Last update :
18/04/2024
Antibiotic   Piperacillin sodium  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Avocin Italy
Cilpier Italy
Diperil Italy
Ecosette Italy
Farecillin Italy
Ivacin Denmark
Pentcillin Japan
Peracil Italy
Pipcil Netherlands
Pipera Germany
Piperacillin Australia, Canada, Germany, Poland, United States of America
Piperacilline France, Greece, Tunisia
Piperital Italy
Pipertex Italy
Pipracil Egypt
Pipril Colombia, Denmark, Greece, United Arab Emirates
Semipenil Italy
Compatibility   Injection   Compatibility : Piperacillin sodium              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
Injection Piperacillin sodium 60 mg/ml
Injection Aciclovir sodium 5 mg/ml
Glucose 5% 336
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Allopurinol sodium 3 mg/ml
Sodium chloride 0,9% 307
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Amifostine 10 mg/ml
Glucose 5% 3
Immediate precipitation Incompatible
Injection Piperacillin sodium 60 mg/ml
Injection Amiodarone hydrochloride 6 mg/ml
Glucose 5% 1611
Immediate precipitation Incompatible
Injection Piperacillin sodium 40 mg/ml
Injection Amphotericin B cholesteryl sulfate complex 0.83 mg/ml
Glucose 5% 921
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Aztreonam 40 mg/ml
Glucose 5% 99
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Bivalirudin 5 mg/ml
Glucose 5% 1713
Precipitation after 24 hours Incompatible
Injection Piperacillin sodium 40 mg/ml
Injection Ciprofloxacin lactate 2 mg/ml
Glucose 5% 285
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Cisatracurium besylate 0.1 mg/ml
Glucose 5% 299
Immediate turbidity Incompatible
Injection Piperacillin sodium 40 mg/ml
Injection Cisatracurium besylate 2 & 5 mg/ml
Glucose 5% 299
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Dexmedetomidine 4 µg/ml
Sodium chloride 0,9% 1712
Compatible
Injection Piperacillin sodium 200 mg/ml
Injection Diltiazem hydrochloride 1 & 5 mg/ml
Sodium chloride 0,9% 198
Compatible
Injection Piperacillin sodium 20 mg/ml
Injection Diltiazem hydrochloride 5 mg/ml
Sodium chloride 0,9% 198
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Doxorubicin hydrochloride liposome peg 0.4 mg/ml
Glucose 5% 251
Compatible
Injection Piperacillin sodium 12 mg/ml
Injection Enalaprilate 0.05 mg/ml
Sodium chloride 0,9% 1315
Compatible
Injection Piperacillin sodium 30 mg/ml
Injection Esmolol hydrochloride 10 mg/ml
Glucose 5% 384
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Etoposide phosphate 5 mg/ml
Glucose 5% 1410
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Famotidine 2 mg/ml
Sodium chloride 0,9% 215
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Famotidine
Glucose 5% 397
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Immediate precipitation Incompatible
Injection Piperacillin sodium 40 mg/ml
Injection Filgrastim 30 µg/ml
Glucose 5% 244
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Fludarabine phosphate 1 mg/ml
Glucose 5% 492
Compatible
Injection Piperacillin sodium 100 mg/ml
Injection Gallium nitrate 1 mg/ml
Sodium chloride 0,9% 91
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Heparin sodium 10 & 5000 UI/ml
Sodium chloride 0,9% 2037
Compatible
Injection Piperacillin sodium 200 mg/ml
Ringer’s lactate solution 4603
Compatible
Injection Piperacillin sodium 200 mg/ml
Injection Caffeine 10 mg/ml
None 3964
Subvisual incompatibility Incompatible
