Last update :
09/04/2024
Antibiotic   Ceftriaxone disodium  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Acantex Argentina, Chile
Amcef Mexico
Antibacin Greece
Aurofox
Axobat Italy
Azatyl Greece
Baktisef Turkey
Biotrakson Poland
Bixon Italy
Bresec Greece
Cefaday Turkey
Cefonova Sweden
Cefotrix Austria, Denmark, Germany
Cefrag Italy
Cephaxon Turkey
Davixon Italy
Daytrix Italy
Deixim Italy
Desefin Turkey
Eftry Italy
Eqicept Turkey
Farcef Greece
Fidato Italy
Forsef Turkey
Frineg Italy
Gladius Greece
Glorixone Greece
Kappacef Italy
Labilex Greece
Lendacin Croatia, Poland, Russian, Slovenia
Lidacef Croatia
Mesporin Portugal, Saudi Arabia
Nevakson Turkey
Nilson Italy
Novocef Turkey
Oframax Texte introuvable (616, ), Poland
Olisef Slovenia
Panatrix Italy
Pantoxon Italy
Ragex Italy
Rocefalin Spain
Rocefin Brazil, Italy
Rocephalin Denmark, Finland, Norway, Sweden
Rocephin Canada, Germany, Greece, Netherlands, Poland, Portugal, Republic of South Africa, Switzerland, Thailand, Turkey, United States of America
Rocephine Belgium, France, Germany
Sirtap Italy
Tartriakson Poland
Tercefon Austria
Travilan Greece
Unacefin Turkey
Valexime Italy
Compatibility   Injection   Compatibility : Ceftriaxone disodium              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Aciclovir sodium 5 mg/ml
Glucose 5% 336
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Allopurinol sodium 3 mg/ml
Sodium chloride 0,9% 307
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Amifostine 10 mg/ml
Glucose 5% 3
Unspecified incompatibility Incompatible
Injection Ceftriaxone disodium
Injection Amikacin sulfate
3523
Chemical instability Incompatible
Injection Ceftriaxone disodium 20 & 40 mg/ml
Injection Aminophylline 1 & 4 mg/ml
NaCl 0,9% or Glucose 5% 276
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Amiodarone hydrochloride 6 mg/ml
Glucose 5% 1611
Compatible
Injection Ceftriaxone disodium 100 mg/ml
Injection Amoxicillin sodium / clavulanic acid 100/10 mg/ml
3824
Loss of turbidity Incompatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Amphotericin B cholesteryl sulfate complex 0.83 mg/ml
Glucose 5% 921
Immediate precipitation Incompatible
Injection Ceftriaxone disodium 40 mg/ml
Injection Amsacrine 1 mg/ml
Glucose 5% 253
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Anidulafungin 0.5 mg/ml
Glucose 5% 1982
Immediate precipitation Incompatible
Injection Ceftriaxone disodium 66.7 mg/ml
Injection Azithromycine 2 mg/ml
Sodium chloride 0,9% 1800
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Aztreonam 40 mg/ml
Glucose 5% 99
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Bivalirudin 5 mg/ml
Glucose 5% 1713
Immediate precipitation Incompatible
Injection Ceftriaxone disodium 50 mg/ml
Injection Blinatumomab 0.125 & 0.375 µg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
Injection Ceftriaxone disodium
Injection Calcium glucoheptonate
3523
Compatible
Injection Ceftriaxone disodium 40 mg/ml
Injection Ceftolozane / tazobactam 10/5 mg/ml
NaCl 0,9% or Glucose 5% 3828
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Cisatracurium besylate 0.1 >> 5 mg/ml
Glucose 5% 299
Chemical instability Incompatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Clindamycin phosphate 12 mg/ml
NaCl 0,9% or Glucose 5% 432
Compatible
Injection Ceftriaxone disodium 100 mg/ml
Injection Cloxacillin sodium 100 mg/ml
Water for Injection 3012
Compatible
Injection Ceftriaxone disodium 16,7 mg/ml
Injection Daptomycin 16,7 mg/ml
Sodium chloride 0,9% 1937
Compatible
Injection Ceftriaxone disodium
Injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
Sodium chloride 0,9% 4654
Incompatible
