Bibliographie - 57 - Stabilis 4.0

Last update :
06/05/2024

References 57

Type :

Journal

Web link :

http://www.ajhp.org/cgi/content/abstract/53/3/294

Research teams :

Hatfield - Mayron Research Laboratories

Authors :

Mayron D, Gennaro AR.

Title :

Stability and compatibility of granisetron hydrochloride in IV solutions and oral liquids and during simulated Y-site injection with selected drugs.

Reference :

Am J Health-Syst Pharm ; 53: 294-304. 1996

Level of Evidence :

Physical stability :

Chemical stability :

Stability defined as 95% of the initial concentration

High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)

Other methods :

Comments :

No comments for the degradation products

List of drugs

Carboplatin

1 mg/ml

Granisetron hydrochloride

1 mg/ml

Ceftazidime

16.7 mg/ml

Granisetron hydrochloride

1 mg/ml

Chlormethine hydrochloride

Cimetidine hydrochloride

3 mg/ml

Granisetron hydrochloride

1 mg/ml

Cisplatin

0.05 & 1 mg/ml

Granisetron hydrochloride

1 mg/ml

Cyclophosphamide

2 mg/ml

Granisetron hydrochloride

1 mg/ml

Cytarabine

2 mg/ml

Granisetron hydrochloride

1 mg/ml

Dacarbazine

1.7 mg/ml

Granisetron hydrochloride

1 mg/ml

Dexamethasone sodium phosphate

	0.24 mg/ml	+ Granisetron hydrochloride	0.02 mg/ml	+
	0.24 mg/ml	+ Granisetron hydrochloride	1 mg/ml	+

Diphenhydramine hydrochloride

1 mg/ml

Granisetron hydrochloride

1 mg/ml

Doxorubicin hydrochloride

0.2 mg/ml

Granisetron hydrochloride

1 mg/ml

Etoposide

0.4 mg/ml

Granisetron hydrochloride

1 mg/ml

Fluorouracil

2 mg/ml

Granisetron hydrochloride

1 mg/ml

Furosemide

0.4 mg/ml

Granisetron hydrochloride

1 mg/ml

Gentamicin sulfate

1.5 mg/ml

Granisetron hydrochloride

1 mg/ml

Granisetron hydrochloride


1 mg/ml			+
1 mg/ml	+ Carboplatin	1 mg/ml	+
1 mg/ml	+ Ceftazidime	16.7 mg/ml	+
1 mg/ml	+ Cimetidine hydrochloride	3 mg/ml	+
1 mg/ml	+ Cisplatin	0.05 & 1 mg/ml	+
1 mg/ml	+ Cyclophosphamide	2 mg/ml	+
1 mg/ml	+ Cytarabine	2 mg/ml	+
1 mg/ml	+ Dacarbazine	1.7 mg/ml	+
1 mg/ml	+ Dexamethasone sodium phosphate	0.24 mg/ml	+
0.02 mg/ml	+ Dexamethasone sodium phosphate	0.24 mg/ml	+
1 mg/ml	+ Diphenhydramine hydrochloride	1 mg/ml	+
1 mg/ml	+ Doxorubicin hydrochloride	0.2 mg/ml	+
1 mg/ml	+ Etoposide	0.4 mg/ml	+
1 mg/ml	+ Fluorouracil	2 mg/ml	+
1 mg/ml	+ Furosemide	0.4 mg/ml	+
1 mg/ml	+ Gentamicin sulfate	1.5 mg/ml	+
1 mg/ml	+ Hydromorphone hydrochloride	0.5 mg/ml	+
1 mg/ml	+ Ifosfamide	4 mg/ml	+
1 mg/ml	+ Lorazepam	0.1 mg/ml	+
1 mg/ml	+ Magnesium sulfate	16 mg/ml	+
1 mg/ml	+ Mesna	4 mg/ml	+
1 mg/ml	+ Methotrexate sodium	12.5 mg/ml	+
1 mg/ml	+ Morphine sulfate	1 mg/ml	+
1 mg/ml	+ Paclitaxel	0.29 mg/ml	+
1 mg/ml	+ Potassium chloride	40 mEq/l	+
1 mg/ml	+ Sodium bicarbonate	28.056 mg/ml	+
1 mg/ml	+ Streptozocin	9.1 mg/ml	+
1 mg/ml	+ Ticarcillin / clavulanic acid	26/0.89 mg/ml	+
1 mg/ml	+ Vincristine sulfate	0.01 & 0.34 mg/ml	+

Hydromorphone hydrochloride

0.5 mg/ml

Granisetron hydrochloride

1 mg/ml

Ifosfamide

4 mg/ml

Granisetron hydrochloride

1 mg/ml

Lorazepam

0.1 mg/ml

Granisetron hydrochloride

1 mg/ml

Magnesium sulfate

16 mg/ml

Granisetron hydrochloride

1 mg/ml

Mesna

4 mg/ml

Granisetron hydrochloride

1 mg/ml

Methotrexate sodium

12.5 mg/ml

Granisetron hydrochloride

1 mg/ml

Morphine sulfate

1 mg/ml

Granisetron hydrochloride

1 mg/ml

Paclitaxel

0.29 mg/ml

Granisetron hydrochloride

1 mg/ml

Potassium chloride

40 mEq/l

Granisetron hydrochloride

1 mg/ml

Sodium bicarbonate

28.056 mg/ml

Granisetron hydrochloride

1 mg/ml

Streptozocin

9.1 mg/ml

Granisetron hydrochloride

1 mg/ml

Ticarcillin / clavulanic acid

26/0.89 mg/ml

Granisetron hydrochloride

1 mg/ml

Vincristine sulfate

0.01 & 0.34 mg/ml

Granisetron hydrochloride

1 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Cyclophosphamide	1 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Cytarabine	1 mg/ml

20-23°C

Granisetron hydrochloride	0,5 mg/ml
Magnesium sulfate	8 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Doxorubicin hydrochloride	0,1 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Cisplatin	0,5 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Diphenhydramine hydrochloride	0,5 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Dacarbazine	0,85 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Dexamethasone sodium phosphate	0,12 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Fluorouracil	1 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Furosemide	0,2 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Hydromorphone hydrochloride	0,25 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Lorazepam	0,05 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Methotrexate sodium	6,25 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Morphine sulfate	0,5 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Carboplatin	0,5 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Ceftazidime	8,35 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Cimetidine hydrochloride	1,5 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Etoposide	0,2 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Gentamicin sulfate	0,75 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Ifosfamide	2 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Chlormethine hydrochloride	0,25 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Mesna	2 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Paclitaxel	0,145 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Streptozocin	4,55 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Ticarcillin / clavulanic acid	13/0,45 mg/ml

20°C-23°C

Granisetron hydrochloride	0,5 mg/ml
Vincristine sulfate	0,005 mg/ml

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