Last update :
17/04/2024
Various   Aminophylline  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Aminocardol Turkey
Aminodic Iran
Aminofilina Argentina, Chile, Colombia, Ecuador, Italy, Mexico, Peru, Portugal, Venezuela
Aminomal Italy
Aminophyllin Malaysia, Norway, Switzerland
Aminophylline Australia, Canada, Great Britain, Greece, Iran, Ireland, Malaysia, Saudi Arabia, United States of America
Aminophyllinum Poland
Amipine Malaysia
Amofilin Colombia, Mexico
Broncophilina Venezuela
Diaphyllin Hungary
Drafilyn Mexico
Euphyllin Austria, Luxembourg, Netherlands, Saudi Arabia, Switzerland
Euphyllina Italy
Fadafilina Argentina
Minophyline Egypt
Minotec Mexico
Miofilin Romania
Neophyllin Japan
Tecar Turkey
Tefamin Italy
Teofillina Italy
Teofylamin Denmark
Teofyllamin Sweden
Teolin Iran
Compatibility   Injection   Compatibility : Aminophylline              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Allopurinol sodium 3 mg/ml
Sodium chloride 0,9% 307
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Amifostine 10 mg/ml
Glucose 5% 3
Precipitation after 15 minutes Incompatible
Injection Aminophylline 5 mg/ml
Injection Amiodarone hydrochloride 4 mg/ml
NaCl 0,9% or Glucose 5% 1036
Compatible
Injection Aminophylline 25 mg/ml
Injection Amoxicillin sodium / clavulanic acid 100/10 mg/ml
3824
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Amphotericin B cholesteryl sulfate complex 0.83 mg/ml
Glucose 5% 921
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Anidulafungin 0.5 mg/ml
Glucose 5% 1982
Compatible
Injection Aminophylline 1 mg/ml
Injection Atracurium besylate 0.5 mg/ml
Glucose 5% 402
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Aztreonam 40 mg/ml
Glucose 5% 99
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Bivalirudin 5 mg/ml
Glucose 5% 1713
Unspecified incompatibility Incompatible
Injection Aminophylline
Injection Bleomycin sulfate
4154
Unspecified incompatibility Incompatible
Injection Aminophylline
Injection Bleomycin sulfate
3646
Compatible
Injection Aminophylline 1 mg/ml
Injection Bretylium tosilate 1 mg/ml
NaCl 0,9% or Glucose 5% 1193
Unspecified incompatibility Incompatible
Injection Aminophylline
Injection Cefepime dihydrochloride
3548
Subvisual incompatibility Incompatible
Injection Aminophylline 1 mg/ml
Injection Cefiderocol sulfate tosylate 20 mg/mL
Sodium chloride 0,9% 4528
Compatible
Injection Aminophylline 1 mg/ml
Injection Cefiderocol sulfate tosylate 20 mg/mL
Glucose 5% 4528
Compatible
Injection Aminophylline 2,5 mg/ml
Injection Ceftaroline fosamil 2,22 mg/ml
Ringer’s lactate solution 3249
Compatible
Injection Aminophylline 2,5 mg/ml
Injection Ceftaroline fosamil 2,22 mg/ml
NaCl 0,9% or Glucose 5% 3249
Unspecified incompatibility Incompatible
Injection Aminophylline
Injection Ceftazidime
3543
Chemical instability Incompatible
Injection Aminophylline 1 & 2 mg/ml
Injection Ceftazidime 2 & 6 mg/ml
NaCl 0,9% or Glucose 5% 900
Chemical instability Incompatible
Injection Aminophylline 0.16 mg/ml
Injection Ceftazidime 0.32 mg/ml
Glucose 5% 3696
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Ceftobiprole medocaril sodium 2 mg/ml
NaCl 0,9% or Glucose 5% 2269
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Ceftobiprole medocaril sodium 2 mg/ml
Ringer’s lactate solution 2269
Chemical instability Incompatible
Injection Aminophylline 1 & 4 mg/ml
Injection Ceftriaxone disodium 20 & 40 mg/ml
NaCl 0,9% or Glucose 5% 276
Compatible
Injection Aminophylline 1 & 2 mg/ml
Injection Cefuroxime sodium 7,5 & 15 mg/ml
NaCl 0,9% or Glucose 5% 96
Compatible
Injection Aminophylline 1 & 2 mg/ml
