Laatste update :
18/04/2024
Lokaalanestheticum   Lidocaine hydrochloride  
Injecteerbaar geneesmiddel
Gorgelen Zalf
Stabiliteit in oplossing Stabiliteit in mengsels Factoren die de stabiliteit beïnvloeden Verenigbaarheden Toedieningswijze Literatuur Pdf
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Merknamen in verschillende landen   Merknamen in verschillende landen     

Handelsnamen zijn slechts een indicatie; de samenstelling van hulpstoffen kan per land variëren afhankelijk van de fabrikant

Jetokaine Turkije
Lidocard Finland
Lidocorit Oostenrijk
Lidosen Italië
Lidrian Italië
Linisol België
Locaine Zuid-Afrika
Minijet lignocaine Groot Britannië
Pisacaina Ecuador, Mexico
Plidocain Polen
Rapidocain Zwitserland
Remicaine Zuid-Afrika
Remicard Zuid-Afrika
Xilina Roemenië
Xylanest Oostenrijk
Xylesine Zwitserland
Xylestesin Brazilië
Xylocain Canada, Denemarken, Finland, Noorwegen, Oostenrijk, Polen, Zweden, Zwitserland
Xylocaina Brazilië, Italië
Xylocaine Australië, België, Canada, Frankrijk, Griekenland, Luxemburg, Maleisië, Marokko, Nederland, Slovenië, USA
Xylocard Australië, België, Canada, Egypte, Frankrijk, Oostenrijk, Portugal, Saudi-Arabië, Zweden
Xylocitin Duitsland
Xyloneural Oostenrijk, Zwitserland
Literatuur   Injecteerbaar geneesmiddel   Literatuur : Lidocaine hydrochloride  
Type Publicatie
59 Artikel Trissel LA, Gilbert DL, Martinez JF, Kim MC.
Compatibility of remifentanil hydrochloride with selected drugs during simulated Y-site administration.
Am J Health-Syst Pharm 1997 ; 54: 2192-2196.
62 Artikel Pugh CB, Pabis DJ, Rodriguez C.
Visual compatibility of morphine sulfate and meperidine hydrochloride with other injectable drugs during simulated Y-site injection.
Am J Hosp Pharm 1991 ; 48: 123-125.
92 Artikel Lee CY, Mauro VF, Alexander KS.
Visual and spectrophotometric determination of compatibility of alteplase and streptokinase with other injectable drugs.
Am J Hosp Pharm 1990 ; 47: 606-608.
187 Artikel Olsen KM, Gurley BJ, Davis GA, Christensen R, Monaghan MS.
Stability of flumazenil with selected drugs in 5% dextrose injection.
Am J Hosp Pharm 1993 ; 50: 1907-1912.
198 Artikel Gayed AA, Kheshary PR, Hinkle RL.
Visual compatibility of diltiazem injection with various diluents and medications during simulated Y-site injection.
Am J Health-Syst Pharm 1995 ; 52: 516-520.
210 Artikel Stewart JT, Warren FW, King AD.
Stability of ranitidine hydrochloride and seven medications.
Am J Hosp Pharm 1994 ; 51: 1802-1807.
214 Artikel Galante LJ, Stewart JT, Warren FW, Edgar JW, Huff AJ.
Stability of ranitidine hydrochloride with eight medications in intravenous admixtures.
Am J Hosp Pharm 1990 ; 47: 1606-1610.
240 Artikel Lam XM, Ward CA, de C du M?e CPR.
Stability and activity of alteplase with injectable drugs commonly used in cardiac therapy.
Am J Health-Syst Pharm 1995 ; 52: 1904-1909.
242 Artikel Campbell S, Nolan PE, Bliss M, Wood R, Mayersohn M.
Stability of amiodarone hydrochloride in admixtures with other injectable drugs.
Am J Hosp Pharm 1986 ; 43: 917-921.
278 Artikel Hagan RL, Carr-Lopez S, Strickland JS.
Stability of nafcillin sodium in the presence of lidocaine hydrochloride.
