Last update :
28/04/2024
References   References 1490  
Type : Journal

Research teams : Bronx - Bronx VA Medical Center, Surgical Intensive Care Unit
Authors : Halpern NA, Colucci RD, Alicea M, Greenstein R.
Title : The compatibility of nicardipine hydrochloride injection with various ICU medications during simulated Y-site injection.
Reference : Int J Pharm Clin Pharmacol Ther Tox ; 27: 250-254. 1989

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
InjectionAmikacin sulfate Antibiotic
Compatible 2 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionAminophylline Various
Compatible 1 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionAmpicillin sodium Antibiotic
Incompatible 10 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionAmpicillin sodium - sulbactam sodium Antibiotic
Incompatible 15 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionAztreonam Antibiotic
Compatible 10 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionButorphanol tartrate Analgesic
Compatible 0.4 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionCalcium gluconate Electrolyte
Compatible 19.8 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionCefazolin sodium Antibiotic
Compatible 20 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionCefoperazone sodium Antibiotic
Incompatible 10 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionCeftazidime Antibiotic
Compatible 10 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionCeftizoxime sodium Antibiotic
Compatible 10 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionChloramphenicol sodium succinate Antibiotic
Compatible 10 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionCimetidine hydrochloride Antihistamine (H2)
Compatible 3 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionClindamycin phosphate Antibiotic
Compatible 9 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionCo-trimoxazole Antibiotic
Compatible 0.8/1.6 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionDobutamine hydrochloride Cardiotonic
Compatible 1 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionDopamine hydrochloride Cardiotonic
Compatible 1.6 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionEnalaprilate Antihypertensive
Compatible 0.5 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionErythromycin lactobionate Antibiotic
Compatible 5 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionEsmolol hydrochloride Beta-blocker
Compatible 10 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionFamotidine Antihistamine (H2)
Compatible 0.2 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionFentanyl citrate Analgesic
Compatible 2 µg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionGentamicin sulfate Antibiotic
Compatible 0.8 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionHeparin sodium Anticoagulant
Compatible 40 UI/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionHetastarch Various
Compatible 60 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 2 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionLabetalol hydrochloride Beta-blocker
Compatible 1 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionLidocaine hydrochloride Local anesthetic
Compatible 4 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionMagnesium sulfate Electrolyte
Compatible 600 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionMethylprednisolone sodium succinate Anti-inflammatory
Compatible 0.8 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionMetronidazole Antiparasitic
Compatible 5 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionMorphine sulfate Analgesic
Compatible 0.2 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionNafcillin sodium Antibiotic
Compatible 10 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionNicardipine hydrochloride Vasodilator
Compatible 0.1 mg/ml + InjectionAmikacin sulfate 2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionAminophylline 1 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 0.1 mg/ml + InjectionAmpicillin sodium 10 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 0.1 mg/ml + InjectionAmpicillin sodium - sulbactam sodium 15 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionAztreonam 10 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionButorphanol tartrate 0.4 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionCalcium gluconate 19.8 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionCefazolin sodium 20 mg/ml + NaCl 0,9% or Glucose 5%
Incompatible 0.1 mg/ml + InjectionCefoperazone sodium 10 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionCeftazidime 10 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionCeftizoxime sodium 10 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionChloramphenicol sodium succinate 10 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionCimetidine hydrochloride 3 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionClindamycin phosphate 9 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionCo-trimoxazole 0.8/1.6 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionDobutamine hydrochloride 1 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionDopamine hydrochloride 1.6 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionEnalaprilate 0.5 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionErythromycin lactobionate 5 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionEsmolol hydrochloride 10 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionFamotidine 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionFentanyl citrate 2 µg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionGentamicin sulfate 0.8 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionHeparin sodium 40 UI/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionHetastarch 60 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionHydrocortisone sodium succinate 2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionLabetalol hydrochloride 1 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionLidocaine hydrochloride 4 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionMagnesium sulfate 600 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionMethylprednisolone sodium succinate 0.8 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionMetronidazole 5 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionMorphine sulfate 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionNafcillin sodium 10 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionNitroprusside sodium 0.2 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionPenicillin G potassium 0.05 MUI/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionPiperacillin sodium 12 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionPotassium chloride 400 mEq/l + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionPotassium phosphate 0.44 mmol/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionRanitidine hydrochloride 0.5 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionTobramycin sulfate 0.8 mg/ml + NaCl 0,9% or Glucose 5%
Compatible 0.1 mg/ml + InjectionVancomycin hydrochloride 5 mg/ml + NaCl 0,9% or Glucose 5%
InjectionNitroprusside sodium Vasodilator
Compatible 0.2 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionPenicillin G potassium Antibiotic
Compatible 0.05 MUI/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionPiperacillin sodium Antibiotic
Compatible 12 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionPotassium chloride Electrolyte
Compatible 400 mEq/l + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionPotassium phosphate Electrolyte
Compatible 0.44 mmol/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionRanitidine hydrochloride Antihistamine (H2)
Compatible 0.5 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionTobramycin sulfate Antibiotic
Compatible 0.8 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%
InjectionVancomycin hydrochloride Antibiotic
Compatible 5 mg/ml + InjectionNicardipine hydrochloride 0.1 mg/ml + NaCl 0,9% or Glucose 5%

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