Last update :
25/11/2020
References   References 4433  
Type : Journal
Web link : https://doi.org/10.1016/j.clinthera.2020.01.017

Research teams : Philadelphia - Philadelphia College of Pharmacy and Science
Authors : Ghazi I.M, El Nekidy W.S, Sood A, Dulku A, Patel R, Patel K.
Title : Y-site Administration of Imipenem/Cilastatin/ Relebactam With Common Intravenous Medications
Reference : Clin Ther ; 42, 3: 475-485. 2020

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
InjectionDexamethasone sodium phosphate Anti-inflammatory
Incompatible 1 mg/ml + InjectionImipenem-Cilastatin / Relebactam 5 mg/ml + NaCl 0,9% or Glucose 5%
InjectionFurosemide Diuretic
Incompatible 10 mg/ml + InjectionImipenem-Cilastatin / Relebactam 5 mg/ml + NaCl 0,9% or Glucose 5%
Oral solutionHaloperidol Neuroleptic
Incompatible 5 mg + InjectionImipenem-Cilastatin / Relebactam 5 mg/ml + Glucose 5%
InjectionHydrocortisone sodium succinate Anti-inflammatory
Incompatible 1 mg/ml + InjectionImipenem-Cilastatin / Relebactam 5 mg/ml + NaCl 0,9% or Glucose 5%
InjectionImipenem-Cilastatin / Relebactam Antibiotic
Incompatible 5 mg/ml + InjectionDexamethasone sodium phosphate 1 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 5 mg/ml + InjectionFurosemide 10 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 5 mg/ml + Oral solutionHaloperidol 5 mg + Glucose 5%
Incompatible 5 mg/ml + InjectionHydrocortisone sodium succinate 1 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 5 mg/ml + InjectionInsulin glulisine 1 U/ml + NaCl 0,9% or Glucose 5%
Incompatible 5 mg/ml + InjectionLabetalol hydrochloride 2 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 5 mg/ml + InjectionPhenytoin sodium 5 mg/ml + NaCl 0,9% or Glucose 5%
InjectionInsulin glulisine Glucose-lowering
Incompatible 1 U/ml + InjectionImipenem-Cilastatin / Relebactam 5 mg/ml + NaCl 0,9% or Glucose 5%
InjectionLabetalol hydrochloride Beta-blocker
Incompatible 2 mg/ml + InjectionImipenem-Cilastatin / Relebactam 5 mg/ml + NaCl 0,9% or Glucose 5%
InjectionPhenytoin sodium Antiepileptic
Incompatible 5 mg/ml + InjectionImipenem-Cilastatin / Relebactam 5 mg/ml + NaCl 0,9% or Glucose 5%

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