Last update :
06/12/2024
Antiemetic   Granisetron hydrochloride  
injection
Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Axigran Germany, Saudi Arabia
Cadigran India
Cetrexon Colombia
Em Ex Egypt
Emegran India
Emetril Turkey
Grandem India
Granic Iran
Granicip India
Graniset India
Granisetrom Portugal
Granisetron Belgium, Canada, Chile, Ecuador, Egypt, Great Britain, Mexico, Peru, Romania, Saudi Arabia, Spain, Sweden, United States of America
Granitero Portugal
Granitron Austria
Granon India
Granytril India
Gratil Iran
Gratryl Turkey
Helminar Peru
Kevatril Germany
Kytril Australia, Austria, Belgium, Brazil, Chile, Colombia, Denmark, Ecuador, Egypt, Finland, Germany, Great Britain, Greece, Hungary, Iran, Ireland, Italy, Japan, Luxembourg, Malaysia, Mexico, Morocco, Netherlands, Peru, Poland, Portugal, Saudi Arabia, Spain, Sweden, Switzerland, Tunisia, Turkey, United Arab Emirates, Venezuela
Manotrox Mexico
Neoset Turkey
Ribosetron Germany
Rubrum Venezuela
Suliftop Peru
Synarex Turkey
Tentratec Mexico
Tigron Turkey
Travigan Mexico
Trilemes Mexico
Vitasetron Turkey
Stability in solutions   injection   Stability in solutions : Granisetron hydrochloride     
Container Solvent Concentration Temperature Storage Duration of stability References
Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,02 & 0,06 mg/ml 23°C Not specified
35 Day
1633
Level of evidence A

Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,02 & 0,06 mg/ml 4°C Protect from light
35 Day
1633
Level of evidence A

Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,056 mg/ml -20°C Protect from light
30 Day
29

Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,056 mg/ml 20°C Protect from light
3 Day
29

Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,056 mg/ml 4°C Protect from light
7 Day
29

Polypropylen Syringe NaCl 0,9% or Glucose 5% 0,05 & 0,1 mg/ml 24°C Protect from light
14 Day
48
Level of evidence A

Polypropylen Syringe NaCl 0,9% or Glucose 5% 0,05 & 0,1 mg/ml 5°C Protect from light
14 Day
48
Level of evidence A

Polypropylen Syringe NaCl 0,9% or Glucose 5% 0,15 mg/ml -20°C Protect from light
30 Day
29

Polypropylen Syringe NaCl 0,9% or Glucose 5% 0,15 mg/ml 20°C Protect from light
3 Day
29

Polypropylen Syringe NaCl 0,9% or Glucose 5% 0,15 mg/ml 4°C Protect from light
7 Day
29

Polypropylen Syringe None 1 mg/ml 25°C With or without light
15 Day
1676
Level of evidence D

Polypropylen Syringe None 1 mg/ml 4°C Protect from light
15 Day
1676
Level of evidence D

Polyisoprene elastomer Sodium chloride 0,9% 0,02 mg/ml 4°C Protect from light
7 Day
51
Level of evidence C

Polyisoprene elastomer Glucose 5% 0,02 mg/ml 4°C Protect from light
14 Day
51
Level of evidence C


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