Last update :
16/06/2024
References   References 2109  
Type : Journal
Web link : http://www.pharmactuel.com/index.php/pharmactuel/issue/view/48

Research teams : Montreal - Centre hospitalier Sainte Justine
Authors : Pelletier E, Forest JM, Hildgen P.
Title : Compatibilité de la kétamine injectable lors de l’administration en dérivé avec d’autres médicaments usuels.
Reference : Pharmactuel ; 39: 71-75. 2006

Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Not rated: compatibility study only

List of drugs
InjectionAciclovir sodium Antiviral
Incompatible 50 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionAmikacin sulfate Antibiotic
Compatible 250 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionAminophylline Various
Incompatible 50 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionAmiodarone hydrochloride Anti-arrhythmic
Compatible 50 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionAmpicillin sodium Antibiotic
Incompatible 250 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionAtropine sulfate Antimuscarinic
Compatible 0.4 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionCaffeine Respiratory stimulant
Compatible 10 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionCalcium gluconate Electrolyte
Compatible 100 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionCefazolin sodium Antibiotic
Compatible 100 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionCefotaxime sodium Antibiotic
Compatible 100 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionCeftazidime Antibiotic
Compatible 100 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionCefuroxime sodium Antibiotic
Compatible 100 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionChlorpromazine hydrochloride Anxiolytic
Compatible 25 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionCiclosporin Immunosuppressant
Incompatible 50 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionClindamycin phosphate Antibiotic
Compatible 150 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionCloxacillin sodium Antibiotic
Compatible 100 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionCo-trimoxazole Antibiotic
Incompatible 80/16 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionDexamethasone sodium phosphate Anti-inflammatory
Incompatible 10 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionDigoxin Cardiotonic
Compatible 50 µg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionDimenhydrinate Antihistamine (H1)
Compatible 50 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionDiphenhydramine hydrochloride Antihistamine (H1)
Compatible 50 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionDobutamine hydrochloride Cardiotonic
Compatible 12.5 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionDopamine hydrochloride Cardiotonic
Compatible 40 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionEpinephrine hydrochloride Sympathomimetic
Compatible 1000 µg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionFurosemide Diuretic
Incompatible 10 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionGentamicin sulfate Antibiotic
Compatible 40 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionHeparin sodium Anticoagulant
Incompatible 25000 UI/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 125 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionInsulin Glucose-lowering
Incompatible 100 UI/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionKetamine hydrochloride General anesthetic
Incompatible 50 mg/ml + NaHCO3
Incompatible 50 mg/ml + InjectionAciclovir sodium 50 mg/ml
Compatible 50 mg/ml + InjectionAmikacin sulfate 250 mg/ml
Incompatible 50 mg/ml + InjectionAminophylline 50 mg/ml
Compatible 50 mg/ml + InjectionAmiodarone hydrochloride 50 mg/ml
Incompatible 50 mg/ml + InjectionAmpicillin sodium 250 mg/ml
Compatible 50 mg/ml + InjectionAtropine sulfate 0.4 mg/ml
Compatible 50 mg/ml + InjectionCaffeine 10 mg/ml
Compatible 50 mg/ml + InjectionCalcium gluconate 100 mg/ml
Compatible 50 mg/ml + InjectionCefazolin sodium 100 mg/ml
Compatible 50 mg/ml + InjectionCefotaxime sodium 100 mg/ml
Compatible 50 mg/ml + InjectionCeftazidime 100 mg/ml
Compatible 50 mg/ml + InjectionCefuroxime sodium 100 mg/ml
Compatible 50 mg/ml + InjectionChlorpromazine hydrochloride 25 mg/ml
Incompatible 50 mg/ml + InjectionCiclosporin 50 mg/ml
Compatible 50 mg/ml + InjectionClindamycin phosphate 150 mg/ml
Compatible 50 mg/ml + InjectionCloxacillin sodium 100 mg/ml
Incompatible 50 mg/ml + InjectionCo-trimoxazole 80/16 mg/ml
Incompatible 50 mg/ml + InjectionDexamethasone sodium phosphate 10 mg/ml
Compatible 50 mg/ml + InjectionDigoxin 50 µg/ml
