Last update :
18/04/2024
Antiparasitic   Metronidazole  
Injection
Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Amrizole Egypt, Saudi Arabia, United Arab Emirates
Anaerobex Austria
Anaeromet Luxembourg
Antibactrol Chile
Bactrizol Venezuela
Colpocin Greece
Deflamon Italy
Dumozol Egypt, Portugal
Efloran Croatia, Slovenia
Elyzol Saudi Arabia
Emedal Greece
Femagin Malaysia
Flagyl Belgium, Brazil, Chile, Colombia, Denmark, Ecuador, Egypt, France, Great Britain, Greece, Iceland, Ireland, Morocco, Netherlands, Norway, Peru, Republic of South Africa, Spain, Sweden, Switzerland, Turkey, United States of America
Flaxtec Mexico
Flazol Egypt
Flegyl Venezuela
Gnostol Greece
Klion Hungary
Medazol Croatia
Metrolag Switzerland
Metrolyl Great Britain
Metronidazole Australia, Canada
Nidazol Turkey
Novakom Turkey
Compatibility   Injection   Compatibility : Metronidazole              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
Injection Metronidazole 5 mg/ml
Injection Aciclovir sodium 5 mg/ml
Glucose 5% 336
Compatible
Injection Metronidazole 5 mg/ml
Injection Allopurinol sodium 3 mg/ml
Sodium chloride 0,9% 307
Compatible
Injection Metronidazole 5 mg/ml
Injection Amifostine 10 mg/ml
Glucose 5% 3
Compatible
Injection Metronidazole
Injection Amikacin sulfate
3594
Compatible
Injection Metronidazole 5 mg/ml
Injection Amikacin sulfate 5 mg/ml
None 1035
Compatible
Injection Metronidazole 5 mg/ml
Injection Amiodarone hydrochloride 4 mg/ml
NaCl 0,9% or Glucose 5% 385
Compatible
Injection Metronidazole 5 mg/ml
Injection Amiodarone hydrochloride 6 mg/ml
Glucose 5% 1611
Compatible
Injection Metronidazole 5 mg/ml
Injection Amoxicillin sodium / clavulanic acid 100/10 mg/ml
3824
Immediate precipitation Incompatible
Injection Metronidazole 5 mg/ml
Injection Amphotericin B cholesteryl sulfate complex 0,83 mg/ml
Glucose 5% 921
Compatible
Injection Metronidazole
Injection Ampicillin sodium
3594
Compatible
Injection Metronidazole 5 mg/ml
Injection Ampicillin sodium 20 mg/ml
None 1035
Compatible
Injection Metronidazole 5 mg/ml
Injection Ampicillin sodium 20 mg/ml
None 631
Compatible
Injection Metronidazole 5 mg/ml
Injection Anidulafungin 0.5 mg/ml
Glucose 5% 1982
Immediate turbidity Incompatible
Injection Metronidazole 5 mg/ml
Injection Atenolol 0,1 mg/ml
Sodium chloride 0,9% 4698
Color change after 12 hours Incompatible
Injection Metronidazole 5 mg/ml
Injection Aztreonam 10 & 20 mg/ml
None 19
Unspecified incompatibility Incompatible
Injection Metronidazole
Injection Aztreonam
3547
Color change after 4 hours Incompatible
Injection Metronidazole 5 mg/ml
Injection Aztreonam 40 mg/ml
Glucose 5% 99
Compatible
Injection Metronidazole 5 mg/ml
Injection Bivalirudin 5 mg/ml
Glucose 5% 1713
Immediate precipitation Incompatible
Injection Metronidazole 2.5 mg/ml
Injection Blinatumomab 0.125 & 0.375 µg/ml
Sodium chloride 0,9% 3976
Compatible
Injection Metronidazole 5 mg/ml
Injection Caffeine 10 mg/ml
None 3964
Compatible
Injection Metronidazole 5 mg/ml
Injection Caspofungin acetate 0,7 mg/ml
Sodium chloride 0,9% 2247
Compatible
Injection Metronidazole 5 mg/ml
Injection Caspofungin acetate 0.5 mg/ml
Sodium chloride 0,9% 2233
Compatible
Injection Metronidazole
Injection Cefalotin sodium
3594
Compatible
Injection Metronidazole 5 mg/ml
Injection Cefalotin sodium 20 mg/ml