Injection Ceftriaxone disodium
Ringer’s lactate solution 1744
Immediate precipitation Incompatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Caspofungin acetate 0.5 mg/ml
Sodium chloride 0,9% 2233
Compatible
Injection Ceftriaxone disodium 100 mg/ml
Parenteral nutrition (binary mixture) 939
Compatible
Injection Ceftriaxone disodium 100 mg/ml
NaHCO3 150
Unspecified incompatibility Incompatible
Injection Ceftriaxone disodium
Injection Amsacrine
3523
Immediate precipitation Incompatible
Injection Ceftriaxone disodium
Injection Calcium chloride
3523
Unspecified incompatibility Incompatible
Injection Ceftriaxone disodium
Injection Calcium gluconate
3644
Immediate precipitation Incompatible
Injection Ceftriaxone disodium
Injection Calcium gluconate
2302
Unspecified incompatibility Incompatible
Injection Ceftriaxone disodium
Injection Clindamycin phosphate
3526
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Parenteral nutrition (binary mixture) 301
Immediate precipitation Incompatible
Injection Ceftriaxone disodium
Injection Calcium gluconate
3523
Immediate precipitation Incompatible
Injection Ceftriaxone disodium
Parenteral nutrition (binary mixture) 3523
Immediate precipitation Incompatible
Injection Ceftriaxone disodium
Ringer’s lactate solution 3523
Compatible
Injection Ceftriaxone disodium 100 mg/ml
Injection Caffeine 10 mg/ml
None 3964
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Parenteral nutrition (with lipids) 1415
Compatible
Injection Ceftriaxone disodium 10 mg/ml
Parenteral nutrition (with lipids) 4440
Chemical instability Incompatible
Injection Ceftriaxone disodium
Injection Amikacin sulfate
3549
Immediate precipitation Incompatible
Injection Ceftriaxone disodium
Parenteral nutrition (with lipids) 3523
Immediate precipitation Incompatible
Injection Ceftriaxone disodium
Parenteral nutrition (with lipids) 2238
Compatible
Injection Ceftriaxone disodium 100 mg/ml
Ringer’s lactate solution 4603
Immediate precipitation Incompatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Caspofungin acetate 0,7 mg/ml
Sodium chloride 0,9% 2247
Compatible
Injection Ceftriaxone disodium
Injection Daptomycin
2271
Compatible
Injection Ceftriaxone disodium 100 mg/ml
Injection Defibrotide 8 mg/ml
Sodium chloride 0,9% 3728
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Dexmedetomidine 4 µg/ml
Sodium chloride 0,9% 1712
Compatible
Injection Ceftriaxone disodium 40 mg/ml
Injection Diltiazem hydrochloride 5 mg/ml
Sodium chloride 0,9% 198
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Docetaxel 0.9 mg/ml
Glucose 5% 1754
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Doxorubicin hydrochloride liposome peg 0.4 mg/ml
Glucose 5% 251
Unspecified incompatibility Incompatible
Injection Ceftriaxone disodium
Injection Erythromycin lactobionate
3674
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Etoposide phosphate 5 mg/ml
Glucose 5% 1410
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Famotidine 2 mg/ml
Sodium chloride 0,9% 215
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Precipitation after 1 hour Incompatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Filgrastim 30 µg/ml
Glucose 5% 244
Immediate precipitation Incompatible
Injection Ceftriaxone disodium 40 mg/ml
Injection Fluconazole 2 mg/ml
Sodium chloride 0,9% 496
Unspecified incompatibility Incompatible
Injection Ceftriaxone disodium
Injection Fluconazole
3523
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Fludarabine phosphate 1 mg/ml
Glucose 5% 492
Immediate precipitation Incompatible
Injection Ceftriaxone disodium
Injection Folinate calcium
3523
