Dernière mise à jour :
18/07/2024
Bibliographie   Bibliographie 251  
Type : Revue
Lien Internet : http://www.ajhp.org/cgi/content/abstract/54/23/2708

Equipes de recherche : Houston - M.D.Anderson Cancer Center
Auteurs : Trissel LA, Gilbert DL, Martinez JF.
Titre : Compatibility of doxorubicin hydrochloride liposome injection with selected other drugs during simulated Y-site administration.
Référence : Am J Health-Syst Pharm ; 54: 2708-2713. 1997

Niveau de preuve : 
Non coté
Stabilité physique : 
Stabilité chimique : 
Autres méthodes : 
Commentaires : 
Non coté : étude de compatibilité seule

Liste des molécules
injectableAciclovir sodium Antiviral
Compatible 7 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableAllopurinol sodium Anti-goutte
Compatible 3 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableAminophylline Divers
Compatible 2.5 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableAmphotericin B Antifongique
Incompatible 0.6 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableAmpicillin sodium Antibiotique
Compatible 20 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableAztreonam Antibiotique
Compatible 40 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableBleomycin sulfate Anticancéreux
Compatible 1 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableBuprenorphine hydrochloride Antalgique
Incompatible 0.04 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableButorphanol tartrate Antalgique
Compatible 0.04 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableCalcium gluconate électrolyte
Compatible 40 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableCarboplatin Anticancéreux
Compatible 5 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableCefazolin sodium Antibiotique
Compatible 20 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableCefepime dihydrochloride Antibiotique
Compatible 20 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableCefoperazone sodium Antibiotique
Incompatible 40 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableCefoxitin sodium Antibiotique
Compatible 20 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableCeftazidime Antibiotique
Incompatible 40 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableCeftizoxime sodium Antibiotique
Compatible 20 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableCeftriaxone disodium Antibiotique
Compatible 20 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableChlorpromazine hydrochloride Anxiolytique
Compatible 2 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableCimetidine hydrochloride Antihistaminique H2
Compatible 12 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableCiprofloxacin lactate Antibiotique
Compatible 1 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableCisplatin Anticancéreux
Compatible 1 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableClindamycin phosphate Antibiotique
Compatible 10 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableCo-trimoxazole Antibiotique
Compatible 0.8/4 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableCyclophosphamide Anticancéreux
Compatible 10 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableCytarabine Anticancéreux
Compatible 50 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableDacarbazine Anticancéreux
Compatible 4 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableDiphenhydramine hydrochloride Antihistaminique H1
Compatible 2 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableDobutamine hydrochloride Cardiotonique
Compatible 4 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableDocetaxel Anticancéreux
Incompatible 2 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableDopamine hydrochloride Cardiotonique
Compatible 3.2 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableDoxorubicin hydrochloride liposome peg Anticancéreux
Facteur influençant la stabilité Solvant NaHCO3 Provoque Dégradation
Incompatible + NaHCO3
Compatible 0.4 mg/ml + injectableAciclovir sodium 7 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableAllopurinol sodium 3 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableAminophylline 2.5 mg/ml + Glucose 5%
Incompatible 0.4 mg/ml + injectableAmphotericin B 0.6 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableAmpicillin sodium 20 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableAztreonam 40 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableBleomycin sulfate 1 mg/ml + Glucose 5%
Incompatible 0.4 mg/ml + injectableBuprenorphine hydrochloride 0.04 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableButorphanol tartrate 0.04 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableCalcium gluconate 40 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableCarboplatin 5 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableCefazolin sodium 20 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableCefepime dihydrochloride 20 mg/ml + Glucose 5%
Incompatible 0.4 mg/ml + injectableCefoperazone sodium 40 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableCefoxitin sodium 20 mg/ml + Glucose 5%
Incompatible 0.4 mg/ml + injectableCeftazidime 40 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableCeftizoxime sodium 20 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableCeftriaxone disodium 20 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableChlorpromazine hydrochloride 2 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableCimetidine hydrochloride 12 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableCiprofloxacin lactate 1 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableCisplatin 1 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableClindamycin phosphate 10 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableCo-trimoxazole 0.8/4 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableCyclophosphamide 10 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableCytarabine 50 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableDacarbazine 4 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableDiphenhydramine hydrochloride 2 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableDobutamine hydrochloride 4 mg/ml + Glucose 5%
Incompatible 0.4 mg/ml + injectableDocetaxel 2 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableDopamine hydrochloride 3.2 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableDroperidol 0.4 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableEnalaprilate 0.1 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableEtoposide 0.4 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableFamotidine 2 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableFluconazole 2 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableFluorouracil 16 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableFolinate calcium 2 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableFurosemide 3 mg/ml + Glucose 5%
Incompatible 0.4 mg/ml + injectableGallium nitrate 0.4 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableGanciclovir sodium 20 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableGentamicin sulfate 5 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableGranisetron hydrochloride 0.05 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableHaloperidol lactate 0.2 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableHeparin sodium 1000 UI/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableHydrocortisone sodium succinate 1 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableHydromorphone hydrochloride 0.5 mg/ml + Glucose 5%
