Last update :
28/04/2024
References   References 62  
Type : Journal

Research teams : Charlottesville - University of Virginia Health Sciences Center, Department of Pharmacy
Authors : Pugh CB, Pabis DJ, Rodriguez C.
Title : Visual compatibility of morphine sulfate and meperidine hydrochloride with other injectable drugs during simulated Y-site injection.
Reference : Am J Hosp Pharm ; 48: 123-125. 1991

Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Not rated: compatibility study only

List of drugs
InjectionAciclovir sodium Antiviral
Incompatible 5 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Incompatible 5 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionAtenolol Beta-blocker
Compatible 0.5 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 0.5 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionAztreonam Antibiotic
Compatible 20 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionBumetanide Diuretic
Compatible 0.25 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 0.25 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionCeftazidime Antibiotic
Compatible 20 & 40 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 & 40 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionCeftriaxone disodium Antibiotic
Compatible 20 & 40 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 20 & 40 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 0.2 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionDigoxin Cardiotonic
Compatible 250 µg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 250 µg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionDiphenhydramine hydrochloride Antihistamine (H1)
Compatible 1&50 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionDobutamine hydrochloride Cardiotonic
Compatible 1 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionDopamine hydrochloride Cardiotonic
Compatible 1.6 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 1.6 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionDroperidol Neuroleptic
Compatible 2.5 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionFamotidine Antihistamine (H2)
Compatible 0.2 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionFluconazole Antifungal
Compatible 1 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionFurosemide Diuretic
Incompatible 0.8 >> 10 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Incompatible 2.4 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
Incompatible 10 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
Compatible 0.8 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionHydrocortisone sodium succinate Anti-inflammatory
Compatible 2 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionImipenem - cilastatin sodium Antibiotic
Incompatible 5 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionLabetalol hydrochloride Beta-blocker
Compatible 5 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionLidocaine hydrochloride Local anesthetic
Compatible 1 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionMethylprednisolone sodium succinate Anti-inflammatory
Compatible 2.5 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 2.5 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionMetoclopramide hydrochloride Antiemetic
Compatible 0.2 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 0.2 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionMetoprolol tartrate Anti-arrhythmic
Compatible 1 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionMorphine sulfate Analgesic
Compatible 1 mg/ml + Parenteral nutrition (binary mixture)
Incompatible 1 mg/ml + InjectionAciclovir sodium 5 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionAtenolol 0.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionAztreonam 20 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionBumetanide 0.25 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionCeftazidime 20 & 40 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionCeftriaxone disodium 20 & 40 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionDexamethasone sodium phosphate 0.2 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionDigoxin 250 µg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionDopamine hydrochloride 1.6 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionFamotidine 0.2 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionFluconazole 1 mg/ml + Glucose 5%
Incompatible 1 mg/ml + InjectionFurosemide 0.8 >> 10 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionLabetalol hydrochloride 5 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionLidocaine hydrochloride 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionMethylprednisolone sodium succinate 2.5 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionMetoclopramide hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionMetoprolol tartrate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionPropranolol hydrochloride 1 mg/ml + Glucose 5%
InjectionPethidine hydrochloride Analgesic
Compatible 10 mg/ml + Parenteral nutrition (binary mixture)
Incompatible 10 mg/ml + InjectionAciclovir sodium 5 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionAtenolol 0.5 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionAztreonam 20 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionBumetanide 0.25 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionCeftazidime 20 & 40 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionCeftriaxone disodium 20 & 40 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionDexamethasone sodium phosphate 0.2 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionDigoxin 250 µg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionDiphenhydramine hydrochloride 1&50 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionDobutamine hydrochloride 1 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionDopamine hydrochloride 1.6 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionDroperidol 2.5 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionFamotidine 0.2 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionFluconazole 1 mg/ml + Glucose 5%
Incompatible 10 mg/ml + InjectionFurosemide 2.4 mg/ml + Glucose 5%
Incompatible 10 mg/ml + InjectionFurosemide 10 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionFurosemide 0.8 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionHydrocortisone sodium succinate 2 mg/ml + Glucose 5%
Incompatible 10 mg/ml + InjectionImipenem - cilastatin sodium 5 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionLabetalol hydrochloride 5 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionLidocaine hydrochloride 1 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionMethylprednisolone sodium succinate 2.5 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionMetoclopramide hydrochloride 0.2 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionMetoprolol tartrate 1 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionPotassium chloride 400 mEq/l + Glucose 5%
Compatible 10 mg/ml + InjectionPropranolol hydrochloride 1 mg/ml + Glucose 5%
Compatible 10 mg/ml + InjectionVerapamil hydrochloride 2.5 mg/ml + Glucose 5%
InjectionPotassium chloride Electrolyte
Compatible 400 mEq/l + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionPropranolol hydrochloride Beta-blocker
Compatible 1 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 1 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%
InjectionVerapamil hydrochloride Anti-arrhythmic
Compatible 2.5 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Glucose 5%

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