Last update :
18/07/2024
Various   Mannitol  
injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Deltamannit Germany
Demanitol Peru
Ecobrain Peru
Gravert India
Isotol Italy
Manitol Ecuador, Mexico, Peru, Romania, Venezuela
Mannit Austria, Germany
Mannitol Canada, Denmark, Egypt, Finland, France, Germany, Great Britain, Greece, Hungary, Iceland, Ireland, Luxembourg, Norway, Poland, Saudi Arabia, Sweden, Switzerland, Tunisia, Turkey, United Arab Emirates, United States of America
Osmitrol Australia, Canada, Saudi Arabia, United States of America
Osmofundin Austria, Luxembourg
Osmorin Ecuador
Osmosteril Austria, Germany, Luxembourg
Staloral Saudi Arabia
Compatibility   injection   Compatibility : Mannitol              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
injection Mannitol 150 mg/ml
injection Allopurinol sodium 3 mg/ml
Sodium chloride 0,9% 307
Compatible
injection Mannitol 150 mg/ml
injection Amifostine 10 mg/ml
Glucose 5% 3
Unspecified incompatibility Incompatible
injection Mannitol
injection Amoxicillin sodium / clavulanic acid
3545
Compatible
injection Mannitol 250 mg/ml
injection Amoxicillin sodium / clavulanic acid 100/10 mg/ml
3824
Compatible
injection Mannitol 150 mg/ml
injection Amphotericin B cholesteryl sulfate complex 0.83 mg/ml
Glucose 5% 921
Compatible
injection Mannitol 0.15 mg/ml
injection Aztreonam 40 mg/ml
Glucose 5% 99
Compatible
injection Mannitol 150 mg/ml
injection Bivalirudin 5 mg/ml
Glucose 5% 1713
Compatible
injection Mannitol 250 mg/ml
injection Caffeine 10 mg/ml
None 3964
Unspecified incompatibility Incompatible
injection Mannitol 100 & 200 mg/ml
injection Cefamandole nafate
1165
Compatible
injection Mannitol 200 mg/ml
injection Cefiderocol sulfate tosylate 20 mg/mL
NaCl 0,9% or Glucose 5% 4528
Compatible
injection Mannitol 150 mg/ml
injection Ceftaroline fosamil 2,22 mg/ml
Ringer’s lactate solution 3249
Compatible
injection Mannitol 150 mg/ml
injection Ceftaroline fosamil 2,22 mg/ml
NaCl 0,9% or Glucose 5% 3249
Compatible
injection Mannitol 150 mg/ml
injection Ceftobiprole medocaril sodium 2 mg/ml
NaCl 0,9% or Glucose 5% 2269
Compatible
injection Mannitol 150 mg/ml
injection Ceftobiprole medocaril sodium 2 mg/ml
Ringer’s lactate solution 2269
Compatible
injection Mannitol 250 mg/ml
injection Ceftolozane / tazobactam 10/5 mg/ml
NaCl 0,9% or Glucose 5% 3828
Compatible
injection Mannitol 150 mg/ml
injection Cisatracurium besylate 0.1 >> 5 mg/ml
Glucose 5% 299
Compatible
injection Mannitol 150 mg/ml
injection Cladribine 0.015 mg/ml
Sodium chloride 0,9% 1496
Compatible
injection Mannitol 150 mg/ml
injection Cladribine 0.5 mg/ml
NaCl 0,9% + antibacterial 1496
Compatible
injection Mannitol 250 mg/ml
injection Cloxacillin sodium 100 mg/ml
Water for Injection 3012
Compatible
injection Mannitol 20 mg/ml
injection Dopamine hydrochloride 0.8 mg/ml
732
Compatible
injection Mannitol 200 mg/ml
injection Fluorouracil 1 & 2 mg/ml
Sodium chloride 0,9% 411
Compatible
injection Mannitol 200 mg/ml
injection Fosfomycin 30 mg/ml
NaCl 0,9% or Glucose 5% 4055
Compatible
injection Mannitol 250 mg/ml
injection Gallium nitrate 1 mg/ml
Sodium chloride 0,9% 91
Compatible
injection Mannitol 250 mg/ml
Ringer’s lactate solution 4603
Loss of turbidity Incompatible
injection Mannitol 150 mg/ml
injection Doxorubicin hydrochloride liposome peg 0.4 mg/ml
Glucose 5% 251
Compatible
injection Mannitol 150 mg/ml
injection Etoposide phosphate 5 mg/ml
Glucose 5% 1410
Compatible
injection Mannitol 150 mg/ml
injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Compatible
injection Mannitol 150 mg/ml
injection Fludarabine phosphate 1 mg/ml
Glucose 5% 492
Compatible
injection Mannitol 150 mg/ml
Parenteral nutrition (with lipids) 1415
Compatible
injection Mannitol 150 mg/ml
injection Doripenem 5 mg/ml
NaCl 0,9% or Glucose 5% 2262
Chemical instability Incompatible
injection Mannitol 100 & 200 mg/ml
injection Ertapenem 10 & 20 mg/ml
None 1906
Compatible
injection Mannitol 200 mg/ml
injection Furosemide 10 mg/ml
Sodium chloride 0,9% 3823
Compatible
injection Mannitol 150 mg/ml
injection Gemcitabine hydrochloride 10 mg/ml
Sodium chloride 0,9% 1423
Compatible
injection Mannitol 150 mg/ml