Injection Cefuroxime sodium 7,5 & 15 mg/ml
NaCl 0,45% Glucose 5% 96
Compatible
Injection Aminophylline 1 & 2 mg/ml
Injection Cefuroxime sodium 7,5 & 15 mg/ml
Sodium chloride 0,45% 96
Compatible
Injection Aminophylline 0,5 mg/ml
Injection Cimetidine hydrochloride 1,2 mg/ml
Glucose 5% 539
Precipitation after 4 hours Incompatible
Injection Aminophylline 1.2 mg/ml
Injection Ciprofloxacin lactate 1.5 mg/ml
NaCl 0,9% or Glucose 5% 434
Precipitation after 15 minutes Incompatible
Injection Aminophylline 2 mg/ml
Injection Ciprofloxacin lactate 2 mg/ml
NaCl 0,9% or Glucose 5% 288
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Cisatracurium besylate 0.1 & 2 mg/ml
Glucose 5% 299
Turbidity in one hour Incompatible
Injection Aminophylline 2.5 mg/ml
Injection Cisatracurium besylate 5 mg/ml
Glucose 5% 299
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Cladribine 0.015 mg/ml
Sodium chloride 0,9% 1496
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Cladribine 0.5 mg/ml
NaCl 0,9% + antibacterial 1496
Unspecified incompatibility Incompatible
Injection Aminophylline
Injection Clindamycin phosphate
3526
Compatible
Injection Aminophylline 0,9 mg/ml
Injection Clonidine hydrochloride 0,018 mg/ml
Sodium chloride 0,9% 2018
Compatible
Injection Aminophylline 0,625 mg/ml
Injection Dexamethasone sodium phosphate 0,03 mg/ml
Glucose 5% 1259
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Dexmedetomidine 4 µg/ml
Sodium chloride 0,9% 1712
Compatible
Injection Aminophylline 25 mg/ml
Injection Diltiazem hydrochloride 1 mg/ml
Sodium chloride 0,9% 198
Compatible
Injection Aminophylline 2 mg/ml
Injection Diltiazem hydrochloride 5 mg/ml
Sodium chloride 0,9% 198
Immediate turbidity Incompatible
Injection Aminophylline 25 mg/ml
Injection Diltiazem hydrochloride 5 mg/ml
Sodium chloride 0,9% 198
Immediate precipitation Incompatible
Injection Aminophylline
Injection Dimenhydrinate
2087
Turbidity in 4 hours Incompatible
Injection Aminophylline 1 mg/ml
Injection Dobutamine hydrochloride 1 mg/ml
NaCl 0,9% or Glucose 5% 1058
Precipitation after 12 hours Incompatible
Injection Aminophylline 5 mg/ml
Injection Dobutamine hydrochloride 2 mg/ml
Glucose 5% 1041
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Docetaxel 0.9 mg/ml
Glucose 5% 1754
Color change after 2 hours Incompatible
Injection Aminophylline 25 mg/ml
Injection Dopamine hydrochloride 3 mg/ml
Glucose 5% 3759
Compatible
Injection Aminophylline 2,5 mg/ml
Injection Doripenem 5 mg/ml
NaCl 0,9% or Glucose 5% 2262
Unspecified incompatibility Incompatible
Injection Aminophylline
Injection Doxapram hydrochloride
3612
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Doxorubicin hydrochloride liposome peg 0.4 mg/ml
Glucose 5% 251
Compatible
Injection Aminophylline 1 mg/ml
Injection Enalaprilate 0.05 mg/ml
Sodium chloride 0,9% 1315
Unspecified incompatibility Incompatible
Injection Aminophylline
Injection Erythromycin lactobionate
3674
Compatible
Injection Aminophylline 1 mg/ml
Injection Esmolol hydrochloride 6 mg/ml
Glucose 5% 174
Compatible
Injection Aminophylline 1 mg/ml
Injection Esmolol hydrochloride 10 mg/ml
Glucose 5% 384
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Etoposide phosphate 5 mg/ml
Glucose 5% 1410
Compatible
Injection Aminophylline 1 mg/ml
Injection Flucloxacillin sodium 20 mg/ml
Sodium chloride 0,9% 1232
Compatible
Injection Aminophylline 25 mg/ml
Injection Fluconazole 2 mg/ml
Sodium chloride 0,9% 496
Compatible
Injection Aminophylline 1 & 2 mg/ml
Injection Fluconazole 0.5 & 1.5 mg/ml
NaCl 0,9% or Glucose 5% 262
Compatible
Injection Aminophylline 2.5 mg/ml
Parenteral nutrition (binary mixture) 301