Incompatible 0.4 mg/ml + injectableHydroxyzine dihydrochloride 2 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableIfosfamide 25 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableLorazepam 0.1 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableMagnesium sulfate 100 mg/ml + Glucose 5%
Incompatible 0.4 mg/ml + injectableMannitol 150 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableMesna 10 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableMethotrexate sodium 15 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableMethylprednisolone sodium succinate 5 mg/ml + Glucose 5%
Incompatible 0.4 mg/ml + injectableMetoclopramide hydrochloride 5 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableMetronidazole 5 mg/ml + Glucose 5%
Incompatible 0.4 mg/ml + injectableMitoxantrone dihydrochloride 0.5 mg/ml + Glucose 5%
Incompatible 0.4 mg/ml + injectableMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableNetilmicin sulfate 5 mg/ml + Glucose 5%
Incompatible 0.4 mg/ml + injectableOfloxacin 4 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableOndansetron hydrochloride 1 mg/ml + Glucose 5%
Incompatible 0.4 mg/ml + injectablePaclitaxel 0.6 mg/ml + Glucose 5%
Incompatible 0.4 mg/ml + injectablePethidine hydrochloride 4 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectablePiperacillin sodium 40 mg/ml + Glucose 5%
Incompatible 0.4 mg/ml + injectablePiperacillin sodium / tazobactam 40/5 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectablePotassium chloride 100 mEq/l + Glucose 5%
Compatible 0.4 mg/ml + injectableProchlorperazine edysilate 0.5 mg/ml + Glucose 5%
Incompatible 0.4 mg/ml + injectablePromethazine hydrochloride 2 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableRanitidine hydrochloride 2 mg/ml + Glucose 5%
Incompatible 0.4 mg/ml + injectableSodium bicarbonate 84 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableTicarcillin / clavulanic acid 31 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableTobramycin sulfate 5 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableVancomycin hydrochloride 10 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableVinblastine sulfate 0.12 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableVincristine sulfate 0.05 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableVinorelbine tartrate 1 mg/ml + Glucose 5%
Compatible 0.4 mg/ml + injectableZidovudine 4 mg/ml + Glucose 5%
injectableDroperidol Neuroleptique
Compatible 0.4 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableEnalaprilate Antihypertenseur
Compatible 0.1 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableEtoposide Anticancéreux
Compatible 0.4 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableFamotidine Antihistaminique H2
Compatible 2 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableFluconazole Antifongique
Compatible 2 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableFluorouracil Anticancéreux
Compatible 16 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableFolinate calcium Cytoprotecteur
Compatible 2 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableFurosemide Diurétique
Compatible 3 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableGallium nitrate Hypocalcémiant
Incompatible 0.4 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableGanciclovir sodium Antiviral
Compatible 20 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableGentamicin sulfate Antibiotique
Compatible 5 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableGranisetron hydrochloride Antiémétique
Compatible 0.05 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableHaloperidol lactate Neuroleptique
Compatible 0.2 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableHeparin sodium Anticoagulant
Compatible 1000 UI/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableHydrocortisone sodium succinate Antiinflammatoire
Compatible 1 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableHydromorphone hydrochloride Antalgique
Compatible 0.5 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableHydroxyzine dihydrochloride Anxiolytique
Incompatible 2 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableIfosfamide Anticancéreux
Compatible 25 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableLorazepam Anxiolytique
Compatible 0.1 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableMagnesium sulfate électrolyte
Compatible 100 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableMannitol Divers
Incompatible 150 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableMesna Cytoprotecteur
Compatible 10 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableMethotrexate sodium Anticancéreux
Compatible 15 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableMethylprednisolone sodium succinate Antiinflammatoire
Compatible 5 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableMetoclopramide hydrochloride Antiémétique
Incompatible 5 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableMetronidazole Antiparasitaire
Compatible 5 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableMitoxantrone dihydrochloride Anticancéreux
Incompatible 0.5 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableMorphine sulfate Antalgique
Incompatible 1 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableNetilmicin sulfate Antibiotique
Compatible 5 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableOfloxacin Antibiotique
Incompatible 4 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableOndansetron hydrochloride Antiémétique
Compatible 1 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectablePaclitaxel Anticancéreux
Incompatible 0.6 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectablePethidine hydrochloride Antalgique
Incompatible 4 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectablePiperacillin sodium Antibiotique
Compatible 40 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectablePiperacillin sodium / tazobactam Antibiotique
Incompatible 40/5 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectablePotassium chloride électrolyte
Compatible 100 mEq/l + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableProchlorperazine edysilate Neuroleptique
Compatible 0.5 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectablePromethazine hydrochloride Antihistaminique H1
Incompatible 2 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableRanitidine hydrochloride Antihistaminique H2
Compatible 2 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableSodium bicarbonate électrolyte
Incompatible 84 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableTicarcillin / clavulanic acid Antibiotique
Compatible 31 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableTobramycin sulfate Antibiotique
Compatible 5 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableVancomycin hydrochloride Antibiotique
Compatible 10 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableVinblastine sulfate Anticancéreux
Compatible 0.12 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableVincristine sulfate Anticancéreux
Compatible 0.05 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableVinorelbine tartrate Anticancéreux
Compatible 1 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%
injectableZidovudine Antiviral
Compatible 4 mg/ml + injectableDoxorubicin hydrochloride liposome peg 0.4 mg/ml + Glucose 5%

  Mentions Légales