Last update :
25/05/2022
Antiemetic   Metoclopramide hydrochloride  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Afipran Iceland, Norway
Aristopramida Brazil
Cerucal Germany, Hungary
Clopan Ecuador, Italy
Clopram Morocco, Tunisia
Clopritec Mexico
Disgradon Argentina
Doperan Tunisia
Emperal Denmark
Eucil Brazil
Maxolon Australia, Great Britain, Republic of South Africa
Meclomid Mexico
Meclonir Colombia, Ecuador
Meclop Mexico
Meclopram Egypt
Metoclox Ecuador
Metogastron Austria
Metoplon Turkey
Metotag Argentina
Metpamid Turkey
Paspertin Austria, Switzerland
Perinorm Republic of South Africa
Plasil Brazil, Colombia, Italy
Plemazol Egypt
Pramadin Venezuela
Pramalon Republic of South Africa
Pramotil Mexico
Primperan Belgium, Colombia, Denmark, Ecuador, Egypt, Finland, France, Greece, Luxembourg, Malaysia, Morocco, Netherlands, Peru, Portugal, Saudi Arabia, Spain, Sweden, Switzerland, Tunisia, Turkey, United Arab Emirates, Venezuela
Primsel Turkey
Reglan Croatia, Slovenia, United States of America
Compatibility   Injection   Compatibility : Metoclopramide hydrochloride              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
Injection Metoclopramide hydrochloride 0.2 mg/ml
Injection Aciclovir sodium 5 mg/ml
Glucose 5% 336
Immediate precipitation Incompatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Aciclovir sodium 5 mg/ml
Sodium chloride 0,9% 2335
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Aldesleukin 0.0338 MUI/ml
Glucose 5% 36
Immediate precipitation Incompatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Allopurinol sodium 3 mg/ml
Sodium chloride 0,9% 307
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Amifostine 10 mg/ml
Glucose 5% 3
Immediate precipitation Incompatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Amphotericin B cholesteryl sulfate complex 0.83 mg/ml
Glucose 5% 921
Precipitation after 15 minutes Incompatible
Injection Metoclopramide hydrochloride 2.5 mg/ml
Injection Amsacrine 1 mg/ml
Glucose 5% 253
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Aztreonam 40 mg/ml
Glucose 5% 99
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Bivalirudin 5 mg/ml
Glucose 5% 1713
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Caffeine 10 mg/ml
None 3964
Compatible
Injection Metoclopramide hydrochloride 0.2 mg/ml
Injection Cefiderocol sulfate tosylate 20 mg/mL
NaCl 0,9% or Glucose 5% 4528
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Ceftaroline fosamil 2,22 mg/ml
Ringer’s lactate solution 3249
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Ceftaroline fosamil 2,22 mg/ml
NaCl 0,9% or Glucose 5% 3249
Immediate precipitation Incompatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Ceftobiprole medocaril sodium 2 mg/ml
NaCl 0,9% or Glucose 5% 2269
Unspecified incompatibility Incompatible
Injection Metoclopramide hydrochloride
Injection Ceftobiprole medocaril sodium
4650
Immediate precipitation Incompatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Ceftobiprole medocaril sodium 2 mg/ml
Ringer’s lactate solution 2269
Compatible
Injection Metoclopramide hydrochloride 0.2 mg/ml
Injection Ceftolozane / tazobactam 10/5 mg/ml
NaCl 0,9% or Glucose 5% 3828
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Ciprofloxacin lactate 2 mg/ml
NaCl 0,9% or Glucose 5% 288
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Ciprofloxacin lactate 2 mg/ml
Sodium chloride 0,9% 289
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Cisatracurium besylate 0.1 >> 5 mg/ml
Glucose 5% 299
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Cladribine 0.015 mg/ml
Sodium chloride 0,9% 1496
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Cladribine 0.5 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Cloxacillin sodium 100 mg/ml
Water for Injection 3012
Compatible
Injection Metoclopramide hydrochloride 1.11 & 3.33 mg/ml
Injection Dexamethasone sodium phosphate 0.44 & 1.33 mg/ml
Sodium chloride 0,9% 1971
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Dexmedetomidine 4 µg/ml
Sodium chloride 0,9% 1712
Compatible
Injection Metoclopramide hydrochloride 0.16 >> 0.45 mg/ml