Am J Health-Syst Pharm 1995 ; 52: 521-523.
279 Artikel Bailey LC, Cappel KM, Orosz ST.
Stability of ceftriaxone sodium in injectable solutions stored frozen in syringes.
Am J Hosp Pharm 1994 ; 51: 2159-2161.
288 Artikel Cervenka P, Dejong DJ, Butler BL, Monzingo MD.
Visual compatibility of injectable ciprofloxacin lactate with selected injectable drugs during simulated Y-site administration.
Hosp Pharm 1992 ; 27: 957-958,961-962.
299 Artikel Trissel LA, Martinez JF, Gilbert DL.
Compatibility of cisatracurium besylate with selected drugs during simulated Y-site administration.
Am J Health-Syst Pharm 1997 ; 54: 1735-1741.
300 Artikel Trissel LA, Gilbert DL, Martinez JF.
Compatibility of propofol injectable emulsion with selected drugs during simulated Y-site administration.
Am J Health-Syst Pharm 1997 ; 54: 1287-1292.
315 Artikel Bahal SM, Lee TJ, McGinnes M, Dobler GL.
Visual compatibility of warfarin sodium injection with selected medications and solutions.
Am J Health-Syst Pharm 1997 ; 54: 2599-2600.
317 Artikel Kershaw BP, Monnier HL, Mason JH.
Visual compatibility of premixed theophylline or heparin with selected drugs for IV administration.
Am J Hosp Pharm 1993 ; 50: 1360-1362.
319 Artikel Hadzija BW, Lubarsky DA.
Compatibility of etomidate, thiopental sodium, and propofol injections with drugs commonly administered during induction of anesthesia.
Am J Health-Syst Pharm 1995 ; 52: 997-999.
386 Artikel Colucci RD, Cobuzzi LE, Halpern NA.
Visual compatibility of labetalol hydrochloride injection with various injectable drugs during simulated Y-site injection.
Am J Hosp Pharm 1988 ; 45: 1357-1358.
397 Artikel Fong PA, Ward J.
Visual compatibility of intravenous famotidine with selected drugs.
Am J Hosp Pharm 1989 ; 46: 125-126.
398 Artikel Jay GT, Fanikos J, Souney PF.
Visual compatibility of famotidine with commonly used critical-care medications during simulated Y-site injection.
Am J Hosp Pharm 1988 ; 45: 1556-1557.
403 Artikel Outman WR, Monolakis J.
Visual compatibility of haloperidol lactate with 0.9% sodium chloride injection or injectable critical-care drugs during simulated Y-site injection.
Am J Hosp Pharm 1991 ; 48: 1539-1541.
499 Artikel Rockwell K, Burch K.
Intramuscular antibiotic preparation and administration using a 1% lidocaine diluent: policies for the pediatric patient.
Hosp Pharm 1991 ; 26: 634-635.
524 Artikel Farquhar Zanetti LA.
Visual compatibility of diltiazem with commonly used injectable drugs during simulated Y-site administration.
Am J Hosp Pharm 1992 ; 49: 1911.
612 Artikel Frable RA, Klink PR, Engel GL, Mundell EE.
Stability of cefamandole nafate injection with parenteral solutions and additives.
Am J Hosp Pharm 1982 ; 39: 622-627.
619 Artikel Kirschenbaum HL, Aronoff W, Perentesis GP, Plitz GW, Cutie AJ.
Stability and compatibility of lidocaine hydrochloride with selected large-volume parenterals and drugs additives.
Am J Hosp Pharm 1982 ; 39: 1013-1015.
626 Artikel Bornstein M, Lo AY, Thomas PN, Wilham WL.
Moxalactam disodium compatibility with intramuscular and intravenous diluents.
Am J Hosp Pharm 1982 ; 39: 1495-1498.
660 Artikel Michaels MR, Stauffer GL, Haas DP.
Propofol compatibility with other intravenous drug products - Two new methods of evaluating IV emulsion compatibility.
