Last update :
08/12/2024
References   References 3964  
Type : Journal
Web link : http://www.pharmactuel.com/index.php/pharmactuel/article/view/1129

Research teams : Montreal - Centre hospitalier Sainte Justine
Authors : Audet M.A, Forest E, Friciu M, Forest J.M, Leclair G.
Title : Compatibilité du citrate de caféine injectable avec plusieurs autres médicaments.
Reference : Pharmactuel ; 50,1 : 27-33. 2017

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
injectionAciclovir sodium Antiviral
Compatible 50 mg/ml + injectionCaffeine 10 mg/ml + None
injectionAmikacin sulfate Antibiotic
Compatible 250 mg/ml + injectionCaffeine 10 mg/ml + None
injectionAmiodarone hydrochloride Anti-arrhythmic
Incompatible 50 mg/ml + injectionCaffeine 10 mg/ml + None
injectionAmphotericin B liposomale Antifungal
Compatible 4 mg/ml + injectionCaffeine 10 mg/ml + None
injectionAmpicillin sodium Antibiotic
Compatible 100 mg/ml + injectionCaffeine 10 mg/ml + None
injectionAtropine sulfate Antimuscarinic
Compatible 0.4 mg/ml + injectionCaffeine 10 mg/ml + None
injectionAzithromycine Antibiotic
Compatible 100 mg/ml + injectionCaffeine 10 mg/ml + None
injectionBenztropine mesylate Antimuscarinic
Compatible 1 mg/ml + injectionCaffeine 10 mg/ml + None
injectionBretylium tosilate Anti-arrhythmic
Compatible 50 mg/ml + injectionCaffeine 10 mg/ml + None
injectionBupivacaine hydrochloride Local anesthetic
Compatible 5 mg/ml + injectionCaffeine 10 mg/ml + None
injectionCaffeine Respiratory stimulant
Compatible 10 mg/ml + injectionAciclovir sodium 50 mg/ml + None
Compatible 10 mg/ml + injectionAmikacin sulfate 250 mg/ml + None
Incompatible 10 mg/ml + injectionAmiodarone hydrochloride 50 mg/ml + None
Compatible 10 mg/ml + injectionAmphotericin B liposomale 4 mg/ml + None
Compatible 10 mg/ml + injectionAmpicillin sodium 100 mg/ml + None
Compatible 10 mg/ml + injectionAtropine sulfate 0.4 mg/ml + None
Compatible 10 mg/ml + injectionAzithromycine 100 mg/ml + None
Compatible 10 mg/ml + injectionBenztropine mesylate 1 mg/ml + None
Compatible 10 mg/ml + injectionBretylium tosilate 50 mg/ml + None
Compatible 10 mg/ml + injectionBupivacaine hydrochloride 5 mg/ml + None
Compatible 10 mg/ml + injectionCalcium chloride 100 mg/ml + None
Compatible 10 mg/ml + injectionCalcium gluconate 100 mg/ml + None
Incompatible 10 mg/ml + injectionCaspofungin acetate 5 mg/ml + None
Compatible 10 mg/ml + injectionCefazolin sodium 100 mg/ml + None
Compatible 10 mg/ml + injectionCefotaxime sodium 100 mg/ml + None
Compatible 10 mg/ml + injectionCefoxitin sodium 100 mg/ml + None
Compatible 10 mg/ml + injectionCeftazidime 100 mg/ml + None
Compatible 10 mg/ml + injectionCeftriaxone disodium 100 mg/ml + None
Compatible 10 mg/ml + injectionCefuroxime sodium 100 mg/ml + None
Compatible 10 mg/ml + injectionChlorpromazine hydrochloride 25 mg/ml + None
Incompatible 10 mg/ml + injectionCiprofloxacin lactate 2 mg/ml + None
Compatible 10 mg/ml + injectionClindamycin phosphate 150 mg/ml + None
Compatible 10 mg/ml + injectionCloxacillin sodium 100 mg/ml + None
Compatible 10 mg/ml + injectionCo-trimoxazole 16/80 mg/ml + None
Compatible 10 mg/ml + injectionDexamethasone sodium phosphate 4 mg/ml + None
