Last update :
16/06/2024
Antihistamine (H2)   Cimetidine hydrochloride  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Acidnor Egypt
Acinil Denmark, Sweden
Antagon Morocco
Cimehexal Germany, Luxembourg
Cimetag United Arab Emirates
Cimetidin Germany
Cimetidina Chile, Venezuela
Cimetidine Iran, Netherlands, Poland, United States of America
Cimulcer Malaysia
Columina Mexico
Lenamet Republic of South Africa
Mexine Tunisia
Neutronorm Austria
Tagamet Australia, Germany, Greece, Ireland, Italy, United Arab Emirates
Ulcometin Austria
Ulcostab Austria
Compatibility   Injection   Compatibility : Cimetidine hydrochloride              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Acetazolamide 5 mg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Anidulafungin 0.5 mg/ml
Glucose 5% 1982
Compatible
Injection Cimetidine hydrochloride 0.4 >> 1.2 mg/ml
Parenteral nutrition (with lipids) 362
Compatible
Injection Cimetidine hydrochloride 6 mg/ml
Injection Aciclovir sodium 5 mg/ml
Glucose 5% 336
Precipitation after 1 hour Incompatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Allopurinol sodium 3 mg/ml
Sodium chloride 0,9% 307
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Amifostine 10 mg/ml
Glucose 5% 3
Compatible
Injection Cimetidine hydrochloride 1.5 mg/ml
Injection Amikacin sulfate 2.5 mg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 1,2 mg/ml
Injection Aminophylline 0,5 mg/ml
Glucose 5% 539
Immediate turbidity Incompatible
Injection Cimetidine hydrochloride 0.6 mg/ml
Injection Amphotericin B 0.1 mg/ml
Glucose 5% 1201
Immediate precipitation Incompatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Amphotericin B cholesteryl sulfate complex 0.83 mg/ml
Glucose 5% 921
Compatible
Injection Cimetidine hydrochloride 1.2 & 5 mg/ml
Injection Ampicillin sodium 1 mg/ml
NaCl 0,9% or Glucose 5% 1201
Precipitation after 1 hour Incompatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Amsacrine 1 mg/ml
Glucose 5% 253
Compatible
Injection Cimetidine hydrochloride 6 mg/ml
Injection Atracurium besylate 0.5 mg/ml
Glucose 5% 402
Compatible
Injection Cimetidine hydrochloride 85.7 & 100 mg/ml
Injection Atropine sulfate 0.13 & 0.17 mg/ml
None 1203
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Aztreonam 40 mg/ml
Glucose 5% 99
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Parenteral nutrition (with lipids) 1415
Precipitation after 24 hours Incompatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Cefalotin sodium 10 mg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 10 mg/ml
Parenteral nutrition (binary mixture) 939
Immediate turbidity Incompatible
Injection Cimetidine hydrochloride 6 mg/ml
Injection Cefamandole nafate 20 mg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 0.3 mg/ml
Injection Cefamandole nafate 1 mg/ml
Glucose 5% 1201
Turbidity in 24 hours Incompatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Cefazolin sodium 10 mg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 1.2 mg/ml
Injection Ciprofloxacin lactate 2 mg/ml
Glucose 5% 285
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Cisatracurium besylate 0.1 >> 5 mg/ml
Glucose 5% 299
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Parenteral nutrition (binary mixture) 301
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Bivalirudin 5 mg/ml
Glucose 5% 1713
Compatible
Injection Cimetidine hydrochloride 1.2 mg/ml
Injection Cefalotin sodium 3 mg/ml
NaCl 0,9% or Glucose 5% 1201
Precipitation after 24 hours Incompatible
Injection Cimetidine hydrochloride 5 mg/ml
Injection Cefalotin sodium 3 mg/ml
NaCl 0,9% or Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 1.2 & 5 mg/ml
Injection Cefazolin sodium 1 mg/ml
NaCl 0,9% or Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 2 mg/ml
Injection Cefoperazone sodium 5 mg/ml
Glucose 5% 79
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Cefoxitin sodium 10 mg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Chlorothiazide sodium 5 mg/ml
Glucose 5% 1201
Immediate turbidity Incompatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Chlorpromazine hydrochloride 25 mg/ml
1438
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Cladribine 0.5 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Cladribine 0.015 mg/ml
Sodium chloride 0,9% 1496
Compatible
Injection Cimetidine hydrochloride 1.2 & 5 mg/ml
Injection Clindamycin phosphate 1.2 mg/ml
NaCl 0,9% or Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Colistin mesilate sodium 1.5 mg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Dexamethasone sodium phosphate 0.04 mg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Dexmedetomidine 4 µg/ml
Sodium chloride 0,9% 1712
Compatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Diatrizoate meglumine 283 mg/ml
None 1085
Compatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Diazepam 5 mg/ml
1438
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Digoxin 2.5 µg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Diltiazem hydrochloride 1 & 5 mg/ml
