Last update :
09/04/2024
References   References 496  
Type : Journal

Research teams : Los Angeles - USC/Norris Cancer Center
Authors : Lor E, Sheybani T, Takagi J.
Title : Visual compatibility of fluconazole with commonly used injectable drugs during simulated Y-site administration.
Reference : Am J Hosp Pharm ; 48: 744-746. 1991

Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Not rated: compatibility study only

List of drugs
InjectionAciclovir sodium Antiviral
Compatible 10 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionAmikacin sulfate Antibiotic
Compatible 20 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionAminophylline Various
Compatible 25 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionAmphotericin B Antifungal
Incompatible 5 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionAmpicillin sodium Antibiotic
Incompatible 20 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionAmpicillin sodium - sulbactam sodium Antibiotic
Compatible 60 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionAztreonam Antibiotic
Compatible 40 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionBenztropine mesylate Antimuscarinic
Compatible 1 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionCalcium gluconate Electrolyte
Incompatible 100 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionCefazolin sodium Antibiotic
Compatible 40 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionCefotaxime sodium Antibiotic
Incompatible 20 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionCefoxitin sodium Antibiotic
Compatible 40 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionCeftazidime Antibiotic
Incompatible 20 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionCeftriaxone disodium Antibiotic
Incompatible 40 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionCefuroxime sodium Antibiotic
Incompatible 30 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionChloramphenicol sodium succinate Antibiotic
Incompatible 20 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionChlorpromazine hydrochloride Anxiolytic
Compatible 25 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionCimetidine hydrochloride Antihistamine (H2)
Compatible 150 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionClindamycin phosphate Antibiotic
Incompatible 24 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionCo-trimoxazole Antibiotic
Incompatible 16 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 4 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionDiazepam Anxiolytic
Incompatible 5 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionDigoxin Cardiotonic
Incompatible 250 µg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionDiphenhydramine hydrochloride Antihistamine (H1)
Compatible 50 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionDroperidol Neuroleptic
Compatible 2.5 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionErythromycin lactobionate Antibiotic
Incompatible 20 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionFamotidine Antihistamine (H2)
Compatible 10 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionFluconazole Antifungal
Compatible 2 mg/ml + InjectionAciclovir sodium 10 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionAmikacin sulfate 20 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionAminophylline 25 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + InjectionAmphotericin B 5 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + InjectionAmpicillin sodium 20 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionAmpicillin sodium - sulbactam sodium 60 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionAztreonam 40 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionBenztropine mesylate 1 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + InjectionCalcium gluconate 100 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionCefazolin sodium 40 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + InjectionCefotaxime sodium 20 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionCefoxitin sodium 40 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + InjectionCeftazidime 20 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + InjectionCeftriaxone disodium 40 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + InjectionCefuroxime sodium 30 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + InjectionChloramphenicol sodium succinate 20 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionChlorpromazine hydrochloride 25 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionCimetidine hydrochloride 150 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + InjectionClindamycin phosphate 24 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + InjectionCo-trimoxazole 16 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionDexamethasone sodium phosphate 4 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + InjectionDiazepam 5 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + InjectionDigoxin 250 µg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionDiphenhydramine hydrochloride 50 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionDroperidol 2.5 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + InjectionErythromycin lactobionate 20 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionFamotidine 10 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionFolinate calcium 10 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionFoscarnet sodium 24 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + InjectionFurosemide 10 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionGanciclovir sodium 50 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionGentamicin sulfate 4 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + InjectionHaloperidol lactate 5 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionHeparin sodium 1000 UI/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + InjectionHydroxyzine dihydrochloride 50 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + InjectionImipenem - cilastatin sodium 10 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionMetoclopramide hydrochloride 5 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionMetronidazole 5 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionMidazolam hydrochloride 5 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionMorphine sulfate 25 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionNafcillin sodium 20 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionOxacillin sodium 40 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionPenicillin G potassium 0.1 MUI/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + InjectionPentamidine isetionate 6 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionPhenytoin sodium 50 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + InjectionPiperacillin sodium 80 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionProchlorperazine edysilate 5 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionPromethazine hydrochloride 50 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionTicarcillin / clavulanic acid 60 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionTobramycin sulfate 40 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionVancomycin hydrochloride 20 mg/ml + Sodium chloride 0,9%
Compatible 2 mg/ml + InjectionZidovudine 10 mg/ml + Sodium chloride 0,9%
InjectionFolinate calcium Cytoprotective
Compatible 10 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionFoscarnet sodium Antiviral
Compatible 24 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionFurosemide Diuretic
Incompatible 10 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionGanciclovir sodium Antiviral
Compatible 50 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionGentamicin sulfate Antibiotic
Compatible 4 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionHaloperidol lactate Neuroleptic
Incompatible 5 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionHeparin sodium Anticoagulant
Compatible 1000 UI/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionHydroxyzine dihydrochloride Anxiolytic
Incompatible 50 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionImipenem - cilastatin sodium Antibiotic
Incompatible 10 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionMetoclopramide hydrochloride Antiemetic
Compatible 5 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionMetronidazole Antiparasitic
Compatible 5 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionMidazolam hydrochloride Anxiolytic
Compatible 5 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionMorphine sulfate Analgesic
Compatible 25 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionNafcillin sodium Antibiotic
Compatible 20 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionOxacillin sodium Antibiotic
Compatible 40 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionPenicillin G potassium Antibiotic
Compatible 0.1 MUI/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionPentamidine isetionate Antibiotic
Incompatible 6 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionPhenytoin sodium Antiepileptic
Compatible 50 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionPiperacillin sodium Antibiotic
Incompatible 80 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionProchlorperazine edysilate Neuroleptic
Compatible 5 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionPromethazine hydrochloride Antihistamine (H1)
Compatible 50 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionTicarcillin / clavulanic acid Antibiotic
Compatible 60 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionTobramycin sulfate Antibiotic
Compatible 40 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionVancomycin hydrochloride Antibiotic
Compatible 20 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%
InjectionZidovudine Antiviral
Compatible 10 mg/ml + InjectionFluconazole 2 mg/ml + Sodium chloride 0,9%

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