Last update :
10/07/2024
References   References 1982  
Type : Journal

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Trissel LA, Ogundele AB.
Title : Compatibility of anidulafungin with other drugs during simulated Y-site administration.
Reference : Am J Health-Syst Pharm ; 62: 834-837. 2005

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAciclovir sodium Antiviral
Compatible 7 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionAmikacin sulfate Antibiotic
Compatible 5 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionAminophylline Various
Compatible 2.5 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionAmphotericin B Antifungal
Incompatible 0,6 mg/ml + injectionAnidulafungin 0,5 mg/ml + Glucose 5%
injectionAmphotericin B cholesteryl sulfate complex Antifungal
Compatible 1 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionAmphotericin B liposomale Antifungal
Compatible 1 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionAmpicillin sodium Antibiotic
Compatible 20 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionAmpicillin sodium - sulbactam sodium Antibiotic
Compatible 20/10 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionAnidulafungin Antifungal
Factors which affect stability Solvent NaHCO3 Induces Degradation
Compatible 0.5 mg/ml + injectionAciclovir sodium 7 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionAmikacin sulfate 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionAminophylline 2.5 mg/ml + Glucose 5%
Incompatible 0,5 mg/ml + injectionAmphotericin B 0,6 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionAmphotericin B cholesteryl sulfate complex 1 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionAmphotericin B liposomale 1 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionAmpicillin sodium 20 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionAmpicillin sodium - sulbactam sodium 20/10 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionCarboplatin 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionCefazolin sodium 20 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionCefepime dihydrochloride 20 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionCefoxitin sodium 20 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionCeftazidime 40 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionCeftizoxime sodium 20 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionCeftriaxone disodium 20 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionCefuroxime sodium 30 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionCiclosporin 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionCimetidine hydrochloride 12 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionCisplatin 1 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionClindamycin phosphate 10 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionCo-trimoxazole 4/0.8 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionCyclophosphamide 10 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionCytarabine 50 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionDaunorubicin hydrochloride 1 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionDexamethasone sodium phosphate 1 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionDigoxin 250 µg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionDobutamine hydrochloride 4 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionDocetaxel 2 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionDopamine hydrochloride 3.2 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionDoxorubicin hydrochloride 2 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionEpinephrine hydrochloride 50 µg/ml + Glucose 5%
Incompatible 0.5 mg/ml + injectionErtapenem 20 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionErythromycin lactobionate 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionEtoposide phosphate 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionFamotidine 2 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionFentanyl citrate 50 µg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionFluconazole 2 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionFluorouracil 16 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionFolinate calcium 2 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionFurosemide 3 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionGanciclovir sodium 20 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionGemcitabine hydrochloride 10 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionGentamicin sulfate 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionHeparin sodium 100 UI/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionHydrocortisone sodium succinate 1 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionHydromorphone hydrochloride 0.5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionIfosfamide 25 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionImipenem - cilastatin sodium 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionLevofloxacine 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionLinezolid 2 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionMeropenem 2.5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionMethylprednisolone sodium succinate 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionMetronidazole 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionMidazolam hydrochloride 1 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionMorphine sulfate 15 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionMycophenolate mofetil 6 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionPaclitaxel 0.6 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionPantoprazole sodium 0.4 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionPhenylephrine hydrochloride 1 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionPiperacillin sodium / tazobactam 40/5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionPotassium chloride 0.1 mEq/l + Glucose 5%
Compatible 0.5 mg/ml + injectionQuinupristine/dalfopristine 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionRanitidine hydrochloride 2 mg/ml + Glucose 5%
Incompatible 0.5 mg/ml + injectionSodium bicarbonate 84 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionTacrolimus 20 µg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionTicarcillin / clavulanic acid 31 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionTobramycin sulfate 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionVincristine sulfate 0.05 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionVoriconazole 4 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + injectionZidovudine 4 mg/ml + Glucose 5%