None 1035
Compatible
Injection Metronidazole 5 mg/ml
Injection Cefalotin sodium 20 mg/ml
None 631
Compatible
Injection Metronidazole 4.17 mg/ml
Injection Cefamandole nafate 16.67 mg/ml
None 1479
Chemical instability Incompatible
Injection Metronidazole 5 mg/ml
Injection Cefamandole nafate 20 mg/ml
None 1035
Unspecified incompatibility Incompatible
Injection Metronidazole
Injection Cefamandole nafate
3594
Compatible
Injection Metronidazole 5 mg/ml
Injection Cefazolin sodium 10 mg/ml
None 631
Compatible
Injection Metronidazole 5 mg/ml
Injection Cefazolin sodium 10 mg/ml
None 1035
Compatible
Injection Metronidazole
Injection Cefazolin sodium
3594
Unspecified incompatibility Incompatible
Injection Metronidazole
Injection Cefepime dihydrochloride
3548
Compatible
Injection Metronidazole 5 mg/ml
Injection Cefiderocol sulfate tosylate 20 mg/mL
NaCl 0,9% or Glucose 5% 4528
Compatible
Injection Metronidazole 5 mg/ml
Injection Cefotaxime sodium 10 mg/ml
None 281
Compatible
Injection Metronidazole
Injection Cefotaxime sodium
3594
Compatible
Injection Metronidazole 5 mg/ml
Injection Cefotaxime sodium 20 mg/ml
None 1035
Chemical instability Incompatible
Injection Metronidazole 5 mg/ml
Injection Cefoxitin sodium 30 mg/ml
None 1035
Compatible
Injection Metronidazole 5 mg/ml
Injection Cefoxitin sodium 30 mg/ml
None 631
Compatible
Injection Metronidazole 5 mg/ml
Injection Ceftobiprole medocaril sodium 2 mg/ml
Ringer’s lactate solution 2269
Compatible
Injection Metronidazole 5 mg/ml
Parenteral nutrition (with lipids) 1415
Unspecified incompatibility Incompatible
Injection Metronidazole
Injection Cefoxitin sodium
3594
Compatible
Injection Metronidazole 5 mg/ml
Injection Ceftobiprole medocaril sodium 2 mg/ml
NaCl 0,9% or Glucose 5% 2269
Compatible
Injection Metronidazole 5 mg/ml
Injection Ceftolozane / tazobactam 10/5 mg/ml
NaCl 0,9% or Glucose 5% 3828
Compatible
Injection Metronidazole 5 mg/ml
Ringer’s lactate solution 4603
Immediate turbidity Incompatible
Injection Metronidazole 5 mg/ml
Parenteral nutrition (with lipids) 4440
Compatible
Injection Metronidazole 5 mg/ml
Injection Ceftaroline fosamil 2,22 mg/ml
NaCl 0,9% or Glucose 5% 3249
Compatible
Injection Metronidazole 5 mg/ml
Parenteral nutrition (with lipids) 3967
Compatible
Injection Metronidazole 5 mg/ml
Injection Ceftaroline fosamil 2,22 mg/ml
Ringer’s lactate solution 3249
Compatible
Injection Metronidazole 5 mg/ml
Injection Ceftazidime 10 mg/ml
None 282
Compatible
Injection Metronidazole 5 mg/ml
Injection Ceftizoxime sodium 10 mg/ml
None 282
Compatible
Injection Metronidazole 5 mg/ml
Injection Ceftizoxime sodium 10 mg/ml
None 267
Compatible
Injection Metronidazole 5 mg/ml
Parenteral nutrition (with lipids) 3948
Compatible
Injection Metronidazole 5 mg/ml
Injection Ceftriaxone disodium 10 mg/ml
None 282
Compatible
Injection Metronidazole 7.5 mg/ml
Injection Ceftriaxone disodium 10 mg/ml
NaCl 0,9% or Glucose 5% 11
Compatible
Injection Metronidazole 5 mg/ml
Injection Ceftriaxone disodium 10 mg/ml
None 649
Immediate precipitation Incompatible
Injection Metronidazole 15 mg/ml
Injection Ceftriaxone disodium 20 mg/ml
NaCl 0,9% or Glucose 5% 11
Compatible
Injection Metronidazole
Injection Cefuroxime sodium
3594
Compatible
Injection Metronidazole 5 mg/ml
Injection Cefuroxime sodium 7,5 mg/ml