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Foscarnet sodium 24 mg/ml
NaCl 0,9% or Glucose 5% 1135
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Fosfomycin 30 mg/ml
NaCl 0,9% or Glucose 5% 4055
Compatible
Injection Ceftriaxone disodium 40 mg/ml
Injection Gallium nitrate 1 mg/ml
Sodium chloride 0,9% 91
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Gemcitabine hydrochloride 10 mg/ml
Sodium chloride 0,9% 1423
Unspecified incompatibility Incompatible
Injection Ceftriaxone disodium
Injection Gentamicin sulfate
3520
Unspecified incompatibility Incompatible
Injection Ceftriaxone disodium
Injection Gentamicin sulfate
3643
Unspecified incompatibility Incompatible
Injection Ceftriaxone disodium
Injection Gentamicin sulfate
3523
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Granisetron hydrochloride 0.05 mg/ml
Glucose 5% 182
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Heparin sodium 50 UI/ml
None 317
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Hetastarch 60 mg/ml
Specific solvent 1721
Compatible
Injection Ceftriaxone disodium 10 & 50 mg/ml
Injection Insulin aspart 1 UI/ml
NaCl 0,9% or Glucose 5% 1508
Immediate turbidity Incompatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Isavuconazonium sulfate 1.5 mg/ml
NaCl 0,9% or Glucose 5% 3829
Unspecified incompatibility Incompatible
Injection Ceftriaxone disodium
Injection Kanamycin sulfate
3523
Compatible
Injection Ceftriaxone disodium 40 mg/ml
Injection Ketoprofene 3.2 mg/ml
Sodium chloride 0,9% 1847
Immediate precipitation Incompatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Labetalol hydrochloride 5 & 2,5 mg/ml
NaCl 0,9% or Glucose 5% 241
Immediate precipitation Incompatible
Injection Ceftriaxone disodium 100 mg/ml
Injection Labetalol hydrochloride 5 & 2,5 mg/ml
Water for Injection 241
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Lansoprazole 0.55 mg/ml
Sodium chloride 0,9% 1625
Immediate precipitation Incompatible
Injection Ceftriaxone disodium
Injection Levofolinate calcium
Ringer’s lactate solution 3523
Immediate precipitation Incompatible
Injection Ceftriaxone disodium
Injection Levofolinate calcium
3523
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Linezolid 2 mg/ml
None 1925
Unspecified incompatibility Incompatible
Injection Ceftriaxone disodium
Injection Linezolid
3560
Chemical instability Incompatible
Injection Ceftriaxone disodium 10 mg/ml
Injection Linezolid 2 mg/ml
None 1659
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Melphalan 0.1 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Ceftriaxone disodium 100 mg/ml
Injection Meropenem 50 mg/ml
Water for Injection 4319
Compatible
Injection Ceftriaxone disodium 100 mg/ml
Injection Methotrexate sodium 30 mg/ml
Sodium chloride 0,9% 150
Compatible
Injection Ceftriaxone disodium 10 mg/ml
Injection Metronidazole 7.5 mg/ml
NaCl 0,9% or Glucose 5% 11
Compatible
Injection Ceftriaxone disodium 10 mg/ml
Injection Metronidazole 5 mg/ml
None 282
Compatible
Injection Ceftriaxone disodium 10 mg/ml
Injection Metronidazole 5 mg/ml
None 649
Immediate precipitation Incompatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Metronidazole 15 mg/ml
NaCl 0,9% or Glucose 5% 11
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Milrinone lactate 0,2 mg/ml
Glucose 5% 4144
Compatible
Injection Ceftriaxone disodium 20 & 40 mg/ml
Injection Morphine sulfate 1 mg/ml
Glucose 5% 62
Compatible
Injection Ceftriaxone disodium
Injection N-acetylcysteine 200 mg/ml
None 3766
Compatible
Injection Ceftriaxone disodium 100 mg/ml
Injection Naloxone hydrochloride 0.4 mg/ml
None 3408
Unspecified incompatibility Incompatible
Injection Ceftriaxone disodium
