Last update :
01/10/2024
References   References 2108  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=2393

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Trusley C, Kupiec TC, Trissel LA.
Title : Compatibility of micafungin injection with other drugs during simulated Y-site co-administration.
Reference : Int J Pharm Compound ; 10: 230-232. 2006

Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Not rated: compatibility study only

List of drugs
injectionAminophylline Various
Compatible 2.5 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionAmiodarone hydrochloride Anti-arrhythmic
Incompatible 4 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionBumetanide Diuretic
Compatible 0.04 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionCalcium chloride Electrolyte
Compatible 40 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionCalcium gluconate Electrolyte
Compatible 40 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionCarboplatin Anticancer drug
Compatible 5 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionCiclosporin Immunosuppressant
Compatible 5 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionCisatracurium besylate Curarimimetic
Incompatible 0.5 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionDiltiazem hydrochloride Anti-arrhythmic
Incompatible 5 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionDobutamine hydrochloride Cardiotonic
Incompatible 4 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionDopamine hydrochloride Cardiotonic
Compatible 3.2 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionEpinephrine hydrochloride Sympathomimetic
Incompatible 50 µg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionEptifibatide Anticoagulant
Compatible 0.75 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionEsmolol hydrochloride Beta-blocker
Compatible 10 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionEtoposide Anticancer drug
Compatible 0.4 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionFenoldopam mesylate Vasodilator
Compatible 80 µg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionFurosemide Diuretic
Compatible 3 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionHeparin sodium Anticoagulant
Compatible 100 UI/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionHuman albumin Various
Incompatible 250 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionHydromorphone hydrochloride Analgesic
Compatible 0.5 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionInsulin Glucose-lowering
Incompatible 1 UI/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionLabetalol hydrochloride Beta-blocker
Incompatible 2 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionLidocaine hydrochloride Local anesthetic
Compatible 10 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionLorazepam Anxiolytic
Compatible 0.5 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionMagnesium sulfate Electrolyte
Compatible 100 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionMesna Cytoprotective
Compatible 20 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionMicafungin Antifungal
Compatible 1.5 mg/ml + Parenteral nutrition (binary mixture)
Compatible 1.5 mg/ml + injectionAminophylline 2.5 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + injectionAmiodarone hydrochloride 4 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionBumetanide 0.04 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionCalcium chloride 40 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionCalcium gluconate 40 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionCarboplatin 5 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionCiclosporin 5 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + injectionCisatracurium besylate 0.5 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + injectionDiltiazem hydrochloride 5 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + injectionDobutamine hydrochloride 4 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionDopamine hydrochloride 3.2 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + injectionEpinephrine hydrochloride 50 µg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionEptifibatide 0.75 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionEsmolol hydrochloride 10 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionEtoposide 0.4 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionFenoldopam mesylate 80 µg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionFurosemide 3 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionHeparin sodium 100 UI/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + injectionHuman albumin 250 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionHydromorphone hydrochloride 0.5 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + injectionInsulin 1 UI/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + injectionLabetalol hydrochloride 2 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionLidocaine hydrochloride 10 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionLorazepam 0.5 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionMagnesium sulfate 100 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionMesna 20 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + injectionMidazolam hydrochloride 2 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionMilrinone lactate 0.2 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + injectionMorphine sulfate 15 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + injectionMycophenolate mofetil 6 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + injectionNesiritide 0.006 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + injectionNicardipine hydrochloride 1 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionNitroglycerin 0.4 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionNitroprusside sodium 2 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionNorepinephrine bitartrate 0.128 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + injectionOctreotide acetate 0.005 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + injectionOndansetron hydrochloride 1 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + injectionPethidine hydrochloride 10 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionPhenylephrine hydrochloride 1 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + injectionPhenytoin sodium 50 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionPotassium chloride 100 mEq/l + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionPotassium phosphate 0.5 mmol/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + injectionRocuronium bromide 1 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionSodium Phosphate 0.5 mmol/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionTacrolimus 20 µg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionTheophylline 4 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + injectionVasopressin 1 UI/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + injectionVecuronium bromide 1 mg/ml + Sodium chloride 0,9%
injectionMidazolam hydrochloride Anxiolytic
Incompatible 2 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionMilrinone lactate Cardiotonic
Compatible 0.2 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionMorphine sulfate Analgesic
Incompatible 15 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionMycophenolate mofetil Immunosuppressant
Incompatible 6 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionNesiritide Vasodilator
Incompatible 0.006 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionNicardipine hydrochloride Vasodilator
Incompatible 1 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionNitroglycerin Vasodilator
Compatible 0.4 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionNitroprusside sodium Vasodilator
Compatible 2 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionNorepinephrine bitartrate Sympathomimetic
Compatible 0.128 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionOctreotide acetate Various
Incompatible 0.005 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionOndansetron hydrochloride Antiemetic
Incompatible 1 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionPethidine hydrochloride Analgesic
Incompatible 10 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionPhenylephrine hydrochloride Sympathomimetic
Compatible 1 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionPhenytoin sodium Antiepileptic
Incompatible 50 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionPotassium chloride Electrolyte
Compatible 100 mEq/l + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionPotassium phosphate Electrolyte
Compatible 0.5 mmol/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionRocuronium bromide Curarimimetic
Incompatible 1 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionSodium Phosphate Electrolyte
Compatible 0.5 mmol/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionTacrolimus Immunosuppressant
Compatible 20 µg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionTheophylline Various
Compatible 4 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionVasopressin Hormone
Compatible 1 UI/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
injectionVecuronium bromide Curarimimetic
Incompatible 1 mg/ml + injectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%

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