Ann Pharmacotherapy 1996 ; 30: 228-232.
705 Artikel Lee YC, Malick W, Amann AH, Baaske DM, Shah JJ, Wagenknecht DM, Carter JE.
Bretylium tosylate admixture compatibility. II : Dopamine, lidocaine, procainamide, and nitroglycerin.
Am J Hosp Pharm 1981 ; 38: 183-187.
706 Artikel Cutie MR.
Compatibility of verapamil hydrochloride with other additives.
Am J Hosp Pharm 1981 ; 38: 231.
730 Artikel Allen LV, Saul Levinson R, Phisutsinthop D.
Compatibility of various admixtures with secondary additives at Y-injection site of intravenous administration sets.
Am J Hosp Pharm 1977 ; 34: 939-943.
738 Artikel Gardella LA, Kesler H, Amann A, Carter JE.
Intropin (dopamine hydrochloride) intravenous admixture compatibility. Part 3: Stability with miscellaneous additives.
Am J Hosp Pharm 1978 ; 35: 581-584.
794 Artikel Lilley EMM, Isert PR, Carasso ML, Kennedy RA.
The effect of the addition of lignocaine on propofol emulsion stability.
Anaesthesia 1996 ; 51: 815-818.
921 Artikel Trissel LA, Gilbert DL, Martinez JF.
Incompatibility and compatibility of amphotericin B cholesteryl sulfate complex with selected other drugs during simulated Y-site administration.
Hosp Pharm 1998 ; 33: 284-292.
925 Artikel Dupuis LL, Trope A, Giesbrecht E, Wong B.
Compatibility and stability of propafenone hydrochloride with five critical-care medications.
Can J Hosp Pharm 1998 ; 51: 55-57.
1036 Artikel Hasegawa GR, Eder JF.
Visual compatibility of amiodarone hydrochloride injection with other injectable drugs.
Am J Hosp Pharm 1984 ; 41: 1379-1380.
1041 Artikel Hasegawa GR, Eder JF.
Visual compatibility of dobutamine hydrochloride with other injectable drugs.
Am J Hosp Pharm 1984 ; 41: 949-951.
1049 Artikel Klamerus KJ, Ueda CT, Newton DW.
Stability of nitroglycerin in intravenous admixtures.
Am J Hosp Pharm 1984 ; 41: 303-305.
1058 Artikel Kirschenbaum HL, Aronoff W, Piltz GW, Perentesis GP, Cutie AJ.
Compatibility and stability of dobutamine hydrochloride with large-volume parenterals and selected additives.
Am J Hosp Pharm 1983 ; 40: 1690-1691.
1072 Artikel Saltsmann CL, Tom CM, Mitchell A, Fan JH, Gailey RA.
Compatibility of levofloxacin with 34 medications during simulated Y-site administration.
Am J Health-Syst Pharm 1999 ; 56: 1458-1459.
1126 Artikel Lackner TE, Baldus D, Butler CD, Amyx C, Kessler G.
Lidocaine stability in cardioplegic solution stored in glass bottles and polyvinyl chloride bags.
Am J Hosp Pharm 1983 ; 40: 97-101.
1193 Artikel Perentesis GP, Plitz GW, Kirschenbaum HL, Navalakha P, Aronoff W, Cutie AJ.
Stability and visual compatibility of bretylium tosylate with selected large-volume parenterals and additives.
Am J Hosp Pharm 1983 ; 40: 1010-1012.
1201 Artikel Yuhas EM, Lofton FT, Rosenberg HA, Mayron D, Baldinus JG.
Cimetidine hydrochloride compatibility III: Room temperature stability in drug admixtures.
Am J Hosp Pharm 1981 ; 38: 1919-1922.
1202 Artikel Smith FM, Nuessle NO.
Stability of lidocaine hydrochloride in 5% dextrose injection in plastic bags.
Am J Hosp Pharm 1981 ; 38: 1745-1747.
1232 Artikel Beatson C, Taylor A.
A physical compatibility study of furosemide & flucloxacillin injections.
