Last update :
13/11/2024
Anticancer drug   Bleomycin sulfate  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Bileco Argentina
Blemisin Turkey
Blenamax Australia, Colombia, Malaysia
Blenoxane Australia, United States of America
Bleo-Kyowa Great Britain
Bleocell Germany
Bleocin Greece, Hungary, Japan, Malaysia, Peru, Poland, Portugal, Saudi Arabia, Turkey, United Arab Emirates
Bleocip Egypt, Venezuela
Bleocris Argentina, Chile, Peru
Bleolem Colombia, Mexico
Bleomax Mexico
Bleomedac Germany
Bleomicina Chile, Colombia, Ecuador, Italy, Mexico, Peru, Spain
Bleomycin Australia, Austria, Denmark, Finland, Germany, Great Britain, Hungary, Iceland, Iran, Netherlands, Norway, Poland, Romania, Sweden, United States of America
Bleomycine Belgium, Canada, France, Ireland, Luxembourg, Malaysia, Morocco, New Zealand, Switzerland, Tunisia
Bleomycine A Denmark
Bleomycinum Germany
Bleozen Peru
Blexit Chile
Blocamicina Argentina
Bloicin Egypt, Peru
Blomindex Mexico
Blucin Morocco
DBL Bleomycin Malaysia, New Zealand
Ifabec Mexico
Lyoble Peru
Nikableocina Chile
Oncobleocin Colombia
Compatibility   injection   Compatibility : Bleomycin sulfate              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
injection Bleomycin sulfate 1 mg/ml
injection Allopurinol sodium 3 mg/ml
Sodium chloride 0,9% 307
Chemical instability Incompatible
injection Bleomycin sulfate
Glucose 5% 252
Compatible
injection Bleomycin sulfate 1 mg/ml
injection Amifostine 10 mg/ml
Glucose 5% 3
Unspecified incompatibility Incompatible
injection Bleomycin sulfate
injection Aminophylline
4154
Unspecified incompatibility Incompatible
injection Bleomycin sulfate
injection Aminophylline
3646
Unspecified incompatibility Incompatible
injection Bleomycin sulfate
injection Ascorbic acid
4154
Unspecified incompatibility Incompatible
injection Bleomycin sulfate
injection Ascorbic acid
3646
Compatible
injection Bleomycin sulfate 1 mg/ml
injection Aztreonam 40 mg/ml
Glucose 5% 99
Chemical instability Incompatible
injection Bleomycin sulfate
injection Calcium chloride
4154
Chemical instability Incompatible
injection Bleomycin sulfate
injection Calcium glucoheptonate
4154
Unspecified incompatibility Incompatible
injection Bleomycin sulfate
injection Calcium gluconate
3644
Chemical instability Incompatible
injection Bleomycin sulfate
injection Calcium gluconate
4154
Unspecified incompatibility Incompatible
injection Bleomycin sulfate
injection Cefalotin sodium
4154
Unspecified incompatibility Incompatible
injection Bleomycin sulfate
injection Cefazolin sodium
4154
Chemical instability Incompatible
injection Bleomycin sulfate
injection Cisplatin
3578
Unspecified incompatibility Incompatible
injection Bleomycin sulfate
injection Dexamethasone sodium phosphate
3646
Unspecified incompatibility Incompatible
injection Bleomycin sulfate
injection Dexamethasone sodium phosphate
4154
Unspecified incompatibility Incompatible
injection Bleomycin sulfate
injection Diazepam
4154
Compatible
injection Bleomycin sulfate 1 mg/ml
injection Doxorubicin hydrochloride liposome peg 0.4 mg/ml
Glucose 5% 251
Compatible
injection Bleomycin sulfate 1 mg/ml
injection Etoposide phosphate 5 mg/ml
Sodium chloride 0,9% 1410
Compatible
injection Bleomycin sulfate 1 mg/ml
injection Filgrastim 30 µg/ml
Glucose 5% 244
Compatible
injection Bleomycin sulfate 1 mg/ml
injection Fludarabine phosphate 1 mg/ml
Glucose 5% 492
Chemical instability Incompatible
injection Bleomycin sulfate
injection Folinate calcium
4154
Unspecified incompatibility Incompatible
injection Bleomycin sulfate
injection Furosemide
4154
Unspecified incompatibility Incompatible
injection Bleomycin sulfate
Parenteral nutrition (with lipids) 4154
Unspecified incompatibility Incompatible
injection Bleomycin sulfate
injection Furosemide
3646
Compatible
injection Bleomycin sulfate 1 mg/ml
injection Gemcitabine hydrochloride 10 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Bleomycin sulfate 1 mg/ml
injection Granisetron hydrochloride 0.05 mg/ml
Sodium chloride 0,9% 182
Unspecified incompatibility Incompatible
injection Bleomycin sulfate
injection Hydrocortisone sodium succinate
4154
Chemical instability Incompatible
injection Bleomycin sulfate
injection Levofolinate calcium
4154
Chemical instability Incompatible
injection Bleomycin sulfate
injection Magnesium sulfate
4154
Unspecified incompatibility Incompatible
injection Bleomycin sulfate
Parenteral nutrition (binary mixture) 4154
Compatible
injection Bleomycin sulfate 1 mg/ml
injection Melphalan 0.1 mg/ml
Sodium chloride 0,9% 169
Unspecified incompatibility Incompatible
injection Bleomycin sulfate
injection Methotrexate sodium
4154
Chemical instability Incompatible
injection Bleomycin sulfate
injection Mitomycin
3128
Unspecified incompatibility Incompatible
injection Bleomycin sulfate
injection Mitomycin
4471
Unspecified incompatibility Incompatible
injection Bleomycin sulfate
injection Mitomycin
4154
Unspecified incompatibility Incompatible
injection Bleomycin sulfate
injection Nafcillin sodium
4154
Compatible
injection Bleomycin sulfate 1 mg/ml
injection Ondansetron hydrochloride 1 mg/ml
Sodium chloride 0,9% 334
Compatible
injection Bleomycin sulfate 1 mg/ml
injection Paclitaxel 1.2 mg/ml
Glucose 5% 248
Unspecified incompatibility Incompatible
injection Bleomycin sulfate
injection Penicillin G potassium
4154
Unspecified incompatibility Incompatible
injection Bleomycin sulfate
injection Penicillin G sodium
4154
Compatible
injection Bleomycin sulfate 1 mg/ml
injection Piperacillin sodium / tazobactam 40/5 mg/ml
Glucose 5% 81
Compatible
injection Bleomycin sulfate 1 mg/ml
injection Sargramostim 10 µg/ml
Sodium chloride 0,9% 335
Compatible
injection Bleomycin sulfate 1 mg/ml
injection Teniposide 0.1 mg/ml
Glucose 5% 905
Unspecified incompatibility Incompatible
injection Bleomycin sulfate
injection Terbutaline sulfate
4154
Compatible
injection Bleomycin sulfate 1 mg/ml
injection Thiotepa 1 mg/ml
Glucose 5% 249
Compatible
injection Bleomycin sulfate 1 mg/ml
injection Vinorelbine tartrate 1 mg/ml
Sodium chloride 0,9% 84

  Mentions Légales