Last update :
30/09/2020
References   References 4434  
Type : Journal
Web link : https://doi.org/10.1016/j.clinthera.2019.08.005

Research teams : Hartford - Center for Anti-Infective Research and Development
Authors : Avery L.M, Chen, I.H, Reyes, S, Nicolau, D.P, Kuti J.L.
Title : Assessment of the Physical Compatibility of Eravacycline and Common Parenteral Drugs During Simulated Y-site Administration.
Reference : Clin Ther ; 41, 10: 2162-2170. 2019

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
InjectionAmiodarone hydrochloride Anti-arrhythmic
Incompatible 2 mg/ml + InjectionEravacycline 0,6 mg/ml + Sodium chloride 0,9%
InjectionCeftaroline fosamil Antibiotic
Incompatible 12 mg/ml + InjectionEravacycline 0,6 mg/ml + Sodium chloride 0,9%
InjectionColistin mesilate sodium Antibiotic
Incompatible 4,5 mg/ml + InjectionEravacycline 0,6 mg/ml + Sodium chloride 0,9%
InjectionEravacycline Antibiotic
Incompatible 0,6 mg/ml + InjectionAmiodarone hydrochloride 2 mg/ml + Sodium chloride 0,9%
Incompatible 0,6 mg/ml + InjectionCeftaroline fosamil 12 mg/ml + Sodium chloride 0,9%
Incompatible 0,6 mg/ml + InjectionColistin mesilate sodium 4,5 mg/ml + Sodium chloride 0,9%
Incompatible 0,6 mg/ml + InjectionFurosemide 3 mg/ml + Sodium chloride 0,9%
Incompatible 0,6 mg/ml + InjectionHuman albumin 250 mg/ml + Sodium chloride 0,9%
Incompatible 0,6 mg/ml + InjectionMeropenem 20 mg/ml + Sodium chloride 0,9%
Incompatible 0,6 mg/ml + InjectionMeropenem Vaborbactam 8/8 mg/ml + Sodium chloride 0,9%
Incompatible 0,6 mg/ml + InjectionMicafungin 4 mg/ml + Sodium chloride 0,9%
Incompatible 0,6 mg/ml + InjectionPropofol 10 mg/ml + Sodium chloride 0,9%
Incompatible 0,6 mg/ml + InjectionSodium bicarbonate 84 mg/ml + Sodium chloride 0,9%
Incompatible 0,6 mg/ml + Glucose 5%
InjectionFurosemide Diuretic
Incompatible 3 mg/ml + InjectionEravacycline 0,6 mg/ml + Sodium chloride 0,9%
InjectionHuman albumin Various
Incompatible 250 mg/ml + InjectionEravacycline 0,6 mg/ml + Sodium chloride 0,9%
InjectionMeropenem Antibiotic
Incompatible 20 mg/ml + InjectionEravacycline 0,6 mg/ml + Sodium chloride 0,9%
InjectionMeropenem Vaborbactam Antibiotic
Incompatible 8/8 mg/ml + InjectionEravacycline 0,6 mg/ml + Sodium chloride 0,9%
InjectionMicafungin Antifungal
Incompatible 4 mg/ml + InjectionEravacycline 0,6 mg/ml + Sodium chloride 0,9%
InjectionPropofol General anesthetic
Incompatible 10 mg/ml + InjectionEravacycline 0,6 mg/ml + Sodium chloride 0,9%
InjectionSodium bicarbonate Electrolyte
Incompatible 84 mg/ml + InjectionEravacycline 0,6 mg/ml + Sodium chloride 0,9%

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