Last update :
17/04/2024
Antibiotic   Cefotaxime sodium  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Alvim Mexico
Antadar Portugal
Aximad Italy
Batixim Italy
Betaksim Turkey
Biotaksym Poland
Cefotax Brazil, Romania
Cefotaxim Germany
Ceftax Saudi Arabia
Centiax Italy
Claforan Austria, Belgium, Brazil, Canada, Denmark, Egypt, Finland, France, Germany, Greece, Hungary, Italy, Morocco, Netherlands, Russian, Saudi Arabia, Spain, Sweden, Switzerland, Thailand, Turkey, Venezuela
Clafotax Saudi Arabia
Letynol Greece
Lirgosin Italy
Molelant Greece
Naspor Greece
Phacocef Greece
Primocef Saudi Arabia
Ralopar Portugal
Rantaksyn Poland
Refotax Italy
Salocef Italy
Sefotak Turkey
Spectrocef Italy
Spirosine Greece
Stoparen Greece
Tarcefoksym Poland
Taxocef Turkey
Tirotax Poland
Totam Republic of South Africa, Saudi Arabia
Zariviz Italy
Compatibility   Injection   Compatibility : Cefotaxime sodium              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Aciclovir sodium 5 mg/ml
Glucose 5% 336
Immediate precipitation Incompatible
Injection Cefotaxime sodium 20 mg/ml
Injection Allopurinol sodium 3 mg/ml
Sodium chloride 0,9% 307
Compatible
Injection Cefotaxime sodium 100 mg/ml
Injection Alprostadil 15 µg/ml
3201
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Amifostine 10 mg/ml
Glucose 5% 3
Chemical instability Incompatible
Injection Cefotaxime sodium
Injection Amikacin sulfate
3549
Compatible
Injection Cefotaxime sodium 40 mg/ml
Injection Amiodarone hydrochloride 9 mg/ml
Glucose 5% 4698
Compatible
Injection Cefotaxime sodium 100 mg/ml
Injection Amoxicillin sodium / clavulanic acid 100/10 mg/ml
3824
Precipitation after 1 hour Incompatible
Injection Cefotaxime sodium
Injection Amphotericin B
Sodium chloride 0,9% 3871
Immediate precipitation Incompatible
Injection Cefotaxime sodium 200 mg/ml
Injection Azithromycine 2 mg/ml
Sodium chloride 0,9% 1800
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Aztreonam 40 mg/ml
Glucose 5% 99
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Bivalirudin 5 mg/ml
Glucose 5% 1713
Compatible
Injection Cefotaxime sodium 100 mg/ml
Injection Caffeine 10 mg/ml
None 3964
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Cisatracurium besylate 0.1 mg/ml
Glucose 5% 299
Immediate turbidity Incompatible
Injection Cefotaxime sodium 20 mg/ml
Injection Cisatracurium besylate 5 mg/ml
Glucose 5% 299
Turbidity in 4 hours Incompatible
Injection Cefotaxime sodium 20 mg/ml
Injection Cisatracurium besylate 2 mg/ml
Glucose 5% 299
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Clindamycin phosphate 9 mg/ml
NaCl 0,9% or Glucose 5% 421
Compatible
Injection Cefotaxime sodium
Injection Clindamycin phosphate
NaCl 0,9% or Glucose 5% 3526
Compatible
Injection Cefotaxime sodium 95 mg/ml
Injection Cloxacillin sodium 100 mg/ml
Water for Injection 3012
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Dexmedetomidine 4 µg/ml
Sodium chloride 0,9% 1712
Compatible
Injection Cefotaxime sodium 10 & 180 mg/ml
Injection Diltiazem hydrochloride 1 & 5 mg/ml
Sodium chloride 0,9% 198
Compatible
Injection Cefotaxime sodium
Injection Dimenhydrinate
2087
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Docetaxel 0.9 mg/ml
Glucose 5% 1754
Unspecified incompatibility Incompatible
Injection Cefotaxime sodium
Injection Erythromycin lactobionate
3674
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Etoposide phosphate 5 mg/ml
Glucose 5% 1410
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Famotidine 2 mg/ml
Sodium chloride 0,9% 215
