Last update :
13/11/2024
References   References 253  
Type : Journal

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Trissel LA, Chandler SW, Folstad JT.
Title : Visual compatibility of amsacrine with selected drugs during simulated Y-site injection.
Reference : Am J Hosp Pharm ; 47: 2525-2528. 1990

Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Not rated: compatibility study only

List of drugs
injectionAciclovir sodium Antiviral
Incompatible 7 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionAmikacin sulfate Antibiotic
Compatible 5 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionAmphotericin B Antifungal
Incompatible 0.6 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionAmsacrine Anticancer drug
Factors which affect stability Solvent Sodium chloride 0,9% Induces Precipitation
Incompatible + Sodium chloride 0,9%
Incompatible 1 mg/ml + injectionAciclovir sodium 7 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionAmikacin sulfate 5 mg/ml + Glucose 5%
Incompatible 1 mg/ml + injectionAmphotericin B 0.6 mg/ml + Glucose 5%
Incompatible 1 mg/ml + injectionAztreonam 40 mg/ml + Glucose 5%
Incompatible 1 mg/ml + injectionCeftazidime 40 mg/ml + Glucose 5%
Incompatible 1 mg/ml + injectionCeftriaxone disodium 40 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionChlorpromazine hydrochloride 2 mg/ml + Glucose 5%
Incompatible 1 mg/ml + injectionCimetidine hydrochloride 12 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionClindamycin phosphate 10 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionCytarabine 50 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionDexamethasone sodium phosphate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionDiphenhydramine hydrochloride 2 mg/ml + Glucose 5%
Incompatible 1 mg/ml + injectionFurosemide 3 mg/ml + Glucose 5%
Incompatible 1 mg/ml + injectionGanciclovir sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionGentamicin sulfate 5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionHaloperidol lactate 0.2 mg/ml + Glucose 5%
Incompatible 1 mg/ml + injectionHeparin sodium 40 UI/ml + Glucose 5%
Compatible 1 mg/ml + injectionHydrocortisone sodium succinate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionHydromorphone hydrochloride 0.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionLorazepam 0.1 mg/ml + Glucose 5%
Incompatible 1 mg/ml + injectionMethylprednisolone sodium succinate 5 mg/ml + Glucose 5%
Incompatible 1 mg/ml + injectionMetoclopramide hydrochloride 2.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionProchlorperazine edysilate 0.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionPromethazine hydrochloride 2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionRanitidine hydrochloride 2 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionTobramycin sulfate 5 mg/ml + Glucose 5%
Compatible 1 mg/ml + injectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
injectionAztreonam Antibiotic
Incompatible 40 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionCeftazidime Antibiotic
Incompatible 40 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionCeftriaxone disodium Antibiotic
Incompatible 40 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionChlorpromazine hydrochloride Anxiolytic
Compatible 2 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionCimetidine hydrochloride Antihistamine (H2)
Incompatible 12 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionClindamycin phosphate Antibiotic
Compatible 10 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionCytarabine Anticancer drug
Compatible 50 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 1 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionDiphenhydramine hydrochloride Antihistamine (H1)
Compatible 2 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionFurosemide Diuretic
Incompatible 3 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionGanciclovir sodium Antiviral
Incompatible 20 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionGentamicin sulfate Antibiotic
Compatible 5 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionHaloperidol lactate Neuroleptic
Compatible 0.2 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionHeparin sodium Anticoagulant
Incompatible 40 UI/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 1 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionHydromorphone hydrochloride Analgesic
Compatible 0.5 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionLorazepam Anxiolytic
Compatible 0.1 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionMethylprednisolone sodium succinate Anti-inflammatory
Incompatible 5 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionMetoclopramide hydrochloride Antiemetic
Incompatible 2.5 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionMorphine sulfate Analgesic
Compatible 1 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionProchlorperazine edysilate Neuroleptic
Compatible 0.5 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionPromethazine hydrochloride Antihistamine (H1)
Compatible 2 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionRanitidine hydrochloride Antihistamine (H2)
Compatible 2 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionTobramycin sulfate Antibiotic
Compatible 5 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%
injectionVancomycin hydrochloride Antibiotic
Compatible 10 mg/ml + injectionAmsacrine 1 mg/ml + Glucose 5%

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