Last update :
16/07/2021
References   References 253  
Type : Journal

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Trissel LA, Chandler SW, Folstad JT.
Title : Visual compatibility of amsacrine with selected drugs during simulated Y-site injection.
Reference : Am J Hosp Pharm ; 47: 2525-2528. 1990

Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Not rated: compatibility study only

List of drugs
InjectionAciclovir sodium Antiviral
Incompatible 7 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionAmikacin sulfate Antibiotic
Compatible 5 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionAmphotericin B Antifungal
Incompatible 0.6 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionAmsacrine Anticancer drug
Factors which affect stability Solvent Sodium chloride 0,9% Induces Precipitation
Incompatible + Sodium chloride 0,9%
Incompatible 1 mg/ml + InjectionAciclovir sodium 7 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionAmikacin sulfate 5 mg/ml + Glucose 5%
Incompatible 1 mg/ml + InjectionAmphotericin B 0.6 mg/ml + Glucose 5%
Incompatible 1 mg/ml + InjectionAztreonam 40 mg/ml + Glucose 5%
Incompatible 1 mg/ml + InjectionCeftazidime 40 mg/ml + Glucose 5%
Incompatible 1 mg/ml + InjectionCeftriaxone disodium 40 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionChlorpromazine hydrochloride 2 mg/ml + Glucose 5%
Incompatible 1 mg/ml + InjectionCimetidine hydrochloride 12 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionClindamycin phosphate 10 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionCytarabine 50 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionDexamethasone sodium phosphate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionDiphenhydramine hydrochloride 2 mg/ml + Glucose 5%
Incompatible 1 mg/ml + InjectionFurosemide 3 mg/ml + Glucose 5%
Incompatible 1 mg/ml + InjectionGanciclovir sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionGentamicin sulfate 5 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionHaloperidol lactate 0.2 mg/ml + Glucose 5%
Incompatible 1 mg/ml + InjectionHeparin sodium 40 UI/ml + Glucose 5%
Compatible 1 mg/ml + InjectionHydrocortisone sodium succinate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionHydromorphone hydrochloride 0.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionLorazepam 0.1 mg/ml + Glucose 5%
Incompatible 1 mg/ml + InjectionMethylprednisolone sodium succinate 5 mg/ml + Glucose 5%
Incompatible 1 mg/ml + InjectionMetoclopramide hydrochloride 2.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionProchlorperazine edysilate 0.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionPromethazine hydrochloride 2 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionRanitidine hydrochloride 2 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionTobramycin sulfate 5 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
InjectionAztreonam Antibiotic
Incompatible 40 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionCeftazidime Antibiotic
Incompatible 40 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionCeftriaxone disodium Antibiotic
Incompatible 40 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionChlorpromazine hydrochloride Anxiolytic
Compatible 2 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionCimetidine hydrochloride Antihistamine (H2)
Incompatible 12 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionClindamycin phosphate Antibiotic
Compatible 10 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionCytarabine Anticancer drug
Compatible 50 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 1 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionDiphenhydramine hydrochloride Antihistamine (H1)
Compatible 2 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionFurosemide Diuretic
Incompatible 3 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionGanciclovir sodium Antiviral
Incompatible 20 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionGentamicin sulfate Antibiotic
Compatible 5 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionHaloperidol lactate Neuroleptic
Compatible 0.2 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionHeparin sodium Anticoagulant
Incompatible 40 UI/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 1 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionHydromorphone hydrochloride Analgesic
Compatible 0.5 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionLorazepam Anxiolytic
Compatible 0.1 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionMethylprednisolone sodium succinate Anti-inflammatory
Incompatible 5 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionMetoclopramide hydrochloride Antiemetic
Incompatible 2.5 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionMorphine sulfate Analgesic
Compatible 1 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionProchlorperazine edysilate Neuroleptic
Compatible 0.5 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionPromethazine hydrochloride Antihistamine (H1)
Compatible 2 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionRanitidine hydrochloride Antihistamine (H2)
Compatible 2 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionTobramycin sulfate Antibiotic
Compatible 5 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%
InjectionVancomycin hydrochloride Antibiotic
Compatible 10 mg/ml + InjectionAmsacrine 1 mg/ml + Glucose 5%

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