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Famotidine
Glucose 5% 397
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Fentanyl citrate 50 µg/ml
Glucose 5% 63
Precipitation after 4 hours Incompatible
Injection Cefotaxime sodium 20 mg/ml
Injection Filgrastim 30 µg/ml
Glucose 5% 244
Turbidity in one hour Incompatible
Injection Cefotaxime sodium 20 mg/ml
Injection Fluconazole 2 mg/ml
Sodium chloride 0,9% 496
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Fludarabine phosphate 1 mg/ml
Glucose 5% 492
Turbidity in one hour Incompatible
Injection Cefotaxime sodium 20 mg/ml
Injection Gemcitabine hydrochloride 10 mg/ml
Sodium chloride 0,9% 1423
Unspecified incompatibility Incompatible
Injection Cefotaxime sodium
Injection Gentamicin sulfate
3520
Unspecified incompatibility Incompatible
Injection Cefotaxime sodium
Injection Gentamicin sulfate
3643
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Granisetron hydrochloride 0.05 mg/ml
Glucose 5% 182
Compatible
Injection Cefotaxime sodium 41.6 & 125 mg/ml
Injection Heparin sodium 208 UI/ml
NaCl 0,9% or Glucose 5% 4254
Compatible
Injection Cefotaxime sodium 10 mg/ml
Injection Heparin sodium 5000 UI/ml
Water for Injection 3125
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Hetastarch 60 mg/ml
Specific solvent 1721
Immediate precipitation Incompatible
Injection Cefotaxime sodium 20 mg/ml
Injection Hetastarch 60 mg/ml
Sodium chloride 0,9% 472
Turbidity in one hour Incompatible
Injection Cefotaxime sodium 83.3 mg/ml
Injection Hydrocortisone sodium succinate 2 mg/ml
NaCl 0,9% or Glucose 5% 4254
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Hydromorphone hydrochloride 0.2 mg/ml
Glucose 5% 405
Compatible
Injection Cefotaxime sodium 83.3 mg/ml
Injection Insulin 1 UI/ml
NaCl 0,9% or Glucose 5% 4254
Compatible
Injection Cefotaxime sodium 100 mg/ml
Ringer’s lactate solution 4603
Compatible
Injection Cefotaxime sodium 20 mg/ml
Parenteral nutrition (with lipids) 1415
Compatible
Injection Cefotaxime sodium 60 mg/ml
Parenteral nutrition (binary mixture) 316
Compatible
Injection Cefotaxime sodium 100 mg/ml
Injection Ketamine hydrochloride 50 mg/ml
2109
Compatible
Injection Cefotaxime sodium 200 mg/ml
Injection Levofloxacine 5 mg/ml
Glucose 5% 1072
Compatible
Injection Cefotaxime sodium 300 mg/ml
Parenteral nutrition (binary mixture) 999
Compatible
Injection Cefotaxime sodium 200 mg/ml
Parenteral nutrition (binary mixture) 939
Compatible
Injection Cefotaxime sodium 20 mg/ml
Parenteral nutrition (binary mixture) 301
Compatible
Injection Cefotaxime sodium 83.3 mg/ml
Injection Levetiracetam 20.83 mg/ml
NaCl 0,9% or Glucose 5% 4254
Compatible
Injection Cefotaxime sodium 10 mg/ml
Injection Lorazepam 0.33 mg/ml
Sodium chloride 0,9% 186
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Magnesium sulfate 16.67 >> 100 mg/ml
Glucose 5% 1047
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Melphalan 0.1 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Cefotaxime sodium 100 mg/ml
Injection Meropenem 50 mg/ml
Water for Injection 4319
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Metronidazole 5 mg/ml
None 1035
Compatible
Injection Cefotaxime sodium
Injection Metronidazole
3594
Compatible
Injection Cefotaxime sodium 10 mg/ml
Injection Metronidazole 5 mg/ml
None 281
Compatible
Injection Cefotaxime sodium 10 mg/ml
Injection Midazolam hydrochloride 5 mg/ml
None 186
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Midazolam hydrochloride 1 mg/ml
Glucose 5% 176