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Famotidine 2 mg/ml
Sodium chloride 0,9% 215
Immediate precipitation Incompatible
Injection Aminophylline 2.5 mg/ml
Injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Fludarabine phosphate 1 mg/ml
Glucose 5% 492
Compatible
Injection Aminophylline 1 mg/ml
Parenteral nutrition (binary mixture) 939
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Filgrastim 30 µg/ml
Glucose 5% 244
Compatible
Injection Aminophylline 0.25 >> 1.5 mg/ml
Parenteral nutrition (binary mixture) 1188
Immediate precipitation Incompatible
Injection Aminophylline 5 & 25 mg/ml
Parenteral nutrition (binary mixture) 316
Compatible
Injection Aminophylline 2,5 mg/ml
Injection Famotidine
Glucose 5% 397
Compatible
Injection Aminophylline 2 mg/ml
Injection Flumazenil 0,02 mg/ml
Glucose 5% 187
Compatible
Injection Aminophylline 2.5 mg/ml
Parenteral nutrition (with lipids) 1415
Compatible
Injection Aminophylline 25 mg/ml
Injection Foscarnet sodium 24 mg/ml
None 73
Compatible
Injection Aminophylline 25 mg/ml
Ringer’s lactate solution 4603
Compatible
Injection Aminophylline 1 mg/ml
Injection Furosemide 1 mg/ml
Sodium chloride 0,9% 1232
Compatible
Injection Aminophylline 25 mg/ml
Injection Gallium nitrate 1 mg/ml
Sodium chloride 0,9% 91
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Gemcitabine hydrochloride 10 mg/ml
Sodium chloride 0,9% 1423
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Granisetron hydrochloride 0.05 mg/ml
Glucose 5% 182
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Hetastarch 60 mg/ml
Specific solvent 1721
Chemical instability Incompatible
Injection Aminophylline 0,625 mg/ml
Injection Hydrocortisone sodium succinate 0,25 mg/ml
Glucose 5% 1259
Immediate turbidity Incompatible
Injection Aminophylline 50 mg/ml
Injection Ketamine hydrochloride 50 mg/ml
2109
Immediate precipitation Incompatible
Injection Aminophylline 25 mg/ml
Injection Ketamine hydrochloride 50 mg/ml
4389
Compatible
Injection Aminophylline 1 mg/ml
Injection Labetalol hydrochloride 1 mg/ml
Glucose 5% 386
Precipitation after 4 hours Incompatible
Injection Aminophylline 2.5 mg/ml
Injection Lansoprazole 0.55 mg/ml
Sodium chloride 0,9% 1625
Compatible
Injection Aminophylline 25 mg/ml
Injection Levofloxacine 5 mg/ml
Glucose 5% 1072
Compatible
Injection Aminophylline 1 mg/ml
Injection Lidocaine hydrochloride 2 mg/ml
Ringer’s lactate solution 619
Compatible
Injection Aminophylline 1 mg/ml
Injection Lidocaine hydrochloride 2 mg/ml
NaCl 0,9% or Glucose 5% 619
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Linezolid 2 mg/ml
None 1925
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Melphalan 0.1 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Aminophylline 25 mg/ml
Injection Meropenem 1 & 50 mg/ml
Sodium chloride 0,9% 266
Compatible
Injection Aminophylline 1 mg/ml
Injection Meropenem 1 & 20 mg/ml
Sodium chloride 0,9% 266
Unspecified incompatibility Incompatible
Injection Aminophylline
Injection Mesna
3602
Chemical instability Incompatible
Injection Aminophylline 1 mg/ml
Injection Methylprednisolone sodium succinate 0,5 & 2 mg/ml
NaCl 0,9% or Glucose 5% 390
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Micafungin 1.5 mg/ml
Sodium chloride 0,9% 2108
Compatible
Injection Aminophylline 0.72 mg/ml
Injection Midazolam hydrochloride 0.05 mg/ml
Sodium chloride 0,9% 1888
Immediate precipitation Incompatible
Injection Aminophylline 0.72 mg/ml
Injection Midazolam hydrochloride 0.25 & 0.4 mg/ml
Sodium chloride 0,9% 1888
Unspecified incompatibility Incompatible
Injection Aminophylline
Injection Morphine sulfate
3531