Injection Piperacillin sodium 300 mg/ml
Injection Cloxacillin sodium 100 mg/ml
Water for Injection 3012
Unspecified incompatibility Incompatible
Injection Piperacillin sodium
NaHCO3 3590
Chemical instability Incompatible
Injection Piperacillin sodium
Injection Amikacin sulfate
3549
Unspecified incompatibility Incompatible
Injection Piperacillin sodium
Injection Ciprofloxacin lactate
3529
Compatible
Injection Piperacillin sodium 40 mg/ml
Parenteral nutrition (binary mixture) 301
Compatible
Injection Piperacillin sodium 200 mg/ml
Parenteral nutrition (binary mixture) 999
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Ciprofloxacin lactate 1 mg/ml
NaCl 0,9% or Glucose 5% 500
Compatible
Injection Piperacillin sodium
Injection Clindamycin phosphate
NaCl 0,9% or Glucose 5% 3526
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Clindamycin phosphate 9 mg/ml
NaCl 0,9% or Glucose 5% 432
Compatible
Injection Piperacillin sodium
Injection Dimenhydrinate
2087
Chemical instability Incompatible
Injection Piperacillin sodium 2 mg/ml
Parenteral nutrition (binary mixture) 1103
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Docetaxel 0.9 mg/ml
Glucose 5% 1754
Compatible
Injection Piperacillin sodium 80 mg/ml
Injection Enalaprilate 0.025 mg/ml
Water for Injection 1703
Unspecified incompatibility Incompatible
Injection Piperacillin sodium
Injection Erythromycin lactobionate
3674
Compatible
Injection Piperacillin sodium 80 mg/ml
Injection Fluconazole 2 mg/ml
None 256
Compatible
Injection Piperacillin sodium 80 mg/ml
Injection Foscarnet sodium 24 mg/ml
None 73
Immediate turbidity Incompatible
Injection Piperacillin sodium 40 mg/ml
Injection Gemcitabine hydrochloride 10 mg/ml
Sodium chloride 0,9% 1423
Unspecified incompatibility Incompatible
Injection Piperacillin sodium
Injection Gentamicin sulfate
3643
Unspecified incompatibility Incompatible
Injection Piperacillin sodium
Injection Gentamicin sulfate
3520
Compatible
Injection Piperacillin sodium 60 mg/ml
Injection Heparin sodium 50 UI/ml
None 317
Compatible
Injection Piperacillin sodium 40 mg/ml
Parenteral nutrition (with lipids) 1415
Immediate precipitation Incompatible
Injection Piperacillin sodium 80 mg/ml
Injection Fluconazole 2 mg/ml
Sodium chloride 0,9% 496
Compatible
Injection Piperacillin sodium 10 mg/ml
Parenteral nutrition (with lipids) 4440
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Granisetron hydrochloride 0.05 mg/ml
Glucose 5% 182
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Hetastarch 60 mg/ml
Specific solvent 1721
Compatible
Injection Piperacillin sodium 60 mg/ml
Injection Hydromorphone hydrochloride 0.2 mg/ml
Glucose 5% 405
Unspecified incompatibility Incompatible
Injection Piperacillin sodium 200 mg/ml
Injection Ketamine hydrochloride 50 mg/ml
2109
Compatible
Injection Piperacillin sodium 200 mg/ml
Injection Ketamine hydrochloride 50 mg/ml
4389
Compatible
Injection Piperacillin sodium 10 mg/ml
Injection Labetalol hydrochloride 1 mg/ml
Glucose 5% 386
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Lansoprazole 0.55 mg/ml
Sodium chloride 0,9% 1625
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Linezolid 2 mg/ml
None 1925
Compatible
Injection Piperacillin sodium 30 mg/ml
Injection Linezolid 2 mg/ml
None 1658
Compatible
Injection Piperacillin sodium 150 mg/ml
Injection Lorazepam 0.33 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Piperacillin sodium 60 mg/ml
