Last update :
18/04/2024
Antibiotic   Cloxacillin sodium  
Injection
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Anaclosil Spain
Cloxa Iceland, Saudi Arabia
Cloxacilina Chile, Spain
Cloxacilina sodica Italy
Cloxacill Iran
Cloxacillin Canada, Iran, Malaysia, Norway
Ekvacillin Iceland, Sweden
Isoxacillin Malaysia
Klox India
Kloxerate Ireland
Meixam Malaysia, United States of America
Monoclox Malaysia
Orbenin Greece, Luxembourg, Saudi Arabia, Spain
Orbenine France, Tunisia
Staflocil Finland
Staphyclox Greece
Syntarpen Poland
Vaclox Malaysia
Compatibility   Injection   Compatibility : Cloxacillin sodium              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Aciclovir sodium 50 mg/ml
Water for Injection 3012
Chemical instability Incompatible
Injection Cloxacillin sodium
Injection Amikacin sulfate
3549
Subvisual incompatibility Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Amikacin sulfate 250 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Ringer’s lactate solution 4603
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Amiodarone hydrochloride 50 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Amoxicillin sodium / clavulanic acid 100/10 mg/ml
3824
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Amphotericin B liposomale 4 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Ampicillin sodium 250 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Atropine sulfate 0.4 mg/ml
Water for Injection 3012
Immediate precipitation Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Azithromycine 100 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Benztropine mesylate 1 mg/ml
Water for Injection 3012
Immediate precipitation Incompatible
Injection Cloxacillin sodium 8.6 mg/ml
Injection Blinatumomab 0.125 & 0.375 µg/ml
Sodium chloride 0,9% 3976
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Caffeine 10 mg/ml
None 3964
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Calcium chloride 100 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Calcium gluconate 100 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Caspofungin acetate 5 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Cefazolin sodium 10 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Cefotaxime sodium 95 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Cefoxitin sodium 100 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Ceftazidime 95 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Ceftriaxone disodium 100 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Cefuroxime sodium 90 mg/ml
Water for Injection 3012
Immediate precipitation Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Chlorpromazine hydrochloride 25 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Ciclosporin 5 mg/ml
Water for Injection 3012
Subvisual incompatibility Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Ciprofloxacin lactate 2 mg/ml
Water for Injection 3012
Unspecified incompatibility Incompatible
Injection Cloxacillin sodium
Injection Ciprofloxacin lactate
3529
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Clindamycin phosphate 150 mg/ml
Water for Injection 3012
Subvisual incompatibility Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Co-trimoxazole 80/16 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Dexamethasone sodium phosphate 4 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Dexmedetomidine 100 µg/ml
4389
Subvisual incompatibility Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Diazepam 5 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Digoxin 50 µg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Dimenhydrinate 10 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium
Injection Dimenhydrinate
2087
Immediate precipitation Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Diphenhydramine hydrochloride 50 mg/ml
Water for Injection 3012
Immediate precipitation Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Dobutamine hydrochloride 12,5 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Dopamine hydrochloride 3.2 mg/ml
Water for Injection 3012
Immediate precipitation Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Droperidol 2,5 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Epinephrine hydrochloride 1000 µg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Epinephrine hydrochloride 100 µg/ml
Water for Injection 3012
Unspecified incompatibility Incompatible
Injection Cloxacillin sodium
Injection Erythromycin lactobionate
3674
Immediate precipitation Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Erythromycin lactobionate 50 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Esmolol hydrochloride 10 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Fentanyl citrate 50 µg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Fluconazole 2 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Furosemide 10 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 20 mg/ml
Injection Furosemide 1 mg/ml
Sodium chloride 0,9% 1232
Unspecified incompatibility Incompatible
Injection Cloxacillin sodium
Injection Gentamicin sulfate
3643
Unspecified incompatibility Incompatible
Injection Cloxacillin sodium
Injection Gentamicin sulfate
3520
Immediate precipitation Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Gentamicin sulfate 40 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Heparin sodium 100 UI/ml
Water for Injection 3012
Color change after 4 hours Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Hydralazine hydrochloride 20 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Hydrocortisone sodium succinate 125 mg/ml
Water for Injection 3012
Immediate precipitation Incompatible
Injection Cloxacillin sodium 40 & 250 mg/ml
Injection Hydromorphone hydrochloride 2 >> 40 mg/ml
Glucose 5% 226
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Hydromorphone hydrochloride 10 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Insulin 100 UI/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Isoprenaline hydrochloride 0.2 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Ketamine hydrochloride 50 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Ketamine hydrochloride 50 mg/ml
2109
Immediate precipitation Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Labetalol hydrochloride 5 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Levofloxacine 5 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Lidocaine hydrochloride 1 mg/ml
Water for Injection 3012
Turbidity in 4 hours Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Lorazepam 4 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Magnesium sulfate 500 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Mannitol 250 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Meropenem 50 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 250 mg/ml
Injection Meropenem 50 mg/ml
Water for Injection 4319
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Methylprednisolone sodium succinate 62.5 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Metoclopramide hydrochloride 5 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Metronidazole 5 mg/ml
Water for Injection 3012
Immediate precipitation Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Midazolam hydrochloride 5 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Milrinone lactate 1 mg/ml
Water for Injection 3012
Immediate precipitation Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Morphine sulfate 50 mg/ml
Water for Injection 3012
Unspecified incompatibility Incompatible
Injection Cloxacillin sodium
Injection N-acetylcysteine 200 mg/ml
None 3766
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection N-acetylcysteine 200 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 250 mg/ml
Injection Naloxone hydrochloride 0.4 mg/ml
None 3408
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Naloxone hydrochloride 0.4 mg/ml
Water for Injection 3012
Turbidity in 4 hours Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Nitroglycerin 5 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Nitroprusside sodium 25 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Norepinephrine bitartrate 1 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Ondansetron hydrochloride 2 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Oxytocin 10 UI/ml
Water for Injection 3012
Immediate precipitation Incompatible
Injection Cloxacillin sodium
Injection Pantoprazole sodium
2090
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Pantoprazole sodium 4 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Paracetamol 10 mg/ml
4742
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Penicillin G sodium 0.5 MUI/ml
Water for Injection 3012
Precipitation after 1 hour Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Phenytoin sodium 50 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 10 mg/ml
Injection Phloroglucinol 2,5 mg/ml
3791
Subvisual incompatibility Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Piperacillin sodium 300 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Piperacillin sodium / tazobactam 225 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Potassium chloride 200 mEq/l
Water for Injection 3012
Subvisual incompatibility Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Potassium phosphate 3 mmol/ml
Water for Injection 3012
Immediate precipitation Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Promethazine hydrochloride 25 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Propranolol hydrochloride 1 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Ranitidine hydrochloride 25 mg/ml
Water for Injection 3012
Unspecified incompatibility Incompatible
Injection Cloxacillin sodium
Injection Rocuronium bromide
3564
Immediate precipitation Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Rocuronium bromide 10 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Salbutamol sulfate 1 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Salbutamol sulfate 1 mg/ml
None 3216
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Sodium bicarbonate 84 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Sufentanil citrate 0.05 mg/ml
Water for Injection 3012
Immediate precipitation Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Thiopental sodium 25 mg/ml
Sodium chloride 0,9% 3767
Subvisual incompatibility Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Ticarcillin / clavulanic acid 200/6,7 mg/ml
Water for Injection 3012
Immediate precipitation Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Tobramycin sulfate 40 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Valproic acid 100 mg/ml
Water for Injection 3012
Immediate precipitation Incompatible
Injection Cloxacillin sodium > 1.25 mg/ml
Injection Vancomycin hydrochloride > 2 mg/ml
Sodium chloride 0,9% 3557
Compatible
Injection Cloxacillin sodium < 1.25 mg/ml
Injection Vancomycin hydrochloride < 2 mg/ml
Sodium chloride 0,9% 3557
Immediate precipitation Incompatible
Injection Cloxacillin sodium 100 mg/ml
Injection Vancomycin hydrochloride 50 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 100 mg/ml
Injection Voriconazole 10 mg/ml
Water for Injection 3012
Compatible
Injection Cloxacillin sodium 10 mg/ml
Parenteral nutrition (binary mixture) 1055

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