Last update :
21/09/2021
Analgesic   Hydromorphone hydrochloride  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Dilaudid Canada, United States of America
Hydal Austria
Palladon Denmark, Switzerland
Palladone Great Britain
Stability in solutions   Injection   Stability in solutions : Hydromorphone hydrochloride     
Container Solvent Concentration Temperature Storage Length of time References
Glass Not specified 50 mg/ml 37°C Protect from light
90 Day
2305
Polyvinyl chloride NaCl 0,9% or Glucose 5% 1 & 5 mg/ml 23°C Not specified
42 Day
120
Polyvinyl chloride NaCl 0,9% or Glucose 5% 1 & 5 mg/ml 4°C Protect from light
42 Day
120
Polyvinyl chloride Sodium chloride 0,9% 0,2 & 10 mg/ml 23°C Not specified
90 Day
4230
Level of evidence A

Polyolefine Sodium chloride 0,9% 0,2 & 10 mg/ml 23°C Not specified
90 Day
4230
Level of evidence A

Not specified Sodium chloride 0,9% 0,2 mg/ml 20°C With or without light
112 Day
2659
Not specified Sodium chloride 0,9% 0,2 mg/ml 35°C Protect from light
112 Day
2659
Not specified Sodium chloride 0,9% 0,2 mg/ml 5°C Protect from light
112 Day
2659
Not specified None 10 mg/ml 37°C Protect from light
120 Day
1867
Polypropylen Syringe Sodium chloride 0,9% 0,1 mg/ml 25°C Not specified
100 Day
4303
Level of evidence A

Polypropylen Syringe Sodium chloride 0,9% 0,1 mg/ml 30°C Not specified
30 Day
5
Level of evidence B

Polypropylen Syringe Sodium chloride 0,9% 1,5 & 80 mg/ml 23°C Light
60 Day
1706
Polypropylen Syringe Sodium chloride 0,9% 1,5 & 80 mg/ml 37°C Protect from light
48 Hour
1706
Polypropylen Syringe Sodium chloride 0,9% 1,5 & 80 mg/ml 4°C Protect from light
60 Day
1706
Polypropylen Syringe None 10 mg/ml 30°C Not specified
30 Day
5
Level of evidence B


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