Last update :
10/07/2024
References   References 2231  
Type : Journal
Web link : https://doi.org/10.1093/jac/dkm467

Research teams : Louvain - Drug Research Institute, University of Louvain
Authors : de Jongh R, Hens R, Basma V, mouton JW, Tulkens PM, Carryn S.
Title : Continuous versus intermittent infusion of temocillin, a directed spectrum penicillin for intensive care patients with nosocomial pneumonia: stability, compatibility, population pharmacokinetic studies and breakpoint selection.
Reference : J Antimicrob Chemother ; 61, 2: 382-388. 2008

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAmikacin sulfate Antibiotic
Compatible 15 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionAmoxicillin sodium / clavulanic acid Antibiotic
Incompatible 20 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionCefepime dihydrochloride Antibiotic
Incompatible 200 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionCeftazidime Antibiotic
Incompatible 20 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionCefuroxime sodium Antibiotic
Compatible 30 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionCiprofloxacin lactate Antibiotic
Incompatible 2 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionClindamycin phosphate Antibiotic
Incompatible 12 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionDobutamine hydrochloride Cardiotonic
Compatible 1 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionDopamine hydrochloride Cardiotonic
Compatible 0.4 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionEnoxaparin sodium Anticoagulant
Compatible 100 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionEpinephrine hydrochloride Sympathomimetic
Compatible 50 µg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionErythromycin lactobionate Antibiotic
Compatible 5 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionFlucloxacillin sodium Antibiotic
Compatible 250 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionFluconazole Antifungal
Compatible 2 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionFurosemide Diuretic
Compatible 10 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionGentamicin sulfate Antibiotic
Compatible 6 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionInsulin Glucose-lowering
Compatible 100 UI/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionIsosorbide dinitrate Vasodilator
Compatible 0.2 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionKetamine hydrochloride General anesthetic
Compatible 10 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionMeropenem Antibiotic
Incompatible 50 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionMidazolam hydrochloride Anxiolytic
Incompatible 5 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionMilrinone lactate Cardiotonic
Incompatible 0.2 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionMoxifloxacin Antibiotic
Compatible 1.6 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionN-acetylcysteine Antidote
Compatible 100 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionNicardipine hydrochloride Vasodilator
Incompatible 1 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionNimodipine Antihypertensive
Compatible 0.2 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionOmeprazole sodium Proton pump inhibitor
Compatible 0.4 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionParacetamol Analgesic
Compatible 10 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionPhenytoin sodium Antiepileptic
Compatible 50 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionPhytomenadione Vitamin
Incompatible 0.1 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionPiperacillin sodium / tazobactam Antibiotic
Incompatible 200 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionPiritramide Analgesic
Incompatible 2 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionPropofol General anesthetic
Incompatible 1 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionRanitidine hydrochloride Antihistamine (H2)
Incompatible 2.5 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionSufentanil citrate Analgesic
Compatible 0.005 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionTemocilline Antibiotic
Compatible 83.33 mg/ml + injectionAmikacin sulfate 15 mg/ml + Water for Injection
Incompatible 83.33 mg/ml + injectionAmoxicillin sodium / clavulanic acid 20 mg/ml + Water for Injection
Incompatible 83.33 mg/ml + injectionCefepime dihydrochloride 200 mg/ml + Water for Injection
Incompatible 83.33 mg/ml + injectionCeftazidime 20 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionCefuroxime sodium 30 mg/ml + Water for Injection
Incompatible 83.33 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + Water for Injection
Incompatible 83.33 mg/ml + injectionClindamycin phosphate 12 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionDobutamine hydrochloride 1 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionDopamine hydrochloride 0.4 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionEnoxaparin sodium 100 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionEpinephrine hydrochloride 50 µg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionErythromycin lactobionate 5 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionFlucloxacillin sodium 250 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionFluconazole 2 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionFurosemide 10 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionGentamicin sulfate 6 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionInsulin 100 UI/ml + Water for Injection
Compatible 83.33 mg/ml + injectionIsosorbide dinitrate 0.2 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionKetamine hydrochloride 10 mg/ml + Water for Injection
Incompatible 83.33 mg/ml + injectionMeropenem 50 mg/ml + Water for Injection
Incompatible 83.33 mg/ml + injectionMidazolam hydrochloride 5 mg/ml + Water for Injection
Incompatible 83.33 mg/ml + injectionMilrinone lactate 0.2 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionMoxifloxacin 1.6 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionN-acetylcysteine 100 mg/ml + Water for Injection
Incompatible 83.33 mg/ml + injectionNicardipine hydrochloride 1 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionNimodipine 0.2 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionOmeprazole sodium 0.4 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionParacetamol 10 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionPhenytoin sodium 50 mg/ml + Water for Injection
Incompatible 83.33 mg/ml + injectionPhytomenadione 0.1 mg/ml + Water for Injection
Incompatible 83.33 mg/ml + injectionPiperacillin sodium / tazobactam 200 mg/ml + Water for Injection
Incompatible 83.33 mg/ml + injectionPiritramide 2 mg/ml + Water for Injection
Incompatible 83.33 mg/ml + injectionPropofol 1 mg/ml + Water for Injection
Incompatible 83.33 mg/ml + injectionRanitidine hydrochloride 2.5 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionSufentanil citrate 0.005 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionTheophylline 200 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionThiopental sodium 0.005 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionTobramycin sulfate 6 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionTramadol hydrochloride 50 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionUrapidil 5 mg/ml + Water for Injection
Compatible 83.33 mg/ml + injectionValproic acid 100 mg/ml + Water for Injection
Incompatible 83.33 mg/ml + injectionVancomycin hydrochloride 30 mg/ml + Water for Injection
injectionTheophylline Various
Compatible 200 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionThiopental sodium General anesthetic
Compatible 0.005 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionTobramycin sulfate Antibiotic
Compatible 6 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionTramadol hydrochloride Analgesic
Compatible 50 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionUrapidil Antihypertensive
Compatible 5 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionValproic acid Antiepileptic
Compatible 100 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection
injectionVancomycin hydrochloride Antibiotic
Incompatible 30 mg/ml + injectionTemocilline 83.33 mg/ml + Water for Injection

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