Last update :
24/11/2020
References   References 4457  
Type : Journal
Web link : http://dx.doi.org/10.1016/j.jogc.2016.04.097

Research teams : Vancouver - Children\'s and Women\'s Health Center of British Columbia
Authors : Houlihan, S, Decarie, D, Benes, C, Cleve, R, Vidler M, Magee L.A, Ensom M.H.H, vonDadelszen P.
Title : Magnocaine: Physical Compatibility and Chemical Stability of Magnesium Sulphate and Lidocaine Hydrochloride in Prefilled Syringes.
Reference : J Obstet Gynaecol Can ;38,10:936e944. 2016

Level of Evidence : 
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 

List of drugs
InjectionLidocaine hydrochloride Local anesthetic
InjectionMagnesium sulfate Electrolyte
Stability of mixtures
Polypropylen Syringe None 25°C Protect from light
Injection Lidocaine hydrochloride 455 mg/ml
Injection Magnesium sulfate 2 mg/ml
168 Day
Polypropylen Syringe None 40°C Protect from light
Injection Magnesium sulfate 2 mg/ml
Injection Lidocaine hydrochloride 455 mg/ml
168 Day

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