Last update :
28/04/2024
References   References 1072  
Type : Journal

Research teams : Albany - Albany Medical Hospital Center
Authors : Saltsmann CL, Tom CM, Mitchell A, Fan JH, Gailey RA.
Title : Compatibility of levofloxacin with 34 medications during simulated Y-site administration.
Reference : Am J Health-Syst Pharm ; 56: 1458-1459. 1999

Level of Evidence : 
Not rated
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 
Not rated: compatibility study only

List of drugs
InjectionAciclovir sodium Antiviral
Incompatible 50 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionAlprostadil Vasodilator
Incompatible 500 µg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionAmikacin sulfate Antibiotic
Compatible 50 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionAminophylline Various
Compatible 25 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionAmpicillin sodium Antibiotic
Compatible 50 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionCaffeine Respiratory stimulant
Compatible 5 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionCefotaxime sodium Antibiotic
Compatible 200 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionCimetidine hydrochloride Antihistamine (H2)
Compatible 150 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionClindamycin phosphate Antibiotic
Compatible 150 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionDexamethasone sodium phosphate Anti-inflammatory
Compatible 4 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionDobutamine hydrochloride Cardiotonic
Compatible 12,5 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionDopamine hydrochloride Cardiotonic
Compatible 80 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionEpinephrine hydrochloride Sympathomimetic
Compatible 1000 µg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionFentanyl citrate Analgesic
Compatible 50 µg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionFurosemide Diuretic
Incompatible 10 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionGentamicin sulfate Antibiotic
Compatible 10 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionHeparin sodium Anticoagulant
Incompatible 10 UI/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionIndomethacin sodium trihydrate Anti-inflammatory
Incompatible 1 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionInsulin Glucose-lowering
Incompatible 100 UI/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
Incompatible 1 UI/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionIsoprenaline hydrochloride Beta-stimulant
Compatible 0,2 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionLevofloxacine Antibiotic
Incompatible 5 mg/ml + InjectionAciclovir sodium 50 mg/ml + Glucose 5%
Incompatible 5 mg/ml + InjectionAlprostadil 500 µg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionAmikacin sulfate 50 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionAminophylline 25 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionAmpicillin sodium 50 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionCaffeine 5 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionCefotaxime sodium 200 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionCimetidine hydrochloride 150 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionClindamycin phosphate 150 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionDexamethasone sodium phosphate 4 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionDobutamine hydrochloride 12,5 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionDopamine hydrochloride 80 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionEpinephrine hydrochloride 1000 µg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionFentanyl citrate 50 µg/ml + Glucose 5%
Incompatible 5 mg/ml + InjectionFurosemide 10 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionGentamicin sulfate 10 mg/ml + Glucose 5%
Incompatible 5 mg/ml + InjectionHeparin sodium 10 UI/ml + Glucose 5%
Incompatible 5 mg/ml + InjectionIndomethacin sodium trihydrate 1 mg/ml + Glucose 5%
Incompatible 5 mg/ml + InjectionInsulin 100 UI/ml + Glucose 5%
Incompatible 5 mg/ml + InjectionInsulin 1 UI/ml + Glucose 5%
Compatible 5 mg/ml + InjectionIsoprenaline hydrochloride 0,2 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionLidocaine hydrochloride 10 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionLorazepam 2 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionMetoclopramide hydrochloride 5 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionMorphine sulfate 4 mg/ml + Glucose 5%
Incompatible 5 mg/ml + InjectionNitroglycerin 5 mg/ml + Glucose 5%
Incompatible 5 mg/ml + InjectionNitroprusside sodium 10 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionOxacillin sodium 167 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionPancuronium bromide 1 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionPenicillin G sodium 0.5 MUI/ml + Glucose 5%
Compatible 5 mg/ml + InjectionPhenobarbital sodium 130 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionPhenylephrine hydrochloride 10 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionSodium bicarbonate 42 mg/ml + Glucose 5%
Compatible 5 mg/ml + InjectionVancomycin hydrochloride 50 mg/ml + Glucose 5%
InjectionLidocaine hydrochloride Local anesthetic
Compatible 10 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionLorazepam Anxiolytic
Compatible 2 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionMetoclopramide hydrochloride Antiemetic
Compatible 5 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionMorphine sulfate Analgesic
Compatible 4 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionNitroglycerin Vasodilator
Incompatible 5 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionNitroprusside sodium Vasodilator
Incompatible 10 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionOxacillin sodium Antibiotic
Compatible 167 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionPancuronium bromide Curarimimetic
Compatible 1 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionPenicillin G sodium Antibiotic
Compatible 0.5 MUI/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionPhenobarbital sodium Antiepileptic
Compatible 130 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionPhenylephrine hydrochloride Sympathomimetic
Compatible 10 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionSodium bicarbonate Electrolyte
Compatible 42 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%
InjectionVancomycin hydrochloride Antibiotic
Compatible 50 mg/ml + InjectionLevofloxacine 5 mg/ml + Glucose 5%

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