Incompatible 0.5 mg/ml + NaHCO3
injectionCarboplatin Anticancer drug
Compatible 5 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionCefazolin sodium Antibiotic
Compatible 20 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionCefepime dihydrochloride Antibiotic
Compatible 20 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionCefoxitin sodium Antibiotic
Compatible 20 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionCeftazidime Antibiotic
Compatible 40 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionCeftizoxime sodium Antibiotic
Compatible 20 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionCeftriaxone disodium Antibiotic
Compatible 20 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionCefuroxime sodium Antibiotic
Compatible 30 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionCiclosporin Immunosuppressant
Compatible 5 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionCimetidine hydrochloride Antihistamine (H2)
Compatible 12 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionCiprofloxacin lactate Antibiotic
Compatible 2 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionCisplatin Anticancer drug
Compatible 1 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionClindamycin phosphate Antibiotic
Compatible 10 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionCo-trimoxazole Antibiotic
Compatible 4/0.8 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionCyclophosphamide Anticancer drug
Compatible 10 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionCytarabine Anticancer drug
Compatible 50 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionDaunorubicin hydrochloride Anticancer drug
Compatible 1 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 1 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionDigoxin Cardiotonic
Compatible 250 µg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionDobutamine hydrochloride Cardiotonic
Compatible 4 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionDocetaxel Anticancer drug
Compatible 2 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionDopamine hydrochloride Cardiotonic
Compatible 3.2 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionDoxorubicin hydrochloride Anticancer drug
Compatible 2 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionEpinephrine hydrochloride Sympathomimetic
Compatible 50 µg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionErtapenem Antibiotic
Incompatible 20 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionErythromycin lactobionate Antibiotic
Compatible 5 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionEtoposide phosphate Anticancer drug
Compatible 5 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionFamotidine Antihistamine (H2)
Compatible 2 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionFentanyl citrate Analgesic
Compatible 50 µg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionFluconazole Antifungal
Compatible 2 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionFluorouracil Anticancer drug
Compatible 16 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionFolinate calcium Cytoprotective
Compatible 2 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionFurosemide Diuretic
Compatible 3 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionGanciclovir sodium Antiviral
Compatible 20 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionGemcitabine hydrochloride Anticancer drug
Compatible 10 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionGentamicin sulfate Antibiotic
Compatible 5 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionHeparin sodium Anticoagulant
Compatible 100 UI/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 1 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionHydromorphone hydrochloride Analgesic
Compatible 0.5 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionIfosfamide Anticancer drug
Compatible 25 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionImipenem - cilastatin sodium Antibiotic
Compatible 5 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionLevofloxacine Antibiotic
Compatible 5 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionLinezolid Antibiotic
Compatible 2 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionMeropenem Antibiotic
Compatible 2.5 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionMethylprednisolone sodium succinate Anti-inflammatory
Compatible 5 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionMetronidazole Antiparasitic
Compatible 5 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionMidazolam hydrochloride Anxiolytic
Compatible 1 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionMorphine sulfate Analgesic
Compatible 15 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionMycophenolate mofetil Immunosuppressant
Compatible 6 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionPaclitaxel Anticancer drug
Compatible 0.6 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionPantoprazole sodium Proton pump inhibitor
Compatible 0.4 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionPethidine hydrochloride Analgesic
Compatible 10 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionPhenylephrine hydrochloride Sympathomimetic
Compatible 1 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionPiperacillin sodium / tazobactam Antibiotic
Compatible 40/5 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionPotassium chloride Electrolyte
Compatible 0.1 mEq/l + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionQuinupristine/dalfopristine Antibiotic
Compatible 5 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionRanitidine hydrochloride Antihistamine (H2)
Compatible 2 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionSodium bicarbonate Electrolyte
Incompatible 84 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionTacrolimus Immunosuppressant
Compatible 20 µg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionTicarcillin / clavulanic acid Antibiotic
Compatible 31 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionTobramycin sulfate Antibiotic
Compatible 5 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionVancomycin hydrochloride Antibiotic
Compatible 10 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionVincristine sulfate Anticancer drug
Compatible 0.05 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionVoriconazole Antifungal
Compatible 4 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%
injectionZidovudine Antiviral
Compatible 4 mg/ml + injectionAnidulafungin 0.5 mg/ml + Glucose 5%

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