Parenteral nutrition (binary mixture) 301
Immediate precipitation Incompatible
injection Mannitol 150 mg/ml
injection Filgrastim 30 µg/ml
Glucose 5% 244
Compatible
injection Mannitol 150 mg/ml
injection Hetastarch 60 mg/ml
specific solvent 1721
Compatible
injection Mannitol 12.5 mg/ml
injection Idarubicin hydrochloride 1 mg/ml
Sodium chloride 0,9% 491
Compatible
injection Mannitol 200 mg/ml
injection Isavuconazonium sulfate 1.5 mg/ml
NaCl 0,9% or Glucose 5% 3829
Compatible
injection Mannitol 150 mg/ml
injection Lansoprazole 0.55 mg/ml
Sodium chloride 0,9% 1625
Compatible
injection Mannitol 150 mg/ml
injection Linezolid 2 mg/ml
None 1925
Compatible
injection Mannitol 150 mg/ml
injection Melphalan 0.1 mg/ml
Sodium chloride 0,9% 169
Compatible
injection Mannitol 250 mg/ml
injection Meropenem 50 mg/ml
Water for Injection 4319
Compatible
injection Mannitol 250 mg/ml
injection N-acetylcysteine 200 mg/ml
None 3766
Compatible
injection Mannitol 250 mg/ml
injection Naloxone hydrochloride 0.4 mg/ml
None 3408
Compatible
injection Mannitol 150 mg/ml
injection Ondansetron hydrochloride 1 mg/ml
Sodium chloride 0,9% 334
Compatible
injection Mannitol 150 mg/ml
injection Oxaliplatin 0,5 mg/ml
Glucose 5% 1662
Compatible
injection Mannitol 150 mg/ml
injection Paclitaxel 1.2 mg/ml
Glucose 5% 248
Compatible
injection Mannitol 150 mg/ml
injection Palonosetron hydrochloride 50 µg/ml
None 2281
Immediate precipitation Incompatible
injection Mannitol
injection Pantoprazole sodium
2090
Compatible
injection Mannitol 250 mg/ml
injection Paracetamol 10 mg/ml
4742
Compatible
injection Mannitol 150 mg/ml
injection Pemetrexed disodium 20 mg/ml
Sodium chloride 0,9% 1953
Compatible
injection Mannitol 200 mg/ml
injection Phenytoin sodium 5 mg/ml
Sodium chloride 0,9% 3315
Compatible
injection Mannitol 150 mg/ml
injection Piperacillin sodium / tazobactam 40/5 mg/ml
Glucose 5% 81
Compatible
injection Mannitol 200 mg/ml
injection Plazomicin sulfate 24 mg/ml
Sodium chloride 0,9% 4145
Compatible
injection Mannitol 20 mg/ml
injection Potassium chloride 10000 & 40000 mEq/l
Sodium chloride 0,9% 1906
Compatible
injection Mannitol 150 mg/ml
injection Propofol 10 mg/ml
None 300
Compatible
injection Mannitol 150 mg/ml
injection Remifentanil hydrochloride 25 & 250 µg/ml
Sodium chloride 0,9% 59
Compatible
injection Mannitol 150 mg/ml
injection Sargramostim 10 µg/ml
Sodium chloride 0,9% 335
Compatible
injection Mannitol 25 mg/ml
injection Sodium bicarbonate 3.75 mg/ml
Glucose 5% 322
Compatible
injection Mannitol 25 mg/ml
injection Sodium bicarbonate 37,39 mg/ml
NaCl 0,45% Glucose 5% 298
Compatible
injection Mannitol 25 mg/ml
injection Sodium bicarbonate 3.75 mg/ml
Ringer’s lactate solution 322
Compatible
injection Mannitol 25 mg/ml
injection Sodium bicarbonate 3.75 mg/ml
Glucose 10% 322
Compatible
injection Mannitol 25 mg/ml
injection Sodium bicarbonate 3.75 mg/ml
Sodium chloride 0,45% 322
Compatible
injection Mannitol 25 mg/ml
injection Sodium bicarbonate 37,39 mg/ml
NaCl 0,9% or Glucose 5% 298
Compatible
injection Mannitol 200 mg/ml
injection Tedizolid phosphate 0.8 mg/ml
Sodium chloride 0,9% 3827
Compatible
injection Mannitol 200 mg/ml
injection Telavancin hydrochloride 7.5 mg/ml
NaCl 0,9% or Glucose 5% 3254
Compatible
injection Mannitol 200 mg/ml
injection Telavancin hydrochloride 7.5 mg/ml
Ringer’s lactate solution 3254
Compatible
injection Mannitol 150 mg/ml
injection Teniposide 0.1 mg/ml
Glucose 5% 905
Unspecified incompatibility Incompatible
injection Mannitol 200 mg/ml
injection Thiopental sodium 60 mg/ml
Sodium chloride 0,9% 3823
Compatible
injection Mannitol 150 mg/ml
injection Thiotepa 1 mg/ml
Glucose 5% 249
Compatible
injection Mannitol 20 mg/ml
injection Tramadol hydrochloride 0,4 mg/ml
None 2002
Compatible
injection Mannitol 150 mg/ml
injection Valproic acid 2 & 20 mg/ml
NaCl 0,9% or Glucose 5% 4428
Compatible
injection Mannitol 200 mg/ml
injection Valproic acid 16 mg/ml
Sodium chloride 0,9% 3823
Compatible
injection Mannitol 0.025 mg/ml
injection Verapamil hydrochloride 0.08 mg/ml
NaCl 0,9% or Glucose 5% 1057
Compatible
injection Mannitol 150 mg/ml
injection Vinorelbine tartrate 1 mg/ml
Sodium chloride 0,9% 84

  Mentions Légales