Compatible 50 mg/ml + InjectionDimenhydrinate 50 mg/ml
Compatible 50 mg/ml + InjectionDiphenhydramine hydrochloride 50 mg/ml
Compatible 50 mg/ml + InjectionDobutamine hydrochloride 12.5 mg/ml
Compatible 50 mg/ml + InjectionDopamine hydrochloride 40 mg/ml
Compatible 50 mg/ml + InjectionEpinephrine hydrochloride 1000 µg/ml
Incompatible 50 mg/ml + InjectionFurosemide 10 mg/ml
Compatible 50 mg/ml + InjectionGentamicin sulfate 40 mg/ml
Incompatible 50 mg/ml + InjectionHeparin sodium 25000 UI/ml
Compatible 50 mg/ml + InjectionHydrocortisone sodium succinate 125 mg/ml
Incompatible 50 mg/ml + InjectionInsulin 100 UI/ml
Incompatible 50 mg/ml + InjectionLorazepam 4 mg/ml
Compatible 50 mg/ml + InjectionMagnesium sulfate 500 mg/ml
Incompatible 50 mg/ml + InjectionMeropenem 50 mg/ml
Compatible 50 mg/ml + InjectionMethylprednisolone acetate 62.5 mg/ml
Compatible 50 mg/ml + InjectionMetoclopramide hydrochloride 5 mg/ml
Compatible 50 mg/ml + InjectionMetronidazole 5 mg/ml
Compatible 50 mg/ml + InjectionMidazolam hydrochloride 5 mg/ml
Compatible 50 mg/ml + InjectionMilrinone lactate 1 mg/ml
Compatible 50 mg/ml + InjectionNaloxone hydrochloride 0.4 mg/ml
Incompatible 50 mg/ml + InjectionNitroglycerin 5 mg/ml
Compatible 50 mg/ml + InjectionOxytocin 10 UI/ml
Compatible 50 mg/ml + InjectionPancuronium bromide 2 mg/ml
Compatible 50 mg/ml + InjectionPethidine hydrochloride 100 mg/ml
Incompatible 50 mg/ml + InjectionPhenytoin sodium 50 mg/ml
Incompatible 50 mg/ml + InjectionPiperacillin sodium 200 mg/ml
Compatible 50 mg/ml + InjectionPiperacillin sodium / tazobactam 200 mg/ml
Compatible 50 mg/ml + InjectionPotassium chloride 2000 mEq/l
Incompatible 50 mg/ml + InjectionPotassium phosphate 4 mmol/ml
Compatible 50 mg/ml + InjectionPromethazine hydrochloride 25 mg/ml
Compatible 50 mg/ml + InjectionRanitidine hydrochloride 25 mg/ml
Incompatible 50 mg/ml + InjectionSalbutamol sulfate 1 mg/ml
Incompatible 50 mg/ml + InjectionSodium bicarbonate 84 mg/ml
Compatible 50 mg/ml + InjectionTobramycin sulfate 40 mg/ml
Compatible 50 mg/ml + InjectionVancomycin hydrochloride 50 mg/ml
InjectionLorazepam Anxiolytic
Incompatible 4 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionMagnesium sulfate Electrolyte
Compatible 500 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionMeropenem Antibiotic
Incompatible 50 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionMethylprednisolone acetate Anti-inflammatory
Compatible 62.5 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionMetoclopramide hydrochloride Antiemetic
Compatible 5 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionMetronidazole Antiparasitic
Compatible 5 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionMidazolam hydrochloride Anxiolytic
Compatible 5 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionMilrinone lactate Cardiotonic
Compatible 1 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionNaloxone hydrochloride Antidote
Compatible 0.4 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionNitroglycerin Vasodilator
Incompatible 5 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionOxytocin Various
Compatible 10 UI/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionPancuronium bromide Curarimimetic
Compatible 2 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionPethidine hydrochloride Analgesic
Compatible 100 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionPhenytoin sodium Antiepileptic
Incompatible 50 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionPiperacillin sodium Antibiotic
Incompatible 200 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionPiperacillin sodium / tazobactam Antibiotic
Compatible 200 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionPotassium chloride Electrolyte
Compatible 2000 mEq/l + InjectionKetamine hydrochloride 50 mg/ml
InjectionPotassium phosphate Electrolyte
Incompatible 4 mmol/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionPromethazine hydrochloride Antihistamine (H1)
Compatible 25 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionRanitidine hydrochloride Antihistamine (H2)
Compatible 25 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionSalbutamol sulfate Beta-stimulant
Incompatible 1 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionSodium bicarbonate Electrolyte
Incompatible 84 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionTobramycin sulfate Antibiotic
Compatible 40 mg/ml + InjectionKetamine hydrochloride 50 mg/ml
InjectionVancomycin hydrochloride Antibiotic
Compatible 50 mg/ml + InjectionKetamine hydrochloride 50 mg/ml

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