Injection Netilmicin sulfate
3523
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Paclitaxel 1.2 mg/ml
Glucose 5% 248
Compatible
Injection Ceftriaxone disodium 20 >> 40 mg/ml
Injection Pantoprazole sodium 0.16 >> 0.8 mg/ml
Sodium chloride 0,9% 1902
Compatible
Injection Ceftriaxone disodium 40 mg/ml
Injection Paracetamol 10 mg/ml
None 3571
Compatible
Injection Ceftriaxone disodium 100 mg/ml
Injection Paracetamol 10 mg/ml
4742
Compatible
Injection Ceftriaxone disodium 0,22 mg/ml
NaCl 0.225 % + glucose 3.75% 4693
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Pemetrexed disodium 20 mg/ml
Sodium chloride 0,9% 1953
Immediate precipitation Incompatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Pentamidine isetionate 3 mg/ml
Glucose 5% 275
Compatible
Injection Ceftriaxone disodium 20 & 40 mg/ml
Injection Pethidine hydrochloride 10 mg/ml
Glucose 5% 62
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Phloroglucinol 2,5 mg/ml
3791
Unspecified incompatibility Incompatible
Injection Ceftriaxone disodium
Injection Plazomicin sulfate
3523
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Plazomicin sulfate 24 mg/ml
Sodium chloride 0,9% 4145
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Propofol 10 mg/ml
None 300
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Remifentanil hydrochloride 25 & 250 µg/ml
Sodium chloride 0,9% 59
Compatible
Injection Ceftriaxone disodium 100 mg/ml
Injection Salbutamol sulfate 1 mg/ml
None 3216
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Sargramostim 10 µg/ml
Sodium chloride 0,9% 335
Compatible
Injection Ceftriaxone disodium 100 mg/ml
Injection Sodium bicarbonate 14 mg/ml
None 150
Unspecified incompatibility Incompatible
Injection Ceftriaxone disodium
Injection Streptomycin sulfate
3523
Compatible
Injection Ceftriaxone disodium 40 mg/ml
Injection Tacrolimus 1000 µg/ml
Sodium chloride 0,9% 479
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Tedizolid phosphate 0.8 mg/ml
Sodium chloride 0,9% 3827
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Telavancin hydrochloride 7.5 mg/ml
NaCl 0,9% or Glucose 5% 3254
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Teniposide 0.1 mg/ml
Glucose 5% 905
Chemical instability Incompatible
Injection Ceftriaxone disodium 20 & 40 mg/ml
Injection Theophylline 4 mg/ml
NaCl 0,9% or Glucose 5% 276
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Theophylline 4 mg/ml
None 317
Precipitation after 1 hour Incompatible
Injection Ceftriaxone disodium 100 mg/ml
Injection Thiopental sodium 25 mg/ml
Sodium chloride 0,9% 3767
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Thiotepa 1 mg/ml
Glucose 5% 249
Unspecified incompatibility Incompatible
Injection Ceftriaxone disodium
Injection Tobramycin sulfate
3523
Immediate precipitation Incompatible
Injection Ceftriaxone disodium 100 mg/ml
Injection Vancomycin hydrochloride 20 mg/ml
Water for Injection 95
Compatible
Injection Ceftriaxone disodium 1 >> 250 mg/ml
Injection Vancomycin hydrochloride 2 mg/ml
Glucose 5% 1674
Unspecified incompatibility Incompatible
Injection Ceftriaxone disodium
Injection Vancomycin hydrochloride
3523
Immediate precipitation Incompatible
Injection Ceftriaxone disodium 1 >> 250 mg/ml
Injection Vancomycin hydrochloride 20 mg/ml
Glucose 5% 1674
Immediate precipitation Incompatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Vinorelbine tartrate 1 mg/ml
Sodium chloride 0,9% 84
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Warfarin sodium 2 mg/ml
Glucose 5% 315
Compatible
Injection Ceftriaxone disodium 20 mg/ml
Injection Zidovudine 4 mg/ml
Glucose 5% 337

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