Last update :
07/10/2024
References   References 3385  
Type : Journal
Web link : https://doi.org/10.1093/jac/dks510
Icone.pdf
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Research teams : Mont Godinne - Drug Stability Research Group (DSRG) - CHU UCL NAMUR, site de Godinne
Authors : Raverdi V, Ampe E, Hecq JD, Tulkens PM.
Title : Stability and compatibility of vancomycin for administration by continuous infusion.
Reference : J Antimicrob Chemother ; 68: 1179-1182. 2013

Level of Evidence : 
Physical stability : 
Visual examination Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Other methods : 
Comments : 

List of drugs
injectionAmikacin sulfate Antibiotic
Compatible 15 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionCefepime dihydrochloride Antibiotic
Compatible 83.33 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
Incompatible 200 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionCeftazidime Antibiotic
Incompatible 125 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionCiprofloxacin lactate Antibiotic
Compatible 2 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionDobutamine hydrochloride Cardiotonic
Compatible 1 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionDopamine hydrochloride Cardiotonic
Compatible 0.4 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionEpinephrine hydrochloride Sympathomimetic
Compatible 50 µg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionErythromycin lactobionate Antibiotic
Compatible 5 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionFlucloxacillin sodium Antibiotic
Incompatible 250 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionFluconazole Antifungal
Compatible 2 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionFurosemide Diuretic
Incompatible 10 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionGentamicin sulfate Antibiotic
Compatible 6 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionInsulin Glucose-lowering
Compatible 100 UI/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionIsosorbide dinitrate Vasodilator
Compatible 0.2 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionKetamine hydrochloride General anesthetic
Compatible 10 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionMidazolam hydrochloride Anxiolytic
Compatible 5 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionMoxifloxacin Antibiotic
Incompatible 1.6 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionN-acetylcysteine Antidote
Compatible 100 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionNicardipine hydrochloride Vasodilator
Compatible 1 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionPhenytoin sodium Antiepileptic
Incompatible 50 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionPiperacillin sodium / tazobactam Antibiotic
Incompatible 200 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionPiritramide Analgesic
Compatible 2 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionPropofol General anesthetic
Incompatible 1 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionSufentanil citrate Analgesic
Compatible 0.005 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionTemocilline Antibiotic
Incompatible 100 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionTheophylline Various
Incompatible 20 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionTobramycin sulfate Antibiotic
Compatible 6 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionUrapidil Antihypertensive
Compatible 5 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionValproic acid Antiepileptic
Incompatible 100 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionVancomycin hydrochloride Antibiotic
Compatible 10 mg/ml + injectionAmikacin sulfate 15 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionCefepime dihydrochloride 83.33 mg/ml + Glucose 5%
Incompatible 10 mg/ml + injectionCefepime dihydrochloride 200 mg/ml + Glucose 5%
Incompatible 10 mg/ml + injectionCeftazidime 125 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionDobutamine hydrochloride 1 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionDopamine hydrochloride 0.4 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionEpinephrine hydrochloride 50 µg/ml + Glucose 5%
Compatible 10 mg/ml + injectionErythromycin lactobionate 5 mg/ml + Glucose 5%
Incompatible 10 mg/ml + injectionFlucloxacillin sodium 250 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionFluconazole 2 mg/ml + Glucose 5%
Incompatible 10 mg/ml + injectionFurosemide 10 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionGentamicin sulfate 6 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionInsulin 100 UI/ml + Glucose 5%
Compatible 10 mg/ml + injectionIsosorbide dinitrate 0.2 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionKetamine hydrochloride 10 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionMidazolam hydrochloride 5 mg/ml + Glucose 5%
Incompatible 10 mg/ml + injectionMoxifloxacin 1.6 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionN-acetylcysteine 100 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionNicardipine hydrochloride 1 mg/ml + Glucose 5%
Incompatible 10 mg/ml + injectionPhenytoin sodium 50 mg/ml + Glucose 5%
Incompatible 10 mg/ml + injectionPiperacillin sodium / tazobactam 200 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionPiritramide 2 mg/ml + Glucose 5%
Incompatible 10 mg/ml + injectionPropofol 1 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionSufentanil citrate 0.005 mg/ml + Glucose 5%
Incompatible 10 mg/ml + injectionTemocilline 100 mg/ml + Glucose 5%
Incompatible 10 mg/ml + injectionTheophylline 20 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionTobramycin sulfate 6 mg/ml + Glucose 5%
Compatible 10 mg/ml + injectionUrapidil 5 mg/ml + Glucose 5%
Incompatible 10 mg/ml + injectionValproic acid 100 mg/ml + Glucose 5%

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