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References   References 3152  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/67/19/1640
Research teams : Minneapolis - University of Minnesotta, College of Pharmacy
Authors : Kumar A, Mann HJ.
Title : Visual compatibility of oritavancin diphosphate with selected coadministered drugs during simulated Y-site administration.
Reference : Am J Health-Syst Pharm ; 67: 1640-1644. 2010
Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Not rated: compatibility study only
List of drugs
InjectionAminophylline Various
Incompatible 1 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionAmphotericin B Antifungal
Incompatible 0.1 mg/ml + InjectionOritavancin 0.8>>2 mg/ml + Glucose 5%
InjectionAztreonam Antibiotic
Incompatible 20 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionBumetanide Diuretic
Incompatible 0.1 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionCalcium gluconate Electrolyte
Compatible 40 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionCimetidine hydrochloride Antihistamine (H2)
Compatible 12 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionCiprofloxacin lactate Antibiotic
Compatible 2 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionClindamycin phosphate Antibiotic
Incompatible 12 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionCo-trimoxazole Antibiotic
Incompatible 0.8/4 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionDexmedetomidine Sympathomimetic
Compatible 4 µg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionDobutamine hydrochloride Cardiotonic
Compatible 4 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionDopamine hydrochloride Cardiotonic
Compatible 3.2 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionEpinephrine hydrochloride Sympathomimetic
Compatible 40 µg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionFamotidine Antihistamine (H2)
Compatible 0.2 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionFentanyl citrate Analgesic
Compatible 50 µg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionFluconazole Antifungal
Compatible 2 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionFurosemide Diuretic
Incompatible 5 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionGentamicin sulfate Antibiotic
Compatible 5 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionHaloperidol lactate Neuroleptic
Compatible 1 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionHeparin sodium Anticoagulant
Incompatible 100 UI/ml + InjectionOritavancin 0.8 >>1.2 mg/ml + Glucose 5%
Incompatible 100 UI/ml + InjectionOritavancin 2 mg/ml + Glucose 5%
InjectionHydrocortisone sodium succinate Anti-inflammatory
Incompatible 1 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionInsulin Glucose-lowering
Compatible 1 UI/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionLorazepam Anxiolytic
Compatible 1 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionMeropenem Antibiotic
Incompatible 10 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionMetronidazole Antiparasitic
Compatible 5 mg/ml + InjectionOritavancin 0.8 >>1.2 mg/ml + Glucose 5%
Incompatible 5 mg/ml + InjectionOritavancin 2 mg/ml + Glucose 5%
InjectionMidazolam hydrochloride Anxiolytic
Compatible 1 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionMorphine sulfate Analgesic
Compatible 1 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionNitroglycerin Vasodilator
Compatible 0.4 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionNitroprusside sodium Vasodilator
Incompatible 0.4 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionNorepinephrine bitartrate Sympathomimetic
Compatible 0.12 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionOritavancin Antibiotic
Factors which affect stability Solvent NaHCO3 Induces Degradation
Incompatible 0.8 >>2 mg/ml + InjectionAminophylline 1 mg/ml + Glucose 5%
Incompatible 0.8>>2 mg/ml + InjectionAmphotericin B 0.1 mg/ml + Glucose 5%
Incompatible 0.8 >>2 mg/ml + InjectionAztreonam 20 mg/ml + Glucose 5%
Incompatible 0.8 >>2 mg/ml + InjectionBumetanide 0.1 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionCalcium gluconate 40 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionCimetidine hydrochloride 12 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionCiprofloxacin lactate 2 mg/ml + Glucose 5%
Incompatible 0.8 >>2 mg/ml + InjectionClindamycin phosphate 12 mg/ml + Glucose 5%
Incompatible 0.8 >>2 mg/ml + InjectionCo-trimoxazole 0.8/4 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionDexmedetomidine 4 µg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionDobutamine hydrochloride 4 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionDopamine hydrochloride 3.2 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionEpinephrine hydrochloride 40 µg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionFamotidine 0.2 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionFentanyl citrate 50 µg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionFluconazole 2 mg/ml + Glucose 5%
Incompatible 0.8 >>2 mg/ml + InjectionFurosemide 5 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionGentamicin sulfate 5 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionHaloperidol lactate 1 mg/ml + Glucose 5%
Incompatible 0.8 >>1.2 mg/ml + InjectionHeparin sodium 100 UI/ml + Glucose 5%
Incompatible 2 mg/ml + InjectionHeparin sodium 100 UI/ml + Glucose 5%
Incompatible 0.8 >>2 mg/ml + InjectionHydrocortisone sodium succinate 1 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionInsulin 1 UI/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionLorazepam 1 mg/ml + Glucose 5%
Incompatible 0.8 >>2 mg/ml + InjectionMeropenem 10 mg/ml + Glucose 5%
Incompatible 2 mg/ml + InjectionMetronidazole 5 mg/ml + Glucose 5%
Compatible 0.8 >>1.2 mg/ml + InjectionMetronidazole 5 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionMidazolam hydrochloride 1 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionMorphine sulfate 1 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionNitroglycerin 0.4 mg/ml + Glucose 5%
Incompatible 0.8 >>2 mg/ml + InjectionNitroprusside sodium 0.4 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionNorepinephrine bitartrate 0.12 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionPancuronium bromide 0.1 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionPhenylephrine hydrochloride 0.2 mg/ml + Glucose 5%
Incompatible 0.8 >>2 mg/ml + InjectionPhenytoin sodium 6 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionPotassium chloride 0.2 mEq/l + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionRanitidine hydrochloride 2 mg/ml + Glucose 5%
Incompatible 0.8 >>2 mg/ml + InjectionSodium bicarbonate 84 mg/ml + Glucose 5%
Compatible 0.8 >>2 mg/ml + InjectionTobramycin sulfate 5 mg/ml + Glucose 5%
InjectionPancuronium bromide Curarimimetic
Compatible 0.1 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionPhenylephrine hydrochloride Sympathomimetic
Compatible 0.2 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionPhenytoin sodium Antiepileptic
Incompatible 6 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionPotassium chloride Electrolyte
Compatible 0.2 mEq/l + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionRanitidine hydrochloride Antihistamine (H2)
Compatible 2 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionSodium bicarbonate Electrolyte
Incompatible 84 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
InjectionTobramycin sulfate Antibiotic
Compatible 5 mg/ml + InjectionOritavancin 0.8 >>2 mg/ml + Glucose 5%
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