Last update :
21/02/2024
References   References 3012  
Type : Journal
Web link : http://thomasland.metapress.com/content/t517j7328u2q050t/?p=221f2066496a49958fc59ac24441ed0e&pi=8

Research teams : Montreal - Jewish General Hospital, Pharmacy Department
Authors : Sullivan T, Forrest J.M, Leclair G.
Title : Compatibility of Cloxacillin Sodium with Selected Intravenous Drugs During Simulated Y-Site Administration
Reference : Hosp Pharm ; 50, 3: 214-220. 2015

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
InjectionAciclovir sodium Antiviral
Compatible 50 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionAmikacin sulfate Antibiotic
Incompatible 250 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionAmiodarone hydrochloride Anti-arrhythmic
Compatible 50 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionAmphotericin B liposomale Antifungal
Compatible 4 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionAmpicillin sodium Antibiotic
Compatible 250 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionAtropine sulfate Antimuscarinic
Compatible 0.4 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionAzithromycine Antibiotic
Incompatible 100 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionBenztropine mesylate Antimuscarinic
Compatible 1 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionCalcium chloride Electrolyte
Compatible 100 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionCalcium gluconate Electrolyte
Compatible 100 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionCaspofungin acetate Antifungal
Compatible 5 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionCefazolin sodium Antibiotic
Compatible 10 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionCefotaxime sodium Antibiotic
Compatible 95 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionCefoxitin sodium Antibiotic
Compatible 100 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionCeftazidime Antibiotic
Compatible 95 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionCeftriaxone disodium Antibiotic
Compatible 100 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionCefuroxime sodium Antibiotic
Compatible 90 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionChlorpromazine hydrochloride Anxiolytic
Incompatible 25 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionCiclosporin Immunosuppressant
Compatible 5 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionCiprofloxacin lactate Antibiotic
Incompatible 2 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionClindamycin phosphate Antibiotic
Compatible 150 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionCloxacillin sodium Antibiotic
Compatible 100 mg/ml + InjectionAciclovir sodium 50 mg/ml + Water for Injection
Incompatible 100 mg/ml + InjectionAmikacin sulfate 250 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionAmiodarone hydrochloride 50 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionAmphotericin B liposomale 4 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionAmpicillin sodium 250 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionAtropine sulfate 0.4 mg/ml + Water for Injection
Incompatible 100 mg/ml + InjectionAzithromycine 100 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionBenztropine mesylate 1 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionCalcium chloride 100 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionCalcium gluconate 100 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionCaspofungin acetate 5 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionCefazolin sodium 10 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionCefotaxime sodium 95 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionCefoxitin sodium 100 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionCeftazidime 95 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionCeftriaxone disodium 100 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionCefuroxime sodium 90 mg/ml + Water for Injection
Incompatible 100 mg/ml + InjectionChlorpromazine hydrochloride 25 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionCiclosporin 5 mg/ml + Water for Injection
Incompatible 100 mg/ml + InjectionCiprofloxacin lactate 2 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionClindamycin phosphate 150 mg/ml + Water for Injection
Incompatible 100 mg/ml + InjectionCo-trimoxazole 80/16 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionDexamethasone sodium phosphate 4 mg/ml + Water for Injection
Incompatible 100 mg/ml + InjectionDiazepam 5 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionDigoxin 50 µg/ml + Water for Injection
Compatible 100 mg/ml + InjectionDimenhydrinate 10 mg/ml + Water for Injection
Incompatible 100 mg/ml + InjectionDiphenhydramine hydrochloride 50 mg/ml + Water for Injection
Incompatible 100 mg/ml + InjectionDobutamine hydrochloride 12,5 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionDopamine hydrochloride 3.2 mg/ml + Water for Injection
Incompatible 100 mg/ml + InjectionDroperidol 2,5 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionEpinephrine hydrochloride 100 µg/ml + Water for Injection
Compatible 100 mg/ml + InjectionEpinephrine hydrochloride 1000 µg/ml + Water for Injection
Incompatible 100 mg/ml + InjectionErythromycin lactobionate 50 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionEsmolol hydrochloride 10 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionFentanyl citrate 50 µg/ml + Water for Injection
Compatible 100 mg/ml + InjectionFluconazole 2 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionFurosemide 10 mg/ml + Water for Injection
Incompatible 100 mg/ml + InjectionGentamicin sulfate 40 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionHeparin sodium 100 UI/ml + Water for Injection
Incompatible 100 mg/ml + InjectionHydralazine hydrochloride 20 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionHydrocortisone sodium succinate 125 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionHydromorphone hydrochloride 10 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionInsulin 100 UI/ml + Water for Injection
Compatible 100 mg/ml + InjectionIsoprenaline hydrochloride 0.2 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionKetamine hydrochloride 50 mg/ml + Water for Injection
Incompatible 100 mg/ml + InjectionLabetalol hydrochloride 5 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionLevofloxacine 5 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionLidocaine hydrochloride 1 mg/ml + Water for Injection
Incompatible 100 mg/ml + InjectionLorazepam 4 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionMagnesium sulfate 500 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionMannitol 250 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionMeropenem 50 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionMethylprednisolone sodium succinate 62.5 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionMetoclopramide hydrochloride 5 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionMetronidazole 5 mg/ml + Water for Injection
Incompatible 100 mg/ml + InjectionMidazolam hydrochloride 5 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionMilrinone lactate 1 mg/ml + Water for Injection
Incompatible 100 mg/ml + InjectionMorphine sulfate 50 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionN-acetylcysteine 200 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionNaloxone hydrochloride 0.4 mg/ml + Water for Injection
Incompatible 100 mg/ml + InjectionNitroglycerin 5 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionNitroprusside sodium 25 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionNorepinephrine bitartrate 1 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionOndansetron hydrochloride 2 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionOxytocin 10 UI/ml + Water for Injection
Compatible 100 mg/ml + InjectionPantoprazole sodium 4 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionPenicillin G sodium 0.5 MUI/ml + Water for Injection
