Last update :
14/06/2024
Vasodilator   Nicardipine hydrochloride  
Injection
Oral solution
Stability in solutions Stability of mixtures Factors which affect stability Compatibility Route of administration References Pdf
   Chemical structure  

Tradename   Tradename     

Trade names are indicative and excipients composition can be different depending on the country and manufacturers

Cardene Netherlands, United States of America
Cardepine Malaysia
Loxen France, Morocco, Tunisia
Nicardipine Belgium, Great Britain, Romania, United States of America
Perdipine Japan
Rycarden Sweden
Rydene Belgium, Luxembourg
Vasonase Spain
Compatibility   Injection   Compatibility : Nicardipine hydrochloride              
This screen indicates the compatibilities or incompatibilities with, in this case, the type of incompatibility (precipitation, color change, modification of an emulsion, etc.). The compatibilities shown here are mostly physical only, with the chemical stability of each molecule rarely being assessed. The evaluation of these mixtures was studied to consider the possibility of Y-site administration to the patient. These data cannot be used for making mixtures in advance in bags or syringes. This type of information is available in the screen "Stability in mixture ».
Compound Solvent References
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride
NaHCO3 3614
Compatible
Injection Nicardipine hydrochloride 0,2 mg/ml
Ringer’s lactate solution 4603
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Amikacin sulfate 2 mg/ml
NaCl 0,9% or Glucose 5% 1490
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride
Ringer’s lactate solution 3614
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Aminophylline 1 mg/ml
NaCl 0,9% or Glucose 5% 1490
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride 0.05 & 0.5 mg/ml
NaHCO3 44
Color change Incompatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Amoxicillin sodium / clavulanic acid 100/10 mg/ml
3824
Immediate turbidity Incompatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Ampicillin sodium 10 mg/ml
NaCl 0,9% or Glucose 5% 1490
Immediate turbidity Incompatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Ampicillin sodium - sulbactam sodium 15 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Aztreonam 10 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Butorphanol tartrate 0.4 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Calcium gluconate 19.8 mg/ml
NaCl 0,9% or Glucose 5% 1490
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Cefepime dihydrochloride 125 mg/ml
Water for Injection 2141
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Cefiderocol sulfate tosylate 20 mg/mL
NaCl 0,9% or Glucose 5% 4528
Precipitation after 4 hours Incompatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Cefoperazone sodium 10 mg/ml
NaCl 0,9% or Glucose 5% 1490
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride
NaHCO3 3941
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Cefazolin sodium 20 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Ceftazidime 10 mg/ml
NaCl 0,9% or Glucose 5% 1490
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Ceftazidime 125 mg/ml
Water for Injection 2141
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Ceftazidime 83.3 mg/ml
1759
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Ceftizoxime sodium 10 mg/ml
NaCl 0,9% or Glucose 5% 1490
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Ceftolozane / tazobactam 10/5 mg/ml
NaCl 0,9% or Glucose 5% 3828
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Chloramphenicol sodium succinate 10 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Cimetidine hydrochloride 3 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 0,5 mg/ml
Injection Cisatracurium besylate 1 mg/ml
Sodium chloride 0,9% 3429
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Clindamycin phosphate 9 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Co-trimoxazole 0.8/1.6 mg/ml
NaCl 0,9% or Glucose 5% 1490
Precipitation after 1 hour Incompatible
Injection Nicardipine hydrochloride 0.5 mg/ml
Injection Defibrotide 8 mg/ml
Sodium chloride 0,9% 3728
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride
Injection Diazepam
3614
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride
Injection Diazepam
3941
Compatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Diltiazem hydrochloride 1 mg/ml
314
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Dobutamine hydrochloride 1 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Dobutamine hydrochloride 4 mg/ml
314
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Dopamine hydrochloride 1.6 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Dopamine hydrochloride 3.2 mg/ml
314
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Enalaprilate 0.05 mg/ml
Sodium chloride 0,9% 1315
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Enalaprilate 0.5 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Epinephrine hydrochloride 20 µg/ml
314
Compatible
Injection Nicardipine hydrochloride 0,1 mg/ml
Injection Eravacycline 0,6 mg/ml
Sodium chloride 0,9% 4434
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Erythromycin lactobionate 5 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Esmolol hydrochloride 10 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Famotidine 0.2 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Fenoldopam mesylate 80 µg/ml
Sodium chloride 0,9% 1803
Compatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Fentanyl citrate 50 µg/ml
314
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Fentanyl citrate 2 µg/ml
