Last update :
08/05/2024
References   References 2247  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=2783

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Chan P, Heatherly K, Kupiec T.C, Trissel L.A.
Title : Compatibility of caspofungin acetate injection with other drugs during simulated Y-site coadministration.
Reference : Int J Pharm Compound ; 12, 3: 276-278. 2008

Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Not rated: compatibility study only

List of drugs
InjectionAciclovir sodium Antiviral
Compatible 7 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionAmikacin sulfate Antibiotic
Compatible 5 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionAmiodarone hydrochloride Anti-arrhythmic
Compatible 4 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionAmphotericin B Antifungal
Incompatible 0,6 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionAmphotericin B lipid complex Antifungal
Incompatible 1 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionAmphotericin B liposomale Antifungal
Incompatible 1 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionAmpicillin sodium Antibiotic
Incompatible 20 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionAztreonam Antibiotic
Compatible 40 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionBumetanide Diuretic
Compatible 0,04 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionCarboplatin Anticancer drug
Compatible 5 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionCaspofungin acetate Antifungal
Compatible 0,7 mg/ml + InjectionAciclovir sodium 7 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionAmikacin sulfate 5 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionAmiodarone hydrochloride 4 mg/ml + Sodium chloride 0,9%
Incompatible 0,7 mg/ml + InjectionAmphotericin B 0,6 mg/ml + Sodium chloride 0,9%
Incompatible 0,7 mg/ml + InjectionAmphotericin B lipid complex 1 mg/ml + Sodium chloride 0,9%
Incompatible 0,7 mg/ml + InjectionAmphotericin B liposomale 1 mg/ml + Sodium chloride 0,9%
Incompatible 0,7 mg/ml + InjectionAmpicillin sodium 20 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionAztreonam 40 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionBumetanide 0,04 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionCarboplatin 5 mg/ml + Sodium chloride 0,9%
Incompatible 0,7 mg/ml + InjectionCefazolin sodium 20 mg/ml + Sodium chloride 0,9%
Incompatible 0,7 mg/ml + InjectionCefepime dihydrochloride 20 mg/ml + Sodium chloride 0,9%
Incompatible 0,7 mg/ml + InjectionCeftazidime 40 mg/ml + Sodium chloride 0,9%
Incompatible 0,7 mg/ml + InjectionCeftriaxone disodium 20 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionCiclosporin 5 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionCiprofloxacin lactate 2 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionCisplatin 0,5 mg/ml + Sodium chloride 0,9%
Incompatible 0,7 mg/ml + InjectionClindamycin phosphate 10 mg/ml + Sodium chloride 0,9%
Incompatible 0,7 mg/ml + InjectionCo-trimoxazole 4/0,8 mg/ml + Sodium chloride 0,9%
Incompatible 0,7 mg/ml + InjectionCytarabine 50 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionDaptomycin 10 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionDaunorubicin hydrochloride 1 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionDiltiazem hydrochloride 5 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionDobutamine hydrochloride 4 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionDopamine hydrochloride 3,2 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionDoxorubicin hydrochloride 1 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionEpinephrine hydrochloride 0,05 µg/ml + Sodium chloride 0,9%
Incompatible 0,7 mg/ml + InjectionErtapenem 20 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionEtoposide phosphate 5 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionFentanyl citrate 50 µg/ml + Sodium chloride 0,9%
Incompatible 0,7 mg/ml + InjectionFurosemide 3 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionGanciclovir sodium 20 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionGentamicin sulfate 5 mg/ml + Sodium chloride 0,9%
Incompatible 0,7 mg/ml + InjectionHeparin sodium 100 UI/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionHydrocortisone sodium succinate 1 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionHydromorphone hydrochloride 1 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionIfosfamide 20 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionImipenem - cilastatin sodium 5 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionInsulin 1 UI/ml + Sodium chloride 0,9%
Incompatible 0,7 mg/ml + InjectionLansoprazole 0,55 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionLevofloxacine 5 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionLinezolid 2 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionLorazepam 0,5 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionMagnesium sulfate 100 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionMelphalan 1 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionMeropenem 2,5 mg/ml + Sodium chloride 0,9%
Incompatible 0,7 mg/ml + InjectionMethylprednisolone sodium succinate 5 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionMetronidazole 5 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionMidazolam hydrochloride 2 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionMilrinone lactate 0,2 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionMitomycin 0,5 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionMorphine sulfate 15 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionMycophenolate mofetil 6 mg/ml + Sodium chloride 0,9%
Incompatible 0,7 mg/ml + InjectionNafcillin sodium 20 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionNorepinephrine bitartrate 0,128 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionPantoprazole sodium 0,4 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionPhenylephrine hydrochloride 1 mg/ml + Sodium chloride 0,9%
Incompatible 0,7 mg/ml + InjectionPiperacillin sodium / tazobactam 40/5 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionPotassium chloride 100 mEq/l + Sodium chloride 0,9%