None 961
Compatible
Injection Metronidazole 5 mg/ml
Injection Chloramphenicol sodium succinate 10 mg/ml
None 1035
Compatible
Injection Metronidazole
Injection Chloramphenicol sodium succinate
3594
Compatible
Injection Metronidazole 2.5 mg/ml
Injection Ciprofloxacin lactate 2 mg/ml
Glucose 5% 285
Compatible
Injection Metronidazole 5 mg/ml
Injection Ciprofloxacin lactate 2 mg/ml
Sodium chloride 0,9% 289
Compatible
Injection Metronidazole 4 mg/ml
Injection Ciprofloxacin lactate 1.5 mg/ml
NaCl 0,9% or Glucose 5% 434
Compatible
Injection Metronidazole 5 mg/ml
Injection Cisatracurium besylate 0.1 >> 5 mg/ml
Glucose 5% 299
Compatible
Injection Metronidazole 5 mg/ml
Injection Clindamycin phosphate 10 mg/ml
None 1035
Compatible
Injection Metronidazole 5 mg/ml
Injection Cloxacillin sodium 100 mg/ml
Water for Injection 3012
Compatible
Injection Metronidazole
Injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
Sodium chloride 0,9% 4654
Unspecified incompatibility Incompatible
Injection Metronidazole
Glucose 10% 3594
Compatible
Injection Metronidazole 5 mg/ml
Parenteral nutrition (binary mixture) 301
Compatible
Injection Metronidazole
Injection Clindamycin phosphate
3594
Compatible
Injection Metronidazole 5 mg/ml
Injection Defibrotide 8 mg/ml
Sodium chloride 0,9% 3728
Compatible
Injection Metronidazole 5 & 8 mg/ml
Injection Diltiazem hydrochloride 5 mg/ml
Sodium chloride 0,9% 198
Compatible
Injection Metronidazole
Injection Dimenhydrinate
2087
Compatible
Injection Metronidazole 5 mg/ml
Parenteral nutrition (binary mixture) 939
Compatible
Injection Metronidazole 5 mg/ml
Parenteral nutrition (binary mixture) 3948
Compatible
Injection Metronidazole 5 mg/ml
Injection Dexmedetomidine 4 µg/ml
Sodium chloride 0,9% 1712
Compatible
Injection Metronidazole 5 mg/ml
Parenteral nutrition (binary mixture) 316
Compatible
Injection Metronidazole 5 mg/ml
Injection Docetaxel 0.9 mg/ml
Glucose 5% 1754
Compatible
Injection Metronidazole 5 mg/ml
Injection Dopamine hydrochloride 0.8 mg/ml
Glucose 5% 132
Compatible
Injection Metronidazole 5 mg/ml
Injection Doripenem 5 mg/ml
NaCl 0,9% or Glucose 5% 2262
Compatible
Injection Metronidazole 5 mg/ml
Injection Doxapram hydrochloride 2 mg/ml
Glucose 5% 1802
Compatible
Injection Metronidazole 5 mg/ml
Injection Doxorubicin hydrochloride liposome peg 0.4 mg/ml
Glucose 5% 251
Compatible
Injection Metronidazole 5 mg/ml
Injection Enalaprilate 0.05 mg/ml
Sodium chloride 0,9% 1315
Compatible
Injection Metronidazole 5 mg/ml
Injection Eravacycline 0,6 mg/ml
Sodium chloride 0,9% 4434
Compatible
Injection Metronidazole 5 mg/ml
Injection Esmolol hydrochloride 10 mg/ml
Glucose 5% 384
Compatible
Injection Metronidazole 5 mg/ml
Injection Etoposide phosphate 5 mg/ml
Glucose 5% 1410
Compatible
Injection Metronidazole 5 mg/ml
Injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Compatible
Injection Metronidazole 5 mg/ml
Injection Fentanyl citrate 50 µg/ml
Glucose 5% 63
Immediate precipitation Incompatible
Injection Metronidazole 5 mg/ml
Injection Filgrastim 30 µg/ml
Glucose 5% 244
Compatible
Injection Metronidazole 5 mg/ml
Injection Fluconazole 2 mg/ml
Sodium chloride 0,9% 496
Compatible
Injection Metronidazole 5 mg/ml
Injection Fluconazole 2 mg/ml
None 256
Compatible
Injection Metronidazole 5 mg/ml
Injection Foscarnet sodium 24 mg/ml