Br J Pharm Pract 1987 ; 9: 223-226, 236.
1315 Artikel Halpern NA, Colucci RD, Alicea M, Greenstein R.
Visual compatibility of enalaprilat with commonly used critical care medications during simulated Y-site injection.
Int J Pharm Clin Pharmacol Ther Tox 1989 ; 27: 294-297.
1331 Artikel Das Gupta V, Steward KR.
Chemical stabilities of lignocaine hydrochloride and phenylephrine hydrochloride in aqueous solution.
J Clin Hosp Pharm 1986 ; 11 : 449-452.
1338 Artikel Baptista RJ, Dumas GJ, Bistrian BR, Condella F, Blackburn GL.
Compatibility of total nutrient admixtures and secondary cardiovascular medications.
Am J Hosp Pharm 1985 ; 42: 777-778.
1420 Artikel Bergquist PA, Hunke WA, Reed RA, Manas D, Forsyth RJ, Kenney RR, Cook J, Holahan M.
Compatibility of tirofiban HCl with dopamine HCl, famotidine, sodium heparin, lidocaine HCl and potassium chloride during simulated Y-site administration.
J Clin Pharm Ther 1999 ; 24: 125-132.
1490 Artikel Halpern NA, Colucci RD, Alicea M, Greenstein R.
The compatibility of nicardipine hydrochloride injection with various ICU medications during simulated Y-site injection.
Int J Pharm Clin Pharmacol Ther Tox 1989 ; 27: 250-254.
1512 Fabrikant Tirofiban (Aggrastat®) - Summary of Product Characteristics
Beacon Pharmaceuticals Ltd 2015
1625 Artikel Trissel LA, Saenz C, Williams YW, Ingram D.
Incompatibilities of lansoprazole injection with other drugs during simulated Y-site coadministration.
Int J Pharm Compound 2001 ; 5: 314-321.
1712 Artikel Trissel LA, Saenz CA.
Compatibility screening of Precedex during simulated Y-site administration with other drugs.
Int J Pharm Compound 2002 ; 6: 230-233.
1713 Artikel Trissel LA, Saenz CA.
Compatibility screening of bivalirudin during simulated Y-site administration with other drugs.
Int J Pharm Compound 2002 ; 6: 311-315.
1715 Artikel Storms ML, Stewart JT, Warren FW.
Stability of lidocaine hydrochloride injection at ambient temperature and 4°C in polypropylene syringes.
Int J Pharm Compound 2002 ; 6: 388-390.
1721 Artikel Trissel LA, Williams KY, Baker MB.
Compatibility screening of Hextend during simulated Y-site administration with other drugs.
Int J Pharm Compound 2001 ; 5: 69-72.
1801 Artikel Feddema S, Rusho WJ, Tyler LS, Barker B.
Physical compatibility of vasopressin with medications commonly used in cardiac arrest.
Am J Health-Syst Pharm 2003 ; 60: 1271-1272.
1803 Artikel Trissel, LA, Saenz CA, Ogundele OB, Ingram D, Baker MB.
Compatibility of fenoldopam mesylate with other drugs during simulated Y-site administration.
Am J Health-Syst Pharm 2003 ; 60: 80-85.
1925 Artikel Trissel LA , Williams KY, Gilbert DL.
Compatibility screening of linezolid injection during simulated Y-site administration with other drugs and infusion solutions.
J Am Pharm Assoc 2000 ; 40: 515-519.
1937 Artikel Lai JJ, Brodeur SK.
Physical and chemical stability of daptomycin with nine medications.
Ann Pharmacotherapy 2004 ; 38: 1612-1616.
1963 Artikel Honisko ME, Fink JM, Militello MA, Mauro VF, Alexander KS.
Compatibility of argatroban with selected cardiovascular agents.
Am J Health-Syst Pharm 2004 ; 61: 2415-2418.
2053 Artikel Masaki Y, Tanaka M, Nishikawa T.
Physicochemical compatibility of propofol-lidocaine mixture.