Unspecified incompatibility Incompatible
Injection Aminophylline 50 mg/ml
Injection N-acetylcysteine 200 mg/ml
None 3766
Unspecified incompatibility Incompatible
Injection Aminophylline 50 mg/ml
Injection Naloxone hydrochloride 0.4 mg/ml
None 3408
Compatible
Injection Aminophylline 0,8 mg/ml
Injection Netilmicin sulfate 5 mg/ml
NaCl 0,45% Glucose 5% 1236
Compatible
Injection Aminophylline 1 mg/ml
Injection Nicardipine hydrochloride 0.1 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Aminophylline 1 mg/ml
Injection Nitroglycerin 0.4 mg/ml
NaCl 0,9% or Glucose 5% 1049
Immediate precipitation Incompatible
Injection Aminophylline 2.5 mg/ml
Injection Ondansetron hydrochloride 1 mg/ml
Sodium chloride 0,9% 334
Precipitation after 1 hour Incompatible
Injection Aminophylline 1 mg/ml
Injection Oritavancin 0.8 >>2 mg/ml
Glucose 5% 3152
Compatible
Injection Aminophylline 2,5 mg/ml
Injection Oxaliplatin 0,5 mg/ml
Glucose 5% 1662
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Paclitaxel 1.2 mg/ml
Glucose 5% 248
Compatible
Injection Aminophylline 1 mg/ml
Injection Pancuronium bromide 0.05 mg/ml
Glucose 5% 402
Compatible
Injection Aminophylline
Injection Pantoprazole sodium
2090
Compatible
Injection Aminophylline 25 mg/ml
Injection Paracetamol 10 mg/ml
4742
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Pemetrexed disodium 20 mg/ml
Sodium chloride 0,9% 1953
Immediate turbidity Incompatible
Injection Aminophylline
Injection Pethidine hydrochloride
3525
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Piperacillin sodium / tazobactam 40/5 mg/ml
Glucose 5% 81
Compatible
Injection Aminophylline 25 mg/ml
Injection Potassium chloride 40 mEq/l
NaCl 0,9% or Glucose 5% 730
Compatible
Injection Aminophylline 25 mg/ml
Injection Potassium chloride 40 mEq/l
Ringer’s lactate solution 730
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Propofol 10 mg/ml
None 300
Compatible
Injection Aminophylline 0.5 & 2 mg/ml
Injection Ranitidine hydrochloride 0.05 & 2 mg/ml
NaCl 0,9% or Glucose 5% 214
Compatible
Injection Aminophylline 4 mg/ml
Injection Ranitidine hydrochloride 0,5 mg/ml
Glucose 5% 396
Compatible
Injection Aminophylline 0.5 & 2 mg/ml
Injection Ranitidine hydrochloride 0.05 & 2 mg/ml
NaCl 0,9% or Glucose 5% 210
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Remifentanil hydrochloride 25 & 250 µg/ml
Sodium chloride 0,9% 59
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Sargramostim 10 µg/ml
Sodium chloride 0,9% 335
Compatible
Injection Aminophylline 24 mg/ml
Injection Sugammadex 100 mg/ml
None 3372
Compatible
Injection Aminophylline 2 mg/ml
Injection Tacrolimus 1000 µg/ml
Sodium chloride 0,9% 479
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Teniposide 0.1 mg/ml
Glucose 5% 905
Compatible
Injection Aminophylline 2.5 mg/ml
Injection Thiotepa 1 mg/ml
Glucose 5% 249
Unspecified incompatibility Incompatible
Injection Aminophylline
Injection Vancomycin hydrochloride
3588
Compatible
Injection Aminophylline 1 mg/ml
Injection Vecuronium bromide 0.1 mg/ml
Glucose 5% 402
Immediate precipitation Incompatible
Injection Aminophylline 1 mg/ml
Injection Verapamil hydrochloride 0,08 mg/ml
NaCl 0,9% or Glucose 5% 706
Immediate precipitation Incompatible
Injection Aminophylline 1 mg/ml
Injection Verapamil hydrochloride 0,1 & 0,4 mg/ml
Glucose 5% 364
Immediate turbidity Incompatible
Injection Aminophylline 2.5 mg/ml
Injection Vinorelbine tartrate 1 mg/ml
Sodium chloride 0,9% 84
Turbidity in 4 hours Incompatible
Injection Aminophylline 4 mg/ml
Injection Warfarin sodium 2 mg/ml
Glucose 5% 315

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