Last update :
28/04/2024
References   References 405  
Type : Journal

Research teams : Boston - Brigham and women\'s hospital
Authors : Nieves-Cordero AL, Luciw HM, Souney PF.
Title : Compatibility of narcotic analgesic solutions with various antibiotics during simulated Y-site injection.
Reference : Am J Hosp Pharm ; 42: 1108-1109. 1985

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
InjectionAmikacin sulfate Antibiotic
Compatible 5 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionAmpicillin sodium Antibiotic
Compatible 20 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
InjectionCefalotin sodium Antibiotic
Compatible 20 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionCefamandole nafate Antibiotic
Compatible 20 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionCefazolin sodium Antibiotic
Compatible 20 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
InjectionCefoperazone sodium Antibiotic
Compatible 20 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Incompatible 20 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
Incompatible 20 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionCeforanide Antibiotic
Compatible 20 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionCefotaxime sodium Antibiotic
Compatible 20 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionCefoxitin sodium Antibiotic
Compatible 20 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionCeftizoxime sodium Antibiotic
Compatible 20 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionCefuroxime sodium Antibiotic
Compatible 30 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 30 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 30 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionChloramphenicol sodium succinate Antibiotic
Compatible 20 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionClindamycin phosphate Antibiotic
Compatible 12 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 12 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 12 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionCo-trimoxazole Antibiotic
Compatible 4/0.8 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 4/0.8 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 4/0.8 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionDoxycycline hyclate Antibiotic
Compatible 1 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionErythromycin lactobionate Antibiotic
Compatible 5 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionGentamicin sulfate Antibiotic
Compatible 0.8 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 0.8 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 0.8 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionHydromorphone hydrochloride Analgesic
Compatible 0.2 mg/ml + InjectionAmikacin sulfate 5 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionAmpicillin sodium 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionCefalotin sodium 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionCefamandole nafate 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionCefazolin sodium 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionCefoperazone sodium 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionCeforanide 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionCefotaxime sodium 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionCefoxitin sodium 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionCeftizoxime sodium 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionCefuroxime sodium 30 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionChloramphenicol sodium succinate 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionClindamycin phosphate 12 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionCo-trimoxazole 4/0.8 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionDoxycycline hyclate 1 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionErythromycin lactobionate 5 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionGentamicin sulfate 0.8 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionKanamycin sulfate 2.5 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionMetronidazole 5 mg/ml + Glucose 5%
Incompatible 0.2 mg/ml + InjectionMinocycline hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionMoxalactam 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionNafcillin sodium 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionOxacillin sodium 20 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionPenicillin G potassium 0.1 MUI/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionPiperacillin sodium 60 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionTobramycin sulfate 0.8 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionVancomycin hydrochloride 5 mg/ml + Glucose 5%
InjectionKanamycin sulfate Antibiotic
Compatible 2.5 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 2.5 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 2.5 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionMetronidazole Antiparasitic
Compatible 5 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionMinocycline hydrochloride Antibiotic
Incompatible 0.2 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Incompatible 0.2 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Incompatible 0.2 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionMorphine sulfate Analgesic
Compatible 1 mg/ml + InjectionAmikacin sulfate 5 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionAmpicillin sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionCefalotin sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionCefamandole nafate 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionCefazolin sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionCefoperazone sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionCeforanide 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionCefotaxime sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionCefoxitin sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionCeftizoxime sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionCefuroxime sodium 30 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionChloramphenicol sodium succinate 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionClindamycin phosphate 12 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionCo-trimoxazole 4/0.8 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionDoxycycline hyclate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionErythromycin lactobionate 5 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionGentamicin sulfate 0.8 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionKanamycin sulfate 2.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionMetronidazole 5 mg/ml + Glucose 5%
Incompatible 1 mg/ml + InjectionMinocycline hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionMoxalactam 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionNafcillin sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionOxacillin sodium 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionPenicillin G potassium 0.1 MUI/ml + Glucose 5%
Compatible 1 mg/ml + InjectionPiperacillin sodium 60 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionTobramycin sulfate 0.8 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionVancomycin hydrochloride 5 mg/ml + Glucose 5%
InjectionMoxalactam Antibiotic
Compatible 20 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionNafcillin sodium Antibiotic
Compatible 20 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Incompatible 20 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionOxacillin sodium Antibiotic
Compatible 20 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionPenicillin G potassium Antibiotic
Compatible 0.1 MUI/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 0.1 MUI/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 0.1 MUI/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionPethidine hydrochloride Analgesic
Compatible 10 mg/ml + InjectionAmikacin sulfate 5 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionCefalotin sodium 20 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionCefamandole nafate 20 mg/ml + Glucose 5%
Incompatible 10 mg/ml + InjectionCefoperazone sodium 20 mg/ml + Glucose 5%
Incompatible 10 mg/ml + InjectionCefoperazone sodium 20 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionCeforanide 20 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionCefotaxime sodium 20 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionCefoxitin sodium 20 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionCeftizoxime sodium 20 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionCefuroxime sodium 30 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionChloramphenicol sodium succinate 20 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionClindamycin phosphate 12 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionCo-trimoxazole 4/0.8 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionDoxycycline hyclate 1 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionErythromycin lactobionate 5 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionGentamicin sulfate 0.8 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionKanamycin sulfate 2.5 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionMetronidazole 5 mg/ml + Glucose 5%
Incompatible 10 mg/ml + InjectionMinocycline hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionMoxalactam 20 mg/ml + Glucose 5%
Incompatible 10 mg/ml + InjectionNafcillin sodium 20 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionOxacillin sodium 20 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionPenicillin G potassium 0.1 MUI/ml + Glucose 5%
Compatible 10 mg/ml + InjectionPiperacillin sodium 60 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionTobramycin sulfate 0.8 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionVancomycin hydrochloride 5 mg/ml + Glucose 5%
InjectionPiperacillin sodium Antibiotic
Compatible 60 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 60 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 60 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionTobramycin sulfate Antibiotic
Compatible 0.8 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 0.8 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 0.8 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionVancomycin hydrochloride Antibiotic
Compatible 5 mg/ml + InjectionHydromorphone hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%

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