Anesth Analg 2003 ; 97: 1646-1651.
2090 Artikel Pere H, Chasse V, Forest JM, Hildgen P.
Compatibility of injectable pantoprazole in Y-site administration.
Pharmactuel 2004 ; 37: 193-196.
2108 Artikel Trusley C, Kupiec TC, Trissel LA.
Compatibility of micafungin injection with other drugs during simulated Y-site co-administration.
Int J Pharm Compound 2006 ; 10: 230-232.
2269 Artikel Chan P, Bishop A, Kupiec TC, Trissel LA, Gole D, Jimidar IM, Vermeersch H.
Compatibility of ceftobiprole medocaril with selected drugs during simulated Y-site administration.
Am J Health-Syst Pharm 2008 ; 65, 16: 1545-1551.
2271 Fabrikant Daptomycine (Cubicin®) Résumé des caractéristiques du produits
Novartis 2006
2279 Artikel Kupiec T, Trusley C, Ben M, Trissel LA.
Physical and chemical stability of palonosetron hydrochloride with five common parenteral drugs during simulated Y-site administration.
Am J Health-Syst Pharm 2008 ; 65, 18: 1735-1759.
2346 Artikel Newland A.M, Mauro V.F, Alexander K.S.
Physical compatibility of metoprolol tartrate injection with selected cardiovascular agents
Am J Health-Syst Pharm 2009 ; 66: 986-987.
2878 Artikel Pascuet E, Donnelly RF, Garceau D, Vaillancourt R.
Buffered Lidocaine Hydrochloride Solution With and Without Epinephrine: Stability in Polypropylene Syringes.
Can J Hosp Pharm 2009 ; 62, 5: 375-380.
3012 Artikel Sullivan T, Forrest J.M, Leclair G.
Compatibility of Cloxacillin Sodium with Selected Intravenous Drugs During Simulated Y-Site Administration
Hosp Pharm 2015 ; 50, 3: 214-220.
3184 Fabrikant
Hyaluronidase (Hyalase®) - Summary of Product characteristics.
CP Pharmaceuticals 2005
3249 Artikel Singh BM, Dedhiya MG, Dinunzio J, Chan P, Kupiec TC, Trissel LA, Laudano JB.
Compatibility of ceftaroline fosamil for injection with selected drugs during simulated Y-site administration.
Am J Health-Syst Pharm 2011 ; 68: 2163-2169.
3263 Artikel Donnelly R.F.
Stability of buffered lidocaine in glass vials.
Can J Hosp Pharm 2011 ; 64, 4: 289-290.
3332 Fabrikant Tigecycline (Tigacyl®) - Summary of Product characteristics
Pfizer 2012
3408 Artikel Tollec S, Touzin K, Pelletier E, Forest J.M.
Evaluation visuelle de la compatibilité physique de la naloxone avec d’autres médicaments intraveineux usuels.
Pharmactuel 2013 ; 46, 1 : 16-21.
3420 Artikel El Kateb N, Chaussard M, Bellenger P, Petit A, Faure P.
Stability of an extemporaneously prepared bleomycin-lidocaine-epinephrine intradermal admixture used in dermatology
J Oncol Pharm Practice 2014 ; 21, 3: 178-187.
3502 Fabrikant Propofol (Diprivan®) - Summary of Products Characteristics
Astra Zeneca 2012
3546 Fabrikant Cefamandole Flavelab - Résumé des caractéristiques du produit
Panpharma SA 2007
3687 Fabrikant Cefuroxime sodium - Summary of Product Characteristics
Stravencon 2013
3766 Artikel Forrest J.M, Hildgen P.
Compatibilité de l’acétylcystéine injectable lors de son administration en Y avec d’autres médicaments usuels
Pharmactuel 2014 ; 47, 3 : 161-165.
3824 Artikel Boudi S, Roy H, Forest JM, Leclair G.
Compatibilité physique de l'association amoxicilline-acide clavulanique en injection avec plusieurs autres médicaments lors d'une administration en Y.