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Morphine sulfate 1 mg/ml
Glucose 5% 405
Compatible
Injection Cefotaxime sodium
Injection N-acetylcysteine 200 mg/ml
None 3766
Compatible
Injection Cefotaxime sodium 100 mg/ml
Injection Naloxone hydrochloride 0.4 mg/ml
None 3408
Immediate turbidity Incompatible
Injection Cefotaxime sodium 40 mg/ml
Injection Nefopam 0,16 mg/ml
Sodium chloride 0,9% 4698
Precipitation after 4 hours Incompatible
Injection Cefotaxime sodium
Injection Omeprazole sodium
Glucose 5% 3871
Precipitation after 4 hours Incompatible
Injection Cefotaxime sodium
Injection Omeprazole sodium
Sodium chloride 0,9% 3871
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Ondansetron hydrochloride 1 mg/ml
Sodium chloride 0,9% 334
Compatible
Injection Cefotaxime sodium 83.3 mg/ml
Injection Ornidazole 31.25 mg/ml
NaCl 0,9% or Glucose 5% 4254
Immediate precipitation Incompatible
Injection Cefotaxime sodium
Injection Pantoprazole sodium
2090
Compatible
Injection Cefotaxime sodium 100 mg/ml
Injection Paracetamol 10 mg/ml
4742
Color change after 4 hours Incompatible
Injection Cefotaxime sodium 20 mg/ml
Injection Pemetrexed disodium 20 mg/ml
Sodium chloride 0,9% 1953
Immediate precipitation Incompatible
Injection Cefotaxime sodium 20 mg/ml
Injection Pentamidine isetionate 3 mg/ml
Glucose 5% 275
Compatible
Injection Cefotaxime sodium 100 mg/ml
Injection Pentoxifyllin 5 mg/ml
NaCl 0,9% or Glucose 5% 4538
Compatible
Injection Cefotaxime sodium 300 mg/ml
Injection Pentoxifyllin 5 mg/ml
Water for Injection 4538
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Pethidine hydrochloride 10 mg/ml
Glucose 5% 405
Compatible
Injection Cefotaxime sodium 25 mg/ml
Injection Phloroglucinol 2,5 mg/ml
3791
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Propofol 10 mg/ml
None 300
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Remifentanil hydrochloride 25 & 250 µg/ml
Sodium chloride 0,9% 59
Immediate precipitation Incompatible
Injection Cefotaxime sodium 100 mg/ml
Injection Salbutamol sulfate 1 mg/ml
None 3216
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Sargramostim 10 µg/ml
Sodium chloride 0,9% 335
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Teniposide 0.1 mg/ml
Glucose 5% 905
Compatible
Injection Cefotaxime sodium 83.3 mg/ml
Injection Thiamine hydrochloride 0.4 mg/ml
Glucose 5% 4254
Precipitation after 1 hour Incompatible
Injection Cefotaxime sodium 100 mg/ml
Injection Thiopental sodium 25 mg/ml
Sodium chloride 0,9% 3767
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Thiotepa 1 mg/ml
Glucose 5% 249
Compatible
Injection Cefotaxime sodium 5 mg/ml
Injection Tinidazole 2 mg/ml
2185
Compatible
Injection Cefotaxime sodium 1 & 10 mg/ml
Injection Vancomycin hydrochloride 20 mg/ml
Glucose 5% 1674
Compatible
Injection Cefotaxime sodium 1 >> 200 mg/ml
Injection Vancomycin hydrochloride 2 mg/ml
Glucose 5% 1674
Compatible
Injection Cefotaxime sodium 100 mg/ml
Injection Vancomycin hydrochloride 5 & 12,5 mg/ml
Water for Injection 260
Immediate turbidity Incompatible
Injection Cefotaxime sodium 50 & 200 mg/ml
Injection Vancomycin hydrochloride 20 mg/ml
Glucose 5% 1674
Immediate precipitation Incompatible
Injection Cefotaxime sodium 100 mg/ml
Injection Vancomycin hydrochloride 25 & 30 mg/ml
260
Compatible
Injection Cefotaxime sodium 4 mg/ml
Injection Verapamil hydrochloride 0.08 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
Injection Cefotaxime sodium 20 mg/ml
Injection Vinorelbine tartrate 1 mg/ml
Sodium chloride 0,9% 84

  Mentions Légales