Incompatible 0,7 mg/ml + InjectionPotassium phosphate 0,5 mmol/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionQuinupristine/dalfopristine 5 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionTacrolimus 20 µg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionTobramycin sulfate 5 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionVancomycin hydrochloride 10 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionVincristine sulfate 0,05 mg/ml + Sodium chloride 0,9%
Compatible 0,7 mg/ml + InjectionVoriconazole 4 mg/ml + Sodium chloride 0,9%
InjectionCefazolin sodium Antibiotic
Incompatible 20 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionCefepime dihydrochloride Antibiotic
Incompatible 20 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionCeftazidime Antibiotic
Incompatible 40 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionCeftriaxone disodium Antibiotic
Incompatible 20 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionCiclosporin Immunosuppressant
Compatible 5 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionCiprofloxacin lactate Antibiotic
Compatible 2 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionCisplatin Anticancer drug
Compatible 0,5 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionClindamycin phosphate Antibiotic
Incompatible 10 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionCo-trimoxazole Antibiotic
Incompatible 4/0,8 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionCytarabine Anticancer drug
Incompatible 50 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionDaptomycin Antibiotic
Compatible 10 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionDaunorubicin hydrochloride Anticancer drug
Compatible 1 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionDiltiazem hydrochloride Anti-arrhythmic
Compatible 5 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionDobutamine hydrochloride Cardiotonic
Compatible 4 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionDopamine hydrochloride Cardiotonic
Compatible 3,2 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionDoxorubicin hydrochloride Anticancer drug
Compatible 1 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionEpinephrine hydrochloride Sympathomimetic
Compatible 0,05 µg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionErtapenem Antibiotic
Incompatible 20 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionEtoposide phosphate Anticancer drug
Compatible 5 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionFentanyl citrate Analgesic
Compatible 50 µg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionFurosemide Diuretic
Incompatible 3 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionGanciclovir sodium Antiviral
Compatible 20 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionGentamicin sulfate Antibiotic
Compatible 5 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionHeparin sodium Anticoagulant
Incompatible 100 UI/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 1 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionHydromorphone hydrochloride Analgesic
Compatible 1 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionIfosfamide Anticancer drug
Compatible 20 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionImipenem - cilastatin sodium Antibiotic
Compatible 5 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionInsulin Glucose-lowering
Compatible 1 UI/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionLansoprazole Proton pump inhibitor
Incompatible 0,55 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionLevofloxacine Antibiotic
Compatible 5 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionLinezolid Antibiotic
Compatible 2 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionLorazepam Anxiolytic
Compatible 0,5 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionMagnesium sulfate Electrolyte
Compatible 100 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionMelphalan Anticancer drug
Compatible 1 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionMeropenem Antibiotic
Compatible 2,5 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionMethylprednisolone sodium succinate Anti-inflammatory
Incompatible 5 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionMetronidazole Antiparasitic
Compatible 5 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionMidazolam hydrochloride Anxiolytic
Compatible 2 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionMilrinone lactate Cardiotonic
Compatible 0,2 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionMitomycin Anticancer drug
Compatible 0,5 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionMorphine sulfate Analgesic
Compatible 15 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionMycophenolate mofetil Immunosuppressant
Compatible 6 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionNafcillin sodium Antibiotic
Incompatible 20 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionNorepinephrine bitartrate Sympathomimetic
Compatible 0,128 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionPantoprazole sodium Proton pump inhibitor
Compatible 0,4 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionPethidine hydrochloride Analgesic
Compatible 10 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionPhenylephrine hydrochloride Sympathomimetic
Compatible 1 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionPiperacillin sodium / tazobactam Antibiotic
Incompatible 40/5 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionPotassium chloride Electrolyte
Compatible 100 mEq/l + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionPotassium phosphate Electrolyte
Incompatible 0,5 mmol/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionQuinupristine/dalfopristine Antibiotic
Compatible 5 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionTacrolimus Immunosuppressant
Compatible 20 µg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionTobramycin sulfate Antibiotic
Compatible 5 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionVancomycin hydrochloride Antibiotic
Compatible 10 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionVincristine sulfate Anticancer drug
Compatible 0,05 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%
InjectionVoriconazole Antifungal
Compatible 4 mg/ml + InjectionCaspofungin acetate 0,7 mg/ml + Sodium chloride 0,9%

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