Last update :
07/10/2024
Antibiotic   Piperacillin sodium  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Avocin Italy
Cilpier Italy
Diperil Italy
Ecosette Italy
Farecillin Italy
Ivacin Denmark
Pentcillin Japan
Peracil Italy
Pipcil Netherlands
Pipera Germany
Piperacillin Australia, Canada, Germany, Poland, United States of America
Piperacilline France, Greece, Tunisia
Piperital Italy
Pipertex Italy
Pipracil Egypt
Pipril Colombia, Denmark, Greece, United Arab Emirates
Semipenil Italy
Stability in solutions   injection   Stability in solutions : Piperacillin sodium     
Container Solvent Concentration Temperature Storage Duration of stability References
Glass NaCl 0,9% or Glucose 5% 40 mg/ml 25°C Light
48 Hour
432
Level of evidence D

Polyvinyl chloride NaCl 0,9% or Glucose 5% 10 mg/ml -10°C Protect from light
71 Day
600
Level of evidence B

Polyvinyl chloride NaCl 0,9% or Glucose 5% 10 mg/ml 25°C Not specified
120 Hour
600
Level of evidence B

Polyvinyl chloride NaCl 0,9% or Glucose 5% 10 mg/ml 5°C Protect from light
49 Day
600
Level of evidence B

Polyvinyl chloride Sodium chloride 0,9% 80 mg/ml -20°C Protect from light
100 Day
1329
Level of evidence B

Polypropylene Sodium chloride 0,9% 20 mg/ml 2-8°C Protect from light
28 Day
1845
Level of evidence B+

Polypropylene Sodium chloride 0,9% 20 mg/ml 25°C Protect from light
7 Day
1845
Level of evidence B+

Ethylene vinyl acetate Sodium chloride 0,9% 30 & 40 mg/ml 23°C Protect from light
5 Day
1826
Level of evidence B+

Ethylene vinyl acetate Sodium chloride 0,9% 30 & 40 mg/ml 4°C Protect from light
21 Day
1826
Level of evidence B+

Polypropylen Syringe Sodium chloride 0,9% 125 mg/ml 20-25°C Light
24 Hour
4634
Level of evidence C+

Polypropylen Syringe Sodium chloride 0,9% 40 mg/ml 25°C Not specified
5 Day
1718
Level of evidence B

Polypropylen Syringe Sodium chloride 0,9% 40 mg/ml 5°C Protect from light
28 Day
1718
Level of evidence B

Polypropylen Syringe Glucose 5% 125 mg/ml 20-25°C Light
48 Hour
4634
Level of evidence C+

Polyisoprene elastomer NaCl 0,9% or Glucose 5% 10 & 80 mg/ml 25°C Not specified
24 Hour
604
Manufacturer's stability data

Polyisoprene elastomer NaCl 0,9% or Glucose 5% 10 & 80 mg/ml 4°C Protect from light
14 Day
604
Manufacturer's stability data

Elastomer (unspecified) Water for Injection 128 mg/ml 25°C Not specified
30 Hour
2042
Level of evidence D

Elastomer (unspecified) Water for Injection 128 mg/ml 37°C Not specified
21 Hour
2042
Level of evidence D


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