Injection Diamorphine hydrochloride 45.45 >> 145.16 mg/ml
None 1230
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Diltiazem hydrochloride 1 & 5 mg/ml
Sodium chloride 0,9% 198
Compatible
Injection Metoclopramide hydrochloride 0.2 mg/ml
Injection Diltiazem hydrochloride 5 mg/ml
Sodium chloride 0,9% 198
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Docetaxel 0.9 mg/ml
Glucose 5% 1754
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Doripenem 5 mg/ml
NaCl 0,9% or Glucose 5% 2262
Compatible
Injection Metoclopramide hydrochloride 1 mg/ml
Injection Doxapram hydrochloride 2 mg/ml
Glucose 5% 1802
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Doxorubicin hydrochloride 2 mg/ml
763
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Famotidine
Glucose 5% 397
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Parenteral nutrition (binary mixture) 3948
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Etoposide phosphate 5 mg/ml
Glucose 5% 1410
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Famotidine 2 mg/ml
Sodium chloride 0,9% 215
Compatible
Injection Metoclopramide hydrochloride 0.58 mg/ml
Parenteral nutrition (binary mixture) 3379
Loss of turbidity Incompatible
Injection Metoclopramide hydrochloride 5 mg/ml
Parenteral nutrition (binary mixture) 301
Immediate turbidity Incompatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Doxorubicin hydrochloride liposome peg 0.4 mg/ml
Glucose 5% 251
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Droperidol 2,5 mg/ml
763
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Parenteral nutrition (with lipids) 1415
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Fentanyl citrate 25 µg/ml
Glucose 5% 1974
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Filgrastim 30 µg/ml
Glucose 5% 244
Immediate precipitation Incompatible
Injection Metoclopramide hydrochloride 1 mg/ml
Injection Flucloxacillin sodium 20 mg/ml
Sodium chloride 0,9% 1232
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Fluconazole 2 mg/ml
Sodium chloride 0,9% 496
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Fludarabine phosphate 1 mg/ml
Glucose 5% 492
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Fluorouracil 50 mg/ml
763
Unspecified incompatibility Incompatible
Injection Metoclopramide hydrochloride
Injection Fluorouracil
3474
Compatible
Injection Metoclopramide hydrochloride 0,1 mg/ml
Injection Fluorouracil 2,5 mg/ml
Glucose 5% 153
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Folinate calcium 10 mg/ml
763
Compatible
Injection Metoclopramide hydrochloride 2 mg/ml
Injection Foscarnet sodium 24 mg/ml
NaCl 0,9% or Glucose 5% 1135
Compatible
Injection Metoclopramide hydrochloride 4 mg/ml
Injection Foscarnet sodium 24 mg/ml
None 73
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Ringer’s lactate solution 4603
Compatible
Injection Metoclopramide hydrochloride 0.2 mg/ml
Injection Fosfomycin 30 mg/ml
NaCl 0,9% or Glucose 5% 4055
Immediate precipitation Incompatible
Injection Metoclopramide hydrochloride 1 mg/ml
Injection Furosemide 1 mg/ml
Sodium chloride 0,9% 1232
Immediate precipitation Incompatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Furosemide 10 mg/ml
763
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Gallium nitrate 1 mg/ml
Sodium chloride 0,9% 91
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Gemcitabine hydrochloride 10 mg/ml
Sodium chloride 0,9% 1423
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Heparin sodium 1000 UI/ml
763
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Parenteral nutrition (with lipids) 3948
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Granisetron hydrochloride 0.05 mg/ml
Glucose 5% 182
Compatible
Injection Metoclopramide hydrochloride 1.11 & 3.33 mg/ml
Injection Haloperidol lactate 0.21 & 0.62 mg/ml
Sodium chloride 0,9% 1971
Compatible
Injection Metoclopramide hydrochloride 3 mg/ml
Injection Haloperidol lactate 0.25 >> 0.5 mg/ml
NaCl 0,9% or Glucose 5% 4404
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Hetastarch 60 mg/ml
Specific solvent 1721
Compatible
Injection Metoclopramide hydrochloride
