Last update :
03/05/2024
References   References 2108  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=2393

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Trusley C, Kupiec TC, Trissel LA.
Title : Compatibility of micafungin injection with other drugs during simulated Y-site co-administration.
Reference : Int J Pharm Compound ; 10: 230-232. 2006

Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Not rated: compatibility study only

List of drugs
InjectionAminophylline Various
Compatible 2.5 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionAmiodarone hydrochloride Anti-arrhythmic
Incompatible 4 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionBumetanide Diuretic
Compatible 0.04 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionCalcium chloride Electrolyte
Compatible 40 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionCalcium gluconate Electrolyte
Compatible 40 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionCarboplatin Anticancer drug
Compatible 5 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionCiclosporin Immunosuppressant
Compatible 5 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionCisatracurium besylate Curarimimetic
Incompatible 0.5 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionDiltiazem hydrochloride Anti-arrhythmic
Incompatible 5 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionDobutamine hydrochloride Cardiotonic
Incompatible 4 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionDopamine hydrochloride Cardiotonic
Compatible 3.2 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionEpinephrine hydrochloride Sympathomimetic
Incompatible 50 µg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionEptifibatide Anticoagulant
Compatible 0.75 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionEsmolol hydrochloride Beta-blocker
Compatible 10 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionEtoposide Anticancer drug
Compatible 0.4 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionFenoldopam mesylate Vasodilator
Compatible 80 µg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionFurosemide Diuretic
Compatible 3 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionHeparin sodium Anticoagulant
Compatible 100 UI/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionHuman albumin Various
Incompatible 250 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionHydromorphone hydrochloride Analgesic
Compatible 0.5 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionInsulin Glucose-lowering
Incompatible 1 UI/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionLabetalol hydrochloride Beta-blocker
Incompatible 2 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionLidocaine hydrochloride Local anesthetic
Compatible 10 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionLorazepam Anxiolytic
Compatible 0.5 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionMagnesium sulfate Electrolyte
Compatible 100 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionMesna Cytoprotective
Compatible 20 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionMicafungin Antifungal
Compatible 1.5 mg/ml + Parenteral nutrition (binary mixture)
Compatible 1.5 mg/ml + InjectionAminophylline 2.5 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + InjectionAmiodarone hydrochloride 4 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionBumetanide 0.04 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionCalcium chloride 40 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionCalcium gluconate 40 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionCarboplatin 5 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionCiclosporin 5 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + InjectionCisatracurium besylate 0.5 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + InjectionDiltiazem hydrochloride 5 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + InjectionDobutamine hydrochloride 4 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionDopamine hydrochloride 3.2 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + InjectionEpinephrine hydrochloride 50 µg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionEptifibatide 0.75 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionEsmolol hydrochloride 10 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionEtoposide 0.4 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionFenoldopam mesylate 80 µg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionFurosemide 3 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionHeparin sodium 100 UI/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + InjectionHuman albumin 250 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionHydromorphone hydrochloride 0.5 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + InjectionInsulin 1 UI/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + InjectionLabetalol hydrochloride 2 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionLidocaine hydrochloride 10 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionLorazepam 0.5 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionMagnesium sulfate 100 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionMesna 20 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + InjectionMidazolam hydrochloride 2 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionMilrinone lactate 0.2 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + InjectionMorphine sulfate 15 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + InjectionMycophenolate mofetil 6 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + InjectionNesiritide 0.006 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + InjectionNicardipine hydrochloride 1 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionNitroglycerin 0.4 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionNitroprusside sodium 2 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionNorepinephrine bitartrate 0.128 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + InjectionOctreotide acetate 0.005 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + InjectionOndansetron hydrochloride 1 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + InjectionPethidine hydrochloride 10 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionPhenylephrine hydrochloride 1 mg/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + InjectionPhenytoin sodium 50 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionPotassium chloride 100 mEq/l + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionPotassium phosphate 0.5 mmol/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + InjectionRocuronium bromide 1 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionSodium Phosphate 0.5 mmol/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionTacrolimus 20 µg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionTheophylline 4 mg/ml + Sodium chloride 0,9%
Compatible 1.5 mg/ml + InjectionVasopressin 1 UI/ml + Sodium chloride 0,9%
Incompatible 1.5 mg/ml + InjectionVecuronium bromide 1 mg/ml + Sodium chloride 0,9%
InjectionMidazolam hydrochloride Anxiolytic
Incompatible 2 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionMilrinone lactate Cardiotonic
Compatible 0.2 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionMorphine sulfate Analgesic
Incompatible 15 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionMycophenolate mofetil Immunosuppressant
Incompatible 6 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionNesiritide Vasodilator
Incompatible 0.006 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionNicardipine hydrochloride Vasodilator
Incompatible 1 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionNitroglycerin Vasodilator
Compatible 0.4 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionNitroprusside sodium Vasodilator
Compatible 2 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionNorepinephrine bitartrate Sympathomimetic
Compatible 0.128 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionOctreotide acetate Various
Incompatible 0.005 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionOndansetron hydrochloride Antiemetic
Incompatible 1 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionPethidine hydrochloride Analgesic
Incompatible 10 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionPhenylephrine hydrochloride Sympathomimetic
Compatible 1 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionPhenytoin sodium Antiepileptic
Incompatible 50 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionPotassium chloride Electrolyte
Compatible 100 mEq/l + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionPotassium phosphate Electrolyte
Compatible 0.5 mmol/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionRocuronium bromide Curarimimetic
Incompatible 1 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionSodium Phosphate Electrolyte
Compatible 0.5 mmol/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionTacrolimus Immunosuppressant
Compatible 20 µg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionTheophylline Various
Compatible 4 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionVasopressin Hormone
Compatible 1 UI/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%
InjectionVecuronium bromide Curarimimetic
Incompatible 1 mg/ml + InjectionMicafungin 1.5 mg/ml + Sodium chloride 0,9%

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