Last update :
17/04/2024
References   References 4326  
Type : Journal
Web link : https://doi.org/10.1691/p

Research teams : Marseille - Hôpital de la Conception
Authors : Curti C, Harti Souab K, Lamy E, Mathias F, Bornet C, Guinard B, Fersing C, Primas N, Albanèse J, Vanelle P.
Title : Stability studies of antipyocyanic beta-lactam antibiotics used in continuous infusion.
Reference : Pharmazie ; 74: 357-362. 2019

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionAztreonam Antibiotic
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 120 mg/ml 25°C Light
12 Hour
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 40 mg/ml 25°C Light
12 Hour
InjectionCefepime dihydrochloride Antibiotic
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 120 mg/ml 25°C Light
10 Hour
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 20 mg/ml 25°C Light
12 Hour
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 40 mg/ml 25°C Light
10 Hour
InjectionMeropenem Antibiotic
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 10 mg/ml 25°C Light
8 Hour
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 20 mg/ml 25°C Light
8 Hour
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 40 mg/ml 25°C Light
4 Hour
InjectionPiperacillin sodium / tazobactam Antibiotic
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 80 / 10 mg/ml 25°C Light
12 Hour

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