Injection Hyaluronidase
3184
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Hydromorphone hydrochloride 0.5 mg/ml
Glucose 5% 1974
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Idarubicin hydrochloride 1 mg/ml
Sodium chloride 0,9% 491
Compatible
Injection Metoclopramide hydrochloride 1 mg/ml
Injection Imipenem-Cilastatin / Relebactam 5 mg/ml
NaCl 0,9% or Glucose 5% 4433
Compatible
Injection Metoclopramide hydrochloride 0.2 mg/ml
Injection Isavuconazonium sulfate 1.5 mg/ml
NaCl 0,9% or Glucose 5% 3829
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Ketamine hydrochloride 50 mg/ml
2109
Compatible
Injection Metoclopramide hydrochloride 0.2 mg/ml
Injection Ketoprofene 3.2 mg/ml
Sodium chloride 0,9% 1847
Precipitation after 4 hours Incompatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Lansoprazole 0.55 mg/ml
Sodium chloride 0,9% 1625
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Levofloxacine 5 mg/ml
Glucose 5% 1072
Compatible
Injection Metoclopramide hydrochloride 3 mg/ml
Injection Levomepromazine 0.625 >> 2.5 mg/ml
NaCl 0,9% or Glucose 5% 4404
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Linezolid 2 mg/ml
None 1925
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Melphalan 0.1 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Meropenem 50 mg/ml
Water for Injection 4319
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Meropenem 1 & 50 mg/ml
Sodium chloride 0,9% 266
Compatible
Injection Metoclopramide hydrochloride 0.1 mg/ml
Injection Meropenem 1 & 20 mg/ml
Sodium chloride 0,9% 266
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Methadone hydrochloride 1 mg/ml
Glucose 5% 1974
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Methotrexate sodium 25 mg/ml
763
Unspecified incompatibility Incompatible
Injection Metoclopramide hydrochloride
Injection Methotrexate sodium
3637
Compatible
Injection Metoclopramide hydrochloride 3.33 mg/ml
Injection Midazolam hydrochloride 1.67 mg/ml
None 404
Compatible
Injection Metoclopramide hydrochloride 3 mg/ml
Injection Midazolam hydrochloride 1.2 mg/ml
NaCl 0,9% or Glucose 5% 4404
Compatible
Injection Metoclopramide hydrochloride 1.11 & 3.33 mg/ml
Injection Midazolam hydrochloride 0.5 & 1.5 mg/ml
Sodium chloride 0,9% 1971
Compatible
Injection Metoclopramide hydrochloride 3 mg/ml
Injection Morphine hydrochloride 2 >> 5 mg/ml
NaCl 0,9% or Glucose 5% 4404
Compatible
Injection Metoclopramide hydrochloride 3.33 mg/ml
Injection Morphine hydrochloride 1.67 >> 10 mg/ml
Water for Injection 1757
Compatible
Injection Metoclopramide hydrochloride 1.11 & 3.33 mg/ml
Injection Morphine hydrochloride 1.68 & 5 mg/ml
Sodium chloride 0,9% 1971
Compatible
Injection Metoclopramide hydrochloride 0.2 mg/ml
Injection Morphine sulfate 1 mg/ml
Glucose 5% 62
Compatible
Injection Metoclopramide hydrochloride 0.5 mg/ml
Injection Morphine sulfate 1 mg/ml
NaCl 0,9% or Glucose 5% 1495
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Morphine sulfate 1 mg/ml
Glucose 5% 1974
Compatible
Injection Metoclopramide hydrochloride
Injection Morphine tartrate
519
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Naloxone hydrochloride 0.4 mg/ml
None 3408
Compatible
Injection Metoclopramide hydrochloride 2.5 mg/ml
Injection Ondansetron hydrochloride 1 mg/ml
Sodium chloride 0,9% 815
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Ondansetron hydrochloride 1 mg/ml
Sodium chloride 0,9% 334
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Oxaliplatin 0,5 mg/ml
Glucose 5% 1662
Compatible
Injection Metoclopramide hydrochloride 2.9 & 3.3 mg/ml
Injection Oxycodone hydrochloride 14.7 & 38.5 mg/ml
Water for Injection 2900
Compatible
Injection Metoclopramide hydrochloride 1.2 & 2.5 mg/ml
Injection Oxycodone hydrochloride 0.8 & 5 mg/ml
Water for Injection 2125
Compatible
Injection Metoclopramide hydrochloride 2.9 & 3.3 mg/ml
Injection Oxycodone hydrochloride 14.7 & 38.5 mg/ml
Sodium chloride 0,9% 2900
Compatible
Injection Metoclopramide hydrochloride 1.2 & 2.5 mg/ml
Injection Oxycodone hydrochloride 0.8 & 5 mg/ml
Sodium chloride 0,9% 2125
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Paclitaxel 1.2 mg/ml