None 73
Compatible
Injection Metronidazole 5 mg/ml
Injection Foscarnet sodium 24 mg/ml
Sodium chloride 0,9% 1135
Compatible
Injection Metronidazole 5 mg/ml
Injection Fosfomycin 30 mg/ml
NaCl 0,9% or Glucose 5% 4055
Compatible
Injection Metronidazole 5 mg/ml
Injection Gemcitabine hydrochloride 10 mg/ml
Sodium chloride 0,9% 1423
Compatible
Injection Metronidazole 5 mg/ml
Injection Gentamicin sulfate 0,8 & 1,2 mg/ml
None 1243
Compatible
Injection Metronidazole
Injection Gentamicin sulfate
3594
Compatible
Injection Metronidazole 5 mg/ml
Injection Gentamicin sulfate 0.8 mg/ml
None 1035
Compatible
Injection Metronidazole 5 mg/ml
Injection Granisetron hydrochloride 0.05 mg/ml
Glucose 5% 182
Compatible
Injection Metronidazole 5 mg/ml
Injection Heparin sodium 50 UI/ml
None 317
Compatible
Injection Metronidazole 5 mg/ml
Injection Hetastarch 60 mg/ml
Specific solvent 1721
Compatible
Injection Metronidazole 5 mg/ml
Injection Hydrocortisone sodium succinate 10 mg/ml
None 631
Compatible
Injection Metronidazole 5 mg/ml
Injection Hydrocortisone sodium succinate 10 mg/ml
None 1035
Compatible
Injection Metronidazole
Injection Hydrocortisone sodium succinate
3594
Compatible
Injection Metronidazole 5 mg/ml
Injection Hydromorphone hydrochloride 0.2 mg/ml
Glucose 5% 405
Compatible
Injection Metronidazole 5 mg/ml
Injection Ketamine hydrochloride 50 mg/ml
2109
Compatible
Injection Metronidazole 5 mg/ml
Injection Labetalol hydrochloride 1 mg/ml
Glucose 5% 386
Immediate turbidity Incompatible
Injection Metronidazole 5 mg/ml
Injection Lansoprazole 0.55 mg/ml
Sodium chloride 0,9% 1625
Compatible
Injection Metronidazole 5 mg/ml
Injection Levofloxacine 5 mg/ml
None 1988
Compatible
Injection Metronidazole 5 mg/ml
Injection Linezolid 2 mg/ml
None 1925
Compatible
Injection Metronidazole 5 mg/ml
Injection Lorazepam 0.33 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Metronidazole 2 mg/ml
Injection Magnesium sulfate 10 & 20 mg/ml
Glucose 5% 630
Compatible
Injection Metronidazole 5 mg/ml
Injection Magnesium sulfate 16.67 >> 100 mg/ml
Glucose 5% 1047
Compatible
Injection Metronidazole 5 mg/ml
Injection Melphalan 0.1 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Metronidazole 5 mg/ml
Injection Meropenem 1 >> 50 mg/ml
Sodium chloride 0,9% 266
Compatible
Injection Metronidazole 5 mg/ml
Injection Meropenem 50 mg/ml
Water for Injection 4319
Compatible
Injection Metronidazole 5 mg/ml
Injection Methylprednisolone sodium succinate 5 mg/ml
Glucose 5% 132
Compatible
Injection Metronidazole 5 mg/ml
Injection Midazolam hydrochloride 1 mg/ml
Glucose 5% 176
Compatible
Injection Metronidazole 5 mg/ml
Injection Midazolam hydrochloride 5 mg/ml
None 186
Compatible
Injection Metronidazole 5 mg/ml
Injection Midazolam hydrochloride 0.05 >> 0.4 mg/ml
None 1888
Compatible
Injection Metronidazole 5 mg/ml
Injection Morphine sulfate 1 mg/ml
Glucose 5% 405
Compatible
Injection Metronidazole 5 mg/ml
Injection Moxalactam 20 mg/ml
None 631
Compatible
Injection Metronidazole 5 mg/ml
Injection Moxalactam 20 mg/ml
None 1035
Unspecified incompatibility Incompatible
Injection Metronidazole 5 mg/ml
Injection N-acetylcysteine 200 mg/ml
None 3766
Compatible
Injection Metronidazole 5 mg/ml
Injection Naloxone hydrochloride 0.4 mg/ml
None 3408
Compatible
Injection Metronidazole 5 mg/ml
