Last update :
16/07/2021
References   References 4521  
Type : Journal
Web link : https://doi.org/10.1515/pthp-2020-0011

Research teams : Nancy - University Hospital of Nancy, Department of Pharmacy
Authors : Polo C, D’Huart E, Lesperlette G, Vigneron J, Meyer F, Demoré B.
Title : Compatibility of injectable posaconazole with drugs commonly used in a hematology care unit.
Reference : Pharmaceutical Technology in Hospital Pharmacy 2020

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
InjectionAciclovir sodium Antiviral
Incompatible 3,5 mg/ml + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
InjectionAlizapride hydrochloride Antiemetic
Incompatible 3 mg/ml + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
InjectionCefepime dihydrochloride Antibiotic
Incompatible 40 mg/ml + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
InjectionFilgrastim Various
Compatible 3 µg/ml + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
InjectionFurosemide Diuretic
Incompatible 0,8 mg/ml + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
InjectionGanciclovir sodium Antiviral
Incompatible 3,5 mg/ml + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
InjectionInsulin aspart Glucose-lowering
Incompatible 100 UI/ml + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
InjectionLevetiracetam Antiepileptic
Incompatible 5 mg/ml + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
InjectionMethylprednisolone sodium succinate Anti-inflammatory
Incompatible 20 mg/ml + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
Incompatible 0,4 mg/ml + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
InjectionMetoclopramide hydrochloride Antiemetic
Incompatible 0,1 mg/ml + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
InjectionNefopam Analgesic
Incompatible 2,5 mg/ml + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
Incompatible 0,2 mg/ml + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
InjectionOndansetron hydrochloride Antiemetic
Incompatible 0,48 mg/ml + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
Incompatible 0,14 mg/ml + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
InjectionPantoprazole sodium Proton pump inhibitor
Incompatible 0,4 mg/ml + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
InjectionParacetamol Analgesic
Incompatible 10 mg/ml + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
InjectionPhloroglucinol  Antispasmodic
Incompatible 0,8 mg/ml + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
InjectionPiperacillin sodium / tazobactam Antibiotic
Incompatible 160 mg/ml + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
InjectionPosaconazole Antifungal
Incompatible 1,2 mg/ml + InjectionAciclovir sodium 3,5 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + InjectionAlizapride hydrochloride 3 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + InjectionCefepime dihydrochloride 40 mg/ml + Sodium chloride 0,9%
Compatible 1,2 mg/ml + InjectionFilgrastim 3 µg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + InjectionFurosemide 0,8 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + InjectionGanciclovir sodium 3,5 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + InjectionInsulin aspart 100 UI/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + InjectionLevetiracetam 5 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + InjectionMethylprednisolone sodium succinate 20 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + InjectionMethylprednisolone sodium succinate 0,4 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + InjectionMetoclopramide hydrochloride 0,1 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + InjectionNefopam 2,5 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + InjectionNefopam 0,2 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + InjectionOndansetron hydrochloride 0,48 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + InjectionOndansetron hydrochloride 0,14 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + InjectionPantoprazole sodium 0,4 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + InjectionParacetamol 10 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + InjectionPhloroglucinol 0,8 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + InjectionPiperacillin sodium / tazobactam 160 mg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + InjectionPotassium chloride 1341 mEq/l + Sodium chloride 0,9%
Compatible 1,2 mg/ml + InjectionTacrolimus 3 µg/ml + Sodium chloride 0,9%
Compatible 1,2 mg/ml + InjectionTacrolimus 30 µg/ml + Sodium chloride 0,9%
Incompatible 1,2 mg/ml + InjectionTramadol hydrochloride 0,5 mg/ml + Sodium chloride 0,9%
InjectionPotassium chloride Electrolyte
Incompatible 1341 mEq/l + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
InjectionTacrolimus Immunosuppressant
Compatible 3 µg/ml + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
Compatible 30 µg/ml + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%
InjectionTramadol hydrochloride Analgesic
Incompatible 0,5 mg/ml + InjectionPosaconazole 1,2 mg/ml + Sodium chloride 0,9%

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