Last update :
16/06/2024
References   References 3976  
Type : Journal
Web link : https://doi.org/10.2146/ajhp170111
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Research teams : Marseille - La Timone University Teaching Hospital, Pharmacy Department
Authors : Du Repaire T, Vigne P, Guedon A, Gauthier-Villano L, Bertault Peres P, Pourroy B.
Title : Visual compatibility of blinatumomab with selected co-administrated drugs during simulated Y-site administration.
Reference : Am J Health-Syst Pharm ; 74,16 : 1217-1218 2017

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
InjectionAlizapride hydrochloride Antiemetic
Incompatible 0.5 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionAmphotericin B liposomale Antifungal
Compatible 1 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionBlinatumomab Anticancer drug
Incompatible 0.125 & 0.375 µg/ml + InjectionAlizapride hydrochloride 0.5 mg/ml + Sodium chloride 0,9%
Compatible 0.125 & 0.375 µg/ml + InjectionAmphotericin B liposomale 1 mg/ml + Sodium chloride 0,9%
Compatible 0.125 & 0.375 µg/ml + InjectionCaffeine citrate 25 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionCaspofungin acetate 0.20 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionCeftazidime 34.5 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionCeftriaxone disodium 50 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionCiprofloxacin lactate 2 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionClonazepam 0.02 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionCloxacillin sodium 8.6 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionCo-trimoxazole 3.2 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionDaptomycin 6.1 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionDexamethasone sodium phosphate 0.19 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionFurosemide 2.9 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionHeparin sodium 192.3 UI/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionHuman albumin 100 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionHuman albumin 100 mg/ml + Sodium chloride 0,9%
Compatible 0.125 & 0.375 µg/ml + InjectionHydrocortisone sodium succinate 0.98 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionHydroxyzine dihydrochloride 0.4 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionImipenem - cilastatin sodium 5 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionMeropenem 8.3 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionMethylprednisolone sodium succinate 5 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionMetronidazole 2.5 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionMidazolam hydrochloride 1 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionMorphine hydrochloride 1 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionNalbuphine hydrochloride 1 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionNaloxone hydrochloride 0.2 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionNefopam 2.5 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionOmeprazole sodium 0.4 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionOndansetron hydrochloride 0.2 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionPantoprazole sodium 0.8 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionParacetamol 10 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionPhloroglucinol 5 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionPotassium chloride 0.3 mEq/l + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionRasburicase 0.15 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionTeicoplanine 4 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionTranexamic acid 100 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + InjectionVancomycin hydrochloride 2 mg/ml + Sodium chloride 0,9%
Incompatible 0.125 & 0.375 µg/ml + Parenteral nutrition (binary mixture)
InjectionCaffeine citrate Respiratory stimulant
Compatible 25 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionCaspofungin acetate Antifungal
Incompatible 0.20 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionCeftazidime Antibiotic
Incompatible 34.5 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionCeftriaxone disodium Antibiotic
Incompatible 50 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionCiprofloxacin lactate Antibiotic
Incompatible 2 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionClonazepam Antiepileptic
Incompatible 0.02 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionCloxacillin sodium Antibiotic
Incompatible 8.6 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionCo-trimoxazole Antibiotic
Incompatible 3.2 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionDaptomycin Antibiotic
Incompatible 6.1 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionDexamethasone sodium phosphate Anti-inflammatory
Incompatible 0.19 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionFurosemide Diuretic
Incompatible 2.9 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionHeparin sodium Anticoagulant
Incompatible 192.3 UI/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionHuman albumin Various
Incompatible 100 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
Incompatible 100 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 0.98 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionHydroxyzine dihydrochloride Anxiolytic
Incompatible 0.4 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionImipenem - cilastatin sodium Antibiotic
Incompatible 5 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionMeropenem Antibiotic
Incompatible 8.3 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionMethylprednisolone sodium succinate Anti-inflammatory
Incompatible 5 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionMetronidazole Antiparasitic
Incompatible 2.5 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionMidazolam hydrochloride Anxiolytic
Incompatible 1 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionMorphine hydrochloride Analgesic
Incompatible 1 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionNalbuphine hydrochloride Antidote
Incompatible 1 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionNaloxone hydrochloride Antidote
Incompatible 0.2 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionNefopam Analgesic
Incompatible 2.5 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionOmeprazole sodium Proton pump inhibitor
Incompatible 0.4 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionOndansetron hydrochloride Antiemetic
Incompatible 0.2 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionPantoprazole sodium Proton pump inhibitor
Incompatible 0.8 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionParacetamol Analgesic
Incompatible 10 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionPhloroglucinol  Antispasmodic
Incompatible 5 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionPotassium chloride Electrolyte
Incompatible 0.3 mEq/l + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionRasburicase Various
Incompatible 0.15 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionTeicoplanine Antibiotic
Incompatible 4 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionTranexamic acid Anti-bleeding
Incompatible 100 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%
InjectionVancomycin hydrochloride Antibiotic
Incompatible 2 mg/ml + InjectionBlinatumomab 0.125 & 0.375 µg/ml + Sodium chloride 0,9%

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