not specified Deflex® PD 1.5% glucose (Fresenius) 0,1 mg/ml 37°C
48 Hour
1290
Level of evidence D

Not specified Deflex® PD 1.5% glucose (Fresenius) 0,1 mg/ml 4°C Protect from light
14 Day
1290
Level of evidence D


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