Sodium chloride 0,9% 198
Compatible
Injection Cimetidine hydrochloride 6 mg/ml
Injection Diltiazem hydrochloride 5 mg/ml
Sodium chloride 0,9% 198
Compatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Diphenhydramine hydrochloride 50 mg/ml
1438
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Docetaxel 0.9 mg/ml
Glucose 5% 1754
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Doripenem 5 mg/ml
NaCl 0,9% or Glucose 5% 2262
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Doxorubicin hydrochloride liposome peg 0.4 mg/ml
Glucose 5% 251
Compatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Droperidol 2,5 mg/ml
1438
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Enalaprilate 0.05 mg/ml
Sodium chloride 0,9% 1315
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Epinephrine hydrochloride 0.1 µg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Erythromycin lactobionate 5 mg/ml
Sodium chloride 0,9% 1201
Compatible
Injection Cimetidine hydrochloride 6 mg/ml
Injection Esmolol hydrochloride 10 mg/ml
Glucose 5% 384
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Ethacrynate sodium 0.5 mg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Etoposide phosphate 5 mg/ml
Glucose 5% 1410
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Compatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Fentanyl citrate 50 µg/ml
1438
Compatible
Injection Cimetidine hydrochloride 15 mg/ml
Injection Fentanyl citrate 50 µg/ml
Glucose 5% 63
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Filgrastim 30 µg/ml
Glucose 5% 244
Compatible
Injection Cimetidine hydrochloride 4 mg/ml
Injection Flucloxacillin sodium 20 mg/ml
Sodium chloride 0,9% 1232
Compatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Fluconazole 2 mg/ml
Sodium chloride 0,9% 496
Compatible
Injection Cimetidine hydrochloride 1 & 2 mg/ml
Injection Fluconazole 2 mg/ml
NaCl 0,9% or Glucose 5% 255
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Fludarabine phosphate 1 mg/ml
Glucose 5% 492
Compatible
Injection Cimetidine hydrochloride 2,4 mg/ml
Injection Flumazenil 0,02 mg/ml
Glucose 5% 187
Compatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Foscarnet sodium 24 mg/ml
None 73
Compatible
Injection Cimetidine hydrochloride 4 mg/ml
Injection Furosemide 1 mg/ml
Sodium chloride 0,9% 1232
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Furosemide 0.4 mg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 15 mg/ml
Injection Gallium nitrate 1 mg/ml
Sodium chloride 0,9% 91
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Gemcitabine hydrochloride 10 mg/ml
Sodium chloride 0,9% 1423
Compatible
Injection Cimetidine hydrochloride 1.2 & 5 mg/ml
Injection Gentamicin sulfate 0.08 mg/ml
NaCl 0,9% or Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Gentamicin sulfate 0.8 mg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Glycopyrronium bromide 0.2 mg/ml
1438
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Granisetron hydrochloride 1 mg/ml
Sodium chloride 0,9% 57
Compatible
Injection Cimetidine hydrochloride 6 mg/ml
Injection Haloperidol lactate 0.5 & 5 mg/ml
Glucose 5% 403
Compatible
Injection Cimetidine hydrochloride 6 mg/ml
Injection Heparin sodium 50 UI/ml
None 317
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Hetastarch 60 mg/ml
Specific solvent 1721
Compatible
Injection Cimetidine hydrochloride 6 mg/ml
Injection Hetastarch 60 mg/ml
Sodium chloride 0,9% 465
Compatible
Injection Cimetidine hydrochloride 6 mg/ml
Injection Hetastarch 60 mg/ml
Sodium chloride 0,9% 472
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Hydrocortisone sodium succinate 0.4 & 1.25 mg/ml
Glucose 5% 211
Compatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Hydromorphone hydrochloride 2 mg/ml
1438
Compatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Hydroxyzine dihydrochloride 50 mg/ml
1438
Compatible
Injection Cimetidine hydrochloride 6 mg/ml
Injection Idarubicin hydrochloride 1 mg/ml
Sodium chloride 0,9% 491
Compatible
Injection Cimetidine hydrochloride 1.2 & 5 mg/ml
Injection Insulin 0.1 UI/ml
NaCl 0,9% or Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Iohexol 300 mg I/ml
None 1085
Immediate precipitation Incompatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Ioxaglate 320 mg I/ml
None 1085
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Isoprenaline hydrochloride 0.02 mg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Labetalol hydrochloride 1 mg/ml
Glucose 5% 386
Immediate precipitation Incompatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Lansoprazole 0.55 mg/ml
Sodium chloride 0,9% 1625
Compatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Levofloxacine 5 mg/ml
Glucose 5% 1072
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Lidocaine hydrochloride 1.25 mg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Lincomycin 6 mg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Linezolid 2 mg/ml