NaCl 0,9% or Glucose 5% 1490
Immediate turbidity Incompatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Fosfomycin 30 mg/ml
NaCl 0,9% or Glucose 5% 4055
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Furosemide 10 mg/ml
314
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride
Injection Furosemide
3614
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride
Injection Furosemide
3941
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Gentamicin sulfate 0.8 mg/ml
NaCl 0,9% or Glucose 5% 1490
Unspecified incompatibility Incompatible
Injection Nicardipine hydrochloride
Injection Heparin sodium
3540
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Heparin sodium 40 UI/ml
NaCl 0,9% or Glucose 5% 1490
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Heparin sodium 100 UI/ml
314
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Hetastarch 60 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Hydrocortisone sodium succinate 2 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Hydromorphone hydrochloride 1 mg/ml
314
Compatible
Injection Nicardipine hydrochloride 0.2 mg/ml
Injection Isavuconazonium sulfate 1.5 mg/ml
NaCl 0,9% or Glucose 5% 3829
Compatible
Injection Nicardipine hydrochloride 0,2 mg/ml
Injection Ketamine hydrochloride 50 mg/ml
4389
Compatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Labetalol hydrochloride 2 mg/ml
314
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Labetalol hydrochloride 1 mg/ml
NaCl 0,9% or Glucose 5% 1490
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Lansoprazole 0.55 mg/ml
Sodium chloride 0,9% 1625
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Lidocaine hydrochloride 4 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Linezolid 2 mg/ml
None 1925
Compatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Lorazepam 0.5 mg/ml
314
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Magnesium sulfate 600 mg/ml
NaCl 0,9% or Glucose 5% 1490
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride
Injection Methohexital sodium
3614
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride
Injection Methohexital sodium
3941
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Methylprednisolone sodium succinate 0.8 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Metronidazole 5 mg/ml
NaCl 0,9% or Glucose 5% 1490
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Micafungin 1.5 mg/ml
Sodium chloride 0,9% 2108
Compatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Midazolam hydrochloride 2 mg/ml
314
Compatible
Injection Nicardipine hydrochloride 0,4 mg/ml
Injection Milrinone lactate 1 mg/ml
4506
Compatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Milrinone lactate 0.2 mg/ml
314
Compatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Morphine sulfate 2 mg/ml
314
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Morphine sulfate 0.2 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Nafcillin sodium 10 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Nefopam 0,16 mg/ml
Sodium chloride 0,9% 4698
Compatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Nitroglycerin 0.4 mg/ml
314
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Nitroprusside sodium 0.2 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Norepinephrine bitartrate 0.128 mg/ml
314
Compatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Paracetamol 10 mg/ml
4742
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Penicillin G potassium 0.05 MUI/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Piperacillin sodium 12 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Plazomicin sulfate 24 mg/ml
Sodium chloride 0,9% 4145
Compatible
Injection Nicardipine hydrochloride 0.05 & 0.5 mg/ml
Injection Potassium chloride 40 mEq/l
Glucose 5% 44
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Potassium chloride 400 mEq/l
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Potassium phosphate 0.44 mmol/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Ranitidine hydrochloride 0.5 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Ranitidine hydrochloride 1 mg/ml
314
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride
Injection Sodium bicarbonate
3614
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride 0,05 & 0,5 mg/ml
Injection Sodium bicarbonate 50 mg/ml
None 44
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride
Injection Sodium bicarbonate
3941
Compatible
Injection Nicardipine hydrochloride 0,1 mg/ml
Injection Sulbactam/durlobactam 15/15 mg/ml
Sodium chloride 0,9% 4801
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride 0.2 mg/ml
Injection Tedizolid phosphate 0.8 mg/ml
Sodium chloride 0,9% 3827
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Temocilline 83.33 mg/ml
Water for Injection 2231
Unspecified incompatibility Incompatible
Injection Nicardipine hydrochloride
Injection Temocilline
4470
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Thiopental sodium 25 mg/ml
314
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride
Injection Thiopental sodium
3941
Immediate precipitation Incompatible
Injection Nicardipine hydrochloride
Injection Thiopental sodium
3614
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Tobramycin sulfate 0.8 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 0.1 mg/ml
Injection Vancomycin hydrochloride 5 mg/ml
NaCl 0,9% or Glucose 5% 1490
Compatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Vancomycin hydrochloride 10 mg/ml
Glucose 5% 3385
Compatible
Injection Nicardipine hydrochloride 1 mg/ml
Injection Vecuronium bromide 1 mg/ml
314

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