Glucose 5% 85
Compatible
Injection Metoclopramide hydrochloride 50 mg/ml
Injection Palonosetron hydrochloride 50 µg/ml
None 2179
Precipitation after 15 minutes Incompatible
Injection Metoclopramide hydrochloride
Injection Pantoprazole sodium
2090
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Pemetrexed disodium 20 mg/ml
Sodium chloride 0,9% 1953
Compatible
Injection Metoclopramide hydrochloride 6.67 mg/ml
Injection Pethidine hydrochloride 16.67 mg/ml
None 930
Compatible
Injection Metoclopramide hydrochloride 0.15 mg/ml
Injection Pethidine hydrochloride 7.35 mg/ml
NaCl 0,9% or Glucose 5% 930
Compatible
Injection Metoclopramide hydrochloride 0.2 mg/ml
Injection Pethidine hydrochloride 10 mg/ml
Glucose 5% 62
Compatible
Injection Metoclopramide hydrochloride 1 mg/ml
Injection Phloroglucinol 2,5 mg/ml
3791
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Piperacillin sodium / tazobactam 40/5 mg/ml
Glucose 5% 81
Compatible
Injection Metoclopramide hydrochloride 0.2 mg/ml
Injection Plazomicin sulfate 24 mg/ml
Sodium chloride 0,9% 4145
Precipitation after 4 hours Incompatible
Injection Metoclopramide hydrochloride 0,1 mg/ml
Injection Posaconazole 1,2 mg/ml
Sodium chloride 0,9% 4521
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Propofol 10 mg/ml
None 300
Instability of the emulsion after 4 hours Incompatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Propofol
660
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Quinupristine/dalfopristine 2 mg/ml
Glucose 5% 1513
Compatible
Injection Metoclopramide hydrochloride 10 mg/ml
Injection Ranitidine hydrochloride 25 mg/ml
None 58
Compatible
Injection Metoclopramide hydrochloride 0,2 mg/ml
Injection Ranitidine hydrochloride 1 mg/ml
Sodium chloride 0,9% 3558
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Remifentanil hydrochloride 25 & 250 µg/ml
Sodium chloride 0,9% 59
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Salbutamol sulfate 1 mg/ml
None 3216
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Sargramostim 10 µg/ml
Sodium chloride 0,9% 335
Compatible
Injection Metoclopramide hydrochloride 3 mg/ml
Injection Scopolamine N-butyl bromide 3-7 mg/ml
NaCl 0,9% or Glucose 5% 4404
Compatible
Injection Metoclopramide hydrochloride 1.11 & 3.33 mg/ml
Injection Scopolamine N-butyl bromide 1.68 & 5 mg/ml
Sodium chloride 0,9% 1971
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Sugammadex 100 mg/ml
None 3372
Compatible
Injection Metoclopramide hydrochloride 0,2 mg/ml
Injection Tacrolimus 1000 µg/ml
Sodium chloride 0,9% 479
Compatible
Injection Metoclopramide hydrochloride 0.2 mg/ml
Injection Tedizolid phosphate 0.8 mg/ml
Sodium chloride 0,9% 3827
Compatible
Injection Metoclopramide hydrochloride 1 mg/ml
Injection Telavancin hydrochloride 7.5 mg/ml
NaCl 0,9% or Glucose 5% 3254
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Teniposide 0.1 mg/ml
Glucose 5% 905
Immediate precipitation Incompatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Thiopental sodium 25 mg/ml
Sodium chloride 0,9% 3767
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Thiotepa 1 mg/ml
Glucose 5% 249
Compatible
Injection Metoclopramide hydrochloride
Injection Tigecycline
Sodium chloride 0,9% 3332
Compatible
Injection Metoclopramide hydrochloride 1.72 mg/ml
Injection Topotecan 0.056 mg/ml
NaCl 0,9% or Glucose 5% 1026
Compatible
Injection Metoclopramide hydrochloride 0,1 mg/ml
Injection Tramadol hydrochloride 1 mg/ml
Glucose 5% 3082
Compatible
Injection Metoclopramide hydrochloride 1.11 & 3.33 mg/ml
Injection Tramadol hydrochloride 11.18 & 33.3 mg/ml
Sodium chloride 0,9% 1971
Compatible
Injection Metoclopramide hydrochloride 0.02 mg/ml
Injection Verapamil hydrochloride 0.08 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Vinblastine sulfate 1 mg/ml
763
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Vincristine sulfate 1 mg/ml
763
Compatible
Injection Metoclopramide hydrochloride 5 mg/ml
Injection Vinorelbine tartrate 1 mg/ml
Sodium chloride 0,9% 84
Compatible
Injection Metoclopramide hydrochloride 2 mg/ml
Injection Zidovudine 4 mg/ml
Glucose 5% 337

  Mentions Légales