None 1925
Compatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Lorazepam 2 mg/ml
1438
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Melphalan 0.1 mg/ml
Sodium chloride 0,9% 169
Compatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Meropenem 1 & 50 mg/ml
Sodium chloride 0,9% 266
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Meropenem 1 & 20 mg/ml
Sodium chloride 0,9% 266
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Metaraminol 1 mg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Methylprednisolone sodium succinate 0.4 mg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 15 mg/ml
Injection Midazolam hydrochloride 1 mg/ml
Glucose 5% 176
Compatible
Injection Cimetidine hydrochloride 0.8 mg/ml
Injection Midazolam hydrochloride 0.05 & 0.25 mg/ml
Sodium chloride 0,9% 1888
Compatible
Injection Cimetidine hydrochloride 100 mg/ml
Injection Midazolam hydrochloride 1.67 mg/ml
None 404
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Milrinone lactate 0.8 mg/ml
Glucose 5% 813
Compatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Morphine sulfate 10 mg/ml
1438
Compatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Nalbuphine hydrochloride 10 mg/ml
1438
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Nicardipine hydrochloride 0.1 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Nitroprusside sodium 0.5 mg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Norepinephrine bitartrate 0.04 mg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Ondansetron hydrochloride 1 mg/ml
Sodium chloride 0,9% 334
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Oritavancin 0.8 >>2 mg/ml
Glucose 5% 3152
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Oxaliplatin 0,5 mg/ml
Glucose 5% 1662
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Paclitaxel 1.2 mg/ml
Glucose 5% 85
Compatible
Injection Cimetidine hydrochloride 6 mg/ml
Injection Pancuronium bromide 0.05 mg/ml
Glucose 5% 402
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Pemetrexed disodium 20 mg/ml
Sodium chloride 0,9% 1953
Compatible
Injection Cimetidine hydrochloride 1.2 & 5 mg/ml
Injection Penicillin G potassium 0.0024 MUI/ml
NaCl 0,9% or Glucose 5% 1201
Unspecified incompatibility Incompatible
Injection Cimetidine hydrochloride
Injection Penicillin G sodium
3585
Unspecified incompatibility Incompatible
Injection Cimetidine hydrochloride
Injection Pentobarbital sodium
3592
Immediate precipitation Incompatible
Injection Cimetidine hydrochloride 75 mg/ml
Injection Pentobarbital sodium 25 mg/ml
None 1203
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Phytomenadione 0.1 mg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Piperacillin sodium / tazobactam 40/5 mg/ml
Glucose 5% 81
Compatible
Injection Cimetidine hydrochloride 1.2 mg/ml
Injection Potassium chloride 20 & 80 mEq/l
NaCl 0,9% or Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Prochlorperazine edysilate 5 mg/ml
1438
Compatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Promethazine hydrochloride 25 mg/ml
1438
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Propofol 10 mg/ml
None 300
Instability of the emulsion after 4 hours Incompatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Propofol
660
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Protamine hydrochloride 0.5 UI/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Quinidine gluconate 3.2 mg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Remifentanil hydrochloride 25 & 250 µg/ml
Sodium chloride 0,9% 59
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Sargramostim 10 µg/ml
Sodium chloride 0,9% 335
Compatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Scopolamine hydrobromide 0,86 mg/ml
1438
Compatible
Injection Cimetidine hydrochloride 150 mg/ml
Injection Tacrolimus 1000 µg/ml
Sodium chloride 0,9% 479
Compatible
Injection Cimetidine hydrochloride 0,6 mg/ml
Injection Tacrolimus 10 µg/ml
Sodium chloride 0,9% 207
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Teniposide 0.1 mg/ml
Glucose 5% 905
Compatible
Injection Cimetidine hydrochloride 6 mg/ml
Injection Theophylline 4 mg/ml
None 317
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Thiotepa 1 mg/ml
Glucose 5% 249
Compatible
Injection Cimetidine hydrochloride 5.76 mg/ml
Injection Topotecan 0.056 mg/ml
NaCl 0,9% or Glucose 5% 1026
Compatible
Injection Cimetidine hydrochloride 3 mg/ml
Injection Vancomycin hydrochloride 5 mg/ml
Glucose 5% 1201
Compatible
Injection Cimetidine hydrochloride 6 mg/ml
Injection Vecuronium bromide 0.1 mg/ml
Glucose 5% 402
Compatible
Injection Cimetidine hydrochloride 12 mg/ml
Injection Vinorelbine tartrate 1 mg/ml
Sodium chloride 0,9% 84
Turbidity in one hour Incompatible
Injection Cimetidine hydrochloride 3,6 mg/ml
Injection Warfarin sodium 2 mg/ml
Glucose 5% 315
Compatible
Injection Cimetidine hydrochloride 6 mg/ml
Injection Zidovudine 4 mg/ml
Glucose 5% 337

  Mentions Légales