Injection Netilmicin sulfate 1 mg/ml
Sodium chloride 0,9% 958
Compatible
Injection Metronidazole
Injection Netilmicin sulfate
3594
Compatible
Injection Metronidazole 5 mg/ml
Injection Netilmicin sulfate 1.4 mg/ml
None 1035
Compatible
Injection Metronidazole 5 mg/ml
Injection Nicardipine hydrochloride 0.1 mg/ml
NaCl 0,9% or Glucose 5% 1490
Immediate precipitation Incompatible
Injection Metronidazole 5 mg/ml
Injection Oritavancin 2 mg/ml
Glucose 5% 3152
Compatible
Injection Metronidazole 5 mg/ml
Injection Oritavancin 0.8 >>1.2 mg/ml
Glucose 5% 3152
Compatible
Injection Metronidazole 5 mg/ml
Injection Palonosetron hydrochloride 50 µg/ml
Glucose 5% 2228
Precipitation after 15 minutes Incompatible
Injection Metronidazole
Injection Pantoprazole sodium
2090
Compatible
Injection Metronidazole 5 mg/ml
Injection Paracetamol 10 mg/ml
4742
Color change Incompatible
Injection Metronidazole 5 mg/ml
Injection Pemetrexed disodium 20 mg/ml
Sodium chloride 0,9% 1953
Compatible
Injection Metronidazole 5 mg/ml
Injection Penicillin G potassium 0.2 MUI/ml
None 631
Chemical instability Incompatible
Injection Metronidazole 5 mg/ml
Injection Penicillin G potassium 0.012 MUI/ml
None 1035
Unspecified incompatibility Incompatible
Injection Metronidazole
Injection Penicillin G potassium
3594
Compatible
Injection Metronidazole 5 mg/ml
Injection Pentoxifyllin 5 mg/ml
Sodium chloride 0,9% 4543
Compatible
Injection Metronidazole 5 mg/ml
Injection Pethidine hydrochloride 10 mg/ml
Glucose 5% 405
Compatible
Injection Metronidazole 2,5 mg/ml
Injection Phloroglucinol 2,5 mg/ml
3791
Compatible
Injection Metronidazole 5 mg/ml
Injection Piperacillin sodium 40 mg/ml
None 1692
Compatible
Injection Metronidazole 5 mg/ml
Injection Piperacillin sodium / tazobactam 40/5 mg/ml
Glucose 5% 81
Compatible
Injection Metronidazole 5 mg/ml
Injection Plazomicin sulfate 24 mg/ml
Sodium chloride 0,9% 4145
Compatible
Injection Metronidazole 5 mg/ml
Injection Remifentanil hydrochloride 25 & 250 µg/ml
Sodium chloride 0,9% 59
Compatible
Injection Metronidazole 5 mg/ml
Injection Salbutamol sulfate 1 mg/ml
None 3216
Compatible
Injection Metronidazole 5 mg/ml
Injection Sargramostim 10 µg/ml
Sodium chloride 0,9% 335
Compatible
Injection Metronidazole 5 mg/ml
Injection Tacrolimus 1000 µg/ml
Sodium chloride 0,9% 479
Compatible
Injection Metronidazole 5 mg/ml
Injection Tedizolid phosphate 0.8 mg/ml
Sodium chloride 0,9% 3827
Compatible
Injection Metronidazole 5 mg/ml
Injection Teniposide 0.1 mg/ml
Glucose 5% 905
Compatible
Injection Metronidazole 5 mg/ml
Injection Theophylline 4 mg/ml
None 317
Immediate precipitation Incompatible
Injection Metronidazole 5 mg/ml
Injection Thiopental sodium 25 mg/ml
Sodium chloride 0,9% 3767
Compatible
Injection Metronidazole 5 mg/ml
Injection Thiotepa 1 mg/ml
Glucose 5% 249
Compatible
Injection Metronidazole 5 mg/ml
Injection Tobramycin sulfate 0.8 mg/ml
None 1035
Compatible
Injection Metronidazole
Injection Tobramycin sulfate
3594
Compatible
Injection Metronidazole 5 mg/ml
Injection Vasopressin 0.2 UI/ml
Sodium chloride 0,9% 2017
Compatible
Injection Metronidazole 5 mg/ml
Injection Vinorelbine tartrate 1 mg/ml
Sodium chloride 0,9% 84
Turbidity in 24 hours Incompatible
Injection Metronidazole 5 mg/ml
Injection Warfarin sodium 2 mg/ml
Glucose 5% 315

  Mentions Légales