Last update :
18/04/2024
Anticancer drug   Idarubicin hydrochloride  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Idacrybin Mexico
Idamen Turkey
Idamycin Canada, Mexico, United States of America
Idaralem Colombia, Mexico
Ondarubin Mexico
Rubix Mexico
Zavedos Argentina, Australia, Austria, Belgium, Chile, Colombia, Croatia, Denmark, Ecuador, Finland, France, Germany, Great Britain, Greece, Hungary, Iceland, Ireland, Italy, Luxembourg, Malaysia, Morocco, Netherlands, New Zealand, Norway, Poland, Portugal, Republic of South Africa, Romania, Russian, Saudi Arabia, Slovenia, Spain, Sweden, Switzerland, Thailand, Venezuela
Compatibility   Injection   Compatibility : Idarubicin hydrochloride              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Unspecified incompatibility Incompatible
Injection Idarubicin hydrochloride
Injection Aciclovir sodium
3595
Immediate turbidity Incompatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Aciclovir sodium 5 mg/ml
Sodium chloride 0,9% 491
Precipitation after 1 hour Incompatible
Injection Idarubicin hydrochloride 0.5 mg/ml
Injection Allopurinol sodium 3 mg/ml
Sodium chloride 0,9% 307
Compatible
Injection Idarubicin hydrochloride 0.5 mg/ml
Injection Amifostine 10 mg/ml
Glucose 5% 3
Compatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Amikacin sulfate 5 mg/ml
Sodium chloride 0,9% 491
Immediate turbidity Incompatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Ampicillin sodium - sulbactam sodium 30 mg/ml
Sodium chloride 0,9% 491
Compatible
Injection Idarubicin hydrochloride 0.5 mg/ml
Injection Aztreonam 40 mg/ml
Glucose 5% 99
Precipitation after 1 hour Incompatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Cefazolin sodium 20 mg/ml
Sodium chloride 0,9% 491
Turbidity in one hour Incompatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Ceftazidime 20 mg/ml
Sodium chloride 0,9% 491
Compatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Cimetidine hydrochloride 6 mg/ml
Sodium chloride 0,9% 491
Compatible
Injection Idarubicin hydrochloride 0.5 mg/ml
Injection Cladribine 0.5 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
Injection Idarubicin hydrochloride 0.5 mg/ml
Injection Cladribine 0.015 mg/ml
Sodium chloride 0,9% 1496
Unspecified incompatibility Incompatible
Injection Idarubicin hydrochloride
Injection Clindamycin phosphate
3526
Immediate precipitation Incompatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Clindamycin phosphate 12 mg/ml
Sodium chloride 0,9% 491
Compatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Cyclophosphamide 4 mg/ml
Sodium chloride 0,9% 491
Compatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Cytarabine 6 mg/ml
Sodium chloride 0,9% 491
Immediate turbidity Incompatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Dexamethasone sodium phosphate 10 mg/ml
Sodium chloride 0,9% 491
Turbidity in one hour Incompatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Dexamethasone sodium phosphate 0.2 mg/ml
Sodium chloride 0,9% 491
Compatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Diphenhydramine hydrochloride 1 & 50 mg/ml
Sodium chloride 0,9% 491
Compatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Droperidol 0.04 & 2.5 mg/ml
Sodium chloride 0,9% 491
Compatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Erythromycin lactobionate 2 mg/ml
Sodium chloride 0,9% 491
Production of gas bubbles Incompatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Etoposide 0.4 mg/ml
Sodium chloride 0,9% 491
Compatible
Injection Idarubicin hydrochloride 0.5 mg/ml
Injection Etoposide phosphate 5 mg/ml
Glucose 5% 1410
Compatible
Injection Idarubicin hydrochloride 0.5 mg/ml
Injection Filgrastim 30 µg/ml
Glucose 5% 244
Unspecified incompatibility Incompatible
Injection Idarubicin hydrochloride
Injection Fluorouracil
3474
Immediate precipitation Incompatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Furosemide 0,8 & 10 mg/ml
Sodium chloride 0,9% 491
Compatible
Injection Idarubicin hydrochloride 0.5 mg/ml
Injection Gemcitabine hydrochloride 10 mg/ml
Sodium chloride 0,9% 1423
Color change Incompatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Gentamicin sulfate 3 mg/ml
Sodium chloride 0,9% 491
Compatible
Injection Idarubicin hydrochloride 0.5 mg/ml
Injection Granisetron hydrochloride 0.05 mg/ml
Glucose 5% 182
Immediate turbidity Incompatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Heparin sodium 100 & 1000 UI/ml
Sodium chloride 0,9% 491
Immediate turbidity Incompatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Hydrocortisone sodium succinate 2 & 50 mg/ml
Sodium chloride 0,9% 491
Precipitation after 24 hours Incompatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Imipenem - cilastatin sodium 5 mg/ml
Sodium chloride 0,9% 491
Color change Incompatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Lorazepam 2 mg/ml
Sodium chloride 0,9% 491
Compatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Mannitol 12.5 mg/ml
Sodium chloride 0,9% 491
Compatible
Injection Idarubicin hydrochloride 1 mg/ml
Parenteral nutrition (binary mixture) 491
Compatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Magnesium sulfate 2 mg/ml
Sodium chloride 0,9% 491
Compatible
Injection Idarubicin hydrochloride 0.5 mg/ml
Injection Melphalan 0.1 mg/ml
Sodium chloride 0,9% 169
Color change Incompatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Methotrexate sodium 25 mg/ml
Sodium chloride 0,9% 491
Unspecified incompatibility Incompatible
Injection Idarubicin hydrochloride
Injection Methotrexate sodium
3637
Compatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Metoclopramide hydrochloride 5 mg/ml
Sodium chloride 0,9% 491
Color change Incompatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Pethidine hydrochloride 1 & 50 mg/ml
Sodium chloride 0,9% 491
Immediate turbidity Incompatible
Injection Idarubicin hydrochloride 0.5 mg/ml
Injection Piperacillin sodium / tazobactam 40/5 mg/ml
Glucose 5% 81
Compatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Potassium chloride 30 mEq/l
Sodium chloride 0,9% 491
Compatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Ranitidine hydrochloride 1 mg/ml
Sodium chloride 0,9% 491
Immediate turbidity Incompatible
Injection Idarubicin hydrochloride 0.5 mg/ml
Injection Sargramostim 10 µg/ml
Sodium chloride 0,9% 335
Immediate turbidity Incompatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Sodium bicarbonate 7.56 mg/ml
Sodium chloride 0,9% 491
Immediate turbidity Incompatible
Injection Idarubicin hydrochloride 0.5 mg/ml
Injection Teniposide 0.1 mg/ml
Glucose 5% 905
Compatible
Injection Idarubicin hydrochloride 0.5 mg/ml
Injection Thiotepa 1 mg/ml
Glucose 5% 249
Color change Incompatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Vancomycin hydrochloride 4 mg/ml
Sodium chloride 0,9% 491
Color change Incompatible
Injection Idarubicin hydrochloride 1 mg/ml
Injection Vincristine sulfate 1 mg/ml
Sodium chloride 0,9% 491
Immediate turbidity Incompatible
Injection Idarubicin hydrochloride 0.5 mg/ml
Injection Vinorelbine tartrate 1 mg/ml
Sodium chloride 0,9% 84
Immediate turbidity Incompatible
Injection Idarubicin hydrochloride
NaHCO3 491

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