Last update :
08/05/2024
Proton pump inhibitor   Pantoprazole sodium  
Injection
Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Acinil Peru
Anagastra Spain
Anetrum Argentina
Belpan India
Controloc Croatia, Egypt, Greece, Hungary, Malaysia, Poland, Romania, Slovenia
Dazol India
Dole India
Ducopan India
Dunapan India
Emzole India
Epant India
Eracid India
Eupantol France
Flumetax Peru
Gastrazol
Inipomp France
Pangest Saudi Arabia
Panto Canada
Pantoc Portugal
Pantoloc Austria, Denmark, Sweden
Pantoprazol Chile, Germany
Pantorc Italy
Pantozol Belgium, Germany, Saudi Arabia, Switzerland
Pantpas Turkey
Protium Great Britain
Protonix United States of America
Segregam Colombia
Somac Australia, Finland, Norway
Zurcal Colombia, Switzerland
Zurcazol Greece
Compatibility   Injection   Compatibility : Pantoprazole sodium              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Color change Incompatible
Injection Pantoprazole sodium 0.8 mg/ml
Parenteral nutrition (binary mixture) 3948
Compatible
Injection Pantoprazole sodium
Injection Acetazolamide
2090
Color change Incompatible
Injection Pantoprazole sodium 8 mg/ml
Injection Acetylsalicylic acid lysinate 8.33 mg/ml
2139
Precipitation after 4 hours Incompatible
Injection Pantoprazole sodium
Injection Aciclovir sodium
2090
Compatible
Injection Pantoprazole sodium
Injection Alprostadil
2090
Color change Incompatible
Injection Pantoprazole sodium 0,8 mg/ml
Parenteral nutrition (with lipids) 3948
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Amikacin sulfate
2090
Compatible
Injection Pantoprazole sodium
Injection Aminophylline
2090
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Amiodarone hydrochloride
2090
Compatible
Injection Pantoprazole sodium 4 mg/ml
Injection Amoxicillin sodium / clavulanic acid 100/10 mg/ml
3824
Turbidity in one hour Incompatible
Injection Pantoprazole sodium
Injection Amphotericin B
2090
Compatible
Injection Pantoprazole sodium 0.16 >> 0.8 mg/ml
Injection Ampicillin sodium 10 >> 40 mg/ml
Sodium chloride 0,9% 1902
Compatible
Injection Pantoprazole sodium
Injection Ampicillin sodium
2090
Compatible
Injection Pantoprazole sodium 0.4 mg/ml
Injection Anidulafungin 0.5 mg/ml
Glucose 5% 1982
Unspecified incompatibility Incompatible
Injection Pantoprazole sodium
Injection Atropine sulfate
2090
Immediate precipitation Incompatible
Injection Pantoprazole sodium 0.8 mg/ml
Injection Blinatumomab 0.125 & 0.375 µg/ml
Sodium chloride 0,9% 3976
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Bretylium tosilate
2090
Compatible
Injection Pantoprazole sodium 40 mg/ml
Injection Caffeine 10 mg/ml
None 3964
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Caffeine
2090
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Calcium chloride
2090
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Calcium gluconate
2090
Compatible
Injection Pantoprazole sodium 0,4 mg/ml
Injection Caspofungin acetate 0,7 mg/ml
Sodium chloride 0,9% 2247
Immediate precipitation Incompatible
Injection Pantoprazole sodium 0.4 mg/ml
Injection Caspofungin acetate 0.5 mg/ml
Sodium chloride 0,9% 2233
Compatible
Injection Pantoprazole sodium 0.16 >> 0.8 mg/ml
Injection Cefazolin sodium 20 >> 40 mg/ml
Sodium chloride 0,9% 1902
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Cefazolin sodium
2090
Compatible
Injection Pantoprazole sodium 4 mg/ml
Injection Cefazolin sodium 41.6 mg/ml
NaCl 0,9% or Glucose 5% 4254
Compatible
Injection Pantoprazole sodium 0.4 mg/ml
Injection Cefiderocol sulfate tosylate 20 mg/mL
NaCl 0,9% or Glucose 5% 4528
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Cefotaxime sodium
2090
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Cefoxitin sodium
2090
Compatible
Injection Pantoprazole sodium 0,4 mg/ml
Injection Ceftaroline fosamil 2,22 mg/ml
Ringer’s lactate solution 3249
Compatible
Injection Pantoprazole sodium 0,4 mg/ml
Injection Ceftaroline fosamil 2,22 mg/ml
NaCl 0,9% or Glucose 5% 3249
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Ceftazidime
2090
Immediate turbidity Incompatible
Injection Pantoprazole sodium 0.4 mg/ml
Injection Ceftobiprole medocaril sodium 2 mg/ml
Ringer’s lactate solution 2269
Unspecified incompatibility Incompatible
Injection Pantoprazole sodium
Injection Ceftobiprole medocaril sodium
4650
Compatible
Injection Pantoprazole sodium 0.4 mg/ml
Injection Ceftobiprole medocaril sodium 2 mg/ml
Glucose 5% 2269
Precipitation after 4 hours Incompatible
Injection Pantoprazole sodium 0.4 mg/ml
Injection Ceftobiprole medocaril sodium 2 mg/ml
Sodium chloride 0,9% 2269
Compatible
Injection Pantoprazole sodium 0.4 mg/ml
Injection Ceftolozane / tazobactam 10/5 mg/ml
NaCl 0,9% or Glucose 5% 3828
Compatible
Injection Pantoprazole sodium 0.16 >> 0.8 mg/ml
Injection Ceftriaxone disodium 20 >> 40 mg/ml
Sodium chloride 0,9% 1902
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Cefuroxime sodium
2090
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Chlorpromazine hydrochloride
2090
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Ciclosporin
2090
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Ciprofloxacin lactate
2090
Turbidity in one hour Incompatible
Injection Pantoprazole sodium 0,8 mg/ml
Injection Cisatracurium besylate 1 mg/ml
Sodium chloride 0,9% 3429
Precipitation after 1 hour Incompatible
Injection Pantoprazole sodium
Injection Clindamycin phosphate
2090
Compatible
Injection Pantoprazole sodium 0.32 mg/ml
Injection Clonidine hydrochloride 0.0075 mg/ml
NaCl 0,9% or Glucose 5% 1506
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Cloxacillin sodium
2090
Compatible
Injection Pantoprazole sodium 4 mg/ml
Injection Cloxacillin sodium 100 mg/ml
Water for Injection 3012
Precipitation after 1 hour Incompatible
Injection Pantoprazole sodium
Injection Co-trimoxazole
2090
Immediate turbidity Incompatible
Injection Pantoprazole sodium 8 mg/ml
Injection Cyamemazin 0.2 mg/ml
2139
Compatible
Injection Pantoprazole sodium
Injection Daunorubicin/cytarabine liposomale 0,4 mg/mL
Sodium chloride 0,9% 4654
Compatible
Injection Pantoprazole sodium 1.6 mg/ml
Injection Defibrotide 8 mg/ml
Sodium chloride 0,9% 3728
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Dexamethasone sodium phosphate
2090
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Diazepam
2090
Precipitation after 4 hours Incompatible
Injection Pantoprazole sodium
Injection Digoxin
2090
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Dimenhydrinate
2090
Compatible
Injection Pantoprazole sodium 0.16 >> 0.8 mg/ml
Injection Dimenhydrinate 0.5 >> 1 mg/ml
Sodium chloride 0,9% 1902
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Diphenhydramine hydrochloride
2090
Compatible
Injection Pantoprazole sodium < 0.05 mg/ml
Injection Dobutamine hydrochloride < 4 mg/ml
Sodium chloride 0,9% 1902
Precipitation after 1 hour Incompatible
Injection Pantoprazole sodium
Injection Dobutamine hydrochloride
2090
Precipitation after 15 minutes Incompatible
Injection Pantoprazole sodium 0,16 >> 0,8 mg/ml
Injection Dobutamine hydrochloride 1 >> 4 mg/ml
Sodium chloride 0,9% 1902
Precipitation after 1 hour Incompatible
Injection Pantoprazole sodium
Injection Dopamine hydrochloride
2090
Compatible
Injection Pantoprazole sodium 0.16 >> 0.8 mg/ml
Injection Dopamine hydrochloride 0.8 >> 3.2 mg/ml
Sodium chloride 0,9% 1902
Compatible
Injection Pantoprazole sodium 0,4 mg/ml
Injection Doripenem 5 mg/ml
NaCl 0,9% or Glucose 5% 2262
Precipitation after 1 hour Incompatible
Injection Pantoprazole sodium
Injection Enalaprilate
2090
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Epinephrine hydrochloride
2090
Compatible
Injection Pantoprazole sodium 0.16 >> 0.8 mg/ml
Injection Epinephrine hydrochloride 16 >> 32 µg/ml
Sodium chloride 0,9% 1902
Compatible
Injection Pantoprazole sodium 0,4 mg/ml
Injection Eravacycline 0,6 mg/ml
Sodium chloride 0,9% 4434
Color change Incompatible
Injection Pantoprazole sodium < 0.12 mg/ml
Injection Esmolol hydrochloride < 2 mg/ml
Sodium chloride 0,9% 1902
Immediate precipitation Incompatible
Injection Pantoprazole sodium > 0.12 mg/ml
Injection Esmolol hydrochloride > 2 mg/ml
Sodium chloride 0,9% 1902
Precipitation after 15 minutes Incompatible
Injection Pantoprazole sodium
Injection Fentanyl citrate
2090
Precipitation after 4 hours Incompatible
Injection Pantoprazole sodium
Injection Fluconazole
2090
Precipitation after 15 minutes Incompatible
Injection Pantoprazole sodium
Injection Furosemide
2090
Precipitation after 15 minutes Incompatible
Injection Pantoprazole sodium
Injection Hydrocortisone sodium succinate
2090
Precipitation after 1 hour Incompatible
Injection Pantoprazole sodium
NaHCO3 2090
Compatible
Injection Pantoprazole sodium 0.32 mg/ml
Injection Fentanyl citrate 30 µg/ml
NaCl 0,9% or Glucose 5% 1506
Compatible
Injection Pantoprazole sodium 0.4 mg/ml
Injection Fosfomycin 30 mg/ml
NaCl 0,9% or Glucose 5% 4055
Compatible
Injection Pantoprazole sodium 0.16 >> 0.8 mg/ml
Injection Furosemide 1 >> 2 mg/ml
Sodium chloride 0,9% 1902
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Gentamicin sulfate
2090
Precipitation after 1 hour Incompatible
Injection Pantoprazole sodium
Injection Heparin sodium
2090
Precipitation after 4 hours Incompatible
Injection Pantoprazole sodium
Injection Hydralazine hydrochloride
2090
Precipitation after 4 hours Incompatible
Injection Pantoprazole sodium
Injection Hydromorphone hydrochloride
2090
Compatible
Injection Pantoprazole sodium 4 mg/ml
Injection Imipenem-Cilastatin / Relebactam 5 mg/ml
NaCl 0,9% or Glucose 5% 4433
Precipitation after 1 hour Incompatible
Injection Pantoprazole sodium
Injection Indomethacin sodium trihydrate
2090
Precipitation after 1 hour Incompatible
Injection Pantoprazole sodium
Injection Insulin
2090
Immediate turbidity Incompatible
Injection Pantoprazole sodium 1 mg/ml
Injection Insulin 1 UI/ml
Sodium chloride 0,9% 4698
Compatible
Injection Pantoprazole sodium 0.16 >> 0.8 mg/ml
Injection Insulin 5 >> 50 UI/ml
Sodium chloride 0,9% 1902
Unspecified incompatibility Incompatible
Injection Pantoprazole sodium 4 mg/ml
Injection Insulin aspart 1 UI/ml
NaCl 0,9% or Glucose 5% 1508
Turbidity in one hour Incompatible
Injection Pantoprazole sodium 0.4 mg/ml
Injection Isavuconazonium sulfate 1.5 mg/ml
NaCl 0,9% or Glucose 5% 3829
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Isoprenaline hydrochloride
2090
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Labetalol hydrochloride
2090
Precipitation after 4 hours Incompatible
Injection Pantoprazole sodium
Injection Lidocaine hydrochloride
2090
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Lorazepam
2090
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Magnesium sulfate
2090
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Mannitol
2090
Compatible
Injection Pantoprazole sodium 4 mg/ml
Injection Meropenem 50 mg/ml
Water for Injection 4319
Precipitation after 15 minutes Incompatible
Injection Pantoprazole sodium
Injection Meropenem
2090
Compatible
Injection Pantoprazole sodium 0.32 mg/ml
Injection Methadone hydrochloride 0.2 mg/ml
NaCl 0,9% or Glucose 5% 1506
Precipitation after 15 minutes Incompatible
Injection Pantoprazole sodium
Injection Metoclopramide hydrochloride
2090
Precipitation after 15 minutes Incompatible
Injection Pantoprazole sodium
Injection Metronidazole
2090
Color change Incompatible
Injection Pantoprazole sodium > 0.01 mg/ml
Injection Midazolam hydrochloride > 0.1 mg/ml
Sodium chloride 0,9% 1902
Compatible
Injection Pantoprazole sodium < 0.01 mg/ml
Injection Midazolam hydrochloride < 0.1 mg/ml
Sodium chloride 0,9% 1902
Color change Incompatible
Injection Pantoprazole sodium 8 mg/ml
Injection Midazolam hydrochloride 0.1 mg/ml
2139
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Midazolam hydrochloride
2090
Immediate precipitation Incompatible
Injection Pantoprazole sodium 4 mg/ml
Injection Naloxone hydrochloride 0.4 mg/ml
None 3408
Precipitation after 4 hours Incompatible
Injection Pantoprazole sodium
Injection Naloxone hydrochloride
2090
Compatible
Injection Pantoprazole sodium 0.04 mg/ml
Injection Nefopam 0.08 mg/ml
2311
Compatible
Injection Pantoprazole sodium 0.16 >> 0.8 mg/ml
Injection Nitroglycerin 0.1 >> 0.4 mg/ml
Sodium chloride 0,9% 1902
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Nitroglycerin
2090
Precipitation after 15 minutes Incompatible
Injection Pantoprazole sodium
Injection Nitroprusside sodium
2090
Compatible
Injection Pantoprazole sodium < 0.8 mg/ml
Injection Norepinephrine bitartrate < 0.013 mg/ml
Sodium chloride 0,9% 1902
Immediate turbidity Incompatible
Injection Pantoprazole sodium > 0.8 mg/ml
Injection Norepinephrine bitartrate > 0.064 mg/ml
Sodium chloride 0,9% 1902
Compatible
Injection Pantoprazole sodium < 0.1 mg/ml
Injection Norepinephrine bitartrate < 0.064 mg/ml
Sodium chloride 0,9% 1902
Precipitation after 15 minutes Incompatible
Injection Pantoprazole sodium
Injection Norepinephrine bitartrate
2090
Compatible
Injection Pantoprazole sodium > 0.5 mg/ml
Injection Octreotide acetate < 0.004 mg/ml
Sodium chloride 0,9% 1902
Color change Incompatible
Injection Pantoprazole sodium > 0.5 mg/ml
Injection Octreotide acetate > 0.004 mg/ml
Sodium chloride 0,9% 1902
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Octreotide acetate
2090
Compatible
Injection Pantoprazole sodium < 0.8 mg/ml
Injection Octreotide acetate < 0.0015 mg/ml
Sodium chloride 0,9% 1902
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Oxytocin
2090
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Pancuronium bromide
2090
Color change Incompatible
Injection Pantoprazole sodium 4 mg/ml
Injection Paracetamol 10 mg/ml
Sodium chloride 0,9% 4698
Compatible
Injection Pantoprazole sodium 4 mg/ml
Injection Paracetamol 10 mg/ml
4742
Compatible
Injection Pantoprazole sodium
Injection Penicillin G sodium
2090
Precipitation after 15 minutes Incompatible
Injection Pantoprazole sodium
Injection Pethidine hydrochloride
2090
Precipitation after 4 hours Incompatible
Injection Pantoprazole sodium
Injection Phenobarbital sodium
2090
Precipitation after 1 hour Incompatible
Injection Pantoprazole sodium
Injection Phenytoin sodium
2090
Precipitation after 1 hour Incompatible
Injection Pantoprazole sodium 4 mg/ml
Injection Phloroglucinol 0,4 mg/ml
Sodium chloride 0,9% 4698
Compatible
Injection Pantoprazole sodium 0,4 mg/ml
Injection Phloroglucinol 2,5 mg/ml
3791
Immediate turbidity Incompatible
Injection Pantoprazole sodium 4 mg/ml
Injection Phytomenadione 0,2 mg/ml
Sodium chloride 0,9% 4698
Compatible
Injection Pantoprazole sodium
Injection Piperacillin sodium
2090
Precipitation after 1 hour Incompatible
Injection Pantoprazole sodium
Injection Piperacillin sodium / tazobactam
2090
Compatible
Injection Pantoprazole sodium 0.4 mg/ml
Injection Plazomicin sulfate 24 mg/ml
Sodium chloride 0,9% 4145
Immediate precipitation Incompatible
Injection Pantoprazole sodium 0,4 mg/ml
Injection Posaconazole 1,2 mg/ml
Sodium chloride 0,9% 4521
Compatible
Injection Pantoprazole sodium
Injection Potassium chloride
2090
Immediate turbidity Incompatible
Injection Pantoprazole sodium 0,4 mg/ml
Normosol® 4655
Compatible
Injection Pantoprazole sodium 0.16 >> 0.8 mg/ml
Injection Potassium chloride 20 >> 4000 mEq/l
Sodium chloride 0,9% 1902
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Potassium phosphate
2090
Compatible
Injection Pantoprazole sodium
Injection Procainamide hydrochloride
2090
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Prochlorperazine edysilate
2090
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Propranolol hydrochloride
2090
Turbidity in one hour Incompatible
Injection Pantoprazole sodium 4 mg/ml
Injection Pyridoxine hydrochloride 0,0025 mg/ml
Sodium chloride 0,9% 4698
Precipitation after 4 hours Incompatible
Injection Pantoprazole sodium
Injection Ranitidine hydrochloride
2090
Compatible
Injection Pantoprazole sodium 0.32 mg/ml
Injection Remifentanil hydrochloride 20 µg/ml
NaCl 0,9% or Glucose 5% 1506
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Salbutamol sulfate
2090
Compatible
Injection Pantoprazole sodium 4 mg/ml
Injection Salbutamol sulfate 1 mg/ml
None 3216
Precipitation after 1 hour Incompatible
Injection Pantoprazole sodium
Injection Sodium bicarbonate
2090
Compatible
Injection Pantoprazole sodium 0,4 mg/ml
Injection Sulbactam/durlobactam 15/15 mg/ml
Sodium chloride 0,9% 4801
Compatible
Injection Pantoprazole sodium 0.4 mg/ml
Injection Tedizolid phosphate 0.8 mg/ml
Sodium chloride 0,9% 3827
Compatible
Injection Pantoprazole sodium 0.4 mg/ml
Injection Telavancin hydrochloride 7.5 mg/ml
NaCl 0,9% or Glucose 5% 3254
Compatible
Injection Pantoprazole sodium 0.4 mg/ml
Injection Telavancin hydrochloride 7.5 mg/ml
Ringer’s lactate solution 3254
Color change Incompatible
Injection Pantoprazole sodium 4 mg/ml
Injection Thiamine hydrochloride 1 mg/ml
Sodium chloride 0,9% 4698
Immediate precipitation Incompatible
Injection Pantoprazole sodium 4 mg/ml
Injection Thiopental sodium 25 mg/ml
Sodium chloride 0,9% 3767
Precipitation after 15 minutes Incompatible
Injection Pantoprazole sodium
Injection Thiopental sodium
2090
Compatible
Injection Pantoprazole sodium
Injection Ticarcillin / clavulanic acid
2090
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Tobramycin sulfate
2090
Color change after 6 hours Incompatible
Injection Pantoprazole sodium 8 mg/ml
Injection Vancomycin hydrochloride 40 mg/ml
2139
Compatible
Injection Pantoprazole sodium
Injection Vancomycin hydrochloride
2090
Compatible
Injection Pantoprazole sodium 0.16 >> 0.8 mg/ml
Injection Vasopressin 0.4 >> 1 UI/ml
Sodium chloride 0,9% 1902
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Vecuronium bromide
2090
Immediate precipitation Incompatible
Injection Pantoprazole sodium
Injection Verapamil hydrochloride
2090
Compatible
Injection Pantoprazole sodium
Injection Zidovudine
2090

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