Last update :
18/04/2024
Anticancer drug   Thiotepa  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Bedford New Zealand
Ledertepa Netherlands
Oncotiotepa Spain
Thioplex Italy
Thiotepa Australia, Austria, Germany, Great Britain, Ireland, Sweden, United States of America
Compatibility   Injection   Compatibility : Thiotepa              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
Injection Thiotepa 1 mg/ml
Parenteral nutrition (binary mixture) 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Aciclovir sodium 7 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Allopurinol sodium 3 mg/ml
Sodium chloride 0,9% 307
Compatible
Injection Thiotepa 1 mg/ml
Injection Amifostine 10 mg/ml
Glucose 5% 3
Compatible
Injection Thiotepa 1 mg/ml
Injection Amikacin sulfate 5 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Aminophylline 2.5 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Amphotericin B 0.6 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Ampicillin sodium 20 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Ampicillin sodium - sulbactam sodium 20/10 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Aztreonam 40 mg/ml
Glucose 5% 99
Compatible
Injection Thiotepa 1 mg/ml
Injection Aztreonam 40 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Bleomycin sulfate 1 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Bumetanide 0.04 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Buprenorphine hydrochloride 0.04 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Butorphanol tartrate 0.04 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Calcium gluconate 40 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Carboplatin 5 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Carmustine 1.5 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Cefazolin sodium 20 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Cefonicid sodium 20 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Cefoperazone sodium 40 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Cefotaxime sodium 20 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Cefoxitin sodium 20 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Ceftazidime 40 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Ceftizoxime sodium 20 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Ceftriaxone disodium 20 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Cefuroxime sodium 30 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Chlorpromazine hydrochloride 2 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Cimetidine hydrochloride 12 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Ciprofloxacin lactate 1 mg/ml
Glucose 5% 249
Turbidity in 4 hours Incompatible
Injection Thiotepa 1 mg/ml
Injection Cisplatin 1 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Clindamycin phosphate 10 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Co-trimoxazole 0.8/4 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Cyclophosphamide 10 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Cytarabine 50 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Dacarbazine 4 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Dactinomycin 10 µg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Daunorubicin hydrochloride 1 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Dexamethasone sodium phosphate 1 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Diphenhydramine hydrochloride 2 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Dobutamine hydrochloride 4 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Dopamine hydrochloride 3.2 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Doxorubicin hydrochloride 2 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Doxycycline hyclate 1 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Droperidol 0.4 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Enalaprilate 0.1 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Etoposide 0.4 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Etoposide phosphate 5 mg/ml
Glucose 5% 1410
Compatible
Injection Thiotepa 1 mg/ml
Injection Famotidine 2 mg/ml
Glucose 5% 249
Immediate precipitation Incompatible
Injection Thiotepa 1 mg/ml
Injection Filgrastim 30 µg/ml
Glucose 5% 244
Compatible
Injection Thiotepa 1 mg/ml
Injection Floxuridine 3 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Fluconazole 2 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Fludarabine phosphate 1 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Fluorouracil 16 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Folinate calcium 2 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Furosemide 3 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Gallium nitrate 0.4 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Ganciclovir sodium 20 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Gemcitabine hydrochloride 10 mg/ml
Sodium chloride 0,9% 1423
Compatible
Injection Thiotepa 1 mg/ml
Injection Gentamicin sulfate 5 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Granisetron hydrochloride 0.05 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Granisetron hydrochloride 0.05 mg/ml
Glucose 5% 182
Compatible
Injection Thiotepa 1 mg/ml
Injection Haloperidol lactate 0.2 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Heparin sodium 100 UI/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Hydrocortisone sodium succinate 1 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Hydromorphone hydrochloride 0.5 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Hydroxyzine dihydrochloride 4 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Idarubicin hydrochloride 0.5 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Ifosfamide 25 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Imipenem - cilastatin sodium 10 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Lorazepam 0.1 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Magnesium sulfate 100 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Mannitol 150 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 10 mg/ml
Injection Melphalan 0.1 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Thiotepa 1 mg/ml
Injection Mesna 10 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Methotrexate sodium 15 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Methylprednisolone sodium succinate 5 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Metoclopramide hydrochloride 5 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Metronidazole 5 mg/ml
Glucose 5% 249
Color change after 1 hour Incompatible
Injection Thiotepa 1 mg/ml
Injection Minocycline hydrochloride 0.2 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Mitomycin 0.5 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Mitoxantrone dihydrochloride 0.5 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Morphine sulfate 1 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Nalbuphine hydrochloride 10 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Netilmicin sulfate 5 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Ofloxacin 4 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Ondansetron hydrochloride 1 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Paclitaxel 0.6 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Pethidine hydrochloride 4 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Piperacillin sodium 40 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Piperacillin sodium / tazobactam 40/5 mg/ml
Glucose 5% 81
Compatible
Injection Thiotepa 1 mg/ml
Injection Potassium chloride 100 mEq/l
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Prochlorperazine edysilate 0.5 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Promethazine hydrochloride 2 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Ranitidine hydrochloride 20 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Sodium bicarbonate 84 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Streptozocin 40 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Teniposide 0.1 mg/ml
Glucose 5% 905
Compatible
Injection Thiotepa 1 mg/ml
Injection Ticarcillin / clavulanic acid 31 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Tobramycin sulfate 5 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Vancomycin hydrochloride 10 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Vinblastine sulfate 0.12 mg/ml
Glucose 5% 249
Compatible
Injection Thiotepa 1 mg/ml
Injection Vincristine sulfate 0.05 mg/ml
Glucose 5% 249
Immediate precipitation Incompatible
Injection Thiotepa 1 mg/ml
Injection Vinorelbine tartrate 1 mg/ml
Sodium chloride 0,9% 84
Compatible
Injection Thiotepa 1 mg/ml
Injection Zidovudine 4 mg/ml
Glucose 5% 249

  Mentions Légales