Incompatible 100 mg/ml + InjectionPhenytoin sodium 50 mg/ml + Water for Injection
Incompatible 100 mg/ml + InjectionPiperacillin sodium 300 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionPiperacillin sodium / tazobactam 225 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionPotassium chloride 200 mEq/l + Water for Injection
Incompatible 100 mg/ml + InjectionPotassium phosphate 3 mmol/ml + Water for Injection
Incompatible 100 mg/ml + InjectionPromethazine hydrochloride 25 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionPropranolol hydrochloride 1 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionRanitidine hydrochloride 25 mg/ml + Water for Injection
Incompatible 100 mg/ml + InjectionRocuronium bromide 10 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionSalbutamol sulfate 1 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionSodium bicarbonate 84 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionSufentanil citrate 0.05 mg/ml + Water for Injection
Incompatible 100 mg/ml + InjectionTicarcillin / clavulanic acid 200/6,7 mg/ml + Water for Injection
Incompatible 100 mg/ml + InjectionTobramycin sulfate 40 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionValproic acid 100 mg/ml + Water for Injection
Incompatible 100 mg/ml + InjectionVancomycin hydrochloride 50 mg/ml + Water for Injection
Compatible 100 mg/ml + InjectionVoriconazole 10 mg/ml + Water for Injection
InjectionCo-trimoxazole Antibiotic
Incompatible 80/16 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 4 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionDiazepam Anxiolytic
Incompatible 5 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionDigoxin Cardiotonic
Compatible 50 µg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionDimenhydrinate Antihistamine (H1)
Compatible 10 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionDiphenhydramine hydrochloride Antihistamine (H1)
Incompatible 50 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionDobutamine hydrochloride Cardiotonic
Incompatible 12,5 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionDopamine hydrochloride Cardiotonic
Compatible 3.2 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionDroperidol Neuroleptic
Incompatible 2,5 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionEpinephrine hydrochloride Sympathomimetic
Compatible 1000 µg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
Compatible 100 µg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionErythromycin lactobionate Antibiotic
Incompatible 50 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionEsmolol hydrochloride Beta-blocker
Compatible 10 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionFentanyl citrate Analgesic
Compatible 50 µg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionFluconazole Antifungal
Compatible 2 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionFurosemide Diuretic
Compatible 10 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionGentamicin sulfate Antibiotic
Incompatible 40 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionHeparin sodium Anticoagulant
Compatible 100 UI/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionHydralazine hydrochloride Antihypertensive
Incompatible 20 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 125 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionHydromorphone hydrochloride Analgesic
Compatible 10 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionInsulin Glucose-lowering
Compatible 100 UI/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionIsoprenaline hydrochloride Beta-stimulant
Compatible 0.2 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionKetamine hydrochloride General anesthetic
Compatible 50 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionLabetalol hydrochloride Beta-blocker
Incompatible 5 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionLevofloxacine Antibiotic
Compatible 5 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionLidocaine hydrochloride Local anesthetic
Compatible 1 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionLorazepam Anxiolytic
Incompatible 4 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionMagnesium sulfate Electrolyte
Compatible 500 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionMannitol Various
Compatible 250 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionMeropenem Antibiotic
Compatible 50 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionMethylprednisolone sodium succinate Anti-inflammatory
Compatible 62.5 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionMetoclopramide hydrochloride Antiemetic
Compatible 5 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionMetronidazole Antiparasitic
Compatible 5 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionMidazolam hydrochloride Anxiolytic
Incompatible 5 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionMilrinone lactate Cardiotonic
Compatible 1 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionMorphine sulfate Analgesic
Incompatible 50 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionN-acetylcysteine Antidote
Compatible 200 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionNaloxone hydrochloride Antidote
Compatible 0.4 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionNitroglycerin Vasodilator
Incompatible 5 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionNitroprusside sodium Vasodilator
Compatible 25 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionNorepinephrine bitartrate Sympathomimetic
Compatible 1 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionOndansetron hydrochloride Antiemetic
Compatible 2 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionOxytocin Various
Compatible 10 UI/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionPantoprazole sodium Proton pump inhibitor
Compatible 4 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionPenicillin G sodium Antibiotic
Compatible 0.5 MUI/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionPhenytoin sodium Antiepileptic
Incompatible 50 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionPiperacillin sodium Antibiotic
Incompatible 300 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionPiperacillin sodium / tazobactam Antibiotic
Compatible 225 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionPotassium chloride Electrolyte
Compatible 200 mEq/l + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionPotassium phosphate Electrolyte
Incompatible 3 mmol/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionPromethazine hydrochloride Antihistamine (H1)
Incompatible 25 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionPropranolol hydrochloride Beta-blocker
Compatible 1 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionRanitidine hydrochloride Antihistamine (H2)
Compatible 25 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionRocuronium bromide Curarimimetic
Incompatible 10 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionSalbutamol sulfate Beta-stimulant
Compatible 1 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionSodium bicarbonate Electrolyte
Compatible 84 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionSufentanil citrate Analgesic
Compatible 0.05 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionTicarcillin / clavulanic acid Antibiotic
Incompatible 200/6,7 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionTobramycin sulfate Antibiotic
Incompatible 40 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionValproic acid Antiepileptic
Compatible 100 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionVancomycin hydrochloride Antibiotic
Incompatible 50 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection
InjectionVoriconazole Antifungal
Compatible 10 mg/ml + InjectionCloxacillin sodium 100 mg/ml + Water for Injection

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