Last update :
17/04/2024
Neuroleptic   Prochlorperazine edysilate  
Injection
Nasal drops
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Prochlorperazine injection Great Britain
Stemetil Great Britain
Compatibility   Injection   Compatibility : Prochlorperazine edysilate              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Immediate turbidity Incompatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Allopurinol sodium 3 mg/ml
Sodium chloride 0,9% 307
Immediate turbidity Incompatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Amifostine 10 mg/ml
Glucose 5% 3
Compatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Parenteral nutrition (binary mixture) 301
Compatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Parenteral nutrition (with lipids) 1415
Chemical instability Incompatible
Injection Prochlorperazine edysilate 5 mg/ml
Injection Aldesleukin 0.0338 MUI/ml
Glucose 5% 36
Immediate precipitation Incompatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Amphotericin B cholesteryl sulfate complex 0.83 mg/ml
Glucose 5% 921
Compatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Amsacrine 1 mg/ml
Glucose 5% 253
Turbidity in 4 hours Incompatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Aztreonam 40 mg/ml
Glucose 5% 99
Immediate precipitation Incompatible
Injection Prochlorperazine edysilate 25 mg/ml
Injection Bivalirudin
3539
Immediate precipitation Incompatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Bivalirudin 5 mg/ml
Glucose 5% 1713
Compatible
Injection Prochlorperazine edysilate 5 mg/ml
Injection Calcium gluconate 10 mg/ml
Sodium chloride 0,9% 132
Unspecified incompatibility Incompatible
Injection Prochlorperazine edysilate
Injection Calcium gluconate
3644
Immediate precipitation Incompatible
Injection Prochlorperazine edysilate 5 mg/ml
Injection Cefmetazole sodium 100 mg/ml
Water for Injection 93
Compatible
Injection Prochlorperazine edysilate 5 mg/ml
Injection Cimetidine hydrochloride 150 mg/ml
1438
Compatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Cisatracurium besylate 0.1 >> 5 mg/ml
Glucose 5% 299
Compatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Cladribine 0.5 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Cladribine 0.015 mg/ml
Sodium chloride 0,9% 1496
Compatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Dexmedetomidine 4 µg/ml
Sodium chloride 0,9% 1712
Compatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Docetaxel 0.9 mg/ml
Glucose 5% 1754
Compatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Doxorubicin hydrochloride liposome peg 0.4 mg/ml
Glucose 5% 251
Unspecified incompatibility Incompatible
Injection Prochlorperazine edysilate
Injection Erythromycin lactobionate
3674
Immediate turbidity Incompatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Etoposide phosphate 5 mg/ml
Glucose 5% 1410
Turbidity in 4 hours Incompatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Immediate precipitation Incompatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Filgrastim 30 µg/ml
Glucose 5% 244
Immediate precipitation Incompatible
Injection Prochlorperazine edysilate 1.25 mg/ml
Injection Flucloxacillin sodium 20 mg/ml
Water for Injection 1232
Compatible
Injection Prochlorperazine edysilate 5 mg/ml
Injection Fluconazole 2 mg/ml
Sodium chloride 0,9% 496
Immediate turbidity Incompatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Fludarabine phosphate 1 mg/ml
Glucose 5% 492
Immediate turbidity Incompatible
Injection Prochlorperazine edysilate 5 mg/ml
Injection Foscarnet sodium 24 mg/ml
None 73
Immediate precipitation Incompatible
Injection Prochlorperazine edysilate 1.25 mg/ml
Injection Furosemide 1 mg/ml
Water for Injection 1232
Immediate precipitation Incompatible
Injection Prochlorperazine edysilate 5 mg/ml
Injection Gallium nitrate 1 mg/ml
Sodium chloride 0,9% 91
Immediate turbidity Incompatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Gemcitabine hydrochloride 10 mg/ml