Injection Magnesium sulfate 16.67 >> 100 mg/ml
Glucose 5% 1047
Compatible
Injection Piperacillin sodium 5 mg/ml
Injection Magnesium sulfate 10 & 20 mg/ml
Glucose 5% 630
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Melphalan 0.1 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Piperacillin sodium 200 mg/ml
Injection Meropenem 50 mg/ml
Water for Injection 4319
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Metronidazole 5 mg/ml
None 1692
Compatible
Injection Piperacillin sodium 150 mg/ml
Injection Midazolam hydrochloride 5 mg/ml
None 186
Compatible
Injection Piperacillin sodium 60 mg/ml
Injection Morphine sulfate 1 mg/ml
Glucose 5% 405
Compatible
Injection Piperacillin sodium
Injection N-acetylcysteine 200 mg/ml
None 3766
Compatible
Injection Piperacillin sodium 200 mg/ml
Injection Naloxone hydrochloride 0.4 mg/ml
None 3408
Compatible
Injection Piperacillin sodium 12 mg/ml
Injection Nicardipine hydrochloride 0.1 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Piperacillin sodium 20 mg/ml
Injection Ofloxacin 2 mg/ml
None 889
Turbidity in 30 minutes Incompatible
Injection Piperacillin sodium 40 mg/ml
Injection Ondansetron hydrochloride 1 mg/ml
Sodium chloride 0,9% 334
Compatible
Injection Piperacillin sodium
Injection Pantoprazole sodium
2090
Compatible
Injection Piperacillin sodium 60 mg/ml
Injection Pethidine hydrochloride 10 mg/ml
Glucose 5% 405
Compatible
Injection Piperacillin sodium 50 mg/ml
Injection Phloroglucinol 2,5 mg/ml
3791
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Propofol 10 mg/ml
None 300
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Remifentanil hydrochloride 25 & 250 µg/ml
Sodium chloride 0,9% 59
Immediate precipitation Incompatible
Injection Piperacillin sodium 200 mg/ml
Injection Salbutamol sulfate 1 mg/ml
None 3216
Precipitation after 4 hours Incompatible
Injection Piperacillin sodium 40 mg/ml
Injection Sargramostim 10 µg/ml
Sodium chloride 0,9% 335
Unspecified incompatibility Incompatible
Injection Piperacillin sodium
Injection Sodium bicarbonate
3590
Compatible
Injection Piperacillin sodium 80 mg/ml
Injection Tacrolimus 1000 µg/ml
Sodium chloride 0,9% 479
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Teniposide 0.1 mg/ml
Glucose 5% 905
Compatible
Injection Piperacillin sodium 60 mg/ml
Injection Theophylline 4 mg/ml
None 317
Immediate precipitation Incompatible
Injection Piperacillin sodium 200 mg/ml
Injection Thiopental sodium 25 mg/ml
Sodium chloride 0,9% 3767
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Thiotepa 1 mg/ml
Glucose 5% 249
Chemical instability Incompatible
Injection Piperacillin sodium
Injection Tobramycin sulfate
1168
Immediate precipitation Incompatible
Injection Piperacillin sodium 10 >> 250 mg/ml
Injection Vancomycin hydrochloride 20 mg/ml
Glucose 5% 1674
Compatible
Injection Piperacillin sodium 1 >> 200 mg/ml
Injection Vancomycin hydrochloride 2 mg/ml
Glucose 5% 1674
Compatible
Injection Piperacillin sodium 1 mg/ml
Injection Vancomycin hydrochloride 20 mg/ml
Glucose 5% 1674
Compatible
Injection Piperacillin sodium 40 mg/ml
Injection Verapamil hydrochloride 2.5 mg/ml
NaCl 0,9% or Glucose 5% 371
Immediate precipitation Incompatible
Injection Piperacillin sodium 40 mg/ml
Injection Vinorelbine tartrate 1 mg/ml
Sodium chloride 0,9% 84
Compatible
Injection Piperacillin sodium 4 mg/ml
Injection Zidovudine 4 mg/ml
Glucose 5% 337

  Mentions Légales