Compatible 10 mg/ml + injectionDexmedetomidine 100 µg/ml + None
Incompatible 10 mg/ml + injectionDiazepam 5 mg/ml + None
Compatible 10 mg/ml + injectionDigoxin 250 µg/ml + None
Compatible 10 mg/ml + injectionDimenhydrinate 10 mg/ml + None
Compatible 10 mg/ml + injectionDiphenhydramine hydrochloride 50 mg/ml + None
Incompatible 10 mg/ml + injectionDipyridamol 5 mg/ml + None
Incompatible 10 mg/ml + injectionDobutamine hydrochloride 12.5 mg/ml + None
Incompatible 10 mg/ml + injectionDopamine hydrochloride 3.2 mg/ml + None
Incompatible 10 mg/ml + injectionDroperidol 2.5 mg/ml + None
Compatible 10 mg/ml + injectionEpinephrine hydrochloride 100 µg/ml + None
Incompatible 10 mg/ml + injectionErythromycin lactobionate 50 mg/ml + None
Compatible 10 mg/ml + injectionEsmolol hydrochloride 10 mg/ml + None
Compatible 10 mg/ml + injectionFentanyl citrate 50 µg/ml + None
Compatible 10 mg/ml + injectionFluconazole 2 mg/ml + None
Compatible 10 mg/ml + injectionFurosemide 10 mg/ml + None
Compatible 10 mg/ml + injectionGentamicin sulfate 10 mg/ml + None
Compatible 10 mg/ml + injectionGranisetron hydrochloride 1 mg/ml + None
Compatible 10 mg/ml + injectionHeparin sodium 1000 UI/ml + None
Compatible 10 mg/ml + injectionHuman albumin 250 mg/ml + None
Compatible 10 mg/ml + injectionHydralazine hydrochloride 20 mg/ml + None
Compatible 10 mg/ml + injectionHydrocortisone sodium succinate 250 mg/ml + None
Compatible 10 mg/ml + injectionHydromorphone hydrochloride 50 mg/ml + None
Incompatible 10 mg/ml + injectionHydroxyzine dihydrochloride 50 mg/ml + None
Compatible 10 mg/ml + injectionInsulin 100 UI/ml + None
Incompatible 10 mg/ml + injectionIsoprenaline hydrochloride 0.2 mg/ml + None
Compatible 10 mg/ml + injectionKetamine hydrochloride 50 mg/ml + None
Compatible 10 mg/ml + injectionLabetalol hydrochloride 5 mg/ml + None
Compatible 10 mg/ml + injectionLevofloxacine 5 mg/ml + None
Compatible 10 mg/ml + injectionLidocaine hydrochloride 10 mg/ml + None
Compatible 10 mg/ml + injectionLinezolid 2 mg/ml + None
Incompatible 10 mg/ml + injectionLorazepam 4 mg/ml + None
Compatible 10 mg/ml + injectionMagnesium sulfate 500 mg/ml + None
Compatible 10 mg/ml + injectionMannitol 250 mg/ml + None
Compatible 10 mg/ml + injectionMeropenem 50 mg/ml + None
Compatible 10 mg/ml + injectionMethylprednisolone sodium succinate 500 mg/ml + None
Compatible 10 mg/ml + injectionMetoclopramide hydrochloride 5 mg/ml + None
Compatible 10 mg/ml + injectionMetronidazole 5 mg/ml + None
Incompatible 10 mg/ml + injectionMidazolam hydrochloride 5 mg/ml + None
Compatible 10 mg/ml + injectionMilrinone lactate 1 mg/ml + None
Compatible 10 mg/ml + injectionMorphine sulfate 50 mg/ml + None
Compatible 10 mg/ml + injectionN-acetylcysteine 200 mg/ml + None
Compatible 10 mg/ml + injectionNaloxone hydrochloride 0.4 mg/ml + None
Incompatible 10 mg/ml + injectionNitroglycerin 5 mg/ml + None
Compatible 10 mg/ml + injectionNitroprusside sodium 25 mg/ml + None
Compatible 10 mg/ml + injectionNorepinephrine bitartrate 1 mg/ml + None
Compatible 10 mg/ml + injectionOndansetron hydrochloride 2 mg/ml + None
Compatible 10 mg/ml + injectionOxytocin 10 UI/ml + None