Sodium chloride 0,9% 1423
Compatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Granisetron hydrochloride 0.05 mg/ml
Glucose 5% 182
Compatible
Injection Prochlorperazine edysilate 5 mg/ml
Injection Heparin sodium 1 UI/ml
Ringer’s lactate solution 1228
Compatible
Injection Prochlorperazine edysilate 5 mg/ml
Injection Heparin sodium 1 UI/ml
NaCl 0,9% or Glucose 5% 1228
Compatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Hetastarch 60 mg/ml
Specific solvent 1721
Compatible
Injection Prochlorperazine edysilate 5 mg/ml
Injection Hydrocortisone sodium succinate 1 mg/ml
NaCl 0,9% or Glucose 5% 1228
Compatible
Injection Prochlorperazine edysilate 5 mg/ml
Injection Hydrocortisone sodium succinate 1 mg/ml
Ringer’s lactate solution 1228
Compatible
Injection Prochlorperazine edysilate 5 mg/ml
Injection Hydromorphone hydrochloride 2 >> 40 mg/ml
None 1497
Compatible
Injection Prochlorperazine edysilate 1,5 mg/ml
Injection Hydromorphone hydrochloride 0,5 mg/ml
Sodium chloride 0,9% 767
Immediate precipitation Incompatible
Injection Prochlorperazine edysilate
Injection Ketoprofene
1646
Immediate precipitation Incompatible
Injection Prochlorperazine edysilate 5 mg/ml
Injection Ketorolac tromethamine 30 mg/ml
None 476
Immediate turbidity Incompatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Lansoprazole 0.55 mg/ml
Sodium chloride 0,9% 1625
Compatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Linezolid 2 mg/ml
None 1925
Compatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Melphalan 0.1 mg/ml
Sodium chloride 0,9% 169
Immediate precipitation Incompatible
Injection Prochlorperazine edysilate 1.67 mg/ml
Injection Midazolam hydrochloride 1.67 mg/ml
None 404
Immediate precipitation Incompatible
Injection Prochlorperazine edysilate
Injection Morphine sulfate
1079
Compatible
Injection Prochlorperazine edysilate 5 mg/ml
Injection Morphine sulfate 10 mg/ml
1020
Chemical instability Incompatible
Injection Prochlorperazine edysilate
Injection Morphine tartrate
519
Compatible
Injection Prochlorperazine edysilate 5 mg/ml
Injection Nalbuphine hydrochloride 2,5 >> 10 mg/ml
616
Compatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Ondansetron hydrochloride 1 mg/ml
Sodium chloride 0,9% 334
Compatible
Injection Prochlorperazine edysilate 0,5 mg/ml
Injection Oxaliplatin 0,5 mg/ml
Glucose 5% 1662
Compatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Paclitaxel 1.2 mg/ml
Glucose 5% 85
Immediate precipitation Incompatible
Injection Prochlorperazine edysilate
Injection Pantoprazole sodium
2090
Immediate precipitation Incompatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Pemetrexed disodium 20 mg/ml
Sodium chloride 0,9% 1953
Immediate turbidity Incompatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Piperacillin sodium / tazobactam 40/5 mg/ml
Glucose 5% 81
Compatible
Injection Prochlorperazine edysilate 5 mg/ml
Injection Potassium chloride 40 mEq/l
Ringer’s lactate solution 1228
Compatible
Injection Prochlorperazine edysilate 5 mg/ml
Injection Potassium chloride 40 mEq/l
NaCl 0,9% or Glucose 5% 1228
Compatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Propofol 10 mg/ml
None 300
Compatible
Injection Prochlorperazine edysilate 5 mg/ml
Injection Ranitidine hydrochloride 25 mg/ml
None 58
Compatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Sargramostim 10 µg/ml
Sodium chloride 0,9% 335
Compatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Teniposide 0.1 mg/ml
Glucose 5% 905
Compatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Thiotepa 1 mg/ml
Glucose 5% 249
Compatible
Injection Prochlorperazine edysilate 0.192 mg/ml
Injection Topotecan 0.056 mg/ml
NaCl 0,9% or Glucose 5% 1026
Compatible
Injection Prochlorperazine edysilate 0.5 mg/ml
Injection Vinorelbine tartrate 1 mg/ml
Sodium chloride 0,9% 84

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