Pharmactuel 2023 2023;56,3:91-98
3827 Poster Ghazi I.M, Hamada Y, Nicolau D.P.
Compatibility of tedizolid phosphate with selected intravenous drugs via simulated Y-site conditions.
ASHP Midyear 2015
3828 Poster Thabit A.K, Hamada Y, Nicolau D.P.
Ceftozolane/tazobactam physical compatibility during simulated Y-site administration.
ASHP Midyear 2015
3829 Poster So W, Kim L, Thabit A.K, Nicolau D.P, Kuti J.L.
Compatibility of isavunazonium sulfate during simulated Y-site administration.
ASHP Midyear 2015
3932 Fabrikant Hydroxocobalamine (Cyanokit®) - Résumé des caractéristiques du produit
Serb Laboratoire 2015
3934 Fabrikant Eptifibatide (Integrilin®) - Résumé des caractéristiques du produit
GlaxoSmithKline Laboratoire 2016
3964 Artikel Audet M.A, Forest E, Friciu M, Forest J.M, Leclair G.
Compatibilité du citrate de caféine injectable avec plusieurs autres médicaments.
Pharmactuel 2017 ; 50,1 : 27-33.
4055 Artikel Monogue M, Almarzoky Abuhussain S, Kuti J, Nicolau D.
Physical compatibility of fosfomycin for injection with select i.v. drugs during simulated Y-site administration.
Am J Health-Syst Pharm 2018 , 75, 1:36-44
4145 Artikel Asempa T.E, Avery L.M, Kidd J.M, Kuti J.L, Nicolau D.P.
Physical compatibility of plazomicin with select i.v. drugs during simulated Y-site administration.
Am J Health-Syst Pharm 2018 ;75,14:1048-1056
4319 Artikel Lessard J-J, Caron E, Schérer H, Forest J-M, Leclair G.
Compatibility of Y-site Injection of Meropenem Trihydrate With 101 Other Injectable Drugs.
Hosp Pharm 2020 ; 55, 5: 332-337.
4350 Artikel Beiler B, Barraud D, Vigneron J, Demor? B.
Physicochemical stability of an admixture of lidocaine and ketamine in polypropylene syringe used in opioid-free anaesthesia.
EJHP 2019 ;0:1-5
4433 Artikel Ghazi I.M, El Nekidy W.S, Sood A, Dulku A, Patel R, Patel K.
Y-site Administration of Imipenem/Cilastatin/ Relebactam With Common Intravenous Medications
Clin Ther 2020 ; 42, 3: 475-485.
4457 Artikel Houlihan, S, Decarie, D, Benes, C, Cleve, R, Vidler M, Magee L.A, Ensom M.H.H, vonDadelszen P.
Magnocaine: Physical Compatibility and Chemical Stability of Magnesium Sulphate and Lidocaine Hydrochloride in Prefilled Syringes.
J Obstet Gynaecol Can 2016 ;38,10:936e944.
4528 Artikel Lu J, Liu Q, Kupiec T, Vail H, Lunch L, Fam D, Vu N.
Physical Compatibility of Cefiderocol with Selected Intravenous Drugs During Simulated Y-site Administration.
Int J Pharm Compound 2021 ;25,1:52-61
4603 Artikel Vallée M, Barthélémy I, Friciu M, Pelletier E, Forest J.M, Benoit F, Leclair G.
Compatibility of Lactated Ringer’s Injection With 94 Selected Intravenous Drugs During Simulated Y-site Administration.
Hosp Pharm 2021 ; 56, 4: 228-234.
4650 Fabrikant Ceftobiprole (Zevtera 500 mg powder for concentrate for solution for infusion.) Summary of Product Characteristics, Advanz Pharma updated 4 aug 2021.
Advanz Pharma 2021
4742 Artikel Macoviciuc M, Nguyen C, Forest J-M, Leclair G.
Compatibilité physique de l’acétaminophène injectable avec 102 autres médicaments lors d’une administration en Y.
Pharmactuel 2022 ; 55, 4: 247-255.

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