Compatible 10 mg/ml + injectionPantoprazole sodium 40 mg/ml + None
Compatible 10 mg/ml + injectionPenicillin G sodium 0.5 MUI/ml + None
Compatible 10 mg/ml + injectionPhenytoin sodium 50 mg/ml + None
Compatible 10 mg/ml + injectionPiperacillin sodium 200 mg/ml + None
Compatible 10 mg/ml + injectionPiperacillin sodium / tazobactam 200 mg/ml + None
Compatible 10 mg/ml + injectionPotassium chloride 200 mEq/l + None
Incompatible 10 mg/ml + injectionPotassium phosphate 4.4 mmol/ml + None
Compatible 10 mg/ml + injectionProcainamide hydrochloride 100 mg/ml + None
Compatible 10 mg/ml + injectionPromethazine hydrochloride 25 mg/ml + None
Compatible 10 mg/ml + injectionPropranolol hydrochloride 1 mg/ml + None
Compatible 10 mg/ml + injectionRanitidine hydrochloride 25 mg/ml + None
Compatible 10 mg/ml + injectionRocuronium bromide 10 mg/ml + None
Compatible 10 mg/ml + injectionSalbutamol sulfate 1 mg/ml + None
Compatible 10 mg/ml + injectionSodium bicarbonate 84 mg/ml + None
Incompatible 10 mg/ml + injectionSodium Phosphate 3 mmol/ml + None
Compatible 10 mg/ml + injectionSufentanil citrate 0.05 mg/ml + None
Compatible 10 mg/ml + injectionTicarcillin / clavulanic acid 200 mg/ml + None
Compatible 10 mg/ml + injectionTobramycin sulfate 40 mg/ml + None
Incompatible 10 mg/ml + injectionVancomycin hydrochloride 50 mg/ml + None
Compatible 10 mg/ml + injectionVoriconazole 10 mg/ml + None
injectionCalcium chloride Electrolyte
Compatible 100 mg/ml + injectionCaffeine 10 mg/ml + None
injectionCalcium gluconate Electrolyte
Compatible 100 mg/ml + injectionCaffeine 10 mg/ml + None
injectionCaspofungin acetate Antifungal
Incompatible 5 mg/ml + injectionCaffeine 10 mg/ml + None
injectionCefazolin sodium Antibiotic
Compatible 100 mg/ml + injectionCaffeine 10 mg/ml + None
injectionCefotaxime sodium Antibiotic
Compatible 100 mg/ml + injectionCaffeine 10 mg/ml + None
injectionCefoxitin sodium Antibiotic
Compatible 100 mg/ml + injectionCaffeine 10 mg/ml + None
injectionCeftazidime Antibiotic
Compatible 100 mg/ml + injectionCaffeine 10 mg/ml + None
injectionCeftriaxone disodium Antibiotic
Compatible 100 mg/ml + injectionCaffeine 10 mg/ml + None
injectionCefuroxime sodium Antibiotic
Compatible 100 mg/ml + injectionCaffeine 10 mg/ml + None
injectionChlorpromazine hydrochloride Anxiolytic
Compatible 25 mg/ml + injectionCaffeine 10 mg/ml + None
injectionCiprofloxacin lactate Antibiotic
Incompatible 2 mg/ml + injectionCaffeine 10 mg/ml + None
injectionClindamycin phosphate Antibiotic
Compatible 150 mg/ml + injectionCaffeine 10 mg/ml + None
injectionCloxacillin sodium Antibiotic
Compatible 100 mg/ml + injectionCaffeine 10 mg/ml + None
injectionCo-trimoxazole Antibiotic
Compatible 16/80 mg/ml + injectionCaffeine 10 mg/ml + None
injectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 4 mg/ml + injectionCaffeine 10 mg/ml + None
injectionDexmedetomidine Sympathomimetic
Compatible 100 µg/ml + injectionCaffeine 10 mg/ml + None
injectionDiazepam Anxiolytic
Incompatible 5 mg/ml + injectionCaffeine 10 mg/ml + None
injectionDigoxin Cardiotonic
Compatible 250 µg/ml + injectionCaffeine 10 mg/ml + None
injectionDimenhydrinate Antihistamine (H1)
Compatible 10 mg/ml + injectionCaffeine 10 mg/ml + None
injectionDiphenhydramine hydrochloride Antihistamine (H1)
Compatible 50 mg/ml + injectionCaffeine 10 mg/ml + None
injectionDipyridamol Vasodilator
Incompatible 5 mg/ml + injectionCaffeine 10 mg/ml + None
injectionDobutamine hydrochloride Cardiotonic
Incompatible 12.5 mg/ml + injectionCaffeine 10 mg/ml + None
injectionDopamine hydrochloride Cardiotonic
Incompatible 3.2 mg/ml + injectionCaffeine 10 mg/ml + None
injectionDroperidol Neuroleptic
Incompatible 2.5 mg/ml + injectionCaffeine 10 mg/ml + None
injectionEpinephrine hydrochloride Sympathomimetic
Compatible 100 µg/ml + injectionCaffeine 10 mg/ml + None
injectionErythromycin lactobionate Antibiotic
Incompatible 50 mg/ml + injectionCaffeine 10 mg/ml + None
injectionEsmolol hydrochloride Beta-blocker
Compatible 10 mg/ml + injectionCaffeine 10 mg/ml + None
injectionFentanyl citrate Analgesic
Compatible 50 µg/ml + injectionCaffeine 10 mg/ml + None
injectionFluconazole Antifungal
Compatible 2 mg/ml + injectionCaffeine 10 mg/ml + None
injectionFurosemide Diuretic
Compatible 10 mg/ml + injectionCaffeine 10 mg/ml + None
injectionGentamicin sulfate Antibiotic
Compatible 10 mg/ml + injectionCaffeine 10 mg/ml + None
injectionGranisetron hydrochloride Antiemetic
Compatible 1 mg/ml + injectionCaffeine 10 mg/ml + None
injectionHeparin sodium Anticoagulant
Compatible 1000 UI/ml + injectionCaffeine 10 mg/ml + None
injectionHuman albumin Various
Compatible 250 mg/ml + injectionCaffeine 10 mg/ml + None
injectionHydralazine hydrochloride Antihypertensive
Compatible 20 mg/ml + injectionCaffeine 10 mg/ml + None
injectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 250 mg/ml + injectionCaffeine 10 mg/ml + None
injectionHydromorphone hydrochloride Analgesic
Compatible 50 mg/ml + injectionCaffeine 10 mg/ml + None
injectionHydroxyzine dihydrochloride Anxiolytic
Incompatible 50 mg/ml + injectionCaffeine 10 mg/ml + None
injectionInsulin Glucose-lowering
Compatible 100 UI/ml + injectionCaffeine 10 mg/ml + None
injectionIsoprenaline hydrochloride Beta-stimulant
Incompatible 0.2 mg/ml + injectionCaffeine 10 mg/ml + None
injectionKetamine hydrochloride General anesthetic
Compatible 50 mg/ml + injectionCaffeine 10 mg/ml + None
injectionLabetalol hydrochloride Beta-blocker
Compatible 5 mg/ml + injectionCaffeine 10 mg/ml + None
injectionLevofloxacine Antibiotic
Compatible 5 mg/ml + injectionCaffeine 10 mg/ml + None
injectionLidocaine hydrochloride Local anesthetic
Compatible 10 mg/ml + injectionCaffeine 10 mg/ml + None
injectionLinezolid Antibiotic
Compatible 2 mg/ml + injectionCaffeine 10 mg/ml + None
injectionLorazepam Anxiolytic
Incompatible 4 mg/ml + injectionCaffeine 10 mg/ml + None
injectionMagnesium sulfate Electrolyte
Compatible 500 mg/ml + injectionCaffeine 10 mg/ml + None
injectionMannitol Various
Compatible 250 mg/ml + injectionCaffeine 10 mg/ml + None
injectionMeropenem Antibiotic
Compatible 50 mg/ml + injectionCaffeine 10 mg/ml + None
injectionMethylprednisolone sodium succinate Anti-inflammatory
Compatible 500 mg/ml + injectionCaffeine 10 mg/ml + None
injectionMetoclopramide hydrochloride Antiemetic
Compatible 5 mg/ml + injectionCaffeine 10 mg/ml + None
injectionMetronidazole Antiparasitic
Compatible 5 mg/ml + injectionCaffeine 10 mg/ml + None
injectionMidazolam hydrochloride Anxiolytic
Incompatible 5 mg/ml + injectionCaffeine 10 mg/ml + None
injectionMilrinone lactate Cardiotonic
Compatible 1 mg/ml + injectionCaffeine 10 mg/ml + None
injectionMorphine sulfate Analgesic
Compatible 50 mg/ml + injectionCaffeine 10 mg/ml + None
injectionN-acetylcysteine Antidote
Compatible 200 mg/ml + injectionCaffeine 10 mg/ml + None
injectionNaloxone hydrochloride Antidote
Compatible 0.4 mg/ml + injectionCaffeine 10 mg/ml + None
injectionNitroglycerin Vasodilator
Incompatible 5 mg/ml + injectionCaffeine 10 mg/ml + None
injectionNitroprusside sodium Vasodilator
Compatible 25 mg/ml + injectionCaffeine 10 mg/ml + None
injectionNorepinephrine bitartrate Sympathomimetic
Compatible 1 mg/ml + injectionCaffeine 10 mg/ml + None
injectionOndansetron hydrochloride Antiemetic
Compatible 2 mg/ml + injectionCaffeine 10 mg/ml + None
injectionOxytocin Various
Compatible 10 UI/ml + injectionCaffeine 10 mg/ml + None
injectionPantoprazole sodium Proton pump inhibitor
Compatible 40 mg/ml + injectionCaffeine 10 mg/ml + None
injectionPenicillin G sodium Antibiotic
Compatible 0.5 MUI/ml + injectionCaffeine 10 mg/ml + None
injectionPhenytoin sodium Antiepileptic
Compatible 50 mg/ml + injectionCaffeine 10 mg/ml + None
injectionPiperacillin sodium Antibiotic
Compatible 200 mg/ml + injectionCaffeine 10 mg/ml + None
injectionPiperacillin sodium / tazobactam Antibiotic
Compatible 200 mg/ml + injectionCaffeine 10 mg/ml + None
injectionPotassium chloride Electrolyte
Compatible 200 mEq/l + injectionCaffeine 10 mg/ml + None
injectionPotassium phosphate Electrolyte
Incompatible 4.4 mmol/ml + injectionCaffeine 10 mg/ml + None
injectionProcainamide hydrochloride Anti-arrhythmic
Compatible 100 mg/ml + injectionCaffeine 10 mg/ml + None
injectionPromethazine hydrochloride Antihistamine (H1)
Compatible 25 mg/ml + injectionCaffeine 10 mg/ml + None
injectionPropranolol hydrochloride Beta-blocker
Compatible 1 mg/ml + injectionCaffeine 10 mg/ml + None
injectionRanitidine hydrochloride Antihistamine (H2)
Compatible 25 mg/ml + injectionCaffeine 10 mg/ml + None
injectionRocuronium bromide Curarimimetic
Compatible 10 mg/ml + injectionCaffeine 10 mg/ml + None
injectionSalbutamol sulfate Beta-stimulant
Compatible 1 mg/ml + injectionCaffeine 10 mg/ml + None
injectionSodium bicarbonate Electrolyte
Compatible 84 mg/ml + injectionCaffeine 10 mg/ml + None
injectionSodium Phosphate Electrolyte
Incompatible 3 mmol/ml + injectionCaffeine 10 mg/ml + None
injectionSufentanil citrate Analgesic
Compatible 0.05 mg/ml + injectionCaffeine 10 mg/ml + None
injectionTicarcillin / clavulanic acid Antibiotic
Compatible 200 mg/ml + injectionCaffeine 10 mg/ml + None
injectionTobramycin sulfate Antibiotic
Compatible 40 mg/ml + injectionCaffeine 10 mg/ml + None
injectionVancomycin hydrochloride Antibiotic
Incompatible 50 mg/ml + injectionCaffeine 10 mg/ml + None
injectionVoriconazole Antifungal
Compatible 10 mg/ml + injectionCaffeine 10 mg/ml + None

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