Last update :
18/04/2024
References   References 1982  
Type : Journal

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Trissel LA, Ogundele AB.
Title : Compatibility of anidulafungin with other drugs during simulated Y-site administration.
Reference : Am J Health-Syst Pharm ; 62: 834-837. 2005

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
InjectionAciclovir sodium Antiviral
Compatible 7 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionAmikacin sulfate Antibiotic
Compatible 5 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionAminophylline Various
Compatible 2.5 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionAmphotericin B Antifungal
Incompatible 0,6 mg/ml + InjectionAnidulafungin 0,5 mg/ml + Glucose 5%
InjectionAmphotericin B cholesteryl sulfate complex Antifungal
Compatible 1 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionAmphotericin B liposomale Antifungal
Compatible 1 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionAmpicillin sodium Antibiotic
Compatible 20 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionAmpicillin sodium - sulbactam sodium Antibiotic
Compatible 20/10 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionAnidulafungin Antifungal
Factors which affect stability Solvent NaHCO3 Induces Degradation
Compatible 0.5 mg/ml + InjectionAciclovir sodium 7 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionAmikacin sulfate 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionAminophylline 2.5 mg/ml + Glucose 5%
Incompatible 0,5 mg/ml + InjectionAmphotericin B 0,6 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionAmphotericin B cholesteryl sulfate complex 1 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionAmphotericin B liposomale 1 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionAmpicillin sodium 20 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionAmpicillin sodium - sulbactam sodium 20/10 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionCarboplatin 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionCefazolin sodium 20 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionCefepime dihydrochloride 20 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionCefoxitin sodium 20 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionCeftazidime 40 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionCeftizoxime sodium 20 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionCeftriaxone disodium 20 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionCefuroxime sodium 30 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionCiclosporin 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionCimetidine hydrochloride 12 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionCiprofloxacin lactate 2 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionCisplatin 1 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionClindamycin phosphate 10 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionCo-trimoxazole 4/0.8 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionCyclophosphamide 10 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionCytarabine 50 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionDaunorubicin hydrochloride 1 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionDexamethasone sodium phosphate 1 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionDigoxin 250 µg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionDobutamine hydrochloride 4 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionDocetaxel 2 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionDopamine hydrochloride 3.2 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionDoxorubicin hydrochloride 2 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionEpinephrine hydrochloride 50 µg/ml + Glucose 5%
Incompatible 0.5 mg/ml + InjectionErtapenem 20 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionErythromycin lactobionate 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionEtoposide phosphate 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionFamotidine 2 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionFentanyl citrate 50 µg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionFluconazole 2 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionFluorouracil 16 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionFolinate calcium 2 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionFurosemide 3 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionGanciclovir sodium 20 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionGemcitabine hydrochloride 10 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionGentamicin sulfate 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionHeparin sodium 100 UI/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionHydrocortisone sodium succinate 1 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionHydromorphone hydrochloride 0.5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionIfosfamide 25 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionImipenem - cilastatin sodium 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionLinezolid 2 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionMeropenem 2.5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionMethylprednisolone sodium succinate 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionMetronidazole 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionMidazolam hydrochloride 1 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionMorphine sulfate 15 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionMycophenolate mofetil 6 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionPaclitaxel 0.6 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionPantoprazole sodium 0.4 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionPhenylephrine hydrochloride 1 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionPiperacillin sodium / tazobactam 40/5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionPotassium chloride 0.1 mEq/l + Glucose 5%
Compatible 0.5 mg/ml + InjectionQuinupristine/dalfopristine 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionRanitidine hydrochloride 2 mg/ml + Glucose 5%
Incompatible 0.5 mg/ml + InjectionSodium bicarbonate 84 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionTacrolimus 20 µg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionTicarcillin / clavulanic acid 31 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionTobramycin sulfate 5 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionVancomycin hydrochloride 10 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionVincristine sulfate 0.05 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionVoriconazole 4 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionZidovudine 4 mg/ml + Glucose 5%
Incompatible 0.5 mg/ml + NaHCO3
InjectionCarboplatin Anticancer drug
Compatible 5 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionCefazolin sodium Antibiotic
Compatible 20 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionCefepime dihydrochloride Antibiotic
Compatible 20 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionCefoxitin sodium Antibiotic
Compatible 20 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionCeftazidime Antibiotic
Compatible 40 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionCeftizoxime sodium Antibiotic
Compatible 20 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionCeftriaxone disodium Antibiotic
Compatible 20 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionCefuroxime sodium Antibiotic
Compatible 30 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionCiclosporin Immunosuppressant
Compatible 5 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionCimetidine hydrochloride Antihistamine (H2)
Compatible 12 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionCiprofloxacin lactate Antibiotic
Compatible 2 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionCisplatin Anticancer drug
Compatible 1 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionClindamycin phosphate Antibiotic
Compatible 10 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionCo-trimoxazole Antibiotic
Compatible 4/0.8 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionCyclophosphamide Anticancer drug
Compatible 10 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionCytarabine Anticancer drug
Compatible 50 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionDaunorubicin hydrochloride Anticancer drug
Compatible 1 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 1 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionDigoxin Cardiotonic
Compatible 250 µg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionDobutamine hydrochloride Cardiotonic
Compatible 4 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionDocetaxel Anticancer drug
Compatible 2 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionDopamine hydrochloride Cardiotonic
Compatible 3.2 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionDoxorubicin hydrochloride Anticancer drug
Compatible 2 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionEpinephrine hydrochloride Sympathomimetic
Compatible 50 µg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionErtapenem Antibiotic
Incompatible 20 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionErythromycin lactobionate Antibiotic
Compatible 5 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionEtoposide phosphate Anticancer drug
Compatible 5 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionFamotidine Antihistamine (H2)
Compatible 2 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionFentanyl citrate Analgesic
Compatible 50 µg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionFluconazole Antifungal
Compatible 2 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionFluorouracil Anticancer drug
Compatible 16 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionFolinate calcium Cytoprotective
Compatible 2 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionFurosemide Diuretic
Compatible 3 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionGanciclovir sodium Antiviral
Compatible 20 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionGemcitabine hydrochloride Anticancer drug
Compatible 10 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionGentamicin sulfate Antibiotic
Compatible 5 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionHeparin sodium Anticoagulant
Compatible 100 UI/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 1 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionHydromorphone hydrochloride Analgesic
Compatible 0.5 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionIfosfamide Anticancer drug
Compatible 25 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionImipenem - cilastatin sodium Antibiotic
Compatible 5 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionLevofloxacine Antibiotic
Compatible 5 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionLinezolid Antibiotic
Compatible 2 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionMeropenem Antibiotic
Compatible 2.5 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionMethylprednisolone sodium succinate Anti-inflammatory
Compatible 5 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionMetronidazole Antiparasitic
Compatible 5 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionMidazolam hydrochloride Anxiolytic
Compatible 1 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionMorphine sulfate Analgesic
Compatible 15 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionMycophenolate mofetil Immunosuppressant
Compatible 6 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionPaclitaxel Anticancer drug
Compatible 0.6 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionPantoprazole sodium Proton pump inhibitor
Compatible 0.4 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionPethidine hydrochloride Analgesic
Compatible 10 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionPhenylephrine hydrochloride Sympathomimetic
Compatible 1 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionPiperacillin sodium / tazobactam Antibiotic
Compatible 40/5 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionPotassium chloride Electrolyte
Compatible 0.1 mEq/l + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionQuinupristine/dalfopristine Antibiotic
Compatible 5 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionRanitidine hydrochloride Antihistamine (H2)
Compatible 2 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionSodium bicarbonate Electrolyte
Incompatible 84 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionTacrolimus Immunosuppressant
Compatible 20 µg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionTicarcillin / clavulanic acid Antibiotic
Compatible 31 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionTobramycin sulfate Antibiotic
Compatible 5 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionVancomycin hydrochloride Antibiotic
Compatible 10 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionVincristine sulfate Anticancer drug
Compatible 0.05 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionVoriconazole Antifungal
Compatible 4 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%
InjectionZidovudine Antiviral
Compatible 4 mg/ml + InjectionAnidulafungin 0.5 mg/ml + Glucose 5%

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