Last update :
16/06/2024
Beta-blocker   Labetalol hydrochloride  
Injection
Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Albetol Finland
Biascor Argentina, Chile, Ecuador, Peru
Blocamine Argentina
Cebalol India
Deltalol Colombia
Evabet India
Gravidol India
Labesol India
Labeta India
Labetalol Argentina, Canada, United States of America
Labetalol chlorhidrato Chile, Ecuador
Labil India
Trandate Austria, Belgium, Chile, Colombia, Denmark, Finland, France, Germany, Great Britain, Hungary, Iceland, Ireland, Italy, Japan, Luxembourg, Malaysia, Netherlands, New Zealand, Norway, Poland, Saudi Arabia, Spain, Sweden, Switzerland, United Arab Emirates, United States of America
Zeverotens Chile
Compatibility   Injection   Compatibility : Labetalol hydrochloride              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Amikacin sulfate 5 mg/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Aminophylline 1 mg/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 4 mg/ml
Injection Amiodarone hydrochloride 15 mg/ml
NaCl 0,9% or Glucose 5% 3823
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Amiodarone hydrochloride 6 mg/ml
Glucose 5% 1611
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Amiodarone hydrochloride 4.8 mg/ml
Glucose 5% 295
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Amoxicillin sodium / clavulanic acid 100/10 mg/ml
3824
Immediate precipitation Incompatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Amphotericin B cholesteryl sulfate complex 0.83 mg/ml
Glucose 5% 921
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Ampicillin sodium 10 mg/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Atosiban 0,75 mg/ml
4642
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Bivalirudin
3539
Unspecified incompatibility Incompatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Bivalirudin
3539
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Bivalirudin 5 mg/ml
Glucose 5% 1713
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Butorphanol tartrate 0.04 mg/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Caffeine 10 mg/ml
None 3964
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Calcium gluconate 49.5 mg/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Cefazolin sodium 10 mg/ml
Glucose 5% 386
Immediate precipitation Incompatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Cefepime dihydrochloride 40 mg/ml
Sodium chloride 0,9% 3879
Immediate precipitation Incompatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Cefiderocol sulfate tosylate 20 mg/mL
NaCl 0,9% or Glucose 5% 4528
Immediate precipitation Incompatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Cefoperazone sodium 10 mg/ml
Glucose 5% 386
Immediate turbidity Incompatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Ceftaroline fosamil 2,22 mg/ml
NaCl 0,9% or Glucose 5% 3249
Immediate turbidity Incompatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Ceftaroline fosamil 2,22 mg/ml
Ringer’s lactate solution 3249
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Ceftazidime 10 mg/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Ceftizoxime sodium 10 mg/ml
Glucose 5% 386
Immediate precipitation Incompatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Ceftobiprole medocaril sodium 2 mg/ml
NaCl 0,9% or Glucose 5% 2269
Immediate precipitation Incompatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Ceftobiprole medocaril sodium 2 mg/ml
Ringer’s lactate solution 2269
Unspecified incompatibility Incompatible
Injection Labetalol hydrochloride
Injection Ceftobiprole medocaril sodium
4650
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Ceftolozane / tazobactam 10/5 mg/ml
NaCl 0,9% or Glucose 5% 3828
Immediate precipitation Incompatible
Injection Labetalol hydrochloride 5 & 2,5 mg/ml
Injection Ceftriaxone disodium 100 mg/ml
Water for Injection 241
Immediate precipitation Incompatible
Injection Labetalol hydrochloride 5 & 2,5 mg/ml
Injection Ceftriaxone disodium 20 mg/ml
NaCl 0,9% or Glucose 5% 241
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Chloramphenicol sodium succinate 10 mg/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Cimetidine hydrochloride 3 mg/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Ciprofloxacin lactate 2 mg/ml
Sodium chloride 0,9% 3879
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Cisatracurium besylate 2 mg/ml
Sodium chloride 0,9% 3879
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Clindamycin phosphate 9 mg/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Clonidine hydrochloride 0,018 mg/ml
Sodium chloride 0,9% 2018
Immediate precipitation Incompatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Cloxacillin sodium 100 mg/ml
Water for Injection 3012
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Co-trimoxazole 4/0.8 mg/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Dexmedetomidine 4 µg/ml
Sodium chloride 0,9% 1712
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Diltiazem hydrochloride 1 mg/ml
314
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Dobutamine hydrochloride 4 mg/ml
314
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Dobutamine hydrochloride 2.5 mg/ml
Glucose 5% 199
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Dobutamine hydrochloride 4 mg/ml
Glucose 5% 295
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Dopamine hydrochloride 3.2 mg/ml
314
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Dopamine hydrochloride 1.6 mg/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Dopamine hydrochloride 1.6 mg/ml
Glucose 5% 199
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Doripenem 5 mg/ml
NaCl 0,9% or Glucose 5% 2262
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Doripenem 4.5 mg/ml
Sodium chloride 0,9% 3879
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Enalaprilate 0.05 mg/ml
Sodium chloride 0,9% 1315
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Epinephrine hydrochloride 20 µg/ml
314
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Epinephrine hydrochloride 128 µg/ml
Sodium chloride 0,9% 3879
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Erythromycin lactobionate 5 mg/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Esmolol hydrochloride 40 mg/ml
Glucose 5% 295
Compatible
Injection Labetalol hydrochloride 4 mg/ml
Injection Esmolol hydrochloride 10 mg/ml
Sodium chloride 0,9% 3823
Color change Incompatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Esomeprazole sodium 0,8 mg/ml
Sodium chloride 0,9% 3879
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Famotidine 0.2 mg/ml
Glucose 5% 398
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Fentanyl citrate 50 µg/ml
314
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Fentanyl citrate 10 µg/ml
Glucose 5% 386
Turbidity in 15 minutes Incompatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Fosfomycin 30 mg/ml
NaCl 0,9% or Glucose 5% 4055
Immediate precipitation Incompatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Furosemide 10 mg/ml
314
Immediate precipitation Incompatible
Injection Labetalol hydrochloride 1.6 mg/ml
Injection Furosemide 10 mg/ml
Glucose 5% 89
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Gentamicin sulfate 0.8 mg/ml
Glucose 5% 386
Unspecified incompatibility Incompatible
Injection Labetalol hydrochloride 4 mg/ml
Injection Heparin sodium 500 UI/ml
Sodium chloride 0,9% 3823
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Heparin sodium 40 UI/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Ringer’s lactate solution 4603
Immediate precipitation Incompatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Furosemide 10 mg/ml
None 3210
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Heparin sodium 100 UI/ml
314
Unspecified incompatibility Incompatible
Injection Labetalol hydrochloride
Injection Heparin sodium
3540
Unspecified incompatibility Incompatible
Injection Labetalol hydrochloride
NaHCO3 1380
Unspecified incompatibility Incompatible
Injection Labetalol hydrochloride
NaHCO3 3609
Precipitation after 6 hours Incompatible
Injection Labetalol hydrochloride 1,25 >> 3,75 mg/ml
NaHCO3 1194
Immediate precipitation Incompatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Heparin sodium 100 UI/ml
Glucose 5% 295
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Hetastarch 60 mg/ml
Specific solvent 1721
Immediate turbidity Incompatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Human albumin 250 mg/ml
Sodium chloride 0,9% 3879
Immediate turbidity Incompatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Hydrocortisone sodium succinate 1 mg/ml
Sodium chloride 0,9% 3879
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Hydromorphone hydrochloride 1 mg/ml
314
Immediate turbidity Incompatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Ibuprofen lysinate 4 mg/ml
Sodium chloride 0,9% 3879
Modification of pH > 1 pH unit Incompatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Imipenem-Cilastatin / Relebactam 5 mg/ml
NaCl 0,9% or Glucose 5% 4433
Immediate precipitation Incompatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Insulin 1 UI/ml
Glucose 5% 295
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Insulin aspart 1 UI/ml
NaCl 0,9% or Glucose 5% 1508
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Isavuconazonium sulfate 1.5 mg/ml
NaCl 0,9% or Glucose 5% 3829
Immediate precipitation Incompatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Lansoprazole 0.55 mg/ml
Sodium chloride 0,9% 1625
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Levofloxacine 5 mg/ml
Sodium chloride 0,9% 3879
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Levothyroxine 0.4 µg/ml
Sodium chloride 0,9% 3879
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Lidocaine hydrochloride 20 mg/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Linezolid 2 mg/ml
None 1925
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Lorazepam 0.5 mg/ml
314
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Magnesium sulfate 10 mg/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Meropenem 20 mg/ml
Sodium chloride 0,9% 3879
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Meropenem 50 mg/ml
Water for Injection 4319
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Metronidazole 5 mg/ml
Glucose 5% 386
Immediate precipitation Incompatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Micafungin 1.5 mg/ml
Sodium chloride 0,9% 2108
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Midazolam hydrochloride 1 mg/ml
Glucose 5% 295
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Midazolam hydrochloride 2 mg/ml
314
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Milrinone lactate 0.2 mg/ml
314
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Morphine sulfate 0.5 mg/ml
Glucose 5% 199
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Morphine sulfate 1 mg/ml
Glucose 5% 62
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Morphine sulfate 1 mg/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Morphine sulfate 2 mg/ml
314
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection N-acetylcysteine 200 mg/ml
None 3766
Immediate precipitation Incompatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Nafcillin sodium 10 mg/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Naloxone hydrochloride 0.4 mg/ml
None 3408
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Nicardipine hydrochloride 1 mg/ml
314
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Nicardipine hydrochloride 0.1 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Nitroglycerin 0.2 mg/ml
Glucose 5% 295
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Nitroglycerin 0.4 mg/ml
314
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Nitroglycerin 0.2 mg/ml
Glucose 5% 199
Compatible
Injection Labetalol hydrochloride 4 mg/ml
Injection Nitroglycerin 0.2 mg/ml
NaCl 0,9% or Glucose 5% 3823
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Nitroprusside sodium 0.2 mg/ml
Glucose 5% 295
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Norepinephrine bitartrate 0.128 mg/ml
314
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Norepinephrine bitartrate 0.128 mg/ml
Sodium chloride 0,9% 3879
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Norepinephrine bitartrate 0.064 mg/ml
Glucose 5% 295
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Oxacillin sodium 10 mg/ml
Glucose 5% 386
Immediate precipitation Incompatible
Injection Labetalol hydrochloride
Injection Pantoprazole sodium
2090
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Paracetamol 10 mg/ml
4742
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Paracetamol 10 mg/ml
Sodium chloride 0,9% 3879
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Penicillin G potassium 0.05 MUI/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Pethidine hydrochloride 10 mg/ml
Glucose 5% 62
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Piperacillin sodium 10 mg/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Plazomicin sulfate 24 mg/ml
Sodium chloride 0,9% 4145
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Potassium chloride 400 mEq/l
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Potassium phosphate 0.44 mmol/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Propofol 10 mg/ml
None 300
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Ranitidine hydrochloride 0.5 mg/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Ranitidine hydrochloride 0.6 mg/ml
Glucose 5% 199
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Ranitidine hydrochloride 1 mg/ml
314
Precipitation after 6 hours Incompatible
Injection Labetalol hydrochloride 1,25 >> 3,75 mg/ml
Injection Sodium bicarbonate 50 mg/ml
None 1194
Unspecified incompatibility Incompatible
Injection Labetalol hydrochloride
Injection Sodium bicarbonate
1380
Unspecified incompatibility Incompatible
Injection Labetalol hydrochloride
Injection Sodium bicarbonate
3609
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Sulbactam/durlobactam 15/15 mg/ml
Sodium chloride 0,9% 4801
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Tedizolid phosphate 0.8 mg/ml
Sodium chloride 0,9% 3827
Unspecified incompatibility Incompatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Telavancin hydrochloride 7.5 mg/ml
Ringer’s lactate solution 3254
Compatible
Injection Labetalol hydrochloride 5 mg/ml
Injection Telavancin hydrochloride 7.5 mg/ml
NaCl 0,9% or Glucose 5% 3254
Immediate precipitation Incompatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Thiopental sodium 25 mg/ml
314
Compatible
Injection Labetalol hydrochloride 4 mg/ml
Injection Tirofiban 250 µg/ml
Sodium chloride 0,9% 3823
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Tobramycin sulfate 0.8 mg/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 4 mg/ml
Injection Urapidil 5 mg/ml
Sodium chloride 0,9% 3823
Compatible
Injection Labetalol hydrochloride 1 mg/ml
Injection Vancomycin hydrochloride 5 mg/ml
Glucose 5% 386
Compatible
Injection Labetalol hydrochloride 2 mg/ml
Injection Vecuronium bromide 1 mg/ml
314
Immediate turbidity Incompatible
Injection Labetalol hydrochloride 0.8 mg/ml
Injection Warfarin sodium 2 mg/ml
